Reconstruction of late Quaternary marine and terrestrial environmental conditions of Northwest Africa and Southeast Australia A multiple organic proxy study using marine sediments

NW Africa and SE Australia are regions which are particularly vulnerable to climate change. In this thesis, organic proxies are used from marine sediment cores to reconstruct past environmental conditions from these areas. In sediments from NW Africa, the UK'37 showed an efficient proxy for sea surface temperature (SST) reconstruction, while the TEXH86 reconstructed thermocline temperatures. The UK'37 and TEXH86 records for the last 192 ka showed that periods of reduced AMOC coincide with a reduction in the vertical temperature gradient. Thus, variations in AMOC strength is a driver of the thermocline structure in the tropical Atlantic. Three independent organic proxies (UK’37,TEXH86 and LDI) were used to reconstruct SSTs for the last 135 ka in sediments from offshore SE Australia. Comparison with SST estimates based on foraminiferal assemblages shows that LDI temperatures compared well with the temperature of the warmest month, TEXH86 with the temperature of the coolest month and UK’37 with mean annual temperature. Thus, the application of these 3 proxies together at this area enables the reconstruction of SST variations from different seasons. Accumulation rates and concentrations of biomarkers from marine plankton classes were used to examine the changes in productivity at the above mentioned sites during the late Quaternary. In NW Africa, a positive correlation was observed between TOC content, productivity proxies (for dinoflagellates, eustigmatophytes, haptophytes) and the sedimentary Fe, in particular during periods of high aridity on the continent. Thus, the productivity in this area is considerably influenced by the fertilization effect of the Sahara dust, while in SE Australia, Proboscia diatom productivity seems to be controlled by the transport of silicic acid to this area as increases in its productivity matched increased diatom productivity observed at some sites of the tropical equatorial Pacific. To assess changes in the vegetation of NW Africa and SE Australia, the d13C of the n-alkanes from plant leaf waxes were analysed. Sediments from the NW Africa reveal three periods (early Holocene, 50–45 and 120–110 ka) during the past 192 ka when the central Sahara/Sahel contained a higher percentage of C3 plants, indicating wetter conditions than at present. A remarkably close correlation between d13C of benthic foraminifera and n-alkanes indicates a connection between variability in AMOC strength and vegetation type in the Sahara/Sahel region. The n-alkane d13C record from SE Australia reveals an extensive period (68-31ka) of high C4 plant abundance that is punctuated by a sharp increase in C3 vegetation at ~43 ka. This sharp increase in C3 vegetation lasts ~5 ka and is characterized by increased levels of biomass burning. Thus, this vegetation change was likely caused by increased burning events and/or by reduced herbivory as it follows the main period of the late Quaternary megafauna extinction in Australia. This thesis demonstrates the benefit of applying multiple organic proxies on marine sediments to assess marine and terrestrial paleoenvironmental changes and it has thereby provided new insights in the cause and effect of environmental changes in marine and continental areas of NW Africa and SE Australia

Projetos De Modernidade: Autoritarismo, Eugenia E Racismo No Brasil Do Século Xx

This article takes as its starting point the idea of modernity in Brazil and its deployment in Brazilian society by means of an authoritarian project that values the “whitening” of the country. In this sense, we will discuss, albeit briefly, the concept of modernity. To explain the phenomenon of modernity through authoritarianism, we will focus on the concept of authoritarian nationalism. The racial issue is the focal point of the discussion, so we will present a synthesis of Brazilian social thought from the mid-19th century to the 1930s, in order to deal with the idea of eugenics in Brazil and the reception of European racist theories in that country. © 2016, Universidad de los Andes, Bogota Colombia. All rights reserved.201658283

Annotated Checklist Of Echinoderms From Araçá Bay, Southeastern Brazil

We present a species list of echinoderms from Araçá Bay, state of São Paulo. Altogether, 863 specimens belonging to 25 species, 19 genera, and 13 families were exhaustively collected during three years in consolidated and non-consolidated substrate. Ophiuroidea was the most representative taxon with 16 species, follow by Asteroidea with four species, Echinoidea with three, and Holothuroidea with two species. The brittle stars Amphiura kinbergi and Ophiothela cf. mirabilis are new records for Araçá Bay. We confirm that Araçá Bay is one of the best known area of echinoderm diversity in Brazil considering that the perimeter (3 km) of the bay corresponds to only 0.03% of the Brazilian coastline (8500 km). This work complements the knowledge of Araçá Bay biodiversity and supports future interventions, management and maintaining the diversity of this wonderful group of marine animals. © 2016 Check List and Authors.12

Peat properties, dominant vegetation type and microbial community structure in a tropical peatland

Tropical peatlands are an important carbon store and source of greenhouse gases, but the microbial component, particularly community structure, remains poorly understood. While microbial communities vary between tropical peatland land uses, and with biogeochemical gradients, it is unclear if their structure varies at smaller spatial scales as has been established for a variety of peat properties. We assessed the abundances of PLFAs and GDGTs, two membrane spanning lipid biomarkers in bacteria and fungi, and bacteria and archaea, respectively, to characterise peat microbial communities under two dominant and contrasting plant species, Campnosperma panamensis (a broadleaved evergreen tree), and Raphia taedigera (a canopy palm), in a Panamanian tropical peatland. The plant communities supported similar microbial communities dominated by Gram negative bacteria (38.9–39.8%), with smaller but significant fungal and archaeal communities. The abundance of specific microbial groups, as well as the ratio of caldarchaeol:crenarchaeol, isoGDGT: brGDGTs and fungi:bacteria were linearly related to gravimetric moisture content, redox potential, pH and organic matter content indicating their role in regulating microbial community structure. These results suggest that tropical peatlands can exhibit significant variability in microbial community abundance even at small spatial scales, driven by both peat botanical origin and localised differences in specific peat properties

Family resemblances in action: an introduction to religio-political activism in Southern Africa

The introduction to this special issue argues that in many countries in southern Africa a new phase in the entanglement between the religious and the political has set in. Increasingly, activists in political fields are borrowing from religious registers of discourse and practice, while conversely, activists in the religious domain are adopting discourses and practices originating in the political domain. We suggest that this religiopolitical activism is simultaneously the product of a climate of profound social change and an important transformative force within it. In order to do justice to the complex dynamics of southern African religiopolitical activism in its manifold manifestations, we draw on the concept of ‘family resemblances’. This allows us to examine how the boundaries between religious and political registers are made the object of situated social negotiations. The family resemblances explored in this special issue range from religiopolitical activists’ habitus and their communication strategies via religious leaders’ self-positionings in relation to the political, to the creation of specific religiopolitical spaces.ASC – Publicaties niet-programma gebonde

Frequency and damping of hydrodynamic modes in a trapped Bose-condensed gas

Recently it was shown that the Landau-Khalatnikov two-fluid hydrodynamics describes the collision-dominated region of a trapped Bose condensate interacting with a thermal cloud. We use these equations to discuss the low frequency hydrodynamic collective modes in a trapped Bose gas at finite temperatures. We derive a variational expressions based on these equations for both the frequency and damping of collective modes. A new feature is our use of frequency-dependent transport coefficients, which produce a natural cutoff by eliminating the collisionless low-density tail of the thermal cloud. Above the superfluid transition, our expression for the damping in trapped inhomogeneous gases is analogous to the result first obtained by Landau and Lifshitz for uniform classical fluids. We also use the moment method to discuss the crossover from the collisionless to the hydrodynamic region. Recent data for the monopole-quadrupole mode in the hydrodynamic region of a trapped gas of metastable $^4$He is discussed. We also present calculations for the damping of the analogous $m=0$ monopole-quadrupole condensate mode in the superfluid phase.Comment: 22 pages, 10 figures, submitted to Physical Review

Theotonio dos Santos (1936-2018), the revolutionary intellectual who pioneered dependency theory

This article analyzes the origins and development of the dependency theory through the life and work of Theotonio Dos Santos. His formative years at the academy and his early political activism in Brazil are examined, particularly, his time at the University of Brasilia with Vania Bambirra, Ruy Mauro Marini and André Gunder Frank ("the quartet"). This is followed by a discussion about their years of exile in Chile where the quartet regrouped at the Center for Socio-Economic Studies (ceso) of the University of Chile, and where they wrote their founding texts on dependency theory. Chile provided fertile ground for the development of this theory due to its intellectual climate, institutionality, and the country's political transformations in the late 1960s and early 1970s. The military overthrow of the Allende government on that fateful September 11th, 1973 forced the quartet once again into exile. The article continues with an analysis of Dos Santos' writings during his exile in Mexico and then back in Brazil. During this period he became involved with world system theory which culminated in the publication of his extensive trilogy on the contemporary crisis of capitalism and social theory

Beneficial effects of the activation of the Angiotensin-(1-7) MAS receptor in a murine model of adriamycin-induced nephropathy

Angiotensin-(1-7) [Ang-(1-7)] is a biologically active heptapeptide that may counterbalance the physiological actions of angiotensin II (Ang II) within the renin-angiotensin system (RAS). Here, we evaluated whether activation of the Mas receptor with the oral agonist, AVE 0991, would have renoprotective effects in a model of adriamycin (ADR)-induced nephropathy. We also evaluated whether the Mas receptor contributed for the protective effects of treatment with AT1 receptor blockers. ADR (10 mg/kg) induced significant renal injury and dysfunction that was maximal at day 14 after injection. Treatment with the Mas receptor agonist AVE 0991 improved renal function parameters, reduced urinary protein loss and attenuated histological changes. Renoprotection was associated with reduction in urinary levels of TGF-{beta}. Similar renoprotection was observed after treatment with the AT1 receptor antagonist, Losartan. AT1 and Mas receptor mRNA levels dropped after ADR administration and treatment with losartan reestablished the expression of Mas receptor and increased the expression of ACE2. ADR-induced nephropathy was similar in wild type (Mas(+/+)) and Mas knockout (Mas (-/-)) mice, suggesting there was no endogenous role for Mas receptor activation. However, treatment with Losartan was able to reduce renal injury only in Mas(+/+) , but not in Mas (-/-) mice. Therefore, these findings suggest that exogenous activation of the Mas receptor protects from ADR-induced nephropathy and contributes to the beneficial effects of AT1 receptor blockade. Medications which target specifically the ACE2/Ang-(1-7)/Mas axis may offer new therapeutic opportunities to treat human nephropathies

Cofactors revisited - Predicting the impact of flavoprotein-related diseases on a genome scale

Flavin adenine dinucleotide (FAD) and its precursor flavin mononucleotide (FMN) are redox cofactors that are required for the activity of more than hundred human enzymes. Mutations in the genes encoding these proteins cause severe phenotypes, including a lack of energy supply and accumulation of toxic intermediates. Ideally, patients should be diagnosed before they show symptoms so that treatment and/or preventive care can start immediately. This can be achieved by standardized newborn screening tests. However, many of the flavin-related diseases lack appropriate biomarker profiles. Genome-scale metabolic models can aid in biomarker research by predicting altered profiles of potential biomarkers. Unfortunately, current models, including the most recent human metabolic reconstructions Recon and HMR, typically treat enzyme-bound flavins incorrectly as free metabolites. This in turn leads to artificial degrees of freedom in pathways that are strictly coupled. Here, we present a reconstruction of human metabolism with a curated and extended flavoproteome. To illustrate the functional consequences, we show that simulations with the curated model - unlike simulations with earlier Recon versions - correctly predict the metabolic impact of multiple-acyl-CoA-dehydrogenase deficiency as well as of systemic flavin-depletion. Moreover, simulations with the new model allowed us to identify a larger number of biomarkers in flavoproteome-related diseases, without loss of accuracy. We conclude that adequate inclusion of cofactors in constraint-based modelling contributes to higher precision in computational predictions.FWN – Publicaties zonder aanstelling Universiteit Leide