4,171 research outputs found
Measurement of the lepton charge asymmetry in inclusive W production in pp collisions at √s = 7TeV at the CMS experiment
Lepton charge asymmetry in inclusive pp → WX production at
s = 7TeV has been measured by the CMS detector at the LHC, using 36 pb−1 of data. These measurements, performed in both W → eν and W → μν channels, provide new insights into proton structure functions
Prediction in forensic science: a critical examination of common understandings
In this commentary, we argue that the term 'prediction' is overly used when in fact, referring to foundational writings of de Finetti, the correspondent term should be inference. In particular, we intend (i) to summarize and clarify relevant subject matter on prediction from established statistical theory, and (ii) point out the logic of this understanding with respect practical uses of the term prediction. Written from an interdisciplinary perspective, associating statistics and forensic science as an example, this discussion also connects to related fields such as medical diagnosis and other areas of application where reasoning based on scientific results is practiced in societal relevant contexts. This includes forensic psychology that uses prediction as part of its vocabulary when dealing with matters that arise in the course of legal proceedings
La naturaleza decisoria de las conclusiones de los expertos en ciencia forense (The decisionalization of individualization)
En la ciencia forense y ramas de la ciencia adyacentes, tanto investigadores del ámbito académico como quienes las practican continúan divergiendo en la percepción y comprensión del término “individualización”, es decir, la defensa de la tesis de que es posible reducir un conjunto de potenciales donantes de un vestigio forense a una única fuente. En concreto, se ha puesto de manifiesto que recientes cambios que entienden la práctica de la individualización como una decisión no son más que un mero cambio de etiqueta [1], dejando los cambios fundamentales en el orden del pensar y del entender aún pendientes. Es más, asociaciones profesionales y expertos huyen de adherirse a la noción de decisión tal y como la define la teoría formal de la decisión en la que la individualización puede contextualizarse, principalmente por las dificultades para tratar sobre las medidas de deseabilidad o no de las consecuencias de las decisiones (por ejemplo, utilizando las funciones de utilidad). Apoyándose en investigaciones existentes en esta área, este artículo presenta y discute sobre conceptos fundamentales de utilidades y costes, con particular referencia a su aplicación a la individualización forense. El artículo subraya que una adecuada comprensión de las herramientas de la decisión no solo reduce el número de asignaciones individuales que la aplicación de la teoría de la decisión requiere, sino que también muestra cómo esas asignaciones pueden relacionarse significativamente con las propiedades constituyentes del problema de la decisión en el mundo real al que se aplica la teoría. Se argumenta que la “decisionalización” de la individualización requiere esa percepción fundamental para iniciar cambios en las comprensiones subyacentes de esos campos, no meramente en el ámbito de sus etiquetas
Bayes Factors for Forensic Decision Analyses with R
Bayes Factors for Forensic Decision Analyses with R provides a self-contained introduction to computational Bayesian statistics using R. With its primary focus on Bayes factors supported by data sets, this book features an operational perspective, practical relevance, and applicability—keeping theoretical and philosophical justifications limited. It offers a balanced approach to three naturally interrelated topics:
– Probabilistic Inference: Relies on the core concept of Bayesian inferential statistics, to help practicing forensic scientists in the logical and balanced evaluation of the weight of evidence.
– Decision Making: Features how Bayes factors are interpreted in practical applications to help address questions of decision analysis involving the use of forensic science in the law.
– Operational Relevance: Combines inference and decision, backed up with practical examples and complete sample code in R, including sensitivity analyses and discussion on how to interpret results in context.
Over the past decades, probabilistic methods have established a firm position as a reference approach for the management of uncertainty in virtually all areas of science, including forensic science, with Bayes' theorem providing the fundamental logical tenet for assessing how new information—scientific evidence—ought to be weighed. Central to this approach is the Bayes factor, which clarifies the evidential meaning of new information, by providing a measure of the change in the odds in favor of a proposition of interest, when going from the prior to the posterior distribution. Bayes factors should guide the scientist's thinking about the value of scientific evidence and form the basis of logical and balanced reporting practices, thus representing essential foundations for rational decision making under uncertainty.
This book would be relevant to students, practitioners, and applied statisticians interested in inference and decision analyses in the critical field of forensic science. It could be used to support practical courses on Bayesian statistics and decision theory at both undergraduate and graduate levels, and will be of equal interest to forensic scientists and practitioners of Bayesian statistics for driving their evaluations and the use of R for their purposes
Magnon softening in a ferromagnetic monolayer: a first-principles spin dynamics study
We study the Fe/W(110) monolayer system through a combination of first
principles calculations and atomistic spin dynamics simulations. We focus on
the dispersion of the spin waves parallel to the [001] direction. Our results
compare favorably with the experimental data of Prokop et al. [Phys. Rev. Lett.
102, 177206], and correctly capture a drastic softening of the magnon spectrum,
with respect to bulk bcc Fe. The suggested shortcoming of the itinerant
electron model, in particular that given by density functional theory, is
refuted. We also demonstrate that finite temperature effects are significant,
and that atomistic spin dynamics simulations represent a powerful tool with
which to include these.Comment: v1: 11 pages, 3 figures. v2: double column, 5 pages, 3 figures, typos
corrected, references adde
Health Care Financing Reforms in Italy: Projects of Jefferson\u27s Center for Research in Medical Education and Health Care
No abstract available
Reconsiderando la individualización forense como una decisión = Rethinking forensic individualization as a decision
Thiahelicene-grafted halloysite nanotubes: Characterization, biological studies and pH triggered release
Thiahelicene-grafted halloysite nanotubes: Characterization, biological studies and pH triggered release
A novel drug delivery nanosystem was here designed, linking thiahelicenes to halloysite nanotubes. Tetrathia[7]helicenes are very promising DNA intercalators, whose usage in biomedical field has been so far limited by their poor bioavailability. The study of appropriate drug delivery systems is needed to exploit helicenes as therapeutics. In this work, imine chemistry was adopted to covalently attach the bioactive compound and release it in acidic environments such as those surrounding tumour cells. To this aim, halloysite nanotubes were functionalized with (3-aminopropyl)triethoxysilane. The latter acted as linker providing NH2 groups to react with the formyl moiety of the thiahelicene derivative. The nanoconstruct preparation was studied in depth by surface-sensitive spectroscopies and angle-resolved X-ray absorption, to investigate the attachment mode, surface coverage and molecular orientation of the thiahelicene units. Release tests were carried out also in vitro on two tumour cell lines with different extracellular pH values. Mildly acidic pH conditions catalyzed the hydrolysis of the imine bond and promoted the cytotoxic compound release, which proved selective to slight pH differences, confirming the potential of this novel nanoconstruct
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