Sampling Errors in Observed Gravity Wave Momentum Fluxes from Vertical and Tilted Profiles

Observations from radiosondes or from vertically pointing remote sensing profilers are often used to estimate the vertical flux of momentum due to gravity waves. For planar, monochromatic waves, these vertically integrated fluxes are equal to the phase averaged flux and equivalent to the horizontal averaging used to deduce momentum flux from aircraft data or in numerical models. Using a simple analytical solution for two-dimensional hydrostatic gravity waves over an isolated ridge, it is shown that this equivalence does not hold for mountain waves. For a vertical profile, the vertically integrated flux estimate is proportional to the horizontally integrated flux and decays with increasing distance of the profile location from the mountain. For tilted profiles, such as those obtained from radiosonde ascents, there is a further sampling error that increases as the trajectory extends beyond the localised wave field. The same sampling issues are seen when the effects of the Coriolis force on the gravity waves are taken into account. The conclusion of this work is that caution must be taken when using radiosondes or other vertical profiles to deduce mountain wave momentum fluxes

(Photo)Electrocatalytic CO2 Reduction at the Defective Anatase TiO2 (101) Surface

Excessive carbon dioxide (CO2) emissions by combustion of fossil fuels are linked to global warming and rapid climate change. One promising route to lowering the concentration of CO2 in the atmosphere is to reduce it to useful small molecules via photoelectrocatalytic hydrogenation, which would enable solar energy storage with a zero-carbon emission cycle and perform a more efficient separation of the photogenerated electron and hole pair than pure photocatalysis. Indeed, photoelectrocatalytic CO2 reduction has been an intense focus of research. Using the density functional theory (DFT), we studied the CO2 reduction reaction on the defective anatase TiO2 (101) surface, at both the solvent/catalyst and the electrolyte/catalyst interfaces. The analysis of the electronic structure of the surface shows a contrast between the solvent/catalyst and the electrolyte/catalyst interfaces, which results in the two corresponding catalytic cycles being distinct. Our study explains at the electronic and mechanistic levels why methanol is the main product in the presence of the electrolyte and why the overpotential is not only controlled by the reaction process but also by the diffusion process

Assessment of valley cold pools and clouds in a very high-resolution numerical weather prediction model

The formation of cold air pools in valleys under stable conditions represents an important challenge for numerical weather prediction (NWP). The challenge is increased when the valleys that dominate cold pool formation are on scales unresolved by NWP models, which can lead to substantial local errors in temperature forecasts. In this study a 2-month simulation is presented using a nested model con- figuration with a finest horizontal grid spacing of 100 m. The simulation is compared with observations from the recent COLd air Pooling Experiment (COLPEX) project and the model’s ability to represent cold pool formation, and the surface energy balance is assessed. The results reveal a bias in the model long-wave radiation that results from the assumptions made about the sub-grid variability in humidity in the cloud parametrization scheme. The cloud scheme assumes relative humidity thresholds below 100 % to diagnose partial cloudiness, an approach common to schemes used in many other models. The biases in radiation, and resulting biases in screen temperature and cold pool properties are shown to be sensitive to the choice of critical relative humidity, suggesting that this is a key area that should be improved for very high-resolution modeling

A case‐study of cold‐air pool evolution in hilly terrain using field measurements from COLPEX

A case‐study investigation of cold‐air pool (CAP) evolution in hilly terrain is conducted using field measurements made during IOP 16 of the COLd‐air Pool EXperiment (COLPEX). COLPEX was designed to study cold‐air pooling in small‐scale valleys typical of the UK (∼100–200 m deep, ∼1 km wide). The synoptic conditions during IOP 16 are typical of those required for CAPs to form during the night, with high pressure, clear skies and low ambient winds. Initially a CAP forms around sunset and grows uninterrupted for several hours. However, starting 4 hr after sunset, a number of interruptions to this steady cooling rate occur. Three episodes are highlighted from the observations and the cause of disruption attributed to (a) wave activity, in the form of gravity waves and/or Kelvin–Helmholtz (KH) instability, (b) increases in the above‐valley winds resulting from the development of a nocturnal low‐level jet (NLLJ), (c) shear‐induced mixing resulting from instability of the NLLJ. A weakly stable residual layer provides the conditions for wave activity during Episode 1. This residual layer is eroded by a developing NLLJ from the top down during Episode 2. The sustained increase in winds at hill‐top levels – attributed to the NLLJ – continue to disrupt the CAP through Episode 3. Although cooling is interrupted, the CAP is never completely eroded during the night. Complete CAP break‐up occurs some 3.5 hr after local sunrise. This case‐study highlights a number of meteorological phenomena that can disrupt CAP evolution even in ideal CAP conditions. These processes are unlikely to be sufficiently represented by current operational weather forecast models and can be challenging even for high‐resolution research models

Development and Application of Ligand-Exchange Reaction Method for the Determination of Clonazepam

Purpose: This paper presents an improved kinetic-spectrophotometric procedure for determining clonazepam (CZP) in pharmaceutical formulations and human serum.Methods: The method is based on ligand-exchange reaction. The reaction was followed spectrophotometrically by measuring the rate of change of absorbance at 425 nm in ethanolic sodium hydroxide solution.Results: The optimum operating conditions for reagent concentrations and temperature were established. Linear calibration curve was obtained in the range of 0.32 - 4.10 μg mL-1. The optimized conditions yielded a theoretical detection limit of 0.24 μg mL-1 based on the 3.3So criterion, where S0 is standard deviation of the calibration line. The interference of certain drugs, foreign ions and amino acids on the reaction rate were studied in order to assess the selectivity of the method.Conclusion: The developed method is sensitive, accurate and reproducible and could be used for routine anlysis of clonazepam in pharmaceutical preparations and serum samples.Keywords: Clonazepam, Ligand-exchange reaction, Kinetic spectrometry, Validation, Pharmaceutical preparation, Human seru

Levels of Major and Minor Elements in Some Commercial Fruit Juices Available in Serbia

Purpose: To evaluate the macro- and micro-nutrient elements of some commercially available fruit juices in Serbia.Methods: Inductively coupled plasma optical emission spectrometry (ICP-OES) technique was employed for determination of the major and minor elements in samples of two different types of fruit juices - clear and cloudy.Results: Among macro-nutrient elements, potassium (K) had the highest content of 230.17 μg/g in samples of multivitamine cloudy juice. The content of K was higher in cloudy fruit juices than in clear fruit juices. The content of iron, which is among the group of trace elements, ranged from 2.237 to 5.911 μg/g in clear juices and 3.55 to 10.05 μg/g in cloudy fruit juices. Other trace elements followed the descending order copper > zinc > nickel in terms of their content. The presence of aluminum and cadmium in the tested samples of fruit juices can be toxic since they have no nutritional value, and hence may be treated as potential contaminants in these beverages.Conclusion: All the tested juices had some nutritional value for human health and the juices could be use as an additional source of these elements. The content of aluminium and cadmium are below levels permitted by national regulations.Keywords: Elements, Fruit juice, Inductively-coupled plasma optical emission spectrometry

Fluid Particle Accelerations in Fully Developed Turbulence

The motion of fluid particles as they are pushed along erratic trajectories by fluctuating pressure gradients is fundamental to transport and mixing in turbulence. It is essential in cloud formation and atmospheric transport, processes in stirred chemical reactors and combustion systems, and in the industrial production of nanoparticles. The perspective of particle trajectories has been used successfully to describe mixing and transport in turbulence, but issues of fundamental importance remain unresolved. One such issue is the Heisenberg-Yaglom prediction of fluid particle accelerations, based on the 1941 scaling theory of Kolmogorov (K41). Here we report acceleration measurements using a detector adapted from high-energy physics to track particles in a laboratory water flow at Reynolds numbers up to 63,000. We find that universal K41 scaling of the acceleration variance is attained at high Reynolds numbers. Our data show strong intermittency---particles are observed with accelerations of up to 1,500 times the acceleration of gravity (40 times the root mean square value). Finally, we find that accelerations manifest the anisotropy of the large scale flow at all Reynolds numbers studied.Comment: 7 pages, 4 figure

A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA

T Follicular helper cells (TFH) are considered critical for B cell antibody response, and recent efforts have focused on promoting TFH in order to enhance vaccine efficacy. We studied the frequency and function of TFH in nasopharynx-associated lymphoid tissues (NALT) from children and adults, and its role in anti-influenza antibody response following stimulation by a live-attenuated influenza vaccine (LAIV) or an inactivated seasonal virus antigen (sH1N1). We further studied whether CpG-DNA promotes TFH and by which enhances anti-influenza response. We showed NALT from children aged 1.5-10 years contained abundant TFH, suggesting efficient priming of TFH during early childhood. Stimulation by LAIV induced a marked increase in TFH that correlated with a strong production of anti-hemagglutinin (HA) IgA/IgG/IgM antibodies in tonsillar cells. Stimulation by the inactivated sH1N1 antigen induced a small increase in TFH which was markedly enhanced by CpG-DNA, accompanied by enhanced anti-HA antibody responses. In B cell co-culture experiment, anti-HA responses were only seen in the presence of TFH, and addition of plasmacytoid dendritic cell to TFH-B cell co-culture enhanced the TFH-mediated antibody production following CpG-DNA and sH1N1 antigen stimulation. Induction of TFH differentiation from naïve T cells was also shown following the stimulation. Our results support a critical role of TFH in human mucosal anti-influenza antibody response. Use of an adjuvant such as CpG-DNA that has the capacity to promote TFH by which to enhance antigen-induced antibody responses in NALT tissue may have important implications for future vaccination strategies against respiratory pathogens

Reconstructions of deltaic environments from Holocene palynological records in the Volga delta, northern Caspian Sea

This article was made available through open access by the Brunel Open Access Publishing Fund.New palynological and ostracod data are presented from the Holocene Volga delta, obtained from short cores and surface samples collected in the Damchik region, near Astrakhan, Russian Federation in the northern Caspian Sea. Four phases of delta deposition are recognized and constrained by accelerated mass spectrometry (AMS) radiocarbon ages. Palynological records show that erosive channels, dunes (Baer hills) and inter-dune lakes were present during the period 11,500–8900 cal. BP at the time of the Mangyshlak Caspian lowstand. The period 8900–3770 cal. BP was characterized regionally by extensive steppe vegetation, with forest present at times with warmer, more humid climates, and with halophytic and xerophytic vegetation present at times of drought. The period 3770–2080 cal. BP was a time of active delta deposition, with forest or woodland close to the delta, indicating relatively warm and humid climates and variable Caspian Sea levels. From 2080 cal. BP to the present-day, aquatic pollen is frequent in highstand intervals and herbaceous pollen and fungal hyphae frequent in lowstand intervals. Soils and incised valley sediments are associated with the regional Derbent regression and may be time-equivalent with the ‘Medieval Warm Period’. Fungal spores are an indicator of erosional or aeolian processes, whereas fungal hyphae are associated with soil formation. Freshwater algae, ostracods and dinocysts indicate mainly freshwater conditions during the Holocene with minor brackish influences. Dinocysts present include Spiniferites cruciformis, Caspidinium rugosum, Impagidinium caspienense and Pterocysta cruciformis, the latter a new record for the Caspian Sea. The Holocene Volga delta is a partial analogue for the much larger oil and gas bearing Mio-Pliocene palaeo-Volga delta.Funding for the data collection and field work was provided from the following sources: 1 – IGCP-UNESCO 2003–2008 (Project 481 CASPAGE, Dating Caspian Sea Level Change); 2 – NWO, Netherlands Science Foundation and RFFI, Russian Science Foundation 2005–2008 (Programme: ‘VHR Seismic Stratigraphy and Paleoecology of the Holocene Volga Delta’); and 3 – BP Exploration (Caspian Sea) Sea Ltd. (Azeri-Chirag-Gunashli) 2005–2008 (‘Unravelling the Small-Scale Stratigraphy and Sediment Dynamics of the Modern Volga Delta Using VHR Marine Geophysics’). The palynological work was funded jointly by BP Exploration (Caspian Sea) Ltd., Delft University of Technology and KrA Stratigraphic Ltd. Ostracod analyses were funded by StrataData Ltd. and funding for two additional radiocarbon dates provided by Deltares