1,136 research outputs found
Tunable gauge potential for neutral and spinless particles in driven lattices
We present a universal method to create a tunable, artificial vector gauge
potential for neutral particles trapped in an optical lattice. The necessary
Peierls phase of the hopping parameters between neighboring lattice sites is
generated by applying a suitable periodic inertial force such that the method
does not rely on any internal structure of the particles. We experimentally
demonstrate the realization of such artificial potentials, which generate
ground state superfluids at arbitrary non-zero quasi-momentum. We furthermore
investigate possible implementations of this scheme to create tuneable magnetic
fluxes, going towards model systems for strong-field physics
The spatial distribution of sedimentary compounds and their environmental implications in surface sediments of Lake Khar Nuur (Mongolian Altai)
Lake sediments are valuable natural archives to reconstruct paleoclimate and paleoenvironmental changes which consist of inorganic and organic sediment compounds of allochthonous origin from the catchment and of autochthonous production in the lake. However, for robust paleo-reconstructions it is important to develop a better understanding about sedimentation processes, the origin of inorganic and organic sediment compounds and their distribution within the lake. In this context, modern process studies provide important insights, although environmental and anthropological changes can affect the spatial distribution of sediment compounds through time. Therefore, in this study the spatial distribution of grain size and geochemical proxies in 52 surface sediment samples from Lake Khar Nuur, a small high-altitude lake in the Mongolian Altai with a small and anthropogenically used hydrological catchment, is investigated. The results show a distinct sediment focussing in the two deep basins of the lake, which therefore act as accumulation zones. In those accumulation zones, total organic carbon (TOC), total nitrogen (N) and their isotopic composition (δ13CTOC, δ15N) as well as n-alkanes indicate that organic sediment compounds are a mixture of both allochthonous and autochthonous origin. While the recent catchment vegetation consists of grasses/herbs and the shrub Betula nana (L.) with distinct differences in their n-alkane homologue patterns, those differences are not reflected in the sediment surface samples which rather indicates that grass-derived n-alkanes become preferentially incorporated in the lake. Extensive anthropogenic activity such as grazing and housing in the southern part of the catchment causes soil erosion which is well reflected by high TOC, N and sulphur (S) contents and 15N depleted δ15N values at the central southern shore, i.e. increased allochthonous sediment input by anthropogenicallyinduced soil erosion. Overall, the surface sediments of Lake Khar Nuur origin from allochthonous and autochthonous sources and are focussed in the accumulation zones of the lake, while their distribution is both environmentally and anthropogenically driven
The Coagulation Box and a New Hemoglobin-Driven Algorithm for Bleeding Control in Patients with Severe Multiple Traumas
Background: Extensive hemorrhage is the leading cause of death in the first few hours following multiple traumas. Therefore, early and aggressive treatment of clotting disorders could reduce mortality. Unfortunately, the availability of results from commonly performed blood coagulation studies are often delayed whereas hemoglobin (Hb) levels are quickly available.
Objectives: In this study, we evaluated the use of initial hemoglobin (Hb) levels as a guide line for the initial treatment of clotting disorders in multiple trauma patients.
Patients and Methods: We have developed an Hb-driven algorithm to initiate the initial clotting therapy. The algorithm contains three different steps for aggressive clotting therapy depending on the first Hb value measured in the shock trauma room, (SR) and utilizes fibrinogen, prothrombin complex concentrate (PCC), factor VIIa, tranexamic acid and desmopressin. The above-mentioned drugs were stored in a special “coagulation box” in the hospital pharmacy, and this box could be immediately brought to the SR or operating room (OR) upon request. Despite the use of clotting factors, transfusions using red blood cells (RBC) and fresh frozen plasma (FFP) were performed at an RBC-to-FFP ratio of 2:1 to 1:1.
Results: Over a 12-month investigation period, 123 severe multiple trauma patients needing intensive care therapy were admitted to our trauma center (mean age 48 years, mean ISS (injury severity score) 30). Fourteen (11%) patients died; 25 (mean age 51.5 years, mean ISS 53) of the 123 patients were treated using the “coagulation box,” and 17 patients required massive transfusions. Patients treated with the “coagulation box” required an average dose of 16.3 RBC and 12.9 FFP, whereas 17 of the 25 patients required an average dose of 3.6 platelet packs. According to the algorithm, 25 patients received fibrinogen (average dose of 8.25 g), 24 (96%) received PCC (3000 IU.), 14 (56%) received desmopressin (36.6 µg), 13 (52%) received tranexamic acid (2.88 g), and 11 (44%) received factor VIIa (3.7 mg). The clotting parameters markedly improved between SR admission and ICU admission. Of the 25 patients, 16 (64%) survived. The revised injury severity classification (RISC) predicted a survival rate of 41%, which corresponds to a standardized mortality ratio (SMR) of 0.62, which implies a higher survival rate than predicted.
Conclusions: An Hb-driven algorithm, in combination with the “coagulation box” and the early use of clotting factors, could be a simple and effective tool for improving coagulopathy in multiple trauma patients
Quantum simulation of frustrated magnetism in triangular optical lattices
Magnetism plays a key role in modern technology as essential building block
of many devices used in daily life. Rich future prospects connected to
spintronics, next generation storage devices or superconductivity make it a
highly dynamical field of research. Despite those ongoing efforts, the
many-body dynamics of complex magnetism is far from being well understood on a
fundamental level. Especially the study of geometrically frustrated
configurations is challenging both theoretically and experimentally. Here we
present the first realization of a large scale quantum simulator for magnetism
including frustration. We use the motional degrees of freedom of atoms to
comprehensively simulate a magnetic system in a triangular lattice. Via a
specific modulation of the optical lattice, we can tune the couplings in
different directions independently, even from ferromagnetic to
antiferromagnetic. A major advantage of our approach is that standard
Bose-Einstein-condensate temperatures are sufficient to observe magnetic
phenomena like N\'eel order and spin frustration. We are able to study a very
rich phase diagram and even to observe spontaneous symmetry breaking caused by
frustration. In addition, the quantum states realized in our spin simulator are
yet unobserved superfluid phases with non-trivial long-range order and
staggered circulating plaquette currents, which break time reversal symmetry.
These findings open the route towards highly debated phases like spin-liquids
and the study of the dynamics of quantum phase transitions.Comment: 5 pages, 4 figure
Large-scale Star Formation Triggering in the Low-mass Arp 82 System: A Nearby Example of Galaxy Downsizing Based on UV/Optical/Mid-IR Imaging
As part of our Spitzer Spirals, Bridges, and Tails project to help understand
the effects of galaxy interactions on star formation, we analyze GALEX
ultraviolet, SARA optical, and Spitzer infrared images of the interacting
galaxy pair Arp 82 (NGC 2535/6) and compare to a numerical simulation of the
interaction. We investigate the multiwavelength properties of several
individual star forming complexes (clumps). Using optical and UV colors,
EW(Halpha), and population synthesis models we constrain the ages of the clumps
and find that the median clump age is about 12 Myr. The clumps have masses
ranging from a few times 10^6 to 10^9 solar masses. In general, the clumps in
the tidal features have similar ages to those in the spiral region, but are
less massive. The 8 micron and 24 micron luminosities are used to estimate the
far-infrared luminosities and the star formation rates of the clumps. The total
clump star formation rate is 2.0+/-0.8 solar masses per year, while the entire
Arp 82 system is forming stars at a rate of 4.9+/-2.0 solar masses per year. We
find, for the first time, stars in the HI arc to the southeast of the NGC 2535
disk. Population synthesis models indicate that all of the observed populations
have young to intermediate ages. We conclude that although the gas disks and
some old stars may have formed early-on, the progenitors are late-type or low
surface brightness and the evolution of these galaxies was halted until the
recent encounter.Comment: Accepted for publication in the AJ, 22 Figures, 5 Table
A Warp in Progress : H I and Radio Continuum Observations of the Spiral NGC 3145
Date of Acceptance: 16/06/2015We present VLA H I and 6 cm radio continuum observations of the spiral NGC 3145 and H I observations of its two companions, NGC 3143 and PGC 029578. In optical images NGC 3145 has stellar arms that appear to cross, forming "X"-features. Our radio continuum observations rule out shock fronts at 3 of the 4 "X"-features. In the middle-to-outer disk, the H I line-profiles of NGC 3145 are skewed. Relative to the disk, the gas in the skewed wing of the line-profiles has z-motions away from us on the approaching side of the galaxy and z-motions of about the same magnitude (about 40 km/s) towards us on the receding side. These warping motions imply that there has been a perturbation with a sizeable component perpendicular to the disk over large spatial scales. Two features in NGC 3145 have velocities indicating that they are out-of-plane tidal arms. One is an apparent branch of a main spiral arm; the velocity of the branch is 150 km/s greater than the spiral arm where they appear to intersect in projection. The other is an arm that forms 3 of the "X"-features. It differs in velocity by 56 km/s from the disk at the same projected location. Based on its SFR and H I properties, NGC 3143 is the more likely of the two companions to have interacted with NGC 3145 recently. A simple analytic model demonstrates that an encounter between NGC 3143 and NGC 3145 is a plausible explanation for the observed warping motions in NGC 3145.Peer reviewe
Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality
BACKGROUND: Oxidative stress has been suggested to play a key role in the development of cardiovascular disease (CVD). The aim of our study was to investigate the associations of serum peroxiredoxin 4 (Prx4), a hydrogen peroxide-degrading peroxidase, with incident CVD and all-cause mortality. We subsequently examined the incremental value of Prx4 for the risk prediction of CVD compared with the Framingham risk score (FRS). METHODS AND RESULTS: We performed Cox regression analyses in 8141 participants without history of CVD (aged 28 to 75 years; women 52.6%) from the Prevention of Renal and Vascular End-stage Disease (PREVEND) study in Groningen, The Netherlands. Serum Prx4 was measured by an immunoluminometric assay in baseline samples. Main outcomes were: (1) incident CVD events or CVD mortality and (2) all-cause mortality during a median follow-up of 10.5 years. In total, 708 participants (7.8%) developed CVD events or CVD mortality, and 517 participants (6.3%) died. Baseline serum Prx4 levels were significantly higher in participants with incident CVD events or CVD mortality and in those who died than in participants who remained free of outcomes (both P<0.001). In multivariable models with adjustment for Framingham risk factors, hazard ratios were 1.16 (95% CI 1.06 to 1.27, P<0.001) for incident CVD events or CVD mortality and 1.17 (95% CI 1.06 to 1.29, P=0.003) for all-cause mortality per doubling of Prx4 levels. After the addition of Prx4 to the FRS, the net reclassification improvement was 2.7% (P=0.01) using 10-year risk categories of CVD. CONCLUSIONS: Elevated serum Prx4 levels are associated with a significantly higher risk of incident CVD events or CVD mortality and all-cause mortality after adjustment for clinical risk factors. The addition of Prx4 to the FRS marginally improved risk prediction of future CVD
The Spitzer Spirals, Bridges, and Tails Interacting Galaxy Survey: Interaction-Induced Star Formation in the Mid-Infrared
We present Spitzer mid-infrared imaging of a sample of 35 tidally-distorted pre-merger interacting galaxy pairs selected from the Arp Atlas. We compare their global mid-infrared properties with those of normal galaxies from the SINGS Spitzer Legacy survey, and separate the disk emission from that of the tidal features. The [8.0 micron] - [24 micron], [3.6 micron] - [24 micron], and [5.8 micron] - [8.0 micron] colors of these optically-selected interacting galaxies are redder on average than those of spirals, implying enhancements to the mass-normalized star formation rates (SFRs) of a factor of ~2. Furthermore, the 24 micron emission in the Arp galaxies is more centrally concentrated than that in the spirals, suggesting that gas is being concentrated into the inner regions and fueling central star formation. No significant differences can be discerned in the shorter wavelength Spitzer colors of the Arp galaxies compared to the spirals, thus these quantities are less sensitive to star formation enhancements. No strong trend of Spitzer color with pair separation is visible in our sample; this may be because our sample was selected to be tidally disturbed. The tidal features contribute <10% of the total Spitzer fluxes on average. The SFRs implied for the Arp galaxies by the Spitzer 24 micron luminosities are relatively modest, ~1 M(sun)/yr on average
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