424 research outputs found
Itinerant magnetism in metallic CuFe2Ge2
Theoretical calculations are performed to understand the electronic structure
and magnetic properties of CuFeGe. The band structure reveal large
electron density at the Fermi level suggesting strong itinerant
character of magnetism. The Fermi surface is dominated by two dimensional sheet
like structures, with potentially strong nesting between them. The magnetic
ground state appears to be ferromagnetic along and antiferromagnetic in
other directions. The results show that CuFeGe is an antiferromagnetic
metal, with similarities to the Fe-based superconductors; such as magnetism
with substantial itinerant character and coupling between magnetic order and
electrons at the Fermi energy.Comment: 5 pages, 6 figure
High efficient catalytic degradation of tetracycline and ibuprofen using visible light driven novel Cu/Bi2Ti2O7/rGO nanocomposite::Kinetics, intermediates and mechanism
Magnetic properties of Mn-doped Ge46 and Ba8Ge46 clathrates
We present a detailed study of the magnetic properties of unique cluster
assembled solids namely Mn doped Ge46 and Ba8Ge46 clathrates using density
functional theory. We find that ferromagnetic (FM) ground states may be
realized in both the compounds when doped with Mn. In Mn2Ge44, ferromagnetism
is driven by hybridization induced negative exchange splitting, a generic
mechanism operating in many diluted magnetic semiconductors. However, for
Mn-doped Ba8Ge46 clathrates incorporation of conduction electrons via Ba
encapsulation results in RKKY-like magnetic interactions between the Mn ions.
We show that our results are consistent with the major experimental
observations for this system.Comment: 6 pages, 4 figure
Outcome of immediate postpartum intrauterine contraceptive device in caesarean versus vaginal insertion: a comparative study
Background: Immediate Postpartum Intrauterine Contraceptive device is a novel approach to contraception which integrates Maternal - Child health and family planning services. It is a postpartum method which provides long term reversible contraception to women before discharge from the delivery setting. More research is needed in the field of PPIUCD to enhance awareness and acceptance in the community. This study is designed to compare the safety and efficacy of PPIUCD inserted at cesarean versus vaginal delivery.Methods: This is a prospective study conducted at Sree Avittom Thirunal Hospital, Govt. Medical College, and Kerala – A tertiary care teaching institution. A total of 126 patients with cesarean or vaginal deliveries had PPIUCD insertions and they were followed up for a period of one year. The outcome measures analyzed were safety measures – menstrual irregularities, vaginal discharge, pelvic infection and perforation and efficacy measures - failure, expulsion and removal. Data are expressed in frequency and percentage. Chi square test was used for comparison and P value <0.05 was considered significant.Results: The study shows that PPIUCD is an effective intervention in both cesarean and vaginal delivery with no significant differences in safety and efficacy depending on the route of insertion. There was no case of perforation or failure and no significant risk of infection in either group. Spontaneous expulsion occurred in two cases inserted by vaginal route. Missing string incidence is high in the cesarean group compared to vaginal insertion.Conclusions: PPIUCD is a safe effective and convenient method of contraception and should be encouraged in both vaginal and cesarean deliveries
A Novel Approach for Compressing Surveillance System Videos
The surveillance systems are expected to record the videos in 24/7 and obviously it requires a huge storage space. Even though the hard disks are cheaper today, the number of CCTV cameras is also vertically increasing in order to boost up security. The video compression techniques is the only better option to reduce required the storage space; however, the existing video compression techniques are not adequate at all for the modern digital surveillance system monitoring as they require huge video streams. In this paper, a novel video compression technique is presented with a critical analysis of the experimental results
Evaluvation of Anti-Oxidant and Anti Ulcer Activities of Ethanolic Extract of Desmostachya Bipinnata by Using Invivo and Invitro Methods
INTRODUCTION: Peptic Ulcer: Peptic ulcer and other acidic symptom affect up to ten percentages of the
humans with sufficient severity to prompt victims to seek medical attention.
The more significant disease condition requiring medical focus is ulcer and
gastro esophagealdisease1. In the US, approximately 4 million people have
peptic ulcer (duodenal and gastric types), and 350 thousand new patient are
diagnosed in each year, around 180 thousand peoples are admitted to
hospital and treated with drugs yearly, and about five thousand patient from
this case die each year as a result of ulcer condition. The lifetime of human
being developing a peptic ulcer is about 10 percentages for Americans males
and four percentages for female population2.
Peptic ulcers is wound in the lesions in the stomach and GIT that are most
often affected in younger to older adults population, but this may diagnosed
in young adult life. They often appear without obvious sign and symptom, after
a period of days to months of active phase of disease, it may heal with or
without drug treatment. It also affect because of bacterial infections with H.
Pylori. AIM AND OBJECTIVE: GIT disease against few effective drugs available for modern therapy, it
produce side effect during the treatment is worse than the condition of
rebound acidity. as per the literature review selected plant that cure ulcer
diseases so considerable interest has developed in the examination of these
numerous plants remedies which are useful for antiulcer activity. So it is
necessary to find new drugs of importance in antiulcer effect with fewer side
effects. Moreover it is necessary to required scientific validation traditionally
using medicinal plants on various systems such as Ayurvedic Siddha Unani
systems.
In our study Desmostachyabipinnata plant extracts its phytochemical
investigation will be a useful tool for the identification and authentication of the
plant for industrial and further research purpose, which will be related to the
antioxidant activity. Antioxidants, which can scavenge free radicals, have an
important role in pharmacological systems. Antioxidants are emerging as
prophylactic and therapeutic agents. Hence, antioxidant was also evaluated
for the potent extract. And now I have under taken the study of evaluation
anti-oxidant and antiulcer activity of Desmostachyabipinnata plant extracts by
using invivo and invitro methods
To select plant based on their ethnomedical uses and preparation
of their extracts.
1. To screen phytochemical profile.
2. To screen the selected extract for antioxidant using various invitro
methods
3. To screen the potent plant extract for their invitro antioxidant,
4. To evaluate invivo antiulcer activities by NSAIDs induced animal
model. SUMMARY AND CONCLUSION: The present study is evaluated the antioxidant potential and antiulcer
effect of AEDB. The results analysed from the present study have indicate
that AEDB possesses antioxidant and antiulcer effect on aspirin induced
ulcers.
The preliminary phytochemical screening of whole plant extracts indicate
in presence of flavonoid, alkaloid, proteins,amino acids and terpenoids, fixed
oil and glycosides
Pre-treatment with AEDB particularly at a dose of 400mg/kg in a single
schedule and 400mg/Kg treatment significantly reduce the ulcer index value,
total acidity concentration, total volume of acid release and total protein and
increase value pH and glutathione content as compared with 100
mg/kg,200mg/kg and control groups.
The antioxidant screening shows that it showed reducing power to DPPH
radicals. But the efficiency showed that far below from Vitamin C. The
concentration of the AEDB needed to scavenge 50% superoxide anion (IC50)
equal to that of standard hence the plant extract have the significant
antioxidant activity
The antiulcer effect is screened in ethanol extract of
Desmostachyabipinnata on NSAID induced anti-ulcer study. The results get
from these study have been shown that ethanol extract of
Desmostachyabipinnata produce antiulcer effect.In aspirin induced model,
there is reduction in ulcer index, total acidity, total volume of gastric contents,
total protein concentration and higher concentration of glutathione content and
pH of gastric secretion they compared with control group. Famotidine used as
a standard comparison agents. Famotidine used as H2 receptor blocker, is
significantly reduce about 90% of basal, food induced and hormonal mediated
gastric acid, which again induced by histamine, gastrin, parasympathomimetic
drugs and vagal stimulation. Famotidine mediate its suppression of gastric
secretion by inhibiting the histamine mediated c-AMP dependent pathway Famotidine encouraged certain type mucus analogues of gastric mucus for
patients with duodenal ulcer.
Total acidity responsible quantification acid is present in the gastric
secretion. It has a important aggressive factor which induced the ulcer.
Gastric release is maintained by vagal control and higher activity of vagus
stimulation also contributes to ulcer formation. On ethanol administration, the
mucosal mast cells mediate to secretion of vasoactive mediators containing
histamine. Histamine is mediated to stimulate the synthesis of cyclic AMP
through activation of the enzyme adenylcyclase which mediate the activation
of gastric proton pump and secrete of hydrogen ions. The treatment of
extracts showed reduce the total acidity of the gastric contents.
Serum protein including albumin and globulin. In the peptic ulcer the total
protein concentration of serum or gastric secretion are increased. This may be
due to leakage of plasma protein in to the gastric secretion or serum with
lower mucosal resistance/barrier of the gastric mucosal layer.After treatment
with AEDB there was a significant reduction in protein concentration of gastric
juice which enhancing leakage of plasma proteins.
Acid volume is amount (in ml) of acid release in the gastric content release
contain HCl, pepsinogen enzyme, mucus secretion, bicarbonates
concentration, intrinsic factor and proteins. Amount of acid release is an
important factor responsible for the production of ulcer mediated by exposure
of the unprotected lumen of stomach by concentrated acids. AEDB treatment
showed decrease in the acid volume of the gastric secretion.
Increased pH shows a lower concentration of the hydrogen ion. The
hydrogen ion is a major triggering factor responsible for the etiologic factor for
ulcer and gastric damage. AEDBtreatment indicate higher concentration of pH
of the gastric juices. This values directly shown the AEDB reduce possibility of
ulcer and has a protective effect of surface of the gastric mucosa.
In gastric ulcer tissues, Glutathione (g-glutamylcysteinylglycine, GSH)
levels were found to be decreased112
. aspirin-induced genesis of free radical
concentration reduces the cysteine concentration which mediated for GSH released.Values from this study responsible for depletion of gastric GSH is
related with induction of gastric lesion in the rats. GSH is a tripeptide and
having a superoxide radical scavenger and it protect thiol protein contents
essential for release the integrity of tissue against oxidation reaction. In my
present study, AEDB treatment showed increase in the glutathione content
A study to evaluate the effect of mirror therapy on upper extremity motor functions in stroke patients.
INTRODUCTION : Mirror therapy is relatively new therapeutic intervention for stroke
patients. It is a simple, inexpensive and, most importantly, patientdirected
treatment that may improve upper-extremity function. It involves
performing movements of unimpaired limb while watching its mirror
reflection superimposed over the (unseen) impaired limb (motor
imagery). It creates a visual illusion of enhanced movement capability of
the impaired limb.
AIM AND OBJECTIVE :
To evaluate the effect of Mirror therapy on upper extremity motor functions in stroke patients.
METHODS :
22 patients with one attack of stroke, duration of
illness between 2 to 12 months and brunnstrom stage of motor recovery
between 1 to 3 with no cognitive impairment (MMSE>23). Patients were
randomly divided into 2 groups: Group A and Group B. Patients in group
A were treated with Mirror therapy and conventional therapy; where as in
group B, patients were treated with placebo Mirror therapy and
conventional therapy. ARAT and FGMR were used to assess motor
functions before and after intervention.
RESULT : Then data was tabulated and analyzed statistically. Paired and
unpaired t-tests were used to evaluate effect of interventions in both
groups and the effect of mirror therapy on upper extremity motor
functions compared to control group respectively.
The analysis leads to inference that mirror therapy along with
conventional therapy showed batter result when compared to intervention
in control group.
Mirror therapy was found to be effective in improving upper
extremity motor functions in stroke patients.
CONCLUSION :
This study concludes that Mirror therapy improves upper extremity motor functions in stroke patients
Comparison of pulmonary functions of children who outgrew asthma symptoms with pulmonary functions of children without asthma
Background: Asthma treatment guidelines recommend that inhaled corticosteroids (ICS) can be stopped in children if they remain asymptomatic on its lowest dose. However, the effect of stopping steroids on their pulmonary function largely remains unknown. Objective: The objective of the study was to compare the lung function parameters of children with persistent asthma, who were treated with ICS for at least 1 year and are now remaining asymptomatic after stopping them for ≥1 year (children who outgrew asthma), with the lung function parameters of children in same age group without asthma. Materials and Methods: The study design was cross-sectional comparative study, and it was conducted in the pediatric asthma clinic of a tertiary level teaching hospital in South India from August 2017 to July 2018. The study included 54 children in the age group of 6–18 years with asthma, nowremaining asymptomatic after stopping ICS for ≥1 year and 54 children in same age group without asthma. Spirometry was done in both groups. Post-bronchodilator reversibility testing was done for children with asthma. Results: The median values of forced expiratory volume in one second (FEV1), FEV1%, FEV1/forced vital capacity (FVC) ratio, peak expiratory flow (PEF), PEF%, forced expiratory flow 25-75 (FEF25-75), and FEF25-75% were observed to be significantly lower in children who outgrew asthma symptoms, when compared with children without asthma. A statistically significant number of children who outgrew their asthma had FEV1% <80%, FEV1/FVC ratio <80%, PEF% <80%, and FEF25-75% <80% when compared to children without asthma. After inhalation of short-acting beta-agonist, 18 children (33.3%) who had outgrown asthma symptoms had FEV1 reversibility more than 12%. Conclusion: The pulmonary functions of children with bronchial asthma who were remaining asymptomatic for more than 1 year after stopping ICS were significantly lower than children without asthma. 
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