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Anharmonic multi-phonon nonradiative transition: An ab initio calculation approach
Nonradiative carrier recombinations at deep centers in semiconductors are of great importance for both fundamental physics and device engineering. In this article, we provide a revised analysis of Huangâs original nonradiative multi-phonon (NMP) theory with ab initio calculations. First, we confirmed at the first-principles level that Huangâs concise formula gives the same results as the matrix-based formula, and that Huangâs high-temperature formula provides an analytical expression for the coupling constant in Marcus theory. Secondly, we correct for anharmonic effects by taking into account local phonon-mode variations for different charge states of a defect. The corrected capture rates for defects in GaN and SiC agree well with experiments
Flat Dielectric Grating Reflectors with High Focusing Power
Sub-wavelength dielectric gratings (SWG) have emerged recently as a promising
alternative to distributed-Bragg-reflection (DBR) dielectric stacks for
broadband, high-reflectivity filtering applications. A SWG structure composed
of a single dielectric layer with the appropriate patterning can sometimes
perform as well as thirty or forty dielectric DBR layers, while providing new
functionalities such as polarization control and near-field amplification. In
this paper, we introduce a remarkable property of grating mirrors that cannot
be realized by their DBR counterpart: we show that a non-periodic patterning of
the grating surface can give full control over the phase front of reflected
light while maintaining a high reflectivity. This new feature of dielectric
gratings could have a substantial impact on a number of applications that
depend on low-cost, compact optical components, from laser cavities to CD/DVD
read/write heads.Comment: submitted to Nature Photonic
Pilot project of integration of Chinese medicine (acupuncture) and Western medicine for neurohabilitation of children with acquired brain injury: a study of 2 cases
PURPOSE: To demonstrate if there is any efficacy of integration of Chinese medicine (acupuncture) and western medicine for rehabilitation for two children with acquired brain injury (ABI). METHODS: Two children (M/1 year, with dystonic cerebral palsy, cortical visual impairment and global developmental delay due to acute encephalitis; and M/12 years, with spastic tetraplegia, cortical visual impairment, and severe mental retardation due to hypoxic-ischaemic encephalopathy related to hypertrophic cardiomyopathy) were enrolled into our pilot programme which had started as the âFirst Integrated Chinese Medicine and Western Medicine for Neurorehabilitation of Children with Traumatic or Acquired Brain Injury under the Hospital Authorityâ in June 2008. Both of them received daily acupuncture treatment and conventional neurohabilitation programme for 4 months. Pre- and post-assessment were performed for both cases. Deoxyglucose PET scan of the brain, parental daily reports for any change after each acupuncture session were monitored. Objective outcome measures were performed by the Neurohabilitation Team with allied health disciplines including physiotherapist, occupational therapist, optometrist, audiologist, speech therapist and clinical psychologist in pre- and post-acupuncture treatment using objective outcome measures including Modified Ashworth Spasticity Scale, CVI assessment, Video Fluoroscopic Swallow Study (VFSS) and Functional Independence Measure of Children (WeeFIM). Videos were taken by blind assessors. RESULTS: PET scan of the brain showed mild-to-moderate increase in glucose uptake for both cases. Videos and clinical outcome measures showed improvement in vision and other parameters. CONCLUSIONS: A short and intensive course of acupuncture can be effective in improving visual and functional outcome for children with ABI. Further research is underway to assess the practicability of organising this model of integration of Chinese medicine (acupuncture) and western medicine for neurohabilitation of children with ABI in Hong Kong.published_or_final_versio
P2X receptors: epithelial ion channels and regulators of salt and water transport.
When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion channels, P2X receptors, play a specialized role in the regulation of ion and water movement across the renal tubule and are integral to electrolyte and fluid homeostasis. In this short review, we discuss the concept of P2X receptors as regulators of salt and water salvage pathways, as well as acknowledging their accepted role as ATP-gated ion channels
Three Courses of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinic Efficacy Observation Trail
published_or_final_versio
Serum levels of WNT1-inducible signaling pathway protein-1 (WISP-1): a noninvasive biomarker of renal fibrosis in subjects with chronic kidney disease
WNT1-inducible signaling pathway protein-1 (WISP-1) is an extracellular matrix-related protein that plays multiple roles in cellular physiology and pathology. Accumulating evidence shows that WISP-1 is involved in the process underlying fibrotic diseases. However, the correlation between WISP-1 and renal fibrosis is unknown. In this study, we hypothesized that WISP-1 levels might be correlated with renal fibrosis and could be used as a noninvasive biomarker to screen for renal fibrosis in patients with chronic kidney disease (CKD). We first measured the WISP-1 expression levels using a transforming growth factor-β (TGF-β)-induced renal fibrosis tubular epithelial cell (TEC) model and a mouse model of obstructive nephropathy. We then evaluated the correlation between serum WISP-1 levels and fibrosis scores in biopsy-proven renal fibrosis of patients with CKD. Based on the findings from both in vivo and in vitro studies, the levels of WISP-1 and fibrotic parameters (collagen I, fibronectin and ι-smooth muscle actin) were significantly increased in the fibrotic models. Consistently, patients with focal proliferative IgA nephropathy, focal segmental glomerular sclerosis and diabetic nephropathy displayed markedly elevated serum WISP-1 levels and fibrosis scores of renal biopsies compared with normal subjects and patients with minimal change disease (P<0.05). Importantly, the serum WISP-1 levels were positively correlated with fibrosis scores in the renal biopsies of these patients (r=0.475, P=0.0001). Thus, serum WISP-1 levels may be used as a potential noninvasive biomarker of renal fibrosis in patients with CKD.published_or_final_versio
Improved harmony search methods to replace variational principle in geotechnical problems
2010-2011 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Effects of hydrogen bond and solvent polarity on the C=O strectching of bis(2-thienyl)ketone in solution
The optimized structural parameters, the absorption and the resonance Raman spectra have been investigated for the bis(2-thienyl)ketone in gas phase, in cyclohexane, methanol, and acetonitrile solvents by means of time dependent density functional theory calculations, the solvent electronic polarization effect on the solvation shift is examined and in well accordance with the calculation. The effect of increasing the polarity of the solvent is well represented by the polarizable continuum model, both for the absorption spectra and resonance Raman intensities. The Raman spectra of the C=O stretching mode, which is sensitive to the intermolecular interaction for bis(2-thienyl)ketone dissolved in solvents, were systematically studied. It was found that the hydrogen bond effect plays an important role in reducing the carbonyl stretching wavenumbers. The results of Raman shifts were interpreted through the dilution effect, solvation effects, and hydrogen bond-forming effects. Furthermore, the excitation profiles of several important Raman bands of bis(2-thienyl)ketone molecule in different solvents have been critically analyzed. The solvent effects on structural and symmetry properties of the molecule in S2 electronic state as well as the short-time photo relaxation dynamics have been discussed.published_or_final_versio
Nonlinear frequency mixing in quantum cascade lasers: Towards broadband wavelength shifting and THz up-conversion
Terahertz (THz) sideband generation on a near-infrared (NIR) carrier has been recently demonstrated using quantum cascade lasers (QCL), with potential applications in wavelength shifting and THz up-conversion. However, the NIR wavelength range and nonlinear efficiency were severely limited by absorption. Here we overcome this drawback through a novel reflection geometry, whilst preserving a large interaction area. As well as insights into the nonlinear mechanism, this allows a much large range of NIR pump energies, relaxing the criteria of using particular excitation wavelengths
Holographic Entanglement Entropy in P-wave Superconductor Phase Transition
We investigate the behavior of entanglement entropy across the holographic
p-wave superconductor phase transition in an Einstein-Yang-Mills theory with a
negative cosmological constant. The holographic entanglement entropy is
calculated for a strip geometry at AdS boundary. It is found that the
entanglement entropy undergoes a dramatic change as we tune the ratio of the
gravitational constant to the Yang-Mills coupling, and that the entanglement
entropy does behave as the thermal entropy of the background black holes. That
is, the entanglement entropy will show the feature of the second order or first
order phase transition when the ratio is changed. It indicates that the
entanglement entropy is a good probe to investigate the properties of the
holographic phase transition.Comment: 19 pages,15 figures, extended discussion in Sec.5, references adde
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