71 research outputs found
Vector-meson contributions do not explain the rate and spectrum in K_L -> pi0 gamma gamma
We analyze the recent NA48 data for the reaction K_L -> pi0 gamma gamma with
and without the assumption of vector meson dominance (VMD). We find that the
data is well described by a three-parameter expression inspired by O(p^6)
chiral perturbation theory. We also find that it is impossible to fit the shape
of the decay distribution and the overall rate simultaneously if one imposes
the VMD constraints on the three parameters. We comment on the different fits
and their implications for the CP-conserving component of the decay K_L -> pi0
e+ e-.Comment: Version accepted for publication on Phys. Rev. D. 19 pages, LaTeX, 8
figures, uses epsf.st
New Fermions at ee Colliders: I. Production and Decay
We analyze the production in collisions of new heavy fermions
stemming from extensions of the Standard Model. We write down the most general
expression for the production of two heavy fermions and their subsequent
decays, allowing for the polarization of the ee initial state and
taking into account the final polarization of the fermions. We then discuss the
various decay modes including cascade and three body decays, and the production
mechanisms, both pair production and single production in association with
ordinary fermions.Comment: 21 pages (no figures), Preprint UdeM-LPN-TH-93-15
K_S\rightarrow \gamma\gamma , K_L\rightarrow\pi^0\gamma\gamma$ and Unitarity
Agreement between the experimental value and the number predicted via a one-loop chiral perturbation
theory calculation has been cited as a success for the latter. On the other
hand the one-loop prediction for the closely related process has been found to be a factor three below the experimental
value. Using the inputs of unitarity and dispersion relations, we demonstrate
the importance of higher order loop effects to both of these processes.Comment: 20 pages (4 figures available on request), UMHEP-39
CP Phases in Correlated Production and Decay of Neutralinos in the Minimal Supersymmetric Standard Model
We investigate the associated production of neutralinos
accompanied by the neutralino
leptonic decay , taking into
account initial beam polarization and production-decay spin correlations in the
minimal supersymmetric standard model with general CP phases but without
generational mixing in the slepton sector. The stringent constraints from the
electron EDM on the CP phases are also included in the discussion. Initial beam
polarizations lead to three CP--even distributions and one CP--odd
distribution, which can be studied independently of the details of the
neutralino decays. We find that the production cross section and the branching
fractions of the leptonic neutralino decays are very sensitive to the CP
phases. In addition, the production--decay spin correlations lead to several
CP--even observables such as lepton invariant mass distribution, and lepton
angular distribution, and one interesting T--odd (CP--odd) triple product of
the initial electron momentum and two final lepton momenta, the size of which
might be large enough to be measured at the high--luminosity future
electron--positron collider or can play a complementary role in constraining
the CP phases with the EDM constraints.Comment: Revtex, 37 pages, 12 eps figure
Interleukin 6 in autoimmune and inflammatory diseases: a personal memoir
In this review, the author discusses the research that led to the identification and characterization of interleukin 6 (IL-6), including his own experience isolating IL-6, and the roles this cytokine has on autoimmune and inflammatory diseases. The cDNAs encoding B-cell stimulatory factor 2 (BSF-2), interferon (IFN)-β2 and a 26-kDa protein were independently cloned in 1986, which in turn led to the identification of each. To resolve the confusing nomenclature, these identical molecules were named IL-6. Characterization of IL-6 revealed a multifunctional cytokine that is involved in not only immune responses but also hematopoiesis, inflammation, and bone metabolism. Moreover, IL-6 makes significant contributions to such autoimmune and inflammatory diseases as rheumatoid arthritis (RA)
Chronic Allograft Nephropathy Score Before Sirolimus Rescue Predicts Allograft Function in Renal Transplant Patients
Properties of the Top Quark
The top quark was discoverd at the CDF and D0 experiments in 1995. As the
partner of the bottom quark its properties within the Standard Model are fully
defined. Only the mass is a free parameter. The measurement of the top quark
mass and the verification of the expected properties have been an important
topic of experimental top quark physics since. In this review the recent
results on top quark properties obtained by the Tevatron experiments CDF and D0
are summarised. At the advent of the LHC special emphasis is given to the basic
measurement methods and the dominating systematic uncertainties.Comment: Habilitation thesis, revised and updated for publication in EPJ
Meta-analysis of type 2 Diabetes in African Americans Consortium
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by genome-wide association studies (GWAS) in individuals of European ancestry. In order to investigate the genetic architecture of T2D in African Americans, the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium examined 17 GWAS on T2D comprising 8,284 cases and 15,543 controls in African Americans in stage 1 analysis. Single nucleotide polymorphisms (SNPs) association analysis was conducted in each study under the additive model after adjustment for age, sex, study site, and principal components. Meta-analysis of approximately 2.6 million genotyped and imputed SNPs in all studies was conducted using an inverse variance-weighted fixed effect model. Replications were performed to follow up 21 loci in up to 6,061 cases and 5,483 controls in African Americans, and 8,130 cases and 38,987 controls of European ancestry. We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 × 10(-94)<P<5 × 10(-8), odds ratio (OR) = 1.09 to 1.36). Fine-mapping revealed that 88 of 158 previously identified T2D or glucose homeostasis loci demonstrated nominal to highly significant association (2.2 × 10(-23) < locus-wide P<0.05). These novel and previously identified loci yielded a sibling relative risk of 1.19, explaining 17.5% of the phenotypic variance of T2D on the liability scale in African Americans. Overall, this study identified two novel susceptibility loci for T2D in African Americans. A substantial number of previously reported loci are transferable to African Americans after accounting for linkage disequilibrium, enabling fine mapping of causal variants in trans-ethnic meta-analysis studies.Peer reviewe
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