1,112 research outputs found
The age-metallicity structure of the Milky Way disc using APOGEE
The measurement of the structure of stellar populations in the Milky Way disc places fundamental constraints on models of galaxy formation and evolution. Previously, the disc’s structure has been studied in terms of populations defined geometrically and/or chemically, but a decomposition based on stellar ages provides a more direct connection to the history of the disc, and stronger constraint on theory. Here, we use positions, abundances and ages for 31 244 red giant branch stars from the Sloan Digital Sky Survey (SDSS)-APOGEE survey, spanning 3 < Rgc < 15 kpc, to dissect the disc into mono-age and mono-[Fe/H] populations at low and high [α/Fe]. For each population, with age < 2 Gyr and [Fe/H] < 0.1 dex, we measure the structure and surface-mass density contribution. We find that low [α/Fe] mono-age populations are fit well by a broken exponential, which increases to a peak radius and decreases thereafter. We show that this profile becomes broader with age, interpreted here as a new signal of disc heating and radial migration. High [α/Fe] populations are well fit as single exponentials within the radial range considered, with an average scalelength of 1.9 ± 0.1 kpc. We find that the relative contribution of high to low [α/Fe] populations at R0 is f� = 18 per cent ± 5 per cent; high [α/Fe] contributes most of the mass at old ages, and low [α/Fe] at young ages. The low and high [α/Fe] populations overlap in age at intermediate [Fe/H], although both contribute mass at R0 across the full range of [Fe/H]. The mass-weighted scaleheight hZ distribution is a smoothly declining exponential function. High [α/Fe] populations are thicker than low [α/Fe], and the average hZ increases steadily with age, between 200 and 600 pc
Measuring Black Hole Formations by Entanglement Entropy via Coarse-Graining
We argue that the entanglement entropy offers us a useful coarse-grained
entropy in time-dependent AdS/CFT. We show that the total von-Neumann entropy
remains vanishing even when a black hole is created in a gravity dual, being
consistent with the fact that its corresponding CFT is described by a
time-dependent pure state. We analytically calculate the time evolution of
entanglement entropy for a free Dirac fermion on a circle following a quantum
quench. This is interpreted as a toy holographic dual of black hole creations
and annihilations. It is manifestly free from the black hole information
problem.Comment: 25 pages, Latex, 8 figure
Intertwining Relations for the Deformed D1D5 CFT
The Higgs branch of the D1D5 system flows in the infrared to a
two-dimensional N=(4,4) SCFT. This system is believed to have an "orbifold
point" in its moduli space where the SCFT is a free sigma model with target
space the symmetric product of copies of four-tori; however, at the orbifold
point gravity is strongly coupled and to reach the supergravity point one needs
to turn on the four exactly marginal deformations corresponding to the blow-up
modes of the orbifold SCFT. Recently, technology has been developed for
studying these deformations and perturbing the D1D5 CFT off its orbifold point.
We present a new method for computing the general effect of a single
application of the deformation operators. The method takes the form of
intertwining relations that map operators in the untwisted sector before
application of the deformation operator to operators in the 2-twisted sector
after the application of the deformation operator. This method is
computationally more direct, and may be of theoretical interest. This line of
inquiry should ultimately have relevance for black hole physics.Comment: latex, 23 pages, 3 figure
An area law for entanglement from exponential decay of correlations
Area laws for entanglement in quantum many-body systems give useful
information about their low-temperature behaviour and are tightly connected to
the possibility of good numerical simulations. An intuition from quantum
many-body physics suggests that an area law should hold whenever there is
exponential decay of correlations in the system, a property found, for
instance, in non-critical phases of matter. However, the existence of quantum
data-hiding state--that is, states having very small correlations, yet a volume
scaling of entanglement--was believed to be a serious obstruction to such an
implication. Here we prove that notwithstanding the phenomenon of data hiding,
one-dimensional quantum many-body states satisfying exponential decay of
correlations always fulfil an area law. To obtain this result we combine
several recent advances in quantum information theory, thus showing the
usefulness of the field for addressing problems in other areas of physics.Comment: 8 pages, 3 figures. Short version of arXiv:1206.2947 Nature Physics
(2013
Evaluating applicants to a new emergency medicine residency program: subjective assessment of applicant characteristics
Estimating stellar birth radii and the time evolution of the Milky Way's ISM metallicity gradient
We present a semi-empirical, largely model-independent approach for estimating Galactic birth radii, r_birth, for Milky Way disk stars. The technique relies on the justifiable assumption that a negative radial metallicity gradient in the interstellar medium (ISM) existed for most of the disk lifetime. Stars are projected back to their birth positions according to the observationally derived age and [Fe/H] with no kinematical information required. Applying our approach to the AMBRE:HARPS and HARPS-GTO local samples, we show that we can constrain the ISM metallicity evolution with Galactic radius and cosmic time, [Fe/H]_ISM(r, t), by requiring a physically meaningful r_birth distribution. We find that the data are consistent with an ISM radial metallicity gradient that flattens with time from ~-0.15 dex/kpc at the beginning of disk formation, to its measured present-day value (-0.07 dex/kpc). We present several chemo-kinematical relations in terms of mono-r_birth populations. One remarkable result is that the kinematically hottest stars would have been born locally or in the outer disk, consistent with thick disk formation from the nested flares of mono-age populations and predictions from cosmological simulations. This phenomenon can be also seen in the observed age-velocity dispersion relation, in that its upper boundary is dominated by stars born at larger radii. We also find that the flatness of the local age-metallicity relation (AMR) is the result of the superposition of the AMRs of mono-r_birth populations, each with a well-defined negative slope. The solar birth radius is estimated to be 7.3+-0.6 kpc, for a current Galactocentric radius of 8 kpc
Role of anesthesiology curriculum in improving bag-mask ventilation and intubation success rates of emergency medicine residents: a prospective descriptive study
<p>Abstract</p> <p>Background</p> <p>Rapid and safe airway management has always been of paramount importance in successful management of critically ill and injured patients in the emergency department. The purpose of our study was to determine success rates of bag-mask ventilation and tracheal intubation performed by emergency medicine residents before and after completing their anesthesiology curriculum.</p> <p>Methods</p> <p>A prospective descriptive study was conducted at Nikoukari Hospital, a teaching hospital located in Tabriz, Iran. In a skills lab, a total number of 18 emergency medicine residents (post graduate year 1) were given traditional intubation and bag-mask ventilation instructions in a 36 hour course combined with mannequin practice. Later the residents were given the opportunity of receiving training on airway management in an operating room for a period of one month which was considered as an additional training program added to their Anesthesiology Curriculum. Residents were asked to ventilate and intubate 18 patients (Mallampati class I and ASA class I and II) in the operating room; both before and after completing this additional training program. Intubation achieved at first attempt within 20 seconds was considered successful. Successful bag-mask ventilation was defined as increase in ETCo<sub>2 </sub>to 20 mm Hg and back to baseline with a 3 L/min fresh gas-flow and the adjustable pressure limiting valve at 20 cm H<sub>2</sub>O. An attending anesthesiologist who was always present in the operating room during the induction of anesthesia confirmed the endotracheal intubation by direct laryngoscopy and capnography. Success rates were recorded and compared using McNemar, marginal homogeneity and paired t-Test tests in SPSS 15 software.</p> <p>Results</p> <p>Before the additional training program in the operating room, the participants had intubation and bag-mask ventilation success rates of 27.7% (CI 0.07-0.49) and 16.6% (CI 0-0.34) respectively. After the additional training program in the operating room the success rates increased to 83.3% (CI 0.66-1) and 88.8% (CI 0.73-1), respectively. The differences in success rates were statistically significant (P = 0.002 and P = 0.0004, respectively).</p> <p>Conclusions</p> <p>The success rate of emergency medicine residents in airway management improved significantly after completing anesthesiology rotation. Anesthesiology rotations should be considered as an essential component of emergency medicine training programs. A collateral curriculum of this nature should also focus on the acquisition of skills in airway management.</p
Turnip yellow mosaic virus in Chinese cabbage in Spain: Commercial seed transmission and molecular characterization
[EN] Seed transmission of Turnip yellow mosaic virus (TYMV, genus Tymovirus) was evaluated in the whole seeds and seedlings that emerged from three commercial Chinese cabbage (Brassica pekinensis) seed batches. Seedlings in the cotyledon stage and adult plants were assayed for TYMV by DAS-ELISA and confirmed by RT-PCR. The proportion of whole seeds infected with TYMV was at least 0.15 %. The seeds of the three seed batches were grown in Petri dishes, and surveyed in the cotyledon stage in trays that contained a peat:sand mixture grown in greenhouses or growth chambers, which were analysed in the cotyledon and adult stages. The seed-to-seedling transmission rate ranged from 2.5 % to 2.9 % in two different seed batches (lot-08 and lot-09, respectively). Spanish isolates derived from turnip (Sp-03) and Chinese cabbage (Sp-09 and Sp-13), collected in 2003, 2009 and 2013 in two different Spanish regions, were molecularly characterised by analysing the partial nucleotide sequences of three TYMV genome regions: partial RNA-dependent RNA polymerase (RdRp), methyltransferase (MTR) and coat protein (CP) genes. Phylogenetic analyses showed that the CP gene represented two different groups: TYMV-1 and TYMV-2. The first was subdivided into three subclades: European, Australian and Japanese. Spanish isolate Sp-03 clustered together with European TYMV group, whereas Sp-09 and Sp-13 grouped with the Japanese TYMV group, and all differed from group TYMV-2. The sequences of the three different genomic regions examined clustered into the same groups. The results suggested that Spanish isolates grouped according to the original hosts from which they were isolated. 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Towards the fast scrambling conjecture
Many proposed quantum mechanical models of black holes include highly
nonlocal interactions. The time required for thermalization to occur in such
models should reflect the relaxation times associated with classical black
holes in general relativity. Moreover, the time required for a particularly
strong form of thermalization to occur, sometimes known as scrambling,
determines the time scale on which black holes should start to release
information. It has been conjectured that black holes scramble in a time
logarithmic in their entropy, and that no system in nature can scramble faster.
In this article, we address the conjecture from two directions. First, we
exhibit two examples of systems that do indeed scramble in logarithmic time:
Brownian quantum circuits and the antiferromagnetic Ising model on a sparse
random graph. Unfortunately, both fail to be truly ideal fast scramblers for
reasons we discuss. Second, we use Lieb-Robinson techniques to prove a
logarithmic lower bound on the scrambling time of systems with finite norm
terms in their Hamiltonian. The bound holds in spite of any nonlocal structure
in the Hamiltonian, which might permit every degree of freedom to interact
directly with every other one.Comment: 34 pages. v2: typo correcte
Inhibition of sialidase activity and cellular invasion by the bacterial vaginosis pathogen Gardnerella vaginalis
Bacterial vaginosis is a genital tract infection, thought to be caused by transformation of a lactobacillus-rich flora to a dysbiotic microbiota enriched in mixed anaerobes. The most prominent of these is Gardnerella vaginalis (GV), an anaerobic pathogen that produces sialidase enzyme to cleave terminal sialic acid residues from human glycans. Notably, high sialidase activity is associated with preterm birth and low birthweight. We explored the potential of the sialidase inhibitor Zanamavir against GV whole cell sialidase activity using methyl-umbelliferyl neuraminic acid (MU-NANA) cleavage assays, with Zanamavir causing a 30% reduction in whole cell GV sialidase activity (p < 0.05). Furthermore, cellular invasion assays using HeLa cervical epithelial cells, infected with GV, demonstrated that Zanamivir elicited a 50% reduction in cell association and invasion (p < 0.05). Our data thus highlight that pharmacological sialidase inhibitors are able to modify BV-associated sialidase activity and influence host-pathogen interactions and may represent novel therapeutic adjuncts
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