Bayesian modelling reveals differences in long-term trends in the harvest of native and introduced species by recreational hunters in Australia

Context: Little is known about wildlife harvesting by licensed recreational hunters in Australia, where both native and introduced species are hunted. It is important to understand harvest trends to assess sustainability for native species and implications for population control of introduced species. Aim: The aim of this study was to analyse trends in hunter participation, activity and efficiency, and wildlife harvest, including effects of climate, in Victoria, Australia, for three game species groups: introduced deer, native waterfowl (ducks) and one native grassland species, stubble quail (Coturnix pectoralis). Methods: Telephone surveys of a random sample of licenced Victorian hunters were performed annually from 2009 to 2019. Hunters were asked to quantify their hunting effort and the number of animals harvested. The respondents’ answers were analysed to estimate measures of hunter success, activity and efficiency. Bayesian modelling was applied to these data, accounting for changes over time, differences between survey periods for all licence types, and random effects for over-dispersion. The effect of climate on game bird hunter activity and harvest was estimated, as measured by the El Niño-Southern Oscillation (ENSO). Results: Over 11 years, annual deer harvest (all species) increased exponentially, at a mean annual rate of 17% (95% credible interval: 14–21%), and the number of deer hunters increased at 8% (5–11%). In contrast, for ducks and stubble quail, hunter numbers remained relatively unchanged, with no evidence of consistent change to total harvests over time, unrelated to changes in environmental conditions or regulations. The annual duck harvest was influenced by ENSO and hunting regulations. The annual stubble quail harvest exhibited ‘boom-and-bust’ dynamics, with an exceptionally large harvest immediately after a La Niña season. Conclusions: Long-term monitoring of harvest trends in south-eastern Australia revealed stark differences between introduced deer and native birds: harvest of deer increased rapidly whereas equivalent rates for game birds were either stable or declining. Seasonal effects had a strong influence on game bird harvest. Environmental and regulatory conditions were influential for harvest outcomes for ducks and stubble quail. Implications: This study filled a key knowledge gap around managing harvesting of game species, but increased scrutiny is warranted in this field

A cyclical period variation detected in the updated orbital period analysis of TV Columbae

The two CCD photometries of the intermediate polar TV Columbae are made for obtaining the two updated eclipse timings with high precision. There is an interval time \sim 17yr since the last mid-eclipse time observed in 1991. Thus, the new mid-eclipse times can offer an opportunity to check the previous orbital ephemerides. A calculation indicates that the orbital ephemeris derived by Augusteijn et al. (1994) should be corrected. Based on the proper linear ephemeris (Hellier, 1993), the new orbital period analysis suggests a cyclical period variation in the O-C diagram of TV Columbae. Using Applegate's mechanism to explain the periodic oscillation in O-C diagram, the required energy is larger than that a M0-type star can afford over a complete variation period \sim 31.0(\pm 3.0)yr. Thus, the light travel-time effect indicates that the tertiary component in TV Columbae may be a dwarf with a low mass, which is near the mass lower limit \sim 0.08Msun as long as the inclination of the third body high enough.Comment: 10 pages, 5 figure

Identification and validation of novel biomarkers and therapeutics for pulpitis using connectivity mapping

International audienceAim To create an irreversible pulpitis gene signature from microarray data of healthy and inflamed dental pulps, followed by a bioinformatics approach using connectivity mapping to identify therapeutic compounds that could potentially treat pulpitis. Methodology The Gene Expression Omnibus (GEO) database, an international public repositor

Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis

Rationale: Non–cystic fibrosis bronchiectasis is characterized by airway mucus accumulation and sputum production, but the role of mucus concentration in the pathogenesis of these abnormalities has not been characterized. Objectives: This study was designed to: 1) measure mucus concentration and biophysical properties of bronchiectasis mucus; 2) identify the secreted mucins contained in bronchiectasis mucus; 3) relate mucus properties to airway epithelial mucin RNA/protein expression; and 4) explore relationships between mucus hyperconcentration and disease severity. Methods: Sputum samples were collected from subjects with bronchiectasis, with and without chronic erythromycin administration, and healthy control subjects. Sputum percent solid concentrations, total and individual mucin concentrations, osmotic pressures, rheological properties, and inflammatory mediators were measured. Intracellular mucins were measured in endobronchial biopsies by immunohistochemistry and gene expression. MUC5B (mucin 5B) polymorphisms were identified by quantitative PCR. In a replication bronchiectasis cohort, spontaneously expectorated and hypertonic saline-induced sputa were collected, and mucus/mucin concentrations were measured. Measurements and Main Results: Bronchiectasis sputum exhibited increased percent solids, total and individual (MUC5B and MUC5AC) mucin concentrations, osmotic pressure, and elastic and viscous moduli compared with healthy sputum. Within subjects with bronchiectasis, sputum percent solids correlated inversely with FEV1 and positively with bronchiectasis extent, as measured by high-resolution computed tomography, and inflammatory mediators. No difference was detected in MUC5B rs35705950 SNP allele frequency between bronchiectasis and healthy individuals. Hypertonic saline inhalation acutely reduced non–cystic fibrosis bronchiectasis mucus concentration by 5%. Conclusions: Hyperconcentrated airway mucus is characteristic of subjects with bronchiectasis, likely contributes to disease pathophysiology, and may be a target for pharmacotherapy

The x-ray polarimetry view of the accreting pulsar Cen X-3

Galaxie