Thermalization at intermediate coupling

We use the AdS/CFT conjecture to investigate the thermalization of large-N_c N=4 Super Yang-Mills plasma in the limit of large but finite 't Hooft coupling. On the gravity side, we supplement the type IIB supergravity action by the full set of O(\alpha'^3) operators, which enables us to derive O(\lambda^{-3/2}) corrections to the emission spectrum of prompt photons in one model of holographic thermalization. Decreasing the coupling strength from the \lambda=\infty limit, we observe a qualitative change in the way the photon spectral density approaches its thermal limit as a function of the photon energy. We interpret this behavior as a sign of the thermalization pattern of the plasma shifting from top/down towards bottom/up.Comment: 5 pages, 3 figures; v2: minor corrections, added reference

A variable neurodegenerative phenotype with polymerase gamma mutation

mtDNA replication and repair, causes mitochondrial diseases including autosomal dominant progressive external ophthalmoplegia (PEO),1 childhood hepato-encephalopathy (Alpers– Huttenlocher syndrome), adult-onset spinocerebellar ataxia, and sensory nerve degeneration with dysarthria and ophthalmoparesis (SANDO)

Pion-nucleus optical potential valid up to the DELTA-resonance region

We present in this article an optical potential for the $\pi$-nucleus interaction that can be used in various studies involving $\pi$-nucleus channels. Based on earlier treatments of the low energy $\pi$-nucleus optical potential, we have derived a potential expression applicable from threshold up to the $\Delta$-resonance region. We extracted the impulse approximation form for this potential from the $\pi-N$ scattering amplitude and then added to it kinematical and physical corrections. The kinematic corrections arise from transforming the impulse approximation expression from the $\pi-N$ center of mass frame to the $\pi$-nucleus center of mass frame, while the physical corrections arise mostly from the many-body nature of the $\pi$-nucleus interaction. By taking advantage of the experimental progress in our knowledge of the $\pi-N$ process, we have updated earlier treatments with parameters calculated from state-of-the-art experimental measurements.Comment: 23 pages, 12 figures. Accepted for publication in Physical Review

No arbitrage and closure results for trading cones with transaction costs

In this paper, we consider trading with proportional transaction costs as in Schachermayer’s paper (Schachermayer in Math. Finance 14:19–48, 2004). We give a necessary and sufficient condition for ${\mathcal{A}}$ , the cone of claims attainable from zero endowment, to be closed. Then we show how to define a revised set of trading prices in such a way that, firstly, the corresponding cone of claims attainable for zero endowment, ${\tilde{ {\mathcal{A}}}}$ , does obey the fundamental theorem of asset pricing and, secondly, if ${\tilde{ {\mathcal{A}}}}$ is arbitrage-free then it is the closure of ${\mathcal{A}}$ . We then conclude by showing how to represent claims

Maximum growth and decay rates of autotrophic biomass to simulate nitrogen removal at 10°C with municipal activated sludge plants

The present study aims at determining most likely values for the maximum growth rate (μA, max) and the endogenous decay rate (bA) of nitrifiers for activated sludge processes treating municipal wastewater operated at low temperature (10°C). The work used nitrification rate data measured on 10 full-scale plants and 2 pilot plants fed with domestic sewage. This set of data was combined with a modelling and a theoretical approach. The unified values (μA, max = 0.45·d-1 and bA = 0.13·d-1) were obtained at 10°C for the kinetic parameters of the autotrophic biomass in the SRT range 10 to 50 d. In addition, the factors affecting the expected nitrification rate (rv, nit) were established by a theoretical approach and confirmed by experimental results. For a given SRT, a linear relationship with the nitrogen volumetric loading rate was shown. The COD/TKN ratio of the influent on the nitrification rate was demonstrated. Finally, an operational tool for the verification of the nitrification rate in the design procedure of activated sludge processes is proposed.Keywords: nitrification; kinetics; low temperature; autotrophic biomass, maximum growth rate; decay rat

Progressive ataxia with oculo-palatal tremor and optic atrophy

The final publication is available at Springer via doi: 10.​1007/​s00415-013-7136-

Anoxic and aerobic values for the yield coefficient of the heterotrophic biomass: Determination at full-scale plants and consequences on simulations

The present study aims at optimising the nitrification and denitrification phases at intermittently aerated process (activated sludge) removing nitrogen from municipal wastewater. The nitrogen removal performance recorded at 22 intermittently aerated plants was compared to the results obtained from the simulations given by the widely used ASM1. It is shown that simulations with a single value for the heterotrophic yield with any electron acceptor over-predict the nitrate concentration in the effluent of treatment plants. The reduction of this coefficient by 20% for anoxic conditions reduces the nitrate concentration by 10 g N·m-3. It significantly improves the accuracy of the predictions of nitrate concentrations in treatedeffluents compare to real data. Simulations with dual values (aerobic and anoxic conditions) for heterotrophic yield (modified ASM1) were then used to determine the practical daily aerobic time interval to meet a given nitrogen discharge objective. Finally, to support design decisions, the relevance of a pre-denitrification configuration in front of an intermittently aerated tank was studied. It is shown that when the load of BOD5 is below the conventional design value, a small contribution of the anoxic zone to nitrate removal occurs, except for over-aerated plants. When plants receive a higher load of BOD5, the modified ASM1 suggests that the anoxic zone has a higher contribution to nitrogen removal, for both correctly and over-aerated plants

Diuretic Use and Serum Phosphate:Rotterdam Study and UK Biobank

Purpose: Hypophosphatemia (serum phosphate &lt; 0.80 &lt;FOR VERIFICATION&gt;mmol/L) leads to musculoskeletal complaints. The most common drugs linked to hypophosphatemia are thiazide and loop diuretics, but studies in the general population are lacking. Our aim was to study associations between diuretic use and serum phosphate in the Rotterdam Study (RS), a population-based cohort study, with replication in UK Biobank (UKBB).Methods: Associations between thiazide and loop diuretic use and serum phosphate and odds of hypophosphatemia were analyzed with cross-sectional multivariate linear and logistic regression in participants without chronic kidney disease in the RS and UKBB. Analyses were adjusted for age, sex, and body mass index (BMI) and pooled in 3 RS cohorts with further adjustment for cohort and serum potassium, which was not available in UKBB. Results: Thiazide diuretics were associated with lower serum phosphate in both sexes. This association lost significance in RS females after adjustment for BMI and in males after adjustment for serum potassium. Thiazide diuretics increased odds of hypophosphatemia in females in both cohorts and in males in UKBB only. Loop diuretics were associated with lower serum phosphate in females but not males. Adjustment for BMI attenuated these associations. Associations between loop diuretics and increased odds of hypophosphatemia in females lost significance after BMI adjustment. Conclusion: Thiazides, but not loop diuretics, and increased BMI and decreased serum potassium should be considered as contributing factors in subjects with hypophosphatemia. Further studies are needed to replicate the findings and elucidate the potential role of hypokalemia as a mediator of this effect.</p

The worrying mind in control: an investigation of adaptive working memory training and cognitive bias modification in worry-prone individuals

Worry refers to the experience of uncontrollable negative thoughts. Cognitive models suggest that the combination of negative information processing biases along with diminished attentional control contribute to worry. In the current study we investigate whether promoting a) adaptive interpretation bias and b) efficient deployment of attentional control would influence the tendency to worry. Worry-prone individuals (n = 60) received either active cognitive bias modification for interpretation bias (CBM-I) combined with sham working memory training (WMT), adaptive WMT combined with sham CBM-I, or sham WMT combined with sham CBM-I. Neither of the active training conditions reduced worry during a breathing focus task relative to the control condition. However, when considering inter-individual differences in training-related improvements, we observed a relation between increases in positive interpretation bias and a decrease in negative intrusions. Moreover, increases in working memory performance were related to a reduction in reactivity of negative intrusions to a worry period. Our findings show that facilitating a more benign interpretation bias and improving working memory capacity can have beneficial effects in terms of worry, but also highlight that transfer related gains from existing training procedures can be dependent upon improvement levels on the training task