575 research outputs found
Effects of a 6-week Low-Carbohydrate High-Fat Diet on Lipid Profiles in Competitive Recreational Distance Runners
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Effects of a Low Carbohydrate Diet Versus a High Carbohydrate Diet on 5-km Running Performance
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Creating Brand Meaning: A Review and Research Agenda
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/150608/1/jcpy1122.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/150608/2/jcpy1122_am.pd
A relocatable ocean model in support of environmental emergencies
During the Costa Concordia emergency case, regional, subregional, and relocatable ocean models have been used together with the oil spill model, MEDSLIK-II, to provide ocean currents forecasts, possible oil spill scenarios, and drifters trajectories simulations. The models results together with the evaluation of their performances are presented in this paper. In particular, we focused this work on the implementation of the Interactive Relocatable Nested Ocean Model (IRENOM), based on the Harvard Ocean Prediction System (HOPS), for the Costa Concordia emergency and on its validation using drifters released in the area of the accident. It is shown that thanks to the capability of improving easily and quickly its configuration, the IRENOM results are of greater accuracy than the results achieved using regional or subregional model products. The model topography, and to the initialization procedures, and the horizontal resolution are the key model settings to be configured. Furthermore, the IRENOM currents and the MEDSLIK-II simulated trajectories showed to be sensitive to the spatial resolution of the meteorological fields used, providing higher prediction skills with higher resolution wind forcing.MEDESS4MS Project; TESSA Project; MyOcean2 Projectinfo:eu-repo/semantics/publishedVersio
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Exome sequencing of Finnish isolates enhances rare-variant association power.
Exome-sequencing studies have generally been underpowered to identify deleterious alleles with a large effect on complex traits as such alleles are mostly rare. Because the population of northern and eastern Finland has expanded considerably and in isolation following a series of bottlenecks, individuals of these populations have numerous deleterious alleles at a relatively high frequency. Here, using exome sequencing of nearly 20,000 individuals from these regions, we investigate the role of rare coding variants in clinically relevant quantitative cardiometabolic traits. Exome-wide association studies for 64 quantitative traits identified 26 newly associated deleterious alleles. Of these 26 alleles, 19 are either unique to or more than 20 times more frequent in Finnish individuals than in other Europeans and show geographical clustering comparable to Mendelian disease mutations that are characteristic of the Finnish population. We estimate that sequencing studies of populations without this unique history would require hundreds of thousands to millions of participants to achieve comparable association power
Volume 02
Introduction from Dean Dr. Charles Ross
Mike\u27s Nite: New Jazz for an Old Instrument by Joseph A. Mann
Investigation of the use of Cucumis Sativus for Remediation Of Chromium from Contaminated Environmental Matrices: An Interdisciplinary Instrumental Analysis Project by Kathryn J. Greenly, Scott E. Jenkins, and Andrew E. Puckette
Development of GC-MS and Chemometric Methods for the Analysis of Accelerants in Arson Cases by Scott Jenkins
Building and Measuring Scalable Computing Systems by Daniel M. Honey and Jeffery P. Ravenhorst
Nomini Hall: A Case Study in the Use of Archival Resources as Guides for Excavation at An Archaeological Site by Jamie Elizabeth Mesrobian
Two Stories: In Ohio and How to Stay Out of the Brazilian Army by Thomas Scott
Forgerson des Hommes/Stealing the Steel in Zola\u27s Men by Jay Crowell
Paul Gauguin\u27s Escape into Primitivism by Sarah Spangenberg
Lee Krasner, Abstract Expressionist by Amy S. Eason
Artist Book âParisâ by Kenny Wolfe
Artist Book âSequence of Every Dayâ by Liz Hale
Artist Book âApple Treeâ by Rachel Bouchard
Artist Book âNot so Pretty in Pinkâ by Will Semonco
Artist Book âLook into the Moonâ by Carley York
Artist Books âExtraâ and âGreenâ by Ryan Higgenbothom
Artist Book âRe-growing Appalachiaâ by Adrienne Heinbaugh
Artist Books âCheeziestâ, âUh-ohâ and âThe Girl with the Glassesâ by Melissa Dorton
âSelf-Reflectionâ by Madeline Hunter
Artist Book âThe Princess and the Frogâ by June Ashmore
âHunterâs Nicheâ and âThe Wildâ by Clark Barkley
âTo Thine Own Self be Trueâ by Jay Haley
âNot Funnyâ Ten-Minute Play Festiva
The first legal mortgagor: a consumer without adequate protection?
This article contends that the UK governmentâs attempt to create a well-functioning consumer credit market will be undermined if it fails to reform the private law framework relating to the first legal mortgage. Such agreements are governed by two distinct regulatory regimes that are founded upon very different conceptions of the mortgagor. The first, the regulation of financial services overseen by the Financial Conduct Authority, derives from public law and is founded upon a conception of the mortgagor as âconsumerâ. The other is land law, private law regulation implemented by the judiciary and underpinned by a conception of the mortgagor as âlandownerâ. Evidence suggests that the operation of these two regimes prevents mortgagors from receiving fair and consistent treatment. The current reform of financial services regulation therefore will change only one part of this governance regime and will leave mortgagors heavily reliant upon a regulator that still has to prove itself. What this article argues is that reform of the rules of private law must also be undertaken with the aim of initiating a paradigm shift in the conception of the mortgagor from âlandownerâ to âconsumerâ. Cultural shifts of this kind take time but the hope is that this conceptual transformation will occur in time to deter the predicted rise in mortgage possessions
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Concise total syntheses of (â)-jorunnamycin A and (â)-jorumycin enabled by asymmetric catalysis
The bis-tetrahydroisoquinoline (bis-THIQ) natural products have been studied intensively over the past four decades for their exceptionally potent anticancer activity, in addition to strong gram-positive and -negative antibiotic character. Synthetic strategies toward these complex polycyclic compounds have relied heavily on electrophilic aromatic chemistry, such as the Pictet-Spengler reaction, that mimics their biosynthetic pathways. Herein we report an approach to two bis-THIQ natural products, jorunnamycin A and jorumycin, that instead harnesses the power of modern transition-metal catalysis for the three major bond-forming events and proceeds with high efficiency (15 and 16 steps, respectively). By breaking from biomimicry, this strategy allows for the preparation of a more diverse set of non-natural analogs
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