Depositing catalyst layers in polymer electrolyte membrane fuel cells : a review

Fuel cell technology continues to advance and offers to be a potentially promising solution to many energy needs. Of particular interest are manufacturing techniques to improve performance and decrease overall cost. For catalyst deposition on the membrane electrode assembly (MEA), there are a number of techniques that have been used in the past decades. This paper aims to review many of these main techniques that have been published to show the wide variety of catalyst deposition methods

The House of Security: Stakeholder Perceptions of Security Assessment and Importance

In this paper we introduce a methodology for analyzing differences regarding security perceptions within and between stakeholders, and the elements which affect these perceptions. We have designed the “House of Security”, a security assessment model that provides the basic framework for considering eight different constructs of security: Vulnerability, Accessibility, Confidentiality, Technology Resources for Security, Financial Resources for Security, Business Strategy for Security, Security Policy and Procedures, and Security Culture. We designed and performed a survey of about 1500 professionals in various industries, levels, and functions resulting in a gap analysis to uncover differences (1) between the different constructs and aspects of security, (2) between different enterprise stakeholder roles, and (3) between different organizations. This paper briefly describes the development of the security constructs and some of the preliminary findings

Kinematics of Spiral Arm Streaming in M51

We use CO and H alpha velocity fields to study the gas kinematics in the spiral arms and interarms of M51 (NGC 5194), and fit the 2D velocity field to estimate the radial and tangential velocity components as a function of spiral phase (arm distance). We find large radial and tangential streaming velocities, which are qualitatively consistent with the predictions of density wave theory and support the existence of shocks. The streaming motions are complex, varying significantly across the galaxy as well as along and between arms. Aberrations in the velocity field indicate that the disk is not coplanar, perhaps as far in as 20\arcsec\ (800 pc) from the center. Velocity profile fits from CO and H alpha are typically similar, suggesting that most of the H alpha emission originates from regions of recent star formation. We also explore vortensity and mass conservation conditions. Vortensity conservation, which does not require a steady state, is empirically verified. The velocity and density profiles show large and varying mass fluxes, which are inconsistent with a steady flow for a single dominant global spiral mode. We thus conclude that the spiral arms cannot be in a quasi-steady state in any rotating frame, and/or that out of plane motions may be significant.Comment: 50 pages, including 20 figures; Accepted for publication in ApJ. PDF version with high resolution figures available at http://www.astro.umd.edu/~shetty/Research

House of Security: Locale, Roles and Resources for Ensuring Information Security Research-in-Progress

In this paper we redefine information security by extending its definition in three salient avenues: locale (beyond the boundary of an enterprise to include partner organizations), role (beyond the information custodians’ view to include information consumers’ and managers’ views), and resource (beyond technical dimensions to include managerial dimensions). Based on our definition, we develop a model of information security, which we call the House of Security. This model has eight constructs, Vulnerability, Accessibility, Confidentiality, IT Resources for Security, Financial Resources for Security, Business Strategy for Security, Security Policy and Procedures, and Security Culture. We have developed a questionnaire to measure the assessment and importance of information security along these eight aspects. The questionnaire covers multiple locales and questionnaire respondents cover multiple roles. Data collection is currently in process. Results from our analysis of the collected data will be ready for presentation at the conference

Measuring Stakeholders’ Perceptions of Cybersecurity for Renewable Energy Systems

Renewable energy systems need to be able to make frequent and rapid adjustments to address shifting solar and wind production. This requires increasingly sophisticated industrial control systems (ICS). But, that also increases the potential risks from cyber-attacks. Despite increasing attention to technical aspects (i.e., software and hardware) of cybersecurity, many professionals and scholars pay little or no attention to its organizational aspects, particularly to stakeholders’ perceptions of the status of cybersecurity within organizations. Given that cybersecurity decisions and policies are mainly made based on stakeholders’ perceived needs and security views, it is critical to measure such perceptions. In this paper, we introduce a methodology for analyzing differences in perceptions of cybersecurity among organizational stakeholders. To measure these perceptions, we first designed House of Security (HoS) as a framework that includes eight constructs of security: confidentiality, integrity, availability, technology resources, financial resources, business strategy, policy and procedures, and culture. We then developed a survey instrument to analyze stakeholders’ perceptions based on these eight constructs. In a pilot study, we used the survey with people in various functional areas and levels of management in two energy and ICS organizations, and conducted a gap analysis to uncover differences in cybersecurity perceptions. This paper introduces the HoS and describes the survey instrument, as well as some of the preliminary findings. Keywords: Smart Grid; Functional Area; Operational Technology; Organizational Aspect; Renewable Energy Resourc

CO Detection and Millimeter Continuum Emission from Low Surface Brightness Galaxies

We present BIMA and IRAM CO(1--0) observations of seven low surface brightness (LSB) galaxies, including three large spirals with faint disks but prominent bulges, and four relatively small LSB galaxies with irregular disks. The giant LSB galaxies are UGC 5709, UGC 6614 and F568-6 (Malin2). The smaller LSB galaxies are NGC 5585, UGC 4115, UGC 5209 and F583-1. The galaxies were selected based on their relatively high metallicity and apparent signs of star formation in their disks. The BIMA maps suggested the presence of molecular gas in 2 of the giant LSB galaxies, F568-6 and UGC 6614. Using the 30m IRAM telescope we detected CO (1--0) emission in the disks of both galaxies and in the nucleus of F568-6. The molecular gas in these galaxies is clearly offset from the nucleus and definitely associated with the LSB disk. In addition we also detected a millimeter continuum source in the center of UGC 6614. When compared with VLA 1.5 GHz observations of the galaxy, the emission was found to have a flat spectrum indicating that the millimeter continuum emission is most likely due to an active galactic nucleus (AGN) in the galaxy. Our results show that giant LSB spirals may contain significant quantities of molecular gas in their disks and also harbor radio bright AGN in their centers

High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus

Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin. A number of C-type lectins recognise oligosaccharides rich in mannose and fucose – sugars with similar structures to glucose. This raises the possibility that high glucose conditions in diabetes affect protein-oligosaccharide interactions via competitive inhibition. Mannose binding lectin, soluble DC-SIGN & DC-SIGNR, and surfactant protein D, were tested for carbohydrate binding in the presence of glucose concentrations typical of diabetes, via surface plasmon resonance and affinity chromatography. Complement activation assays were performed in high glucose. DC-SIGN and DC-SIGNR expression in adipose tissues was examined via immunohistochemistry. High glucose inhibited C-type lectin binding to high-mannose glycoprotein and binding of DC-SIGN to fucosylated ligand (blood group B) was abrogated in high glucose. Complement activation via the lectin pathway was inhibited in high glucose and also in high trehalose - a nonreducing sugar with glucoside stereochemistry. DC-SIGN staining was seen on cells with DC morphology within omental and subcutaneous adipose tissues. We conclude that high glucose disrupts C-type lectin function, potentially illuminating new perspectives on susceptibility to infectious and inflammatory disease in diabetes. Mechanisms involve competitive inhibition of carbohydrate-binding within sets of defined proteins, in contrast to broadly indiscriminate, irreversible glycation of proteins

Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10

The process of antibody ontogeny typically improves affinity, on-rate, and thermostability, narrows polyspecificity, and rigidifies the combining site to the conformer optimal for binding from the broader ensemble accessible to the precursor. However, many broadly-neutralizing anti-HIV antibodies incorporate unusual structural elements and recognition specificities or properties that often lead to autoreactivity. The ontogeny of 4E10, an autoreactive antibody with unexpected combining site flexibility, was delineated through structural and biophysical comparisons of the mature antibody with multiple potential precursors. 4E10 gained affinity primarily by off-rate enhancement through a small number of mutations to a highly conserved recognition surface. Controverting the conventional paradigm, the combining site gained flexibility and autoreactivity during ontogeny, while losing thermostability, though polyspecificity was unaffected. Details of the recognition mechanism, including inferred global effects due to 4E10 binding, suggest that neutralization by 4E10 may involve mechanisms beyond simply binding, also requiring the ability of the antibody to induce conformational changes distant from its binding site. 4E10 is, therefore, unlikely to be re-elicited by conventional vaccination strategies

Panmicrobial oligonucleotide array for diagnosis of infectious diseases

To facilitate rapid, unbiased, differential diagnosis of infectious diseases, we designed GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites. Methods for nucleic acid preparation, random primed PCR amplification, and labeling were optimized to allow the sensitivity required for application with nucleic acid extracted from clinical materials and cultured isolates. Analysis of nasopharyngeal aspirates, blood, urine, and tissue from persons with various infectious diseases confirmed the presence of viruses and bacteria identified by other methods, and implicated Plasmodium falciparum in an unexplained fatal case of hemorrhagic feverlike disease during the Marburg hemorrhagic fever outbreak in Angola in 2004-2005

Revival of the magnetar PSR J1622-4950: observations with MeerKAT, Parkes, XMM-Newton, Swift, Chandra, and NuSTAR

New radio (MeerKAT and Parkes) and X-ray (XMM-Newton, Swift, Chandra, and NuSTAR) observations of PSR J1622-4950 indicate that the magnetar, in a quiescent state since at least early 2015, reactivated between 2017 March 19 and April 5. The radio flux density, while variable, is approximately 100x larger than during its dormant state. The X-ray flux one month after reactivation was at least 800x larger than during quiescence, and has been decaying exponentially on a 111+/-19 day timescale. This high-flux state, together with a radio-derived rotational ephemeris, enabled for the first time the detection of X-ray pulsations for this magnetar. At 5%, the 0.3-6 keV pulsed fraction is comparable to the smallest observed for magnetars. The overall pulsar geometry inferred from polarized radio emission appears to be broadly consistent with that determined 6-8 years earlier. However, rotating vector model fits suggest that we are now seeing radio emission from a different location in the magnetosphere than previously. This indicates a novel way in which radio emission from magnetars can differ from that of ordinary pulsars. The torque on the neutron star is varying rapidly and unsteadily, as is common for magnetars following outburst, having changed by a factor of 7 within six months of reactivation.Comment: Published in ApJ (2018 April 5); 13 pages, 4 figure