GAMBARAN PERSEPSI TOKOH MASYARAKAT TENTANG COVID-19 DI WILAYAH KERJA UPTD PUSKESMAS HALIWEN KABUPATEN BELU PROVINSI NUSA TENGGARA TIMUR

Latar Belakang: Virus Corona adalah virus yang menyerang sistem pernapasan. Penyakit karena infeksi virus ini disebut COVID-19. Virus ini bisa menyebabkan gangguan ringan pada sistem pernapasan, infeksi paru-paru yang berat hingga kematian. Situasi COVID-19 hingga saat ini di tingkat global maupun nasional masih dalam risiko sangat tinggi. Selama penyebaran vaksin masih dalam proses, dunia dihadapkan pada kenyataan untuk mempersiapkan diri hidup berdampingan dengan COVID-19. Tujuan: Mengetahui persepsi tokoh masyarakat tentang COVID-19 di Wilayah kerja UPTD Puskesmas Haliwen. Metode Penelitian: menggunakan metode penelitian kualitatif dengan pendekatan fenomenologi. Fenomenologi menjelaskan fenomena dan maknanya bagi individu dengan melakukan wawancara pada sejumlah individu. Hasil penelitian: ditemukan beberapa tema, yaitu, variasi tanda dan gejala COVID-19, Peran pemerintah dalam penganan Covid-19, Sikap Masyarakat terhadap Covid-19. Kesimpulan:. Persepsi tentang gejala Covid-19 Berdasarkan hasil penelitian didapatkan bahwa Partisipan memahami tanda dan gejala Covid-19 yaitu demam, batuk, flu, diare, kehilangan indra perasa, sakit kepala, tenggorokan gatal, dan nyeri pada anggota tubuh, Persepsi tentang kepatuhan perlindungan diri dari penularan Covid-19 di wilayah desa Kabuna Haliwen, yaitu yang dilakukan partisipan memakai masker, mencuci tangan dan menjaga jarak. Ada beberapa partisipan yang sudah paham tentang cara perlindungan diri, persepsi masyarakat tentang Covid-19 yaitu di mana sebagian partisipan mengatakan percaya dan tidak percaya tentang Covid-19 maka masih perlunya peran tenaga kesehatan untuk menginformasikan mengenai Covid-19

PENGUATAN KEWENANGAN LEMBAGA BADAN PENGAWAS PEMILU DALAM PENEGAKAN HUKUM PEMILU

This study is based on the high administrative and criminal violations in the elections in Indonesia, so an assessment is needed to strengthen the authority of Bawaslu in the implementation of elections, in order to improve the quality of elections, and create good electoral law enforcement practices in Indonesia. To study this matter, hence in this research a normative juridical research, using approach statute approach, historical, conseptual, case, and comparative approaches was employed. Then the collected legal materials were descriptively and qualitatively analyzed. The strengthening of this delicate authority is accomplished by accompanying improvement in some other vital aspects such as the regulatory improvements on the institutional and electoral arrangements that give Bawaslu a more assertiveness space that is more ideal in the electoral law enforcement. Keywords: Bawaslu, Strengthening Authority, Law Enforcement, Electio

An Adverse Outcome Pathway for Sensitization of the Respiratory Tract by Low-Molecular-Weight Chemicals: Building Evidence to Support the Utility of In Vitro and In Silico Methods in a Regulatory Context

Sensitization of the respiratory tract is an important occupational health challenge, and understanding the mechanistic basis of this effect is necessary to support the development of toxicological tools to detect chemicals that may cause it. Here we use the adverse outcome pathway (AOP) framework to organize information that may better inform our understanding of sensitization of the respiratory tract, building on a previously published skin sensitization AOP, relying on literature evidence linked to low-molecular-weight organic chemicals and excluding other known respiratory sensitizers acting via different molecular initiating events. The established key events (KEs) are as follows: (1) covalent binding of chemicals to proteins, (2) activation of cellular danger signals (inflammatory cytokines and chemokines and cytoprotective gene pathways), (3) dendritic cell activation and migration, (4) activation, proliferation, and polarization of T cells, and (5) sensitization of the respiratory tract. These events mirror the skin sensitization AOP but with specific differences. For example, there is some evidence that respiratory sensitizers bind preferentially to lysine moieties, whereas skin sensitizers bind to both cysteine and lysine. Furthermore, exposure to respiratory sensitizers seems to result in cell behavior for KEs 2 and 3, as well as the effector T cell response, in general skewing toward cytokine secretions predominantly associated with T helper 2 (Th2) response. Knowledge gaps include the lack of understanding of which KE(s) drive the Th2 polarization. The construction of this AOP may provide insight into predictive tests that would in combination support the discrimination of respiratory-sensitizing from non- and skin-sensitizing chemicals, a clear regulatory need

Differential performance in examinations at 16+ English and mathematics - appendices

Final report held at GPE/4839SIGLEAvailable from British Library Document Supply Centre-DSC:GPE/4840 / BLDSC - British Library Document Supply CentreGBUnited Kingdo