Significance of Non-urological Clinical Indices in Management of Prostate Cancer

Background: To have a re-look at the common non-urological features of prostate cancer with a view of determining if the non-urological presenting symptoms in patients with carcinoma of the prostate are of any significance or use as applicable indices in their management, especially in developing countries. Method: Twenty-seven patients with carcinoma of the prostate and twenty patients with benign prostatic enlargement presenting over a five-year period were studied. From the data on both groups of patients, the sensitivities, specificities, predictive values, and usefulness indices of the non-urological symptoms of carcinoma of the prostate were determined. Result: The commonest non-urological symptoms of carcinoma of the prostate were constipation, pedal oedema, weight loss, waist pain, abdominal pain/discomfort, generalized body weakness, and inability to walk. All the symptoms were of relatively poor sensitivity and negative predictive value, but specificity and positive predictive value were relatively high, and were remarkably so for pedal oedema, weight loss, generalized body weakness, inability to walk, and chest pain. None of the symptoms was found to be useful in the management of the patient as none attained the minimum acceptable usefulness index. Conclusion: Non-urological symptoms of carcinoma of the prostate are not useful indices for the detection and management of CAP. Efforts should be made to ensure provision of the minimal facilities for the management of carcinoma of the prostate in healthcare facilities in the developing countries.Fond : Pour une revue plus profonde des dispositifs non urologiques communs du cancer de prostate avec une vue de d\ue9terminer si les sympt\uf4mes de pr\ue9sentation non urologiques dans les malades pr\ue9sentant le carcinome de la prostate sont de n'importe quelle importance ou employ\ue9s en tant qu'index applicables dans leur traitement, particuli\ue8rement dans les pays en voie de d\ue9veloppement. M\ue9thode : Vingt-sept malades de pr\ue9sentant le carcinome de la prostate et vingt malades pr\ue9sentant l'agrandissement prostatique b\ue9nin sur une p\ue9riode de cinq ans ont \ue9t\ue9 \ue9tudi\ue9s. \uc0 partir des donn\ue9es sur les deux groupes de patients, les sensibilit\ue9s, les sp\ue9cificit\ue9s, les valeurs pr\ue9dictives, et les index d'utilit\ue9 des sympt\uf4mes non urologiques du carcinome de la prostate ont \ue9t\ue9 d\ue9termin\ue9s. R\ue9sultat : Les sympt\uf4mes non urologiques les plus communs du carcinome de la prostate \ue9taient constipation, oed\ue8me de p\ue9dale, perte de poids, douleur de taille, douleur abdominaux, faiblesse g\ue9n\ue9ralis\ue9e de corps, et incapacit\ue9 de marcher. Tous les sympt\uf4mes \ue9taient de sensibilit\ue9 relativement faible et valeur pr\ue9dictive n\ue9gative, mais la sp\ue9cificit\ue9 et la valeur pr\ue9dictive positive \ue9taient relativement hautes, et \ue9taient remarquablement ainsi pour l'oed\ue8me de p\ue9dale, perte de poids, la faiblesse de corps g\ue9n\ue9ralis\ue9e, l'incapacit\ue9 de marcher, et la douleur de coffre. Aucun des sympt\uf4mes n'est consid\ue8re utile dans le traitement du malade endant qu'aucun n'atteignait l'index acceptable minimum d'utilit\ue9. Conclusion : les sympt\uf4mes Non urologiques du carcinome de la prostate ne sont pas des index utiles pour la d\ue9tection et le traitement du CAP. Des efforts devraient \uea tre faits pour garantir la disposition de l'\ue9quipement minimal du traitement de carcinome de la prostate dans le centre de soins m\ue9dicaux dans les pays en voie de d\ue9veloppement

Post-Partum Infarction Of An Axillary Breast Case Report

No Abstract Nigerian Journal of Clinical Practice Vol. 10 (4) 2007 pp. 355-35