Determinasi Informasi Karir, Bimbingan Karir Dan Ekspektasi Karir Terhadap Kompetensi Lulusan SMALB Di SLB.B Negeri Pembina Tingkat Nasional Jimbaran.

Tujuan penelitian ini untuk mengkaji determinasi informasi karir, bimbingan karir dan ekspektasi karir terhadap kompetensi lulusan SMALB. Data penelitian menggunakan kuesioner model Skala Likert. Uji validitas butir dihitung dengan koefisien korelasi Product Moment. Uji persyaratan analisis untuk normalitas sebaran data memakai uji Kolmogorov-Smirnov. Penelitian ini menggunakan pendekatan ex-post facto, dengan sampel 41 orang siswa SMALB di SLB.B N PTN Jimbaran. Untuk menjaring data digunakan instrument berbentuk kuesioner. Pengolahan data menggunakan metode deskriptif dan kuantitatif dengan uji statistik. Hasil analisis data menunjukkan: 1) Terdapat determinasi positif dan signifikan antara informasi karir terhadap kompetensi lulusan SMALB sebesar 1,51%. 2) Terdapat determinasi positif dan signifikan antara bimbingan karir terhadap kompetensi lulusan SMALB sebesar 22,18%. 3) Terdapat determinasi positif dan signifikan antara ekspektasi karir terhadap kompetensi lulusan SMALB sebesar 43,83%. 4) Secara bersama-sama terdapat determinasi positif dan signifikan antara informasi karir, bimbingan karir dan ekspektasi karir terhadap kompetensi lulusan sebesar 20,16% dengan sumbangan efektif masing-masing X1 55.604, X2 38.474, X3 74.580. 5) Penelitian juga membuktikan bahwa berdasarkan besarnya korelasi parsial, ternyata determinasi ekspektasi karir menduduki peringkat pertama dengan koefisien determinasi 43,83%, dan bimbingan karir terhadap kompetensi lulusan menduduki peringkat ke dua dengan determinasi 22,18%, dan informasi karir menduduki peringkat ketiga dengan koefisien determinasi 20,16.Kata Kunci : Informasi Karir, Bimbingan Karir, Ekspektasi Karir, Kompetensi Lulusan The purpose of this research is to examine career information determination, career counseling and career expectation towards competency for the SMALB graduates. Research data were by using questionnaires model of Likert\u27s Scale. Ex-post facto approach has been used for this research by using sample of total 41 students of SMALB at SLB.B N PTN Jimbaran. Questionnaires were used as an instrument to collect the data for this research. Descriptive method has been used in data processing and quantitative method for statistic test. Validity test was made by using product moment correlation coefficient with Kolmogorov-Smirnov. Test was used to determinate the normal distributing data, and homogeneity Scatterplot was used to judge the homogeneity of varians the result of this study showed that: 1) There was a positive and significant determination between career information toward the graduates competency, with coefficient correlation is 1,51%. 2) There was a positive and significant determination between career counseling toward the graduates competency, with coefficient correlation is 22,18%. 3) There was a positive and significant determination between career information toward the graduates competency, with coefficient correlation is 43,83%. 4) There was a simultance us determination of the carrier information, carrier counseling, and career expectation, welfare toward the graduates competency, with doubel correlation is 20,16% and effektif support are X138.474, X2 55,604%, X3 74,580. 5) The study also proves that based on the magnitude of the partial correlation, it turns out the career expectations of determination was ranked first with is 43,83% % coefficient of determination , and the determination of the competence of graduate career guidance SMALB was ranked second with 22,18 % determination , and career information ranks third with a coefficient of determination of 20,16%.keyword : Career information, career counseling, career expectation, competention

Management of Glaucoma in Pregnancy

Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patient health decisions begin even prior to conception and continue throughout pregnancy and breastfeeding. Data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Our review suggests that individually, intraocular pressure is lower in a pregnant woman when compared to a non-pregnant woman. Importantly, the medical management of glaucoma during pregnancy poses special challenges due to the possibility of adverse effects of medications on the fetus and newborn. Laser trabeculoplasty and traditional filtration surgery, as well as minimally invasive glaucoma surgery, represent non-drug management options. Thus, managing glaucoma in pregnancy is a delicate balance between treatment to prevent damage to the optic nerve in the mother and avoidance of interventions potentially harmful to the fetus. This literature review of published individual and population-based studies was performed in order to explore current knowledge and guidelines in the management of glaucoma in pregnancy

Desain pengembangan fasilitas sekolah di era revolusi industri 4.0

Kebijakan yang relevan dan baik selalu ditopang oleh suatu kajian yang baik pula. Artinya selalu ada korelasi positif antara suatu kajian yang berbasis penelitian akademik dengan kebijakan apa yang diambil. Tentu dalam konteks ini adalah yang ada kaitannya dengan pengembangan SMK ke depannya. Kajian NSPK ini bertujuan tidak lain untuk menjawab hal tersebut. Tuntutan pembaharuan kebijakan ditengah arus dan gelombang modernisasi yang semakin dinamis sangat diperlukan terlebih perkembangan revolusi Industri sudah mencapai 4.0 yang berbasis cyber physical system ini. Revolusi industrisangat memiliki keterkaitan dengan Sekolah Menengah Kejuruan salah satunya pada aspek penggunaan peralatan praktik sebagai penunjang kompetensi siswa. Inti dari praktik siswa adalah memberikan kemampuan practical dalam penguasaan penggunaan peralatan praktik, semakin alat yang dimiliki relevan dengan perkembangan zaman semakin membantu pula peserta didik dalam upgrading skill-nya

Oral Ferrous Sulphate Improves Functional Capacity on Heart Failure Patients with Iron Deficiency Anemia

Background: Iron deficiency anemia (IDA) in heart failure (HF) is associated with poor functional capacity. Several studies reported the benefit of iron therapy in HF with IDA on improving functional capacity. Therefore, we attempt to investigate the effect of oral iron supplementation on functional capacity in HF patients with IDA. Results: Double blind randomized controlled trial was conducted in National Cardiovascular Center Harapan Kita Hospital Universitas Indonesia. A total 54 HFREF patients with IDA were enrolled and randomized to either oral Ferrous Sulphate (FS) 200mg 3 times a day or placebo with 1:1 ratio for 12 weeks. Primary outcome was functional capacity measured by 6-minute walk test. There were 41 participants completed the study (FS n=22, placebo n=19). Ferrous sulphate significantly improved functional capacity changes (46.23+35m vs -13.7+46m, p<0.001, CI -86.8 to -33.2) compared with placebo groups respectively after 12 weeks intervention. Conclusions: Oral FS supplementation for 12 weeks significantly improved functional capacity in HF patients with IDA. Trial registration: clinicaltrials.gov, NCT02998697. Registered 14 December 2016 - Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT0299869

Genetic factors associated with patient-specific warfarin dose in ethnic Indonesians

<p>Abstract</p> <p>Background</p> <p><it>CYP2C9 </it>and <it>VKORC1 </it>are two major genetic factors associated with inter-individual variability in warfarin dose. Additionally, genes in the warfarin metabolism pathway have also been associated with dose variance. We analyzed Single Nucleotide Polymorphisms (SNPs) in these genes to identify genetic factors that might confer warfarin sensitivity in Indonesian patients.</p> <p>Methods</p> <p>Direct sequencing method was used to identify SNPs in <it>CYP2C9, VKORC1, CYP4F2, EPHX1, PROC </it>and <it>GGCX </it>genes in warfarin-treated patients. Multiple linear regressions were performed to model the relationship warfarin daily dose requirement with genetic and non-genetic variables measured and used to develop a novel algorithm for warfarin dosing.</p> <p>Results</p> <p>From the 40 SNPs analyzed, <it>CYP2C9 </it>rs17847036 and <it>VKORC1 </it>rs9923231 showed significant association with warfarin sensitivity. In our study population, no significant correlation could be detected between <it>CYP2C9*3, CYP2C9C</it>-65 (rs9332127), <it>CYP4F2 </it>rs2108622, <it>GGCX </it>rs12714145, <it>EPHX1 </it>rs4653436 and <it>PROC </it>rs1799809 with warfarin sensitivity.</p> <p>Conclusions</p> <p><it>VKORC1 </it>rs9923231 AA and <it>CYP2C9 </it>rs17847036 GG genotypes were associated with low dosage requirements of most patients (2.05 ± 0.77 mg/day and 2.09 ± 0.70 mg/day, respectively). <it>CYP2C9 </it>and <it>VKORC1 </it>genetic variants as well as non-genetic factors such as age, body weight and body height account for 15.4% of variance in warfarin dose among our study population. Additional analysis of this combination could allow for personalized warfarin treatment in ethnic Indonesians.</p