Carcass Compound Materials Base on Fluoropolymer for Tissue Engineering in Orthopedics

In this work new type of composite materials for application as coatings for intramedullary implants in the field of orthopaedics and traumatology is offered. Method is based on ability of fluoropolymers to act as biologically inert binding agent and ability of fine-dyspersated hydroxyapatite powders to act as biologically active filling agent providing osteoinduction and osteoconduction processes. Results of investigations of adhesion, elastic and morphometric characteristics of offered composite were presented; chemical composition was determined. Estimation of toxicological properties, locally irritant action and hemolytic activity of offered composites was done according to GOST R ISO 10993. In vivo tests were carried out; it was shown that offered composites didn’t cause any negative tissue reactions and stimulated osteogenesis processes in ectopic bone formation test. Key words: Carcass Compound Materials; fluoropolymers; orthopaedi

Fabrication and properties of L-arginine-doped PCL electrospun composite scaffolds

The article describes fabrication and properties of composite fibrous scaffolds obtained by electrospinning of the solution of poly({\epsilon}-caprolactone) and arginine in common solvent. The influence of arginine content on structure, mechanical, surface and biological properties of the scaffolds was investigated. It was found that with an increase of arginine concentration diameter of the scaffold fibers was reduced, which was accompanied by an increase of scaffold strength and Young modulus. It was demonstrated that porosity and water contact angle of the scaffold are independent from arginine content. The best cell adhesion and viability was shown on scaffolds with arginine concentration from 0.5 to 1 % wt

Modification of the zirconia ceramics by different calcium phosphate coatings:comparative study

The aim of this study was to characterize different calcium phosphate coatings and evaluate in vitro cell response of these materials to ceramics implants. The physical and chemical properties of calcium phosphate coatings formed by RF-magnetron sputtering of calcium phosphate tribasic, hydroxyapatite, calcium phosphate monobasic, calcium phosphate dibasic dihydrate and calcium pyrophosphate powders were characterized. Cell adhesion and cell viability were examined on calcium phosphate coatings using mesenchymal stem cells. The results of cytotoxicity measurements of the calcium phosphate coatings revealed that only the coating obtained by RF-magnetron sputtering of the calcium phosphate dibasic dihydrate and calcium phosphate tribasic powders possessed lower cell viability than the zirconia substrate. The coating formed by sputtering of the calcium phosphate tribasic powder demonstrated more cells adhered onto its surface compared with other calcium phosphate coatings

Energetics of Propellant Options for High-Power Hall Thrusters

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76265/1/AIAA-16376-173.pd

Influence of magnesium and strontium substitutions in the structure of hydroxyapatite lattice on the deposition rate and properties of the CaP coatings formed via RF-sputtering of the powder targets

This work is dedicated to studying of the properties of the calcium phosphate (CaP) coatings deposited on Ti substrates by radio-frequency magnetron sputtering (RFMS) of three hydroxyapatite-based powder targets: pure hydroxyapatite (HA), Mg-substituted HA (Mg-HA, Mg = 0.93 ± 0.13 at.%) and Sr-substituted HA (Sr-HA, Sr ∼ 0.47 at.%). The influence of ionic substitutions in the structure of the sputtered targets on the surface morphology, physicochemical properties of the coatings and their wettability were studied. It is revealed that Mg and Sr ionic substitutions in the crystal lattice of HA at these concentrations don't affect deposition rate, however, it influences morphology, wettability and elemental and phase composition of deposited coatings

Influence of the high-power ion-beam irradiation of a hydroxyapatite target on the properties of formed calcium phosphate coatings

The physical-mechanical of properties of biocompatible calcium phosphate coatings deposited onto titanium and silicon substrates from erosion materials, which are generated by irradiating hydroxyapatite (synthetic and natural) targets by means of the high-power pulsed ion beam of a Temp-4 accelerator, are investigated. A calculation technique for predicting the rate and energy efficiency of deposition using pulsed ion beams is proposed. Their characteristics are analyzed as applied to the formation of calcium phosphate coatings

Modification of the zirconia ceramics by different calcium phosphate coatings:comparative study

The aim of this study was to characterize different calcium phosphate coatings and evaluate in vitro cell response of these materials to ceramics implants. The physical and chemical properties of calcium phosphate coatings formed by RF-magnetron sputtering of calcium phosphate tribasic, hydroxyapatite, calcium phosphate monobasic, calcium phosphate dibasic dihydrate and calcium pyrophosphate powders were characterized. Cell adhesion and cell viability were examined on calcium phosphate coatings using mesenchymal stem cells. The results of cytotoxicity measurements of the calcium phosphate coatings revealed that only the coating obtained by RF-magnetron sputtering of the calcium phosphate dibasic dihydrate and calcium phosphate tribasic powders possessed lower cell viability than the zirconia substrate. The coating formed by sputtering of the calcium phosphate tribasic powder demonstrated more cells adhered onto its surface compared with other calcium phosphate coatings

Experimental Evaluation of Russian Anode Layer Thrusters

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76973/1/AIAA-1994-3010-800.pd