625 research outputs found

    Vortex-antivortex annihilation in mesoscopic superconductors with a central pinning center

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    In this work we solved the time-dependent Ginzburg-Landau equations, TDGL, to simulate two superconducting systems with different lateral sizes and with an antidot inserted in the center. Then, by cycling the external magnetic field, the creation and annihilation dynamics of a vortex-antivortex pair was studied as well as the range of temperatures for which such processes could occur. We verified that in the annihilation process both vortex and antivortex acquire an elongated format while an accelerated motion takes place.Comment: 4 pages, 5 figures, work presented in Vortex VII

    Functional differences between neurochemically defined populations of inhibitory interneurons in the rat spinal dorsal horn

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    In order to understand how nociceptive information is processed in the spinal dorsal horn we need to unravel the complex synaptic circuits involving interneurons, which constitute the vast majority of the neurons in laminae I–III. The main limitation has been the difficulty in defining functional populations among these cells. We have recently identified 4 nonoverlapping classes of inhibitory interneuron, defined by expression of galanin, neuropeptide Y (NPY), neuronal nitric oxide synthase (nNOS) and parvalbumin, in the rat spinal cord. In this study we demonstrated that these form distinct functional populations that differ in terms of sst2A receptor expression and in their responses to painful stimulation. The sst2A receptor was expressed by nearly all of the nNOS- and galanin-containing inhibitory interneurons but by few of those with NPY and none of the parvalbumin cells. Many galanin- and NPY-containing cells exhibited phosphorylated extracellular signal-regulated kinases (pERK) after mechanical, thermal or chemical noxious stimuli, but very few nNOS-containing cells expressed pERK after any of these stimuli. However, many nNOS-positive inhibitory interneurons up-regulated Fos after noxious thermal stimulation or injection of formalin, but not after capsaicin injection; nor did parvalbumin cells express either activity-dependent marker after any of these stimuli. These results suggest that interneurons belonging to the NPY, nNOS and galanin populations are involved in attenuating pain, and for NPY and nNOS cells this is likely to result from direct inhibition of nociceptive projection neurons. They also suggest that the nociceptive inputs to the nNOS cells differ from those to the galanin and NPY populations

    Grotta Romanelli (Southern Italy, Apulia). Legacies and issues in excavating a key site for the Pleistocene of the Mediterranean

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    Grotta Romanelli, located on the Adriatic coast of southern Apulia (Italy), is considered a key site for the Mediterranean Pleistocene for its archaeological and palaeontological contents. The site, discovered in 1874, was re-evaluated only in 1900, when P. E. Stasi realised that it contained the first evidence of the Palaeolithic in Italy. Starting in 1914, G. A. Blanc led a pioneering excavation campaign, for the first-time using scientific methods applied to systematic palaeontological and stratigraphical studies. Blanc proposed a stratigraphic framework for the cave. Different dating methods (C-14 and U/Th) were used to temporally constrain the deposits. The extensive studies of the cave and its contents were mostly published in journals with limited distribution and access, until the end of the 1970s, when the site became forgotten. In 2015, with the permission of the authorities, a new excavation campaign began, led by a team from Sapienza University of Rome in collaboration with IGAG CNR and other research institutions. The research team had to deal with the consequences of more than 40 years of inactivity in the field and the combined effect of erosion and legal, as well as illegal, excavations. In this paper, we provide a database of all the information published during the first 70 years of excavations and highlight the outstanding problems and contradictions between the chronological and geomorphological evidence, the features of the faunal assemblages and the limestone artefacts

    The Monumental UNESCO Site of Panamá Viejo: Investigation of the Masonry Mortars

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    The presented study illustrates the characterisation of several artificial materials (bedding, joint mortars, and plasters) belonging to the masonries of the UNESCO site of Panamá Viejo, located in Panama City (Panama). This monumental site represents the first Spanish settlement on the Pacific Coast, founded 500 years ago, in 1519. Through mineralogical and petrographic analyses of the collected samples, as stereomicroscope and polarized light microscopy (PLM) observations of bulk and thin sections, respectively, environmental scanning electron microscopy and micro-chemical investigations (ESEM-EDX) and X-Ray Powder diffraction (XRPD) analysis, it was possible to identify the composition of the materials utilized for the production of mortars and plasters, in addition to the determination of their state of conservation. Therefore, this work represents a substantial step for the preservation of the Panamá Viejo site, in order to support the selection of the most suitable restoration products, such as consolidants, protectives, etc., but also for choosing the most compatible materials for possible replacements/integrations in the masonries

    Anti-inflammatory and wound healing effects of an essential oils-based bioadhesive gel after oral mucosa biopsies: preliminary results

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    Post-operative management of patients receiving oral biopsy includes the control of edema, pain, infection, and re-epithelization at the surgical site. This clinical study investigates the topical use of a bioadhesive gel, containing essential oils, to promote wound healing and prevent post-operative pain and infection, avoiding the need for surgical suture and chlorhexidine applications. Ten patients, who needed to receive oral biopsies ( 646 mm in diameter) for the diagnosis of mucosal oral lesions, were enrolled. The bioadhesive gel successfully controlled the post-surgical pain; at 1-week follow-up visit, no signs of infection nor side effects were reported and the surgical sites were completely healed. The bioadhesive gel resulted in a very promising agent for the post-operative management of oral biopsy site, without the need for surgical suture and chlorhexidine applications

    Matching fields of a long superconducting film

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    We obtain the vortex configurations, the matching fields and the magnetization of a superconducting film with a finite cross section. The applied magnetic field is normal to this cross section, and we use London theory to calculate many of its properties, such as the local magnetic field, the free energy and the induction for the mixed state. Thus previous similar theoretical works, done for an infinitely long superconducting film, are recovered here, in the special limit of a very long cross section.Comment: Contains a REVTeX file and 4 figure

    Rupture Of Abdominal Aortic Aneurysm Due To Endograft Infection After Endovascular Aneurysm Repair (EVAR): A Case Report

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    Endograft infection is a rare event, with few reports in the literature. This report describes delayed infection of an aortic endoprosthesis that eventually resulted in abdominal aortic aneurysm (AAA) rupture. The procedure was performed in an angiographic suite. In the postoperative period the patient developed a central venous line infection. This appears to be the first recognized and reported case in which the infected aortic neck completely dilated due to the radial force of the stent graft

    Effective and selective extraction of quercetin from onion (Allium cepa l.) skin waste using water dilutions of acid-based deep eutectic solvents

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    Deep Eutectic Solvents (DESs) are experiencing growing interest as substitutes of polluting organic solvents for their low or absent toxicity and volatility. Moreover, they can be formed with natural bioavailable and biodegradable molecules; they are synthesized in absence of hazardous solvents. DESs are, inter alia, successfully used for the extraction/preconcentration of biofunctional molecules from complex vegetal matrices. Onion skin is a highly abundant waste material which represents a reservoir of molecules endowed with valuable biological properties such as quercetin and its glycosylated forms. An efficient extraction of these molecules from dry onion skin from “Dorata di Parma” cultivar was obtained with water dilution of acid-based DESs. Glycolic acid (with betaine 2/1 molar ratio and L-Proline 3/1 molar ratio as counterparts) and of p-toluensulphonic acid (with benzyltrimethylammonium methanesulfonate 1/1 molar ratio)-based DESs exhibited more than 3-fold higher extraction efficiency than methanol (14.79 μg/mL, 18.56 μg/mL, 14.83 μg/mL vs. 5.84 μg/mL, respectively). The extracted quercetin was also recovered efficaciously (81% of recovery) from the original extraction mixture. The proposed extraction protocol revealed to be green, efficacious and selective for the extraction of quercetin from onion skin and it could be useful for the development of other extraction procedures from other biological matrixes

    Variational method and duality in the 2D square Potts model

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    The ferromagnetic q-state Potts model on a square lattice is analyzed, for q>4, through an elaborate version of the operatorial variational method. In the variational approach proposed in the paper, the duality relations are exactly satisfied, involving at a more fundamental level, a duality relationship between variational parameters. Besides some exact predictions, the approach is very effective in the numerical estimates over the whole range of temperature and can be systematically improved.Comment: 20 pages, 5 EPS figure
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