Spin dynamics in the antiferromagnetic phase for electron-doped cuprate superconductors

Based on the $t$-$t'$-$t''$-$J$ model we have calculated the dynamical spin susceptibilities in the antiferromagnetic (AF) phase for electron-doped cuprates, by use of the slave-boson mean-field theory and random phase approximation. Various results for the susceptibilities versus energy and momentum have been shown at different dopings. At low energy, except the collective spin-wave mode around $(\pi,\pi)$ and 0, we have primarily observed that new resonance peaks will appear around $(0.3\pi,0.7\pi)$ and equivalent points with increasing doping, which are due to the particle-hole excitations between the two AF bands. The peaks are pronounced in the transverse susceptibility but not in the longitudinal one. These features are predicted for neutron scattering measurements.Comment: 5 pages, 3 figures, published version with minor change

In vitro bioaccessibility of calcium, iron and zinc from breads and bread spreads

The in vitro bioaccessibility of calcium, iron and zinc of breads added with different bread spreads was determined. The mineral contents were assessed by flame atomic absorption spectrophotometer and expressed in fresh weight (mg/100 g). For the mineral bioaccessibility determination, in vitro gastrointestinal digestion was applied. Among the bread samples, calcium content of wholemeal bread with chocolate hazelnut spread ranked the highest (159.96±0.869 mg/100 g). For iron, white bread with chocolate hazelnut spread (6.92±0.411 mg/100 g) showed highest iron content while for zinc, white bread with peanut butter was the highest (1.82±0.015 mg/100 g). For calcium bioaccessibility, white bread with orange marmalade ranked the highest (39.33±4.865%) while wholemeal bread with peanut butter (14.70±0.265%) showed the lowest. The application of orange marmalade spread onto wholemeal bread increased the iron bioaccessibility significantly (9.73±1.387%). The acidic properties attributed by organic acids found in orange marmalade may favour both calcium and iron absorption. The zinc bioaccessibility of white bread alone remained the highest (20.63±3.536%) while wholemeal bread added with peanut butter (5.90±1.137%) showed the lowest. Overall, the addition of bread spreads particularly peanut butter and chocolate hazelnut spread had increased mineral contents of the bread samples. However, the presence of mineral enhancers (organic acids) and inhibitors (phytate and polyphenols) played some significant role in influencing the mineral bioaccessibility

Fabrication of a focusing soft X-ray collector payload

A large area X-ray focusing collector with arc minute resolution and a position sensitive detector capable of operating in the soft X-ray region was developed for use on sounding rockets in studying stellar X-ray sources. The focusing payload consists of the following components, which are described: (1) a crossed paraboloid mirror assembly; (2) an aspect camera and star tracker; (3) a focal plane assembly containing an imaging proportional counter and its preamplifiers, high voltage power supplies and gas system; (4) a fiducial system; and (5) housekeeping, data handling, instrumentation and telemetry electronics. The design, tests, and operation are described

In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.

BackgroundCruzain, the major cysteine protease of Trypanosoma cruzi, is an essential enzyme for the parasite life cycle and has been validated as a viable target to treat Chagas' disease. As a proof-of-concept, K11777, a potent inhibitor of cruzain, was found to effectively eliminate T. cruzi infection and is currently a clinical candidate for treatment of Chagas' disease.Methodology/principal findingsWRR-483, an analog of K11777, was synthesized and evaluated as an inhibitor of cruzain and against T. cruzi proliferation in cell culture. This compound demonstrates good potency against cruzain with sensitivity to pH conditions and high efficacy in the cell culture assay. Furthermore, WRR-483 also eradicates parasite infection in a mouse model of acute Chagas' disease. To determine the atomic-level details of the inhibitor interacting with cruzain, a 1.5 A crystal structure of the protease in complex with WRR-483 was solved. The structure illustrates that WRR-483 binds covalently to the active site cysteine of the protease in a similar manner as other vinyl sulfone-based inhibitors. Details of the critical interactions within the specificity binding pocket are also reported.ConclusionsWe demonstrate that WRR-483 is an effective cysteine protease inhibitor with trypanocidal activity in cell culture and animal model with comparable efficacy to K11777. Crystallographic evidence confirms that the mode of action is by targeting the active site of cruzain. Taken together, these results suggest that WRR-483 has potential to be developed as a treatment for Chagas' disease

Radiation-induced magnetoresistance oscillations in two-dimensional electron systems under bichromatic irradiation

We analyze the magnetoresistance $R_{xx}$ oscillations in high-mobility two-dimensional electron systems induced by the combined driving of two radiation fields of frequency $\omega_1$ and $\omega_2$, based on the balance-equation approach to magnetotransport for high-carrier-density systems in Faraday geometry. It is shown that under bichromatic irradiation of $\omega_2\sim 1.5 \omega_1$, most of the characterstic peak-valley pairs in the curve of $R_{xx}$ versus magnetic field in the case of monochromatic irradiation of either $\omega_1$ or $\omega_2$ disappear, except the one around $\omega_1/\omega_c\sim 2$ or $\omega_2/\omega_c\sim 3$. $R_{xx}$ oscillations show up mainly as new peak-valley structures around other positions related to multiple photon processes of mixing frequencies $\omega_1+\omega_2$, $\omega_2-\omega_1$, etc. Many minima of these resistance peak-valley pairs can descend down to negative with enhancing radiation strength, indicating the possible bichromaticzero-resistance states.Comment: 5 pages, 3 figures. Accepted for publication in Phys. Rev.

Impurity-induced Local Density of States in a D-wave Superconductor Carrying a Supercurrent

The local density of states (LDOS) and its Fourier component induced by a unitary impurity in a supercurrent-carrying d-wave superconductor are investigated. Both of these quantities possess a reflection symmetry about the line passing through the impurity site and along the supercurrent if it is applied along the antinodal or nodal direction. With increasing supercurrent, both the coherence and resonant peaks in the LDOS are suppressed and slightly broadened. Under a supercurrent along the antinodal direction, the coherence peaks split into double peaks. The modulation wavevectors associated with elastic scatterings of quasiparticles by the defect from one constant-energy piece of the Fermi surface to another are displayed as bright or dark spots in the Fourier space of the LDOS image, and they may be suppressed or enhanced, and shifted depending on the applied current and the bias voltage.Comment: 5 pages, 6 figure

Topological Phases in Neuberger-Dirac operator

The response of the Neuberger-Dirac fermion operator D=\Id + V in the topologically nontrivial background gauge field depends on the negative mass parameter $m_0$ in the Wilson-Dirac fermion operator $D_w$ which enters $D$ through the unitary operator $V = D_w (D_w^{\dagger} D_w)^{-1/2}$. We classify the topological phases of $D$ by comparing its index to the topological charge of the smooth background gauge field. An exact discrete symmetry in the topological phase diagram is proved for any gauge configurations. A formula for the index of D in each topological phase is derived by obtaining the total chiral charge of the zero modes in the exact solution of the free fermion propagator.Comment: 27 pages, Latex, 3 figures, appendix A has been revise

A survey of cost-sensitive decision tree induction algorithms

The past decade has seen a significant interest on the problem of inducing decision trees that take account of costs of misclassification and costs of acquiring the features used for decision making. This survey identifies over 50 algorithms including approaches that are direct adaptations of accuracy based methods, use genetic algorithms, use anytime methods and utilize boosting and bagging. The survey brings together these different studies and novel approaches to cost-sensitive decision tree learning, provides a useful taxonomy, a historical timeline of how the field has developed and should provide a useful reference point for future research in this field

Structural investigation of MOVPE-Grown GaAs on Ge by X-ray techniques

The selection of appropriate characterisation methodologies is vital for analysing and comprehending the sources of defects and their influence on the properties of heteroepitaxially grown III-V layers. In this work we investigate the structural properties of GaAs layers grown by Metal-Organic Vapour Phase Epitaxy (MOVPE) on Ge substrates – (100) with 6⁰ offset towards – under various growth conditions. Synchrotron X-ray topography (SXRT) is employed to investigate the nature of extended linear defects formed in GaAs epilayers. Other X-ray techniques, such as reciprocal space mapping (RSM) and triple axis ω-scans of (00l)-reflections (l = 2, 4, 6) are used to quantify the degree of relaxation and presence of antiphase domains (APDs) in the GaAs crystals. The surface roughness is found to be closely related to the size of APDs formed at the GaAs/Ge heterointerface, as confirmed by X-ray diffraction (XRD), as well as atomic force microscopy (AFM), and transmission electron microscopy (TEM)

Structural investigation of MOVPE-Grown GaAs on Ge by X-ray techniques

The selection of appropriate characterisation methodologies is vital for analysing and comprehending the sources of defects and their influence on the properties of heteroepitaxially grown III-V layers. In this work we investigate the structural properties of GaAs layers grown by Metal-Organic Vapour Phase Epitaxy (MOVPE) on Ge substrates – (100) with 6⁰ offset towards – under various growth conditions. Synchrotron X-ray topography (SXRT) is employed to investigate the nature of extended linear defects formed in GaAs epilayers. Other X-ray techniques, such as reciprocal space mapping (RSM) and triple axis ω-scans of (00l)-reflections (l = 2, 4, 6) are used to quantify the degree of relaxation and presence of antiphase domains (APDs) in the GaAs crystals. The surface roughness is found to be closely related to the size of APDs formed at the GaAs/Ge heterointerface, as confirmed by X-ray diffraction (XRD), as well as atomic force microscopy (AFM), and transmission electron microscopy (TEM)