Which Is the Best Parametric Statistical Method For Analyzing Delphi Data?

This study compares the three parametric statistical methods: coefficient of variation, Pearson correlation coefficient, and F-test to obtain reliability in a Delphi study that involved more than 100 participants. The results of this study indicated that coefficient of variation was the best procedure to obtain reliability in such a study

Analyzing The Effect Of Top Management Support On Information System (IS) Performance Across Organizations And Industries Using Hierarchical Linear Modeling

Top management support has long been conceivable as an important factor for the success of IS projects. Due to the hierarchical nature of an organization, a cross-level interaction can occur among nested levels. Thus, using inappropriate statistical analysis can cause misleading results and lost of information. This study provides two contributions to the IS research. First, Hierarchical Linear Modeling (HLM) was used to explain the cross-level interaction between organizational level and industry level. Second, unlike other studies focusing on an organizational level, this study considers top management support at the industry level and examines the mediating role of top management support between the two levels

PENGARUH PEMBERIAN PUPUK CAIR DENGAN DOSIS BERBEDA TERHADAP KANDUNGAN NUTRISI RUMPUT BENGGALA (Panicum maximum) PADA LAHAN KERING KRITIS

-Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian pupuk cair dengan dosis berbeda terhadap pertumbuhan dan kandungan nutrisi rumput benggala pada lahan kering kritis. Penelitian ini dilaksanakan pada bulan April sampai Juni 2016 di Desa Bulo, Kecamatan Panca Rijang Kabupaten Sidenreng Rappang. Penelitian ini dirancang dengan menggunakan Rancangan Acak Kelompok (RAK). Rancangan penelitian terdiri 4 perlakuan dengan 3 kali ulangan. Perlakuan Penelitian yaitu B0= kontrol, B1= 20 ml/ petak, B2= 40 ml/petak, B3=60 ml/petak.Luas petak masing-masing perlakuan adalah 10 m2. Jarak tanam 40 cm x 60 cm. Jumlah Anakan rumput benggala terdiri dari 2 anakan yang dimasukan ke dalam lubang yang sudah disiapkan dengan kedalaman tanam 5 cm. Hasil penelitian menunjukkan bahwa perlakuan B3 pengaruhnya nyata lebih signifikan (P<0,01) terhadap pertumbuhan rumput benggala pada perlakuan B3 (tinggi tanaman dan jumlah anakan, luas daun dan jumlah klorofil). Hasil penelitian ini dapat disimpulkan bahwa pemberian pupuk cair dengan dosis berbeda pada lahan kering kritis dapat meningkatkan kandungan nutrisi rumput benggal

Meta-analysis methods for synthesizing treatment effects in multisite studies: hierarchical linear modeling (HLM) perspective

The objectives of the present mixed-effects meta-analytic application are to provide practical guidelines to: (a) Calculate treatment effect sizes from multiple sites; (b) Calculate the overall mean of the site effect sizes and their variances; (c) Model the heterogeneity in these site treatment effects as a function of site and program characteristics plus unexplained random error using Hierarchical Linear Modeling (HLM); (d) Improve the ability of multisite evaluators and policy makers to reach sound conclusions about the effectiveness of educational and social interventions based on multisite evaluations; and (e) Illustrate the proposed methodology by applying these methods to real multi-site research data. Accessed 58,759 times on https://pareonline.net from June 23, 2003 to December 31, 2019. For downloads from January 1, 2020 forward, please click on the PlumX Metrics link to the right

Small-molecule targeting of translation initiation for cancer therapy

Translation initiation plays a critical role in the regulation of cell growth and tumorigenesis. We report here that inhibiting translation initiation through induction of eIF2α phosphorylation by small-molecular-weight compounds restricts the availability of the eIF2·GTP·Met-tRNAi ternary complex and abrogates the proliferation of cancer cells in vitro and tumor growth in vivo. Restricting the availability of the ternary complex preferentially down-regulates the expression of growth-promoting proteins and up-regulates the expression of ER stress response genes in cancer cells as well as in tumors excised from either animal models of human cancer or cancer patients. These findings provide the first direct evidence for translational control of gene-specific expression by small molecules in vivo and indicate that translation initiation factors are bona fide targets for development of mechanism-specific anti-cancer agents

CO<inf>2</inf> absorption using diethanolamine-water solutions in a rotating spiral contactor

Results for mass transfer in a rotating spiral device are presented here for absorption of carbon dioxide from nitrogen carrier gas using mixtures of diethanolamine (DEA) and water. The ability of the device to examine the full range of flow rate ratio for the two phases while controlling the relative thicknesses of the phase layers is applied to surveying absorption performance over a wide range of DEA concentration at 312 K and 1.8 bara. Comparisons are made for a fixed 86 μm liquid layer thickness, which is shown to fix also the fraction of the liquid accessible by diffusion, while maintaining 90% removal of CO2 from a gas stream of 10% (mole) CO2 in nitrogen. The increasing liquid viscosity with DEA fraction is countered by reducing the liquid flow rate to maintain constant liquid layer thickness and diffusion depth. The allowed gas throughput, while meeting 90% removal, increases with DEA concentration until the increasing viscosity gives sufficient reduction in liquid flow rate to offset the increasing CO2 capacity of the liquid. The maximum gas flow rate has a broad peak centred at a DEA mole fraction of about 0.072 (31% by mass). Utilisation of the amine is increased as DEA concentration increases, apparently as a result of the longer residence time, suggesting an effect of chemical time scales on the order of seconds. For a fixed concentration, full utilisation of the amine is achieved by decreasing the liquid flow rate, which reduces layer thickness and increases diffusion time. The work highlights the use of the rotating spiral for rapid and accurate testing to determine optimum liquid composition of absorbent formulations

Thyroidal angiogenesis in zebrafish (Danio rerio) exposed to high perchlorate concentration

As a well known environmental contaminant, perchlorate inhibits thyroidal iodide uptake and reduces thyroid hormone levels. In zebrafish (Danio rerio) exposed to high concentrations of sodium perchlorate (200, 350 and 500 mg/L) for 10 days, remarkable angiogenesis was identified, not onlyhistopathologically but also statistically by counting of the small, medium and large sized (grades 1 to 3) vessels per unit area. Angiogenic response is concluded as the most sensitive parameter for rating of high concentrations of perchlorate exposure

A scoping review of media campaign strategies used to reach populations living with or at high risk for Hepatitis C in high income countries to inform future national campaigns in the United Kingdom

BACKGROUND: With the advent of direct acting antivirals, the World Health Organisation proposed eliminating Hepatitis C as a public health threat by 2030. To achieve this, countries need to diagnose, engage in care and treat their undiagnosed populations. This will require sensitisation campaigns. However previous media campaigns have had mixed impact. We conducted a scoping review to identify and understand the impact of previous Hepatitis C media campaigns. These findings could inform the delivery of future campaigns. METHODS: We searched five electronic databases for published literature on media campaigns conducted for Hepatitis C awareness, testing, and treatment in Organisation for Economic Co-operation and Development (OECD) countries since 2010. Two independent reviewers screened citations for inclusion. Additionally, we spoke to stakeholders in the Hepatitis C field in the UK and conducted a Google search to identify any unpublished literature. A quantitative synthesis was conducted to identify targeted populations, strategies and media used, aims and impact of the campaigns. RESULTS: A title and year of publication screening of 3815 citations resulted in 113 papers that had a full abstract screen. This left 50 full-text papers, 18 were included of which 9 (50%) were from Europe. 5 (27.8%) of campaigns targeted minority ethnicities, and 9 (50%) aimed to increase testing. A Google search identified 6 grey literature sources. Most campaigns were not evaluated for impact. Discussions with stakeholders identified several barriers to successful campaigns including lack of targeted messaging, stigmatising or accusatory messaging, and short-lived or intermittent campaign strategies. CONCLUSION: Future campaigns will likely need to be multifaceted and have multiple tailored interventions. Campaigns will need to be sizeable and robust, integrated into health systems and viewed as an ongoing service rather than one-offs

Late-Onset Parry-Romberg Syndrome With Atypical Neurological Manifestations: A Case Report

Parry-Romberg Syndrome (PRS) is a rare neurocutaneous disorder characterized by gradual facial hemiatrophy. We present a case study of a 64-year-old woman with late-onset PRS and linear scleroderma. The patient exhibited atypical PRS symptoms including leg numbness, hyper-reflexia, trigeminal neuralgia, and severe headaches. Diagnostic evaluations revealed chronic left-sided cerebral infarction, microhemorrhages, and nerve involvement. Treatment options for PRS are limited and aim to manage symptoms. This case highlights the diagnostic challenges of late-onset PRS, emphasizing interdisciplinary approach. Further research and improved therapies are essential for better patient outcomes