645 research outputs found

    Free amino acids of the blood and some organs in hypokinesia

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    The metabolic fund of amino acids of the blood and tissues of rats under hypokinesia was investigated. The content of free amino acids was determined for the liver, kidney, brain, and the skeletal and cardiac muscles after established periods of hypokinesia. It was found that the total content of free amino acids in the experimental animals was, on the average 19 percent lower than in the controls. The results of the quantity of individual compounds indicate that the level of some were reduced while others were increased. It was also found that there was an unequal content of individual amino acids in the different tissues

    Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing

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    Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells. Co-colonization by Sp and a Gram-negative species, Haemophilus influenzae (Hi), provides sufficient stimulus to induce neutrophil and complement-mediated clearance of Sp from the mucosal surface in a murine model. Products from Hi, but not Sp, also promote killing of Sp by ex vivo neutrophil-enriched peritoneal exudate cells. Here we identify the stimulus from Hi as its peptidoglycan. Enhancement of opsonophagocytic killing was facilitated by signaling through nucleotide-binding oligomerization domain-1 (Nod1), which is involved in recognition of γ-D-glutamyl-meso-diaminopimelic acid (meso-DAP) contained in cell walls of Hi but not Sp. Neutrophils from mice treated with Hi or compounds containing meso-DAP, including synthetic peptidoglycan fragments, showed increased Sp killing in a Nod1-dependent manner. Moreover, Nod1-/- mice showed reduced Hi-induced clearance of Sp during co-colonization. These observations offer insight into mechanisms of microbial competition and demonstrate the importance of Nod1 in neutrophil-mediated clearance of bacteria in vivo

    Video Wall Control System Development

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    The purpose of this work is to develop a video wall management system. In this work, a technical task was drawn up for the development of its own system with thejustification of the chosen method of implementation. Then, for a more actual version, the application architecture was compiled, and development tools were selected. Based on the set of acquired knowledge about the field of activity, a video wall management system was developed. This system uses web technologies to communicate with the user and display the final content on the video wall. Usability and efficiency of the system were confirmed as a result of successful testing on several virtual devices in the local network. Using the system reduces the time spent on setting up and managing the content of the video wall. © 2022 American Institute of Physics Inc.. All rights reserved.Simos T.E.Simos T.E.Simos T.E.Simos T.E.Tsitouras C

    Effect of ion-plasma treatment on oxidation-reduction processes in lithium-titanium-zinc ferrites

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    We examined the effect of nitrogen, oxygen and argon plasma on the diffusion-controlled oxidation-reduction processes in lithium-titanium-zinc ferrite ceramics by measuring the activation energy of electrical conductivity in the depth of the sample. The experimental results show that the high-temperature treatment in polycrystalline ferrites by nitrogen or argon ion plasma greatly accelerates the oxidation-reduction processes in ferrites and changes the process direction depending on the partial pressure of oxygen

    Scythian complexes of barrows 5 and 6 from the "Garden" group on the left bank of the Lower Dniester = Скифские комплексы курганов 5 и 6 группы "Сад" на левобережье Нижнего Днестра

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    The authors analyze the evidence obtained during the excavation of barrows 5 and 6 from the “Garden” group near the Glinoe village in the Slobodzeia district on the left bank of the Lower Dniester. These barrows demonstrate not only Thracian and Greek influence on the material culture of Scythians of the northwestern Black Sea region, but also the fact that Scythian steppe culture developed continually in the Dniester region throughout the fourth to second centuries B

    WINTER HARDINESS OF BREAD WHEAT FROM THE VIR COLLECTION IN ENVIRONMENTS OF THE NORTHWESTERN AND CENTRAL BLACK SOIL REGIONS OF RUSSIA

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    Background. Winter wheat resistance to adverse winter­ing conditions is one of the most important adaptive charac­teristics. To obtain high yields, modern wheat cultivars should have various protective reactions. For their success­ful combination in one genotype, the availability of appro­priate initial material is of great importance. In Russia, the accessions from the VIR collection are traditionally used as initial material for wheat breeding. The aims of the present study were (1) to evaluate winter hardiness in accessions from the VIR collection in a field test, and (2) to use the ob­tained data and those on the geographical origin of acces­sions for making up the target sub-collection and perform­ing its eco-geographical studies.Materials and methods. The initial sample for field screening contained 431 acces­sions of common winter wheat from different regions of Russia and the former USSR, and 484 accessions from 18 foreign countries. Winter hardiness of these accessions was tested in the environmental conditions of the North­western region (Pushkin, 59°41′N 30°20′E, 2006/2007, 2007/2008 and 2013/2014) and of the Central Black Soil re­gion (Yekaterinino, 52°59′N 40°50′E, Tambov Province, 2007/2008 and 2008/2009). The degree of winter hardi­ness was determined in accordance with the technique de­veloped at VIR.Results and conclusions. In 2006/2007, in Pushkin, a high and a very high degree of winter hardiness was displayed by 114 accessions with the origin from Rus­sia and the former USSR as well as by 12 accessions from foreign countries. Based on the obtained data and taking into account the diversity of the geographical origin of ac­cessions, the target sub-collection was formed, whose ac­cessions were subjected to eco-geographical two-year field studies (Pushkin, 59°41′N 30°20′E, 2007/2008, 2013/2014, and Yekaterinino, 52°59′N 40°50′N, Tambov Province, 2007/2008, 2008/2009). The Friedman’s variance analysis has shown that variation on winter hardiness in 158 acces­sions from the target sub-collection was determined by the environmental conditions of wheat cultivation (χ2э = 256.7; df = 4; χ2W=0.05 = 9.5) and by genetic differences between ac­cessions (χ2э = 239.3; df = 157; χ2W=0.05 = 187.2) at that effect of the prior was stronger than that of the latter. By using the cluster analysis (k-means algorithm), the target sub-collec­tion structure has been revealed. Twelve accessions that overwintered well at both geographical locations during all the years of testing were identified
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