745 research outputs found
Challenges in lifestyle and community interventions research; a call for innovation
Earlier this year the BMC portfolio was enriched by a new journal BMC Obesity. Here, we present the aims and objectives of the section on Lifestyle and Community Interventions. Innovative research is needed. Preventing or managing obesity requires addressing different determinants across multiple levels where diverse levers and stakeholders can play a critical role. Interactions of these determinants within and between systems need to be studied. How to leverage, manage and measure this complexity underlies the innovation that is needed in the next generation of obesity interventions. The ambition of the Lifestyle and Community Interventions section is to provide a space for innovative research, including research that falls outside the traditional comfort zone. We welcome studies of heterogeneous designs, including those of qualitative, quantitative, mixed and systems methodologies. Studies of interest include not only outcomes research of interventions but also process evaluation, cost-effectiveness or cost-benefit analysis, and implementation and dissemination research. Innovations that integrate diverse intervention levers or combine primary and secondary levels of prevention are particularly encouraged. The general aim of BMC Obesity’s Lifestyle and Community Interventions section is to advance our ability to decide on what combinations of approaches will be required to effectively and equitably prevent obesity
Low temperature properties of holographic condensates
In the current work we study various models of holographic superconductors at
low temperature. Generically the zero temperature limit of those models are
solitonic solution with a zero sized horizon. Here we generalized simple
version of those zero temperature solutions to small but non-zero temperature
T. We confine ourselves to cases where near horizon geometry is AdS^4. At a
non-zero temperature a small horizon would form deep inside this AdS^4 which
does not disturb the UV physics. The resulting geometry may be matched with the
zero temperature solution at an intermediate length scale. We understand this
matching from separation of scales by setting up a perturbative expansion in
gauge potential. We have a better analytic control in abelian case and
quantities may be expressed in terms of hypergeometric function. From this we
calculate low temperature behavior of various quatities like entropy, charge
density and specific heat etc. We also calculate various energy gaps associated
with p-wave holographic superconductor to understand the underlying pairing
mechanism. The result deviates significantly from the corresponding weak
coupling BCS counterpart.Comment: 17 Page
The Rich Structure of Gauss-Bonnet Holographic Superconductors
We study fully backreacting, Gauss-Bonnet (GB) holographic superconductors in
5 bulk spacetime dimensions. We explore the system's dependence on the scalar
mass for both positive and negative GB coupling, . We find that when
the mass approaches the Breitenlohner-Freedman (BF) bound and
the effect of backreaction is to increase the
critical temperature, , of the system: the opposite of its effect in the
rest of parameter space. We also find that reducing below zero
increases and that the effect of backreaction is diminished. We study the
zero temperature limit, proving that this system does not permit regular
solutions for a non-trivial, tachyonic scalar field and constrain possible
solutions for fields with positive masses. We investigate singular, zero
temperature solutions in the Einstein limit but find them to be incompatible
with the concept of GB gravity being a perturbative expansion of Einstein
gravity. We study the conductivity of the system, finding that the inclusion of
backreaction hinders the development of poles in the conductivity that are
associated with quasi-normal modes approaching the real axis from elsewhere in
the complex plane.Comment: 26 pages, 11 figures, V3, Added discussion of non-tachyonic scalars,
alterations to figures and tex
Evaluation of pcr, culture and serology for the dianosis of chlamydia pneumoniae respiratory infections
Holographic phase transition from dyons in an AdS black hole background
We construct a dyon solution for a Yang-Mills-Higgs theory in a 4 dimensional
Schwarzschild-anti-de Sitter black hole background with temperature T. We then
apply the AdS/CFT correspondence to describe the strong coupling regime of a
2+1 quantum field theory which undergoes a phase transition exhibiting the
condensation of a composite charge operator below a critical temperature .Comment: 19 pages, 7 figures. Minor corrections, references added. Version
published in JHEP
Evaluation of pcr, culture and serology for the dianosis of chlamydia pneumoniae respiratory infections
Lifshitz-like space-time from intersecting branes in string/M theory
We construct 1/4 BPS, threshold F-D bound states (with )
of type II string theories by applying S- and T-dualities to the D1-D5 system
of type IIB string theory. These are different from the known 1/2 BPS,
non-threshold F-D bound states. The near horizon limits of these solutions
yield Lifshitz-like space-times with varying dynamical critical exponent
, for , along with the hyperscaling violation exponent
, showing how Lifshitz-like space-time can be
obtained from string theory. The dilatons are in general non-constant (except
for ). We discuss the holographic RG flows and the phase structures of
these solutions. For , we do not get a Lifshitz-like space-time, but the
near horizon limit in this case leads to an AdS space.Comment: 20 pages, no figure, v2: proper identification of hyperscaling
violation exponent has been made, abstract and the text has been changed
accordingly, note added, v3: minor changes, refs added, version to appear in
JHE
Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies
BACKGROUND: Altered regulation of extracellular matrix (ECM) composition by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) may contribute to arterial stiffening. We investigated associations between circulating MMP-1, -2, -3, -9, -10 and TIMP-1, and carotid-femoral pulse wave velocity (cfPWV) and pulse pressure (PP), as markers of arterial stiffness in type 1 diabetic patients.
METHODS: Individuals with type 1 diabetes from three different cohorts were included in this study: EURODIAB Prospective Complications study (n = 509), LEACE (n = 370) and PROFIL (n = 638). Linear regression analyses were used to investigate cross-sectional associations between circulating levels of MMP-1, -2, -3, -9, -10, and TIMP-1 and cfPWV (n = 614) as well as office PP (n = 1517). Data on 24-h brachial and 24-h central PP were available in 638 individuals from PROFIL. Analyses were adjusted for age, sex, duration of diabetes, HbA1c, mean arterial pressure (MAP), and eGFR, and additionally for other cardiovascular risk factors and presence of vascular complications.
RESULTS: After adjustment for potential confounders and presence of vascular complications, circulating MMP-3 was associated with cfPWV [β per 1 SD higher lnMMP3 0.29 m/s (0.02; 0.55)]. In addition, brachial and central 24-h PP measurements in PROFIL were significantly associated with MMP-2 [(1.40 (0.47:2.33) and 1.43 (0.63:2.23)]. Pooled data analysis showed significant associations of circulating levels of MMP-1 and MMP-2 with office PP [β per 1 SD higher lnMMP-1 and lnMMP-2 = − 0.83 mmHg (95% CI − 1.50; − 0.16) and = 1.33 mmHg (0.55; 2.10), respectively].
CONCLUSIONS: MMPs-1, -2, and -3 are independently associated with markers of arterial stiffening in patients with type 1 diabetes and may become therapeutic targets
p-wave Holographic Superconductors and five-dimensional gauged Supergravity
We explore five-dimensional and
SO(6) gauged supergravities as frameworks for condensed matter applications.
These theories contain charged (dilatonic) black holes and 2-forms which have
non-trivial quantum numbers with respect to U(1) subgroups of SO(6). A question
of interest is whether they also contain black holes with two-form hair with
the required asymptotic to give rise to holographic superconductivity. We first
consider the case, which contains a complex two-form potential
which has U(1) charge . We find that a slight
generalization, where the two-form potential has an arbitrary charge , leads
to a five-dimensional model that exhibits second-order superconducting
transitions of p-wave type where the role of order parameter is played by
, provided . We identify the operator that condenses
in the dual CFT, which is closely related to Super Yang-Mills
theory with chemical potentials. Similar phase transitions between R-charged
black holes and black holes with 2-form hair are found in a generalized version
of the gauged supergravity Lagrangian where the two-forms have
charge .Comment: 35 pages, 14 figure
Holographic Superconductors
A holographic model of superconductors based on the action proposed by
Benini, Herzog, and Yarom [arXiv:1006.0731] is studied. This model has a
charged spin two field in an AdS black hole spacetime. Working in the probe
limit, the normalizable solution of the spin two field in the bulk gives rise
to a superconducting order parameter at the boundary of the AdS. We
calculate the fermion spectral function in this\ superconducting background and
confirm the existence of fermi arcs for non-vanishing Majorana couplings. By
changing the relative strength of the and condensations, the
position and the size of the fermi arcs are changed. When , the
spectrum becomes isotropic and the spectral function is s-wave like. By
changing the fermion mass, the fermi momentum is changed. We also calculate the
conductivity for these holographic superconductors where time reversal
symmetry has been broken spontaneously. A non-vanishing Hall conductivity is
obtained even without an external magnetic field.Comment: 24 pages,17 figures, Add more discussions on hall conductivity, two
new figures, Matched with published versio
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