2,382 research outputs found

    Dielectric molding apparatus Patent

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    Dielectric apparatus for heating, fusing, and hardening of organic matrix to form plastic material into shaped produc

    When personal identities confirm versus conflict with group identities: Evidence from an intergroup paradigm

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    Permissions were not obtained for sharing the full text of this article.This study provides an experimental investigation of the consequences of conflict between children's personal identities and experimentally manipulated group identities. Elementary-school-aged children (N = 82, ages 5-11) attending a summer school program rated their own academic and athletic abilities and were then randomly assigned to one of two novel groups. Children's views of the academic and athletic skills of the novel groups were assessed both before and after information about the groups' academic and athletic skills was manipulated via posters placed in their classrooms. Following the manipulation, children's self-views, ingroup identification, and intergroup attitudes were assessed. Results indicated that (a) in the absence of information about the novel groups, children projected their personal identities onto their ingroup identities, (b) children maintained their ingroup identities in the face of new information that should have altered their ingroup identities, and (c) more positive personal identities predicted ingroup bias, which in turn predicted happiness with one's ingroup membership. The latter finding suggests that a tendency for children to generalize from their idiosyncratic positive self-views, rather than an indiscriminate desire for self-enhancement or positivity, may be responsible for ingroup bias

    Hypermultiplets and Topological Strings

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    The c-map relates classical hypermultiplet moduli spaces in compactifications of type II strings on a Calabi-Yau threefold to vector multiplet moduli spaces via a further compactification on a circle. We give an off-shell description of the c-map in N=2 superspace. The superspace Lagrangian for the hypermultiplets is a single function directly related to the prepotential of special geometry, and can therefore be computed using topological string theory. Similarly, a class of higher derivative terms for hypermultiplets can be computed from the higher genus topological string amplitudes. Our results provide a framework for studying quantum corrections to the hypermultiplet moduli space, as well as for understanding the black hole wave-function as a function of the hypermultiplet moduli.Comment: 21 pages, references adde

    Documentation of Apollo 15 samples

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    A catalog is presented of the documentation of Apollo 15 samples using photographs and verbal descriptions returned from the lunar surface. Almost all of the Apollo 15 samples were correlated with lunar surface photographs, descriptions, and traverse locations. Where possible, the lunar orientations of rock samples were reconstructed in the lunar receiving laboratory, using a collimated light source to reproduce illumination and shadow characteristics of the same samples shown in lunar photographs. In several cases, samples were not recognized in lunar surface photographs, and their approximate locations are known only by association with numbered sample bags used during their collection. Tables, photographs, and maps included in this report are designed to aid in the understanding of the lunar setting of the Apollo 15 samples

    Chronic exposure to MDMA (Ecstasy) elicits behavioral sensitization in rats but fails to induce cross-sensitization to other psychostimulants

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    BACKGROUND: The recreational use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) among adolescents and young adults has become increasingly prevalent in recent years. While evidence suggests that the long-term consequences of MDMA use include neurodegeneration to serotonergic and, possibly, dopaminergic pathways, little is known about susceptibility, such as behavioral sensitization, to MDMA. METHODS: The objectives of this study were to examine the dose-response characteristics of acute and chronic MDMA administration in rats and to determine whether MDMA elicits behavioral sensitization and whether it cross-sensitizes with amphetamine and methylphenidate. Adult male Sprague-Dawley rats were randomly divided into three MDMA dosage groups (2.5 mg/kg, 5.0 mg/kg, and 10.0 mg/kg) and a saline control group (N = 9/group). All three MDMA groups were treated for six consecutive days, followed by a 5-day washout, and subsequently re-challenged with their respective doses of MDMA (day 13). Rats were then given an additional 25-day washout period, and re-challenged (day 38) with similar MDMA doses as before followed by either 0.6 mg/kg amphetamine or 2.5 mg/kg methylphenidate on the next day (day 39). Open-field locomotor activity was recorded using a computerized automated activity monitoring system. RESULTS: Acute injection of 2.5 mg/kg MDMA showed no significant difference in locomotor activity from rats given saline (control group), while animals receiving acute 5.0 mg/kg or 10.0 mg/kg MDMA showed significant increases in locomotor activity. Rats treated chronically with 5.0 mg/kg and 10.0 mg/kg MDMA doses exhibited an augmented response, i.e., behavioral sensitization, on experimental day 13 in at least one locomotor index. On experimental day 38, all three MDMA groups demonstrated sensitization to MDMA in at least one locomotor index. Amphetamine and methylphenidate administration to MDMA-sensitized animals did not elicit any significant change in locomotor activity compared to control animals. CONCLUSION: MDMA sensitized to its own locomotor activating effects but did not elicit any cross-sensitization with amphetamine or methylphenidate

    Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea

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    Background: Environmental enteric dysfunction (EED) is widespread throughout the tropics and in children is associated with stunting and other adverse health outcomes. One of the hallmarks of EED is villus damage. In children with severe acute malnutrition (SAM) the severity of enteropathy is greater and short term mortality is high, but the metabolic consequences of enteropathy are unknown. Here, we characterize the urinary metabolic alterations associated with villus health, classic enteropathy biomarkers and anthropometric measurements in severely malnourished children in Zambia. Methods/Principal findings: We analysed 20 hospitalised children with acute malnutrition aged 6 to 23 months in Zambia. Small intestinal biopsies were assessed histologically (n = 15), anthropometric and gut function measurements were collected and the metabolic phenotypes were characterized by 1H nuclear magnetic resonance (NMR) spectroscopy. Endoscopy could not be performed on community controls children. Growth parameters were inversely correlated with enteropathy biomarkers (p = 0.011) and parameters of villus health were inversely correlated with translocation and permeability biomarkers (p = 0.000 and p = 0.015). Shorter villus height was associated with reduced abundance of metabolites related to gut microbial metabolism, energy and muscle metabolism (p = 0.034). Villus blunting was also related to increased sucrose excretion (p = 0.013). Conclusions/Significance: Intestinal villus blunting is associated with several metabolic perturbations in hospitalized children with severe undernutrition. Such alterations include altered muscle metabolism, reinforcing the link between EED and growth faltering, and a disruption in the biochemical exchange between the gut microbiota and host. These findings extend our understanding on the downstream consequences of villus blunting and provide novel non-invasive biomarkers of enteropathy dysfunction. The major limitations of this study are the lack of comparative control group and gut microbiota characterization

    Ricci-flat supertwistor spaces

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    We show that supertwistor spaces constructed as a Kahler quotient of a hyperkahler cone (HKC) with equal numbers of bosonic and fermionic coordinates are Ricci-flat, and hence, Calabi-Yau. We study deformations of the supertwistor space induced from deformations of the HKC. We also discuss general infinitesimal deformations that preserve Ricci-flatness.Comment: 13 pages, references and comments adde

    Comportamento de genótipos de canola em Maringá em 2003.

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