1,509 research outputs found
The design and evaluation of a vibrotactile progress bar
We present an investigation into the use of Tactons to present progress information. Progress bars are common but must compete for screen space and visual attention with other visual tasks. We created a tactile progress indicator, encoding progress into a series of vibrotactile pulses. An experiment comparing the tactile progress indicator to a standard visual one showed a significant improvement in performance and an overall preference for the tactile display
Flavour Democracy in Strong Unification
We show that the fermion mass spectrum may naturally be understood in terms
of flavour democratic fixed points in supersymmetric theories which have a
large domain of attraction in the presence of "strong unification". Our
approach provides an alternative to the approximate Yukawa texture zeroes of
the Froggatt-Nielsen mechanism. We discuss a particular model based on a broken
gauged family symmetry which illustrates our approach.Comment: 21 Pages plain latex; includes 5 eps figure
The Feasibility of Adopting an Evidence-Informed Tailored Exercise Program within Adult Day Services: The Enhance Mobility Program.
This article uses the RE-AIM framework to evaluate the feasibility of implementing Enhance Mobility (EM), a tailored, evidence-informed group exercise and walking program for older adults with dementia, into an adult day services center. Participant physical performance outcomes were measured at baseline and 8 months. Program staff were interviewed to understand implementation challenges. Participant outcomes did not change significantly, though gait speed improved from limited to community ambulation levels. Implementation challenges included space reallocation and adequate staffing. Adopting EM in adult day services is feasible, and has potential to reach older adults who could benefit from tailored exercise.Ye
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Agricultural development prospects in Belize (NRI Bulletin 48)
This report is one ofthree documents completing the land resource assessment of Belize undertaken by the Natural Resources Institute (NRI)from 1986-90. The other documents are: (i) a revised national soil classification (Baillie et al., 1993) (ii) an update on 'Land in British Honduras' (Wright et al., 1959), which will present inter alia much of the NRI land resource assessment findings in a more easily readable format (Wright et al., 1993). The aim of this report is to assess the entire··agricultural resources of the country, present an assessment of how they can be used to best effect, both in the short(economically) and long terms (by protecting the environment), and present a 1:500 000 scale map indicating the preferred use for each part of the country (Map 1 ). Map 1 does not take into account current ownership, except in the case of Programme for Belize, where it is assumed that organization will continue to manage the Rio Bravo Conservation Management Area. This report also includes advice on how a Geographical Information System (GIS) can be used to update the NRI surveys and provide additional data so that the suitability of new crops and the effect of changed economic circumstances can be determined from the land resource assessment database
Cryptococcus neoformans escape From Dictyostelium amoeba by both WASH-mediated constitutive exocytosis and vomocytosis
Cryptococcus neoformans is an environmental yeast that can cause opportunistic infections in humans. As infecting animals does not form part of its normal life-cycle, it has been proposed that the virulence traits that allow cryptococci to resist immune cells were selected through interactions with environmental phagocytes such as amoebae. Here, we investigate the interactions between C. neoformans and the social amoeba Dictyostelium discoideum. We show that like macrophages, D. discoideum is unable to kill C. neoformans upon phagocytosis. Despite this, we find that the yeast pass through the amoebae with an apparently normal phagocytic transit and are released alive by constitutive exocytosis after ~80 min. This is the canonical pathway in amoebae, used to dispose of indigestible material after nutrient extraction. Surprisingly however, we show that upon either genetic or pharmacological blockage of constitutive exocytosis, C. neoformans still escape from D. discoideum by a secondary mechanism. We demonstrate that constitutive exocytosis-independent egress is stochastic and actin-independent. This strongly resembles the non-lytic release of cryptococci by vomocytosis from macrophages, which do not perform constitutive exocytosis and normally retain phagocytosed material. Our data indicate that vomocytosis is functionally redundant for escape from amoebae, which thus may not be the primary driver for its evolutionary selection. Nonetheless, we show that vomocytosis of C. neoformans is mechanistically conserved in hosts ranging from amoebae to man, providing new avenues to understand this poorly-understood but important virulence mechanism
Non-vanishing Magnetic Flux through the Slightly-charged Kerr Black Hole
In association with the Blanford-Znajek mechanism for rotational energy
extraction from Kerr black holes, it is of some interest to explore how much of
magnetic flux can actually penetrate the horizon at least in idealized
situations. For completely uncharged Kerr hole case, it has been known for some
time that the magnetic flux gets entirely expelled when the hole is
maximally-rotating. In the mean time, it is known that when the rotating hole
is immersed in an originally uniform magnetic field surrounded by an ionized
interstellar medium (plasma), which is a more realistic situation, the hole
accretes certain amount of electric charge. In the present work, it is
demonstrated that as a result of this accretion charge small enough not to
disturb the geometry, the magnetic flux through this slightly charged Kerr hole
depends not only on the hole's angular momentum but on the hole's charge as
well such that it never vanishes for any value of the hole's angular momentum.Comment: 33pages, 1 figure, Revtex, some comments added, typos correcte
Mental health of veterinary nurses and student veterinary nurses: A scoping review
Background: Research has found veterinarians around the world to be at high risk of mental health problems, but far less research has examined veterinary nurses (VNs) and student veterinary nurses (SVNs). This scoping review aimed to map existing evidence on this topic, and identify knowledge gaps.
Methods: Literature searches of MEDLINE, PsycINFO, PubMed, Web of Science, and Google Scholar were conducted, and a structured screening and selection procedure applied. To be included, studies had to be peer-reviewed, report relevant results specific to VNs and/or SVNs, and provide descriptive statistics if using quantitative methods.
Results: Of 2,118 publications identified, only 13 journal articles met the inclusion criteria. The findings were summarised in five categories: mental health and wellbeing; burnout; stress; compassion fatigue; and moral distress. While the findings of five of the studies suggested that some VNs and SVNs experienced some form of poor mental health, these lacked generalisability or transferability for multiple reasons. There was also inconsistency and ambiguity in the interpretation of findings, and incompatible or oversimplified definitions of mental health problems.
Conclusions: More research is needed to address the gaps in existing evidence supporting our understanding of VN and SVN mental health. This should establish baseline measures, and include comparisons with other occupational and national populations
PRM169 The Selection of Appropriate Health State Utility Values (Hsuvs) for Health Technology Assessment (Hta): Lessons To Be Learnt
First-principles study of stability and vibrational properties of tetragonal PbTiO_3
A first-principles study of the vibrational modes of PbTiO_3 in the
ferroelectric tetragonal phase has been performed at all the main symmetry
points of the Brillouin zone (BZ). The calculations use the local-density
approximation and ultrasoft pseudopotentials with a plane-wave basis, and
reproduce well the available experimental information on the modes at the Gamma
point, including the LO-TO splittings. The work was motivated in part by a
previously reported transition to an orthorhombic phase at low temperatures
[(J. Kobayashi, Y. Uesu, and Y. Sakemi, Phys. Rev. B {\bf 28}, 3866 (1983)]. We
show that a linear coupling of orthorhombic strain to one of the modes at Gamma
plays a role in the discussion of the possibility of this phase transition.
However, no mechanical instabilities (soft modes) are found, either at Gamma or
at any of the other high-symmetry points of the BZ.Comment: 8 pages, two-column style with 3 postscript figures embedded. Uses
REVTEX and epsf macros. Also available at
http://www.physics.rutgers.edu/~dhv/preprints/index.html#ag_pbt
Stringent bounds to spatial variations of the electron-to-proton mass ratio in the Milky Way
The ammonia method to probe variations of the electron-to-proton mass ratio,
Delta_mu/mu, is applied for the first time to dense prestellar molecular clouds
in the Milky Way. Carefully selected sample of 21 NH_3/CCS pairs observed in
the Perseus molecular cloud provide the offset Delta V (CCS-NH_3)=
36+/-7_{stat}+/-13.5_{sys} m/s . A similar offset of Delta V = 40.8 +/-
12.9_{stat} m/s between NH_3 (J,K) = (1,1) and N_2H+ J = 1-0 has been found in
an isolated dense core L183 by Pagani et al. (2009). Overall these observations
provide a safe bound of a maximum offset between ammonia and the other
molecules at the level of Delta V < 100 m/s. This bound corresponds to
Delta_mu/mu < 1E-7, which is an order of magnitude more sensitive than
available extragalactic constraints. Taken at face value the measured Delta V
shows positive shifts between the line centers of NH_3 and these two other
molecules and suggest a real offset, which would imply a Delta_mu/mu about
4E-8. If Delta_mu/mu follows the gradient of the local gravitational potential,
then the obtained results are in conflict with laboratory atomic clock
experiments in the solar system by 5 orders of magnitude, thus requiring a
chameleon-type scalar field model. New measurements involving other molecules
and a wider range of objects along with verification of molecular rest
frequencies are currently planned to confirm these first indications.Comment: 7 pages +2 figures. Galileo Galilei Institute Conferences on Dark
Matter and Dark Energ
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