A two-channel Molecular dosimeter for the optical detection of copper(II)

A cyclam-like macrocycle with an integrated push-pull chromophore selectively detects Cu2+ inclusion through both orange-to-yellow colour change and quenching of the green fluorescence

Multifunctional and Durable Coatings for Stone Protection Based on Gd-Doped Nanocomposites

The development of nanocomposite materials with multifunctional protective features is an urgent need in many fields. However, few works have studied the durability of these materials. Even though TiO2 nanoparticles have been extensively applied for self-cleaning effect, it displays a weak activity under visible light. Hence, in this study, pure and Gd-doped TiO2 nanoparticles (molar ratios of doping ions/Ti are 0.1 and 1) were synthesised, characterised, and then mixed with polydimethylsiloxane (PDMS), used as a binder, in order to produce a homogenised thin film on a very porous stone substrate. To our knowledge, Gd-doped TiO2/PDMS protective coatings are studied for the first time for application on historic structures. The protective coatings developed in this work are intended to reduce the surface wettability of the stone and protect the historic stones from dye pollution and microorganism colonisation. Moreover, in this study, the durability of the developed nanocomposite was deeply studied to evaluate the stability of the coatings. Results confirmed that samples treated with the lowest concentrations of Gd ions (0.1 mol%) showed acceptable chromatic variations, a good repellent feature, acceptable water vapour permeability, good durability, the highest self-cleaning activity, and good inhibitory behaviour against microbial colonisation

Light Emitting Molecular Devices Based on Transition Metals

Multicomponent systems have been designed, which are able to perform defined functions related to light emission and quenching. The desired function can be switched ON/OFF by the operator through a chemical input, either a change of pH or a variation of the redox potential. Transition metals (e.g. Ni(II), Cu(II)) are key constituents within the considered systems, playing a distinctive architectural role and favouring electron transfer processes

The use and beauty of ultra-high-resolution seismic reflection imaging in Late Quaternary marine volcaniclastic settings, Bay of Naples, Italy

A Nápolyi-öbölben felvett ultra nagy felbontású egycsatornás (IKB-Seistec™) reflexiós szeizmikus szelvények korábbi geológiai és geofizikai vizsgálatok eredményeivel együtt kivételes, eddig soha nem látott felbontású szeizmikus leképezését nyújtják a Flegrei-mezők és a Somma-Vezúv felszín alá süllyedt késő-pleisztocén–holocén rétegtani felépí - tésének. A szeizmikus szelvényeken látott geometria és gravitációs magvevővel nyert üledékek adatainak összevetéséből Campania partközeli kontinentális talapzatán számos olyan üledékes és vulkáni szerkezet, valamint hidrotermális jelenség került leképezésre, melyek a legutolsó glaciális maximum (kb. 18 000 év) óta keletkeztek. A Pozzuoli-öbölben mért Seistec szelvények jól mutatják a beomlott kaldera gyűrűs vetőjét, a kb. 15 ezer éves Nápolyi Sárga Tufa (NYT) lerakódáshoz vezető kitöréskor felújuló boltozatot, és alátámasztják a deformáció későnegyedidőszaki korára és stílusára vonatkozó hipotéziseket. A szeizmikus szelvényeken látható a NYT rétegeinek töréses szerkezete, valamint hidrotermális fluidum-feláramlások és vulkáni/szubvulkáni intrúziók a gyűrűs vetők mentén. A Somma-Vezúv rétegvulkán előterében a kontinentális talapzat felett mért szeizmikus szelvények leképezték a Vezúv i.sz. 79-es kitörésekor Herculaneum városát elpusztító piroklaszt-ár tengervízbe érésekor keletkező, gravitációsan összeomló homokhullámok szerkezetét is. A Somma-Vezúv és a Pozzuoli-öböl közti, buckás felszínű Banco della Montagna területén mért szelvények és fúrómagok vulkanoklasztos diapírok sorát tárták fel. Ezeket a konszolidálatlan horzsakőből álló testeket a fluidum - feláramlás és aktív kigázosodás hatására kialakult mélybeli túlnyomás hozta fel a tengerfenékre.Very high-resolution, single channel (IKB-Seistec™) reflection seizmic profiles acquired in the Bay of Naples, com - plemented with geological and geophysical data from the literature, provide unprecedented, superb seismic imaging of the latest Pleistocene–Holocene stratigraphic architecture of the submerged sectors Campi Flegrei and Somma-Vesuvius volcanic districts. Seismic profiles were calibrated by gravity core data and document a range of depositional systems, volcanic structures and hydrothermal features that evolved after the onset of the Last Glacial Maximum (~ 18 ka BP) over the continental shelf on the Campania coastal zone. Seistec profiles from the Pozzuoli Bay yield high-resolution images of the shallow structure of the collapse caldera-ring fault — resurgent dome system associated with the eruption of the Neapolitan Yellow Tuff (NYT) (ca 15 ka) and support a working hypothesis to assess the timing and the styles of deformation of the NYT resurgent structure throughout the latest Quaternary. Seismic images also revealed the nature of the fragile deformation of strata along the NYT ring fault system and the occurrence of hydrothermal fluids and volcanic/subvolcanic intrusions ascending along the ring fault zone. Seismic data acquired over the continental shelf off the Somma-Vesuvius stratovolcano, display evidence of gravit - ational instability of wavy bedforms representing the submarine prosecution of pyroclastic flows originated from the Vesuvius during the eruption that destroyed the Roman city of Herculaneum in 79 CE. At the Banco della Montagna, a hummocky seafloor knoll located between the Somma-Vesuvius and the Pozzuoli Bay, seismic profiles and gravity core data revealed the occurrence of a field of volcaniclastic diapirs formed by the dragging and rising up of unconsolidated pumice, as a consequence of fluid overpressure at depth associated with active degassing and fluid venting at the seafloor

Social movements, the European crisis, and EU political opportunities

Social movements in the wake of the financial crisis have shifted from the counter-summits and world social forums of the global justice movement to the camps of the anti-austerity mobilizations, and from a clear focus on building ‘another Europe’ to more domestically embedded issues. Among other reasons, this turn away from the EU can be linked to contracting political opportunities for social justice movements at the European level. This article addresses the closure of opportunities at the EU level for the work of social movement groups campaigning on specific EU policies. We reflect on the complexity of the EU’s political opportunity structure prior to the financial crisis, before examining changes to the EU’s architecture effected through responses to the crises and outlining arguments on how EU level opportunities around socio-economic issues in particular have shrunk as a result. We then show how the perception of other political opportunities at the EU level is affected by the austerity response by drawing on campaigns that sought to exploit new opportunities included in the Lisbon Treaty and designed to increase citizens’ input. Opportunities introduced by changes made in the Lisbon Treaty are perceived through the prism of contracted opportunities flowing from power shifts caused by the response to the financial crisis

Vaccination against SARS-CoV-2 in pregnancy during the Omicron wave: the prospective cohort study of the Italian obstetric surveillance system

Objectives: Evidence on the effects of the SARS-CoV-2 Omicron variant on vaccinated and unvaccinated pregnant women is sparse. This study aimed to compare maternal and perinatal outcomes of women infected with SARS-CoV-2 during the Omicron wave in Italy, according to their vaccine protection.Methods: This national prospective cohort study enrolled pregnant women with a positive SARS-CoV-2 nasopharyngeal swab within 7 days of hospital admission between 1 January and 31 May, 2022. Women who received at least one dose of vaccine during pregnancy and those who completed the vaccine cycle with the first booster were considered protected against moderate or severe COVID-19 (MSCD). A multivariable logistic regression model evaluated the association between vaccine protection and disease severity. Maternal age, educational level, citizenship, area of birth, previous comorbidities, and obesity were analysed as potential risk factors. Results: MSCD was rare (41/2147, 1.9%; 95% CI, 1.4-2.6), and the odds of developing it were significantly higher among unprotected women (OR, 2.78; 95% CI, 1.39-5.57). Compared with protected women (n = 1069), the unprotected (n = 1078) were more often younger, with lower educational degrees, and foreigners. A higher probability of MSCD was found among women with previous comorbidities (OR, 2.86; 95% CI, 1.34-6.12) and those born in Asian countries (OR, 3.05; 95% CI, 1.23-7.56). The percentage of preterm birth was higher among women with MSCD compared with milder cases (32.0% [8/25] versus 8.4% [161/1917], p < 0.001) as well as the percentage of caesarean section (52.0% [13/25] versus 31.6% [606/1919], p 0.029). Discussion: Although severe maternal and perinatal outcomes were rare, their prevalence was significantly higher among women without vaccine protection. Vaccination during pregnancy has the potential to protect both the mother and the baby, and it is therefore strongly recommended. Edoardo Corsi Decenti, Clin Microbiol Infect 2023;29:772 (c) 2023 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved

Perinatal care in SARS-CoV-2 infected women: the lesson learnt from a national prospective cohort study during the pandemic in Italy

Background: Despite the growing importance given to ensuring high-quality childbirth, perinatal good practices have been rapidly disrupted by SARS-CoV-2 pandemic. This study aimed at describing the childbirth care provided to infected women during two years of COVID-19 emergency in Italy. Methods: A prospective cohort study enrolling all women who gave birth with a confirmed SARS-CoV-2 infection within 7 days from hospital admission in the 218 maternity units active in Italy during the periods February 25, 2020-June 30, 2021, and January 1-May 31, 2022. Perinatal care was assessed by evaluating the prevalence of the following indicators during the pandemic: presence of a labour companion; skin-to-skin; no mother-child separation at birth; rooming-in; breastfeeding. Logistic regression models including women' socio-demographic, obstetric and medical characteristics, were used to assess the association between the adherence to perinatal practices and different pandemic phases. Results: During the study period, 5,360 SARS-CoV-2 positive women were enrolled. Overall, among those who had a vaginal delivery (n = 3,574; 66.8%), 37.5% had a labour companion, 70.5% of newborns were not separated from their mothers at birth, 88.1% were roomed-in, and 88.0% breastfed. These four indicators showed similar variations in the study period with a negative peak between September 2020 and January 2021 and a gradual increase during the Alpha and Omicron waves. Skin-to-skin (mean value 66.2%) had its lowest level at the beginning of the pandemic and gradually increased throughout the study period. Among women who had a caesarean section (n = 1,777; 33.2%), all the indicators showed notably worse outcomes with similar variations in the study period. Multiple logistic regression analyses confirm the observed variations during the pandemic and show a lower adherence to good practices in southern regions and in maternity units with a higher annual number of births. Conclusions: Despite the rising trend in the studied indicators, we observed concerning substandard childbirth care during the SARS-CoV-2 pandemic. Continued efforts are necessary to underscore the significance of the experience of care as a vital component in enhancing the quality of family-centred care policies

A roadmap for amphibious drilling at the Campi Flegrei caldera: insights from a MagellanPlus workshop

Large calderas are among the Earth's major volcanic features. They are associated with large magma reservoirs and elevated geothermal gradients. Caldera-forming eruptions result from the withdrawal and collapse of the magma chambers and produce large-volume pyroclastic deposits and later-stage deformation related to post-caldera resurgence and volcanism. Unrest episodes are not always followed by an eruption; however, every eruption is preceded by unrest. The Campi Flegrei caldera (CFc), located along the eastern Tyrrhenian coastline in southern Italy, is close to the densely populated area of Naples. It is one of the most dangerous volcanoes on Earth and represents a key example of an active, resurgent caldera. It has been traditionally interpreted as a nested caldera formed by collapses during the 100–200 km3 Campanian Ignimbrite (CI) eruption at ∼39 ka and the 40 km3 eruption of the Neapolitan Yellow Tuff (NYT) at ∼15 ka. Recent studies have suggested that the CI may instead have been fed by a fissure eruption from the Campanian Plain, north of Campi Flegrei. A MagellanPlus workshop was held in Naples, Italy, on 25–28 February 2017 to explore the potential of the CFc as target for an amphibious drilling project within the International Ocean Discovery Program (IODP) and the International Continental Drilling Program (ICDP). It was agreed that Campi Flegrei is an ideal site to investigate the mechanisms of caldera formation and associated post-caldera dynamics and to analyze the still poorly understood interplay between hydrothermal and magmatic processes. A coordinated onshore–offshore drilling strategy has been developed to reconstruct the structure and evolution of Campi Flegrei and to investigate volcanic precursors by examining (a) the succession of volcanic and hydrothermal products and related processes, (b) the inner structure of the caldera resurgence, (c) the physical, chemical, and biological characteristics of the hydrothermal system and offshore sediments, and (d) the geological expression of the phreatic and hydromagmatic eruptions, hydrothermal degassing, sedimentary structures, and other records of these phenomena. The deployment of a multiparametric in situ monitoring system at depth will enable near-real-time tracking of changes in the magma reservoir and hydrothermal system

Acute Delta Hepatitis in Italy spanning three decades (1991–2019): Evidence for the effectiveness of the hepatitis B vaccination campaign

Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p &lt; .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p &lt; .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come