921 research outputs found

    What Evidence Exists to Verify That Learning through Aviation Works?

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    Educators and advocates for change of our schools in general and to increase student performance in particular are increasingly turning to aviation education, learning through aviation, and/or aerospace education. Two major forms of learning through aviation are found. The first is simply the study of aviation for its own sake. Studying ground school and then going on to learn to fly is an example of this. A higher, more sophisticated form is that found in specialized high school and undergraduate college and university programs such as those in Aviation High School in New York or Embry Riddle Aeronautical University in Daytona Beach, Florida. The second form of learning is the central purpose of this brief paper. This paper is concerned with the uses of aviation as a central motif, core, thread, or magnet around which to design worthwhile educational programs, activities, projects, courses, and learning experiences in order to facilitate learning--learning not just aviation but also learning basic subjects which most people feel good schools should provide. For purposes of this paper, elementary and secondary education are the main examples used

    Demonstrating Universal Scaling in Quench Dynamics of a Yukawa One-Component Plasma

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    The Yukawa one-component plasma (OCP) is a paradigm model for describing plasmas that contain one component of interest and one or more other components that can be treated as a neutralizing, screening background. In appropriately scaled units, interactions are characterized entirely by a screening parameter, κ\kappa. As a result, systems of similar κ\kappa show the same dynamics, regardless of the underlying parameters (e.g., density and temperature). We demonstrate this behavior using ultracold neutral plasmas (UNP) created by photoionizing a cold (T≤10T\le10 mK) gas. The ions in UNP systems are well described by the Yukawa model, with the electrons providing the screening. Creation of the plasma through photoionization can be thought of as a rapid quench from κ0=∞\kappa_{0}=\infty to a final κ\kappa value set by the electron density and temperature. We demonstrate experimentally that the post-quench dynamics are universal in κ\kappa over a factor of 30 in density and an order of magnitude in temperature. Results are compared with molecular dynamics simulations. We also demonstrate that features of the post-quench kinetic energy evolution, such as disorder-induced heating and kinetic-energy oscillations, can be used to determine the plasma density and the electron temperature.Comment: 10 pages, 12 figures, to be submitted to Physical Review

    Ion holes in the hydrodynamic regime in ultracold neutral plasmas

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    We describe the creation of localized density perturbations, or ion holes, in an ultracold neutral plasma in the hydrodynamic regime, and show that the holes propagate at the local ion acoustic wave speed. We also observe the process of hole splitting, which results from the formation of a density depletion initially at rest in the plasma. One-dimensional, two-fluid hydrodynamic simulations describe the results well. Measurements of the ion velocity distribution also show the effects of the ion hole and confirm the hydrodynamic conditions in the plasma

    Prognostic Role of Polyvascular Involvement in Patients with Symptomatic Peripheral Artery Disease.

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    Background: Statin therapy is recommended for patients with peripheral artery disease (PAD). However, PAD patients with polyvascular (PV) extent remain threatened by an increased residual cardiovascular (CV) risk. Purpose: To investigate the association of prescribed statin therapy and mortality in PAD patients with or without PV extent. Methods: A single-center retrospective longitudinal observational study originating from a consecutive registry with 1380 symptomatic PAD patients over a mean observational time of 60 ± 32 months. The association of atherosclerotic extent and statin use (PAD, plus one additional region (CAD or CeVD, [+1 V]), +2 vascular regions (+CAD and CeVD [+2 V]) with the risk of all-cause mortality was evaluated using Cox proportional hazard models adjusted for potential confounding factors. Results: The mean age of the study's participants was 72.0 ± 11.7 years, with 36% being female. PAD patients with PV extent [+1 V] and [+2 V] were older and suffered from diabetes, hypertension, or dyslipidemia more often; they, too, had more severely impaired kidney function (all p < 0.0001) compared to patients with PAD only. PAD patients with PV [+1 V] and [+2 V] received better statin medication and reached the recommended LDL-C target compared to PAD-only patients (p < 0.001). Despite better statin treatment, the rate of all-cause mortality was higher in PV patients than in PAD-only patients (PAD only: 13%; [+1 V]: 22%; [+2 V]: 35%; p < 0.0001). Conclusion: PV patients receive better statin therapy than PAD-only patients but nevertheless still have higher mortality rates. Future studies are needed to explore whether more aggressive LDL-lowering treatment for PAD patients may be translated into better prognosis

    Thirty-five year mortality following receipt of SV40- contaminated polio vaccine during the neonatal period

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    Early poliovirus vaccines, both inactivated and live attenuated, were inadvertently contaminated with simian virus 40 (SV40), a monkey virus known to be oncogenic for newborn hamsters. Although large epidemiologic studies have not identified an elevated cancer risk in persons who received SV40-contaminated vaccines, fragments of SV40 DNA have recently been identified in certain human tumours. We report the follow-up of a cohort of 1073 persons, unique because they received SV40-contaminated poliovirus vaccines as newborns in 1961–63. A previous report of the status of these subjects as of 1977–79 identified 15 deaths, none due to cancer. The present study utilized the National Death Index to identify deaths in the cohort for the years 1979–96. Expected deaths were calculated from Cleveland area sex-, age-, race- and year-specific mortality rates. Increased mortality from all causes was not found. 4 deaths from cancer were found compared to 3.16 expected (P= 0.77). However, 2 deaths from testicular cancer occurred, compared to 0.05 expected (P= 0.002), which may be a chance finding due to multiple comparisons. There were 2 deaths due to leukaemia, a non-significant finding, and no deaths due to tumours of the types putatively associated with SV40. Although these results are, for the most part, consistent with other negative epidemiologic investigations of risks from SV40-contaminated vaccines, further study of testicular cancer may be warranted, and it will be important to continue monitoring this cohort which is now reaching middle-age. © 2001 Cancer Research Campaig

    HIV Serostatus and Tumor Differentiation Among Patients with Cervical Cancer at Bugando Medical Centre.

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    Evidence for the association between Human immunodeficiency virus infection and cervical cancer has been contrasting, with some studies reporting increased risk of cervical cancer among HIV positive women while others report no association. Similar evidence from Tanzania is scarce as HIV seroprevalence among cervical cancer patients has not been rigorously evaluated. The purpose of this study was to determine the association between HIV and tumor differentiation among patients with cervical cancer at Bugando Medical Centre and Teaching Hospital in Mwanza, North-Western Tanzania. This was a descriptive analytical study involving suspected cervical cancer patients seen at the gynaecology outpatient clinic and in the gynaecological ward from November 2010 to March 2011. A total of 91 suspected cervical cancer patients were seen during the study period and 74 patients were histologically confirmed with cervical cancer. The mean age of those confirmed of cervical cancer was 50.5 ± 12.5 years. Most patients (39 of the total 74-52.7%) were in early disease stages (stages IA-IIA). HIV infection was diagnosed in 22 (29.7%) patients. On average, HIV positive women with early cervical cancer disease had significantly more CD4+ cells than those with advanced disease (385.8 ± 170.4 95% CI 354.8-516.7 and 266.2 ± 87.5, 95% CI 213.3-319.0 respectively p = 0.042). In a binary logistic regression model, factors associated with HIV seropositivity were ever use of hormonal contraception (OR 5.79 95% CI 1.99-16.83 p = 0.001), aged over 50 years (OR 0.09 95% CI 0.02-0.36 p = 0.001), previous history of STI (OR 3.43 95% CI 1.10-10.80 p = 0.035) and multiple sexual partners OR 5.56 95% CI 1.18-26.25 p = 0.030). Of these factors, only ever use of hormonal contraception was associated with tumor cell differentiation (OR 0.16 95% CI 0.06-0.49 p = 0.001). HIV seropositivity was weakly associated with tumor cell differentiation in an unadjusted analysis (OR 0.21 95% CI 0.04-1.02 p = 0.053), but strong evidence for the association was found after adjusting for ever use of hormonal contraception with approximately six times more likelihood of HIV infection among women with poorly differentiated tumor cells compared to those with moderately and well differentiated cells (OR 5.62 95% CI 1.76-17.94 p = 0.004).\ud Results from this study setting suggest that HIV is common among cervical cancer patients and that HIV seropositivity may be associated with poor tumour differentiation. Larger studies in this and similar settings with high HIV prevalence and high burden of cervical cancer are required to document this relationship

    The Quasar SDSS J105041.35+345631.3: Black Hole Recoil or Extreme Double-Peaked Emitter?

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    The quasar SDSS J105041.35+345631.3 (z = 0.272) has broad emission lines blueshifted by 3500 km/s relative to the narrow lines and the host galaxy. Such an object may be a candidate for a recoiling supermassive black hole, binary black hole, a superposition of two objects, or an unusual geometry for the broad emission-line region. The absence of narrow lines at the broad line redshift argues against superposition. New Keck spectra of J1050+3546 place tight constraints on the binary model. The combination of large velocity shift and symmetrical H-beta profile, as well as aspects of the narrow line spectrum, make J1050+3546 an interesting candidate for black hole recoil. Other aspects of the spectrum, however, suggest that the object is most likely an extreme case of a ``double-peaked emitter.'' We discuss possible observational tests to determine the true nature of this exceptional object.Comment: 5 pages, 2 figures, LaTeX; substantial revision
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