The social self-efficacy of students: a research school of Physical Education and sports at Anadolu University

The social self-efficacy of students: a research school of physical education and sports at Anadolu University. The aim of this study was to investigate social self-efficacy perception of Physical Education and Sports School students at Anadolu University in terms of gender, departments and ages. 274 Anadolu University Physical Education and Sports School students were formed the research universe. Data were collected by means of “Social Self-efficacy Scale” which was originally developed by Smith-Betz (2000) and reorganized by Palancı (2004) in Turkey. The survey consists of two parts. In the first section contains demographic factors. Second part of the questionnaire is to determine social self-efficacy perception of students in the School of Physical Education and Sports at Anadolu University and consisted of 25 items. In the data analysis, “arithmetic mean and standard deviation” for numerical comparisons were used. In order to determine the differences among attitudes, t-test was used for two-way comparisons for independent groups and ANOVA was used in order to compare variables of groups more than two. In the statistical analysis, 0.05 was accepted as the significance level. The results of the analyses indicated that the social self-efficacy perception of students use differentiated according to gender and departments, but didn’t differentiate according to ages

The metacognition levels of students: a research school of physical education and sports at Anadolu University

The aim of this research was to find out the perceived metacognition level of Physical Education and Sports School students at Anadolu University and to identify whether metacognition levels display significant differences in terms of various variables. The subject population sample was 416 Anadolu University Physical Education and Sports School students. "The Meta-Cognitions Questionnaire (MCQ-30)" developed by Cartwright-Hatton and Wells and later developed the 30-item short form (MCQ-30) was used. The MCQ-30 which was adapted into Turkish by Tosun and Irak is a four point agreement scale (Tosun & Irak, 2007). Each item in this scale is analyzed separately ranging from "(1) strongly disagree" to "(4) strongly agree.” In the data analysis, “arithmetic mean, standard deviation, t-test and ANOVA” were used. As a result of this study there was no significant difference between their genders for uncontrollableness and danger, cognitive awareness, cognitive confidence and the positive beliefs. On the other hand there is significant difference between their genders for need to control thinking. (p<0.05). Yılmaz (2007) and Semerci & Elaldı’s (2011) findings corresponded to the results of this research. There is no significant difference between their departments for uncontrollableness and danger, cognitive awareness, cognitive confidence, need to control thinking and the positive beliefs. There was no significant difference between their class levels for the positive beliefs, cognitive confidence and need to control thinking. On the other hand, there was significant difference between their class levels for uncontrollableness and danger and cognitive awareness (p<0.05). The result of this study is supported with literature (Demir & Özmen, 2011)

Romatoid Artritli Hastalarda Serum Tümör Belirteçleri Düzeyleri

Giriş ve Amaç: Romatoid Artrit (RA) eklemleri etkileyen ve görece sık rastlanılan inflamatuar bir hastalıktır. Bu çalışmada RA tanılı hastalarda serum tümör belirteçleri olan karsinoembriyonik antijeni (CEA) ,CA 125, CA 19.9 ve CA15.3 düzeylerinin belirlenmesi amaçlanmıştır Yöntem: Bir üniversite hastanesinin romatoloji kliniğinde RA tanısı ile takip edilmekte olan toplam 148 hasta çalışma grubuna ve osteoartrit tanılı 36 hasta ise kontrol grubuna dâhil edilmiştir. Çalışmaya katılan bireylerden alınan kan örneklerinden romatoid faktör (RF), eritrosit sedimantasyon hızı (ESR), anti siklik sitrilünepeptid (anti CCP) ve serum tümör belirteçleri olan CEA,CA19.9,CA 125 ve CA 15.3 düzeyleri ölçülmüştür. Hastalık aktivite skoru çalışmaya dâhil edilme sırasında ilgili romatoloji uzmanı tarafından değerlendirilmiştir. Bulgular: Serum CEA,CA19.9,CA 125 ve CA15.3 düzeyleri RA tanılı hastalarda kontrollere göre anlamlı olarak daha yüksek saptanmıştır. Hem aktif hem de inaktif hasta grubunda tümör belirteç düzeyleri kontrol grubuna göre anlamlı olarak yüksek ölçülmüştür ancak tümör belirteçleri ile hastalık aktivite skoru arasında bir korelasyon saptanamamıştır. Tümör belirteçleri arasında yalnızca CEA ile RF arasında bir korelasyon saptanmıştır(r 0.165, p >0.049). Tartışma ve Sonuç: Serum tümör belirteçleri RA tanılı hastalarda sıklıkla yüksek seviyelerde saptanabilir. Hastaların takibinden sorumlu olan hekimlerin bu durumdan haberdar olmaları, bu hasta grubunda malignite varlığı araştırma amacı ile yapılabilecek olan gereksiz işlemlerin önüne geçilmesine yardımcı olacaktır.Introduction: Rheumatoid arthritis (RA) is a relatively common inflammatory disease generally affecting the joints. This study aimed to assess the levels of various serum tumors markers; carcinoembryonic antigen (CEA), CA 125, CA 19.9 and CA15.3 in patients with a known diagnosis of RA. Methods: A total of 148 patients who were being followed in the rheumatology clinic of a tertiary academic center with a diagnosis of RA and 36 controls were included in the study group. Measurement of rheumatoid factor (RF), erythrocyte sedimentation rate (ESR), anti CCP and serum tumor markers including CEA, CA 19.9, CA 125, CA 15.3 were made from the blood samples obtained from the participants. Disease activity score at the time of study entry was also evaluated by the attending rheumatologist. Results: Serum levels of CEA, CA19.9, CA 125 and CA 15.3 were found to be significantly higher in RA patients compared to controls. This difference was statistically significant in both patient groups with active and inactive disease compared to the control group. However a correlation between tumor markers and disease activity score was not found. Among tumor markers only serum CEA levels were found to be associated with RF levels (r 0.165, p &gt;0.049) Discussion and Conclusion: Serum tumor markers are frequently elevated in patients with RA and caring physicians should be aware of this phenomenon to avoid the use of unnecessary evaluative procedures for searching presence of malignancy in these group of patients

Frequency of latent tuberculosis in patients receiving Anti-TNF-Alpha therapy

Setting-Objective: In this study, it was aimed to reveal the incidence of tuberculosis development in patients receiving tumor necrosis factor-alpha (TNF-α) blocker therapy, despite tuberculosis chemoprophylaxis. Design: 520 patients who were receiving anti TNF-α treatment in the last 3 years were evaluated retrospectively. Radiological imaging tuberculin skin test (TST), history of tuberculosis, BCG vaccine, chemoprophylaxis administration, used anti TNF-α drugs were recorded. Results: There were 265(51.0%) of the patients with ankylosing spondylitis (AS), 175(33.7%) with rheumatoid arthritis, 35(6.7%) with Crohn's, 10(1.9%) with ulcerative colitis (UC), 21(4.0%) with psoriatic arthritis, 14(2.7%) with psoriasis vulgaris. In total, 455 (79.6%) patients were given INH prophylaxis. Active tuberculosis development was observed in five patients (4: pulmonary,1: extrapulmonary; 3: UC, 2:AS) who all received anti TNF-α treatment (0.96%), infliximab. Three patients had tuberculosis disease in the 6th month, and the other 2 patients in the 5th and 24th month of their anti TNF-α treatments, and two had 9-month, and 1 had 6-month chemoprophylaxis history. Conclusion: The incidence of tuberculosis development in patients treated with anti TNF-α was found to be higher than the general population. In our country, where tuberculosis is still prevalent, patients receiving Anti TNF-α treatment (especially in-fliximab) should be carefully questioned and examined about tuberculosis

The Prevelance of Irritable Bowel Syndrome in Patients with Ankylosing Spondylitis

ÖzAmaç: İrritabl barsak sendromu (İBS), barsak alışkanlıklarında değişim ve kronik karın ağrısı ile karakterize bağırsağın fonksiyonel birhastalığıdır. İBS’ nin Romatoid artrit (RA) gibi inflamatuar patolojilerle artmış birlikteliğine rağmen, patofizyolojisinde inflamasyonun rolünetleştirilebilmiş değildir. Ankilozan Spondilit (AS) başlıca aksiyel iskelet sistemini tutan, kronik inflamatuvar bir hastalıkdır. Çalışmamızınamacı AS’ de İBS sıklığını tespit etmek ve bunun başta hastalık aktivitesi olmak üzere diğer faktörlerle ilişkisini ortaya koymaktır.Materyal ve Metot: Çalışmaya Namık Kemal Üniversitesi romatoloji kliniğindeki 145 AS tanılı hasta dahil edildi. Hastaların demografik,klinik ve laboratuvar verileri ile birlikte hastalık aktivitesi ve biyolojik ilaç kullanımı kaydedildi. ROMA III kriterlerine göre İBS tanısı ve tipiincelendi.Bulgular: AS hastalarındaki İBS sıklığı %31.7 idi. İBS sıklığı hastalık aktivitesi yüksek olan (BASDAI>4) ve biyolojik ajan tedavisialanlarda anlamlı şekilde yüksekti (p4) and in patients treated with biological agents (p values <0.001, 0.010, respectively). IBS was significantly higher in female patients by gender and young patients (<50) by age (p: 0.012 and p: 0.01 respectively). Conclusion: IBS, when compared to the normal population, was found to be higher (%31,7) in patients with AS. The relationship between AS disease activity score and IBS suggests the effect of inflammation in pathogenesis. As a result, in patients with AS, especially with high disease activity, gastroenterological complaints should be questioned; and IBS as frequent comorbidity, shouldn’t be ignored in the follow-u

Sex Estimation From Sternal Measurements Using Multidetector Computed Tomography

We aimed to show the utility and reliability of sternal morphometric analysis for sex estimation. Sex estimation is a very important step in forensic identification. Skeletal surveys are main methods for sex estimation studies. Morphometric analysis of sternum may provide high accuracy rated data in sex discrimination. In this study, morphometric analysis of sternum was evaluated in 1mm chest computed tomography scans for sex estimation. Four hundred forty 3 subjects (202 female, 241 male, mean age: 44 +/- 8.1 [ distribution: 30-60 year old]) were included the study. Manubrium length (ML), mesosternum length (2L), Sternebra 1 (S1W), and Sternebra 3 (S3W) width were measured and also sternal index (SI) was calculated. Differences between genders were evaluated by student t-test. Predictive factors of sex were determined by discrimination analysis and receiver operating characteristic (ROC) analysis. Male sternalmeasurement values are significantly higher than females (P< 0.001) while SI is significantly low in males (P< 0.001). In discrimination analysis, MSL has high accuracy rate with 80.2% in females and 80.9% in males. MSL also has the best sensitivity (75.9%) and specificity (87.6%) values. Accuracy rates were above 80% in 3 stepwise discrimination analysis for both sexes. Stepwise 1(ML, MSL, S1W, S3W) has the highest accuracy rate in stepwise discrimination analysis with 86.1% in females and 83.8% in males. Our study showed that morphometric computed tomography analysis of sternum might provide important information for sex estimation

Contribution of Leukocyte Platelet Aggregates To Development of Thrombosis In Patients With Advanced Cancer

Objective:The aim of our study was to determine the correlation between leukocyte platelet aggregates and thrombosis in patients with solid tumors who are susceptible to inflammation and thrombosis.Material and Method:In this study, we compared laboratory and clinical data of 28 metastatic gastrointestinal tumors, 33 metastatic lung tumors, 29 operated tumor patients, for a total of 90 patients with a control group consisting of 12 healthy volunteers followed at Namik Kemal University Oncology clinic in between 2013 -2014.Results:According to the results, monocyte platelet aggregates level of metastatic gastrointestinal tumors and operated tumors were found to be significantly higher compared to the control group (p: 0.05, 0.029, respectively. No significant difference was observed between the groups in the levels of thrombin-antithrombin III complex and neutrophil lymphocyte ratio. When all groups were analyzed to assess the hypercoagulopathy, deep vein thrombosis frequency were identified as 22% (18 patients). The rate was 17% in operated tumors, and was 21% in metastatic lung tumors. The incidence of deep vein thrombosis in metastatic gastrointestinal tumors was found to be 35%. There was no significant difference between patients with and without deep vein thrombosis about age, monocyte platelet aggregates, granulocyte platelet aggregates, thrombin-antithrombin III complex and high-sensitivity C-reactive protein levels.Conclusion:In conclusion, to the best of our knowledge for the first time we found leukocyte platelet aggregate values increases in cancer patients of different stages and different tissue origin. To confirm the results we have achieved, and to demonstrate the potential impact of this information in estimation of thrombotic events in cancer patients more studies conducted in larger groups of patients are needed

Fetuin-A is related to syndesmophytes in patients with ankylosing spondylitis: a case control study

OBJECTIVES: New bone formation is one of the hallmark characteristics of ankylosing spondylitis, which is thereby associated with syndesmophytes. Fetuin-A is a molecule that is abundantly found in calcified tissues and it shows high affinity for calcium phosphate minerals and related compounds. Considering the role of fetuin-A in the regulation of calcified matrix metabolism, we compared the fetuin-A levels in ankylosing spondylitis patients with syndesmophytes with those in patients without syndesmophytes and in healthy controls. We also studied other biomarkers that are thought to be related to syndesmophytes. METHODS: Ninety-four patients (49 patients without syndesmophytes, 67.3% male, 40.7±8.7 years; 45 patients with syndesmophytes, 71.1% M, 43.9±9.9 years) and 68 healthy controls (44.2±10.6 years and 70.6% male) were included in this study. Syndesmophytes were assessed on the lateral radiographs of the cervical and lumbar spine. The serum levels of fetuin-A, dickkopf-1, sclerostin, IL-6, high-sensitivity C-reactive protein and bone morphogenetic protein-7 were measured with an enzyme-linked immunosorbent assay. RESULTS: Patients with syndesmophytes had significantly higher levels of fetuin-A compared with patients without syndesmophytes and controls (1.16±0.13, 1.05±0.09 and 1.08±0.13 mg/ml, respectively). However, fetuin-A was not different between the patients without syndesmophytes and controls. Bone morphogenetic protein-7 was significantly lower; dickkopf-1 was significantly higher in patients with ankylosing spondylitis compared with controls. The sclerostin concentrations were not different between the groups. In regression analysis, fetuin-A was an independent, significant predictor of syndesmophytes. CONCLUSION: Our results suggest that fetuin-A may a role in the pathogenesis of bony proliferation in ankylosing spondylitis

Alopesi areata hastalarında nötrofil/lenfosit oranının ve diğer inflamatuar parametrelerin normal popülasyon ile karşılaştırılması

Amaç: Bu çalışmanın amacı; alopesi areata(AA) hastalarında nötrofil/lenfosit oranını (NLR), Eritrosit sedimentasyon hızı(ESR), C reaktif protein(CRP) gibi inflamatuar parametreleri normal populasyon ile kıyaslayarak bu parametrelerin AA hastalarında inflamasyonun şiddetini ölçebilecek bir marker olarak kullanılabilirliğini değerlendirmektir.Yöntem: Çalışmaya klinik olarak AA tanısı konmuş 234 hasta dahil edildi. 37 sağlıklı kişi alındı. Hasta dosyalarından lökosit, nötrofil ve lenfosit sayıları ile ESR ve CRP sonuçları kaydedildi. NLR ise hesaplanarak bulunup kaydedilmiştir. Bulgular: Hasta ve kontrol grubu arasında Lökosit, Nötrofil, ,Hb ve Esr değerleri ile NLR açısından anlamlı fark saptanmazken(p>0.05) Lenfosit sayıları(p=0,02) ve Crp( P <0.001) değeri AA hastalarında yüksek olduğu tesbit edilmiştir. Sonuç: Sonuç olarak AA hastalığında NLR değerinin kullanılabilecek bir belirteç olmadığı kanaatine varılmıştır. CRP'nin AA için kullanılabilir bir marker olduğunu gösterebilmek için daha geniş ölçekli çalışmalar yapmak gereklidir.Objective: The objective of this study is to calculate the neutrophil-lymphocyte ratio (NLR) and other inflamatory paramaters like erythrocyte sedimentation rate (ECR) and C-reactive protein results (CRP) in Alopecia areata(AA) patients and determine the association between thoose laboratory values and AA.Method: 234 patients with AA and 37 healthy subjects were enrolled in the study. Number of neutrophil, lymphocyte, leucocyte, ESR and CRP were ascertained from patient's medical records. NLR was calculated and recorded.Results: While the difference between patient and control groups in terms of value of Neutrophils, Leukocytes, Hb and Esr were found to be insignificant (p&gt;0.05), numbers of Lymphocyte (p=0,02) and value of Crp ( P &lt;0.001) in patients were found to be higher than those of healthy controls.Conclusion: This study demonstrates that NLR can not serve as a usuful marker for AA. And, as for CRP, larger-scale studies need to be done in order to demonstrate if it can serve as a marker or not

Can The Neutrophil/Leukocyte Ratio Be Used As An Acute Phase Reactant In Patients Diagnosed With Recurrent Aphthous Stomatitis?

Aim:Systemic inflammatory response can be detected using several laboratory methods, such as C-reactive protein (CRP). The purpose of this study was to assess inflammation using widely used and more easily available blood count parameters. The purpose of this study was to show changes in hematological and biochemical laboratory characteristics in recurrent aphthous stomatitis (RAS), and to assess the practicability of the neutrophil/lymphocyte ratio (NLR) as an acute phase reactant like CRP, in patients diagnosed with RAS.Materials and Methods:265 patients with a clinical diagnosis of RAS at the Namık Kemal University Research and Practice Center Dermatological and Venereal Diseases Clinic in 2010-2015 were included in the study following a retrospective review of the patient files. A control group of 299 healthy individuals was also established. Hemoglobin, leukocyte, neutrophil and lymphocyte values were recorded from the patient files, and the neutrophil/leukocyte ratio (NLR) was calculated.Results:No significant difference was determined in leukocyte, neutrophil, lymphocyte or NLR values between the RAS and control groups (p>0.05), while significant differences were observed in terms of CRP and sedimentation values (p<0.01).Conclusion:NLR cannot be used like CRP as an inflammation marker in RAS patients. New studies investigating biological markers capable of supporting clinical diagnosis and follow-up in these patients are required