11,071 research outputs found

    Randomised positive control trial of NSAID and antimicrobial treatment for calf fever caused by pneumonia

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    One hundred and fifty-four preweaning calves were followed between May and October 2015. Calves were fitted with continuous monitoring temperature probes (TempVerified FeverTag), programmed so a flashing light emitting diode (LED) light was triggered following six hours of a sustained ear canal temperature of ≥39.7°C. A total of 83 calves (61.9 per cent) developed undifferentiated fever, with a presumptive diagnosis of pneumonia through exclusion of other calf diseases. Once fever was detected, calves were randomly allocated to treatment groups. Calves in group 1 (NSAID) received 2 mg/kg flunixin meglumine (Allevinix, Merial) for three consecutive days and group 2 (antimicrobial) received 6 mg/kg gamithromycin (Zactran, Merial). If fever persisted for 72 hours after the initial treatment, calves were given further treatment (group 1 received antimicrobial and group 2 received NSAID). Calves in group 1 (NSAID) were five times more likely (P=0.002) to require a second treatment (the antimicrobial) after 72 hours to resolve the fever compared with the need to give group 2 (antimicrobial) calves a second treatment (NSAID). This demonstrates the importance of ongoing monitoring and follow-up of calves with respiratory disease. However, of calves with fever in group 1 (NSAID), 25.7 per cent showed resolution following NSAID-only treatment with no detrimental effect on the development of repeated fever or daily live weight gain. This suggests that NSAID alone may be a useful first-line treatment, provided adequate attention is given to ongoing monitoring to identify those cases that require additional antimicrobial treatment

    P and T Violation From Certain Dimension Eight Weinberg Operators

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    Dimension eight operators of the Weinberg type have been shown to give important contributions to CP violating phenomena, such as the electric dipole moment of the neutron. In this note we show how operators related to these (and expected to occur on equal footing) can give rise to time-reversal violating phenomena such as atomic electric dipole moments. We also estimate the induced parity violating phenomena such as small ``wrong'' parity admixtures in atomic states and find that they are negligible. Uses harvmac.tex and epsf.tex; one figure submitted as a uuencoded, compressed EPS file.Comment: 6 pages, EFI-92-5

    INTERACTION OF FLUORIDE COMPLEXES DERIVED FROM GLASS-IONOMER CEMENTS WITH HYDROXYAPATITE

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    A study has been undertaken of the interaction of complexed fluoride extracted from glass-ionomer dental cements with synthetic hydroxyapatite powder. Extracts were prepared from two commercial glass-ionomers (Fuji IX and ChemFlex) under both neutral and acidic conditions. They were analysed by ICP-OES and by fluoride-ion selective electrode with and without added TISAB to decomplex the fluoride. The pH of the acid extracts was 4, conditions under which fluoride complexes with protons as HF or HF2-, it also complexes with aluminium, which was found to be present in higher amounts in the acid extracts. Fluoride was found to be almost completely complexed in acid extracts, but not in neutral extracts, which contained free fluoride ions. Exposure of these extracts to synthetic hydroxyapatite powder showed that fluoride was taken up rapidly (within 5 minutes), whether or not it was complexed. SEM (EDAX) study of recovered hydroxyapatite showed only minute traces of aluminium taken up under all conditions. This showed that aluminium interacts hardly at all with hydroxyapatite, and hence is probably not involved in the remineralisation process

    Universal Dynamic Conductivity and Quantized Visible Opacity of Suspended Graphene

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    We show that the optical transparency of suspended graphene is defined by the fine structure constant, alpha, the parameter that describes coupling between light and relativistic electrons and is traditionally associated with quantum electrodynamics rather than condensed matter physics. Despite being only one atom thick, graphene is found to absorb a significant (pi times alpha=2.3%) fraction of incident white light, which is a consequence of graphene's unique electronic structure. This value translates into universal dynamic conductivity G =e^2/4h_bar within a few percent accuracy

    3,4-O-Isopropyl­idene-2-C-methyl-d-galactonolactone

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    X-ray crystallography unequivocally confirmed the stereochemistry of the 2-C-methyl group in the title mol­ecule, C10H16O6, in which the 1,5-lactone ring exists in a boat conformation. The use of d-galactose in the synthesis determined the absolute stereochemistry. The crystal exists as O—H⋯O hydrogen-bonded layers in the ab plane, with each mol­ecule acting as a donor and acceptor for two hydrogen bonds
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