Temporal analysis of natural radionuclides deposition at Málaga(2005-2016)

Atmospheric deposition of radionuclides has been investigated in many studies from the aspects of both radiation protection and geochemistry. The present study, carried out in the city of Málaga, in the southeast of Spain, focuses on the assessment of the bulk depositional fluxes of three natural radionuclides: 7Be (cosmogenic origin), and 210Pb and 40K (crustal origin). These three radionuclides are useful markers of particles arising from their respective sources. To obtain fundamental information of atmospheric transportation, sedimentation and geological process of particulate matter, a long-term monitoring of atmospheric deposition has been carried out in Málaga from January 2005-December 2016. Samples of bulk deposition were collected on a monthly basis on a stainless steel tray from January 2005 to December 2016. Afterwards, a volume of 6 L of the bulk deposition was reduced via evaporation to 1 L approximately and transferred to a Marinelli geometry container for gamma counting. Additionally, aerosols samples were collected weekly in cellulose membrane filters of 0.8μm pore size and 47mm diameter with an air sampler lodged in an all-weather sampling station, situated on the roof near the bulk rain collector. Gamma counting of the aerosols and bulk deposition samples was performed using an intrinsic germanium coaxial detector, Re-Ge-type (CANBERRA). This study describes the results and then discusses characteristics of atmospheric deposition of mentioned radionuclides with respect to seasonal variations and dependency on controlling factors. The depositional fluxes of all radionuclides showed a clear seasonal trend with summer minimum and high values in wintertime

Diagnóstico y medidas de remediación por altas concentraciones de radón en vivienda unifamiliar en el sur de España

Desde hace años existe una importante preocupación e interés en la comunidad científica por la exposición a altos niveles de radon en el interior de la viviendas, centros de trabajo y colegios. Esta preocupación se está extendiendo al conjunto de la población y son numerosas las referencias en artículos de prensa y medios de comunicación a este gas noble. Es bien sabido que las personas que inhalan altas concentraciones de radón tienen un riesgo mayor de padecer cáncer de pulmón, que es inducido por los descendientes del gas inhalado. En este trabajo presentamos los datos más relevantes obtenidos en una vivienda unifamiliar en la que los propietarios sospechaban de estar sometidos a altas concentraciones de radon. Para realizar el estudio utilizamos sistemas activos, concretamente 6 dispositivos con cámara de difusión con diodo de silicio, modelo Alpha E de Saphimo y un equipo AlphaGuard 2000 Pro, y sistemas pasivos mediante cartuchos de carbón activo para medidas en equipo de espectrometría gamma. Se trata de una vivienda de 550 m2 distribuidos en dos módulos con dos alturas y sótano acondicionado como vivienda del servicio. Tras una evaluación inicial en toda la vivienda, detectamos altos niveles de radon en tres estancias de la casa, registrando valores medios >6000 Bqm-3 con un valor máximo de 25350 Bqm-3. Se realizaron medidas correctoras mediante el uso de materiales impermeabilizantes y sistemas de extracción forzada en la zona no habitada del sótano consiguiendo disminuir los niveles de radon por debajo de los 100 Bqm-3 como valor medio

Decreased phosphate reabsorption by volume expansion in the dog

Decreased phosphate reabsorption by volume expansion in the dog. The effect of volume expansion on tubular phosphate reabsorption (TRP) was studied in intact and acutely thyroparathyroidectomized (TPTX) dogs infused with a neutral phosphate solution. The infusion of a Ca++-containing balanced electrolyte solution increased CNa × 100/GFR from 0.23 to 6.87% and reduced TRP × 100/GFR from 6.2 to 3.6 mg/min in the intact dogs; in TPTX dogs these values changed from 0.35 to 7.02% and from 6.7 to 4.6 mg/min, respectively. Ultrafilterable Ca++ did not fall in either group. When Ca++ was omitted from the loading electrolyte solution ultrafilterable Ca++ fell significantly in both groups. In the intact dogs CNa × 100/GFR increased from 0.48 to 6.26% and TRP × 100/GFR fell from 4.5 to 2.8 mg/min; in TPTX dogs these values changed from 0.48 to 8.26% and from 6.5 to 4.1 mg/min. Thus volume loading appears to inhibit TRP regardless of the presence or absence of parathyroid hormone, and whether dilutional hypocalcemia was prevented or not. It is concluded that the previously reported blunting of the phosphaturic effect of volume expansion by acute parathyroidectomy or calcium infusion may have been due to a low serum phosphorus or filtered phosphate load relative to an increased threshold or tubular reabsorptive maximum or decreased splay

Should we use closed or open infusion containers for prevention of bloodstream infections?

<p>Abstract</p> <p>Background</p> <p>Hospitalized patients in critical care settings are at risk for bloodstream infections (BSI). Most BSIs originate from a central line (CL), and they increase length of stay, cost, and mortality. Open infusion containers may increase the risk of contamination and administration-related (CLAB) because they allow the entry of air into the system, thereby also providing an opportunity for microbial entry. Closed infusion containers were designed to overcome this flaw. However, open infusion containers are still widely used throughout the world.</p> <p>The objective of the study was to determine the effect of switching from open (glass, burettes, and semi-rigid) infusion containers to closed, fully collapsible, plastic infusion containers (Viaflex^®) on the rate and time to onset of central line-associated bloodstream infections CLABs.</p> <p>Methods</p> <p>An open label, prospective cohort, active healthcare-associated infection surveillance, sequential study was conducted in four ICUs in Mexico. Centers for Disease Control National Nosocomial Infections Surveillance Systems definitions were used to define device-associated infections.</p> <p>Results</p> <p>A total of 1,096 adult patients who had a central line in place for >24 hours were enrolled. The CLAB rate was significantly higher during the open versus the closed container period (16.1 versus 3.2 CLAB/1000 central line days; RR = 0.20, 95% CI = 0.11-0.36, P < 0.0001). The probability of developing CLAB remained relatively constant in the closed container period (1.4% Days 2-4 to 0.5% Days 8-10), but increased in the open container period (4.9% Days 2-4 to 5.4% Days 8-10). The chance of acquiring a CLAB was significantly decreased (81%) in the closed container period (Cox proportional hazard ratio 0.19, P < 0.0001). Mortality was statistically significantly lower during the closed versus the open container period (23.4% versus 16.1%; RR = 0.69, 95% CI = 0.54-0.88, P < 0.01).</p> <p>Conclusions</p> <p>Closed infusion containers significantly reduced CLAB rate, the probability of acquiring CLAB, and mortality.</p

On the Whitham hierarchy: dressing scheme, string equations and additional symmetrie

A new description of the universal Whitham hierarchy in terms of a factorization problem in the Lie group of canonical transformations is provided. This scheme allows us to give a natural description of dressing transformations, string equations and additional symmetries for the Whitham hierarchy. We show how to dress any given solution and prove that any solution of the hierarchy may be undressed, and therefore comes from a factorization of a canonical transformation. A particulary important function, related to the $\tau$-function, appears as a potential of the hierarchy. We introduce a class of string equations which extends and contains previous classes of string equations considered by Krichever and by Takasaki and Takebe. The scheme is also applied for an convenient derivation of additional symmetries. Moreover, new functional symmetries of the Zakharov extension of the Benney gas equations are given and the action of additional symmetries over the potential in terms of linear PDEs is characterized

On the Whitham hierarchy: dressing scheme, string equations and additional symmetrie

A new description of the universal Whitham hierarchy in terms of a factorization problem in the Lie group of canonical transformations is provided. This scheme allows us to give a natural description of dressing transformations, string equations and additional symmetries for the Whitham hierarchy. We show how to dress any given solution and prove that any solution of the hierarchy may be undressed, and therefore comes from a factorization of a canonical transformation. A particulary important function, related to the $\tau$-function, appears as a potential of the hierarchy. We introduce a class of string equations which extends and contains previous classes of string equations considered by Krichever and by Takasaki and Takebe. The scheme is also applied for an convenient derivation of additional symmetries. Moreover, new functional symmetries of the Zakharov extension of the Benney gas equations are given and the action of additional symmetries over the potential in terms of linear PDEs is characterized

Formación universitaria en protección radiológica: nuestra experiencia en la Universidad de Málaga (España)

La Universidad de Málaga (UMA) desde 2011 tiene acreditada la formación en protección radiológica, con homologación del Consejo de Seguridad Nuclear (CSN). Desde este año, hasta nuestros días se han impartido un total de 31 cursos. La temática de los cursos impartidos han sido: director y operador de instalaciones de radiodiagnóstico médico; supervisor y operador de instalaciones radiactivas (radioterapia, medicina nuclear, laboratorio de fuentes no encapsuladas, control de procesos y técnicas analíticas), y de isótopos en el medio marino. Se han formado un total de 397 alumnos, con un 93 % de aprobados, profesionales de la enfermería, médicos, podólogos, veterinarios, odontólogos y auxiliares de higiene bucodental. Los cursos de formación constan de una parte teórica impartida por profesores del departamento de radiología y medicina física, del laboratorio de protección radiológica del CIMES y del servicio de instalación radiactiva; y de otra práctica, desarrollada en los laboratorios IRUMA de los Servicios Centrales de Investigación de la UMA, y en centros asistenciales de Radiología y Radioterapia del grupo VITHAS Salud. Todos estos cursos están integrados en titulaciones propias de la UMA, formando parte de su campus virtual (https://epropias.cv.uma.es/), basado en una plataforma Moodle. Esto supone un total de 159 créditos ECTS impartidos, en cursos de formación superior y de extensión universitaria. Por lo tanto, obtienen una doble titulación integrada

Estimación de niveles de referencia de dosis y contribución a la dosis poblacional de las TC en España

La Tomografía Computarizada (TC) es una de las pruebas de radiodiagnóstico que mayor dosis de radiación emite. En los últimos años ha aumentado mucho su uso en la práctica médica y, por ello, hemos querido estudiar en este trabajo la dosis de radiación procedente de los TC que recibe la población en España Tras analizar los datos recopilados de los centros hospitalarios de todas las Comunidades Autónomas Españolas y basándonos en los principales tipos de procedimiento de TC referenciados en el Report Radiation Protection nº154, hemos estimado los valores de referencia de dosis (DRLs) (3ºquartil) para los procedimientos que mayor contribución aportan a la dosis colectiva, por encima de 1000 hombre-Sv. Se ha tenido en cuenta la dosis por longitud (DLP). Los DRLs estimados han sido (mGy*cm) son TC cabeza 450, TC tórax 490, TC columna 690, TC abdomen 750, TC pelvis 780 y TC tronco 890. Los resultados obtenidos confirmaron que más de la mitad de la Dosis Efectiva Colectiva (dosis poblacional), el 66%, depende de las Tomografías Computarizadas, 645,23 mSv/1000 habitantes para un total global de todos los estudios con RX de 969,35 mSv/1000 habitantes. Por lo tanto, es importante intentar disminuir la exposición de la población a la radiación, haciendo un buen uso de las nuevas tecnologías e incluyendo la Protección Radiológica en la práctica médica

Computer simulations of VANETs using realistic city topologies

Researchers in vehicular ad hoc networks (VANETs) commonly use simulation to test new algorithms and techniques. This is the case because of the high cost and labor involved in deploying and testing vehicles in real outdoor scenarios. However, when determining the factors that should be taken into account in these simulations, some factors such as realistic road topologies and presence of obstacles are rarely addressed. In this paper, we first evaluate the packet error rate (PER) through actual measurements in an outdoor road scenario, and deduce a close model of the PER for VANETs. Secondly, we introduce a topology-based visibility scheme such that road dimension and geometry can be accounted for, in addition to line-of-sight. We then combine these factors to determine when warning messages (i.e., messages that warn drivers of danger and hazards) are successfully received in a VANET. Through extensive simulations using different road topologies, city maps, and visibility schemes, we show these factors can impact warning message dissemination time and packet delivery rate.This work was partially supported by the Ministerio de Educacion y Ciencia, Spain, under Grant TIN2011-27543-C03-01, and by the Diputacion General de Aragon, under Grant "subvenciones destinadas a la formacion y contratacion de personal investigador".Martínez, FJ.; Fogue, M.; Toh, C.; Cano Escribá, JC.; Tavares De Araujo Cesariny Calafate, CM.; Manzoni, P. (2013). Computer simulations of VANETs using realistic city topologies. Wireless Personal Communications. 69(2):639-663. https://doi.org/10.1007/s11277-012-0594-6S639663692Martinez F. J., Toh C.-K., Cano J.-C., Calafate C. T., Manzoni P. (2011) A survey and comparative study of simulators for vehicular ad hoc networks (VANETs). Wireless Communications and Mobile Computing Journal 11(7): 813–828Toh C.-K. 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J., Fogue, M., Coll, M., Cano, J.-C., Calafate, C. T., & Manzoni, P. (2010). Assessing the impact of a realistic radio propagation model on VANET scenarios using real maps. In 9th IEEE international symposium on network computing and applications (NCA), Boston, USA, pp. 132–139.Fall, K., & Varadhan, K. (2000). “ns notes and documents,” The VINT project. UC Berkeley, LBL, USC/ISI, and Xerox PARC, February 2000. Available at http://www.isi.edu/nsnam/ns/ns-documentation.html .Marinoni, S., & Kari, H. H. (2006). Ad hoc routing protocol performance in a realistic environment. In Proceedings of the international conference on networking, international conference on systems and international conference on mobile communications and learning technologies (ICN/ICONS/MCL 2006), Washington, DC, USA.Mahajan, A., Potnis, N., Gopalan, K., & Wang, A. (2007). Modeling VANET deployment in urban settings. In International workshop on modeling analysis and simulation of wireless and mobile systems (MSWiM 2007), Crete Island, Greece.Suriyapaiboonwattana, K., Pornavalai, C., & Chakraborty, G. (2009). An adaptive alert message dissemination protocol for VANET to improve road safety. In IEEE intlernational conference on fuzzy systems, 2009. FUZZ-IEEE 2009, pp. 1639–1644.Bako, B., Schoch, E., Kargl, F., & Weber, M. (2008). Optimized position based gossiping in VANETs. In Vehicular technology conference, 2008. VTC 2008-Fall. IEEE 68th, pp. 1–5.Martinez, F. J., Cano, J.-C., Calafate, C. T., & Manzoni, P. (2008). Citymob: A mobility model pattern generator for VANETs. In IEEE vehicular networks and applications workshop (Vehi-Mobi, held with ICC), Beijing, China.Torrent-Moreno, M., Santi, P., & Hartenstein, H. (2007). Inter-vehicle communications: Assessing information dissemination under safety constraints. 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Benchmarking of single‐virus genomics: a new tool for uncovering the virosphere

Metagenomics and single‐cell genomics have enabled the discovery of relevant uncultured microbes. Recently, single‐virus genomics (SVG), although still in an incipient stage, has opened new avenues in viral ecology by allowing the sequencing of one single virus at a time. The investigation of methodological alternatives and optimization of existing procedures for SVG is paramount to deliver high‐quality genomic data. We report a sequencing dataset of viral single‐amplified genomes (vSAGs) from cultured and uncultured viruses obtained by applying different conditions in each SVG step, from viral preservation and novel whole‐genome amplification (WGA) to sequencing platforms and genome assembly. Sequencing data showed that cryopreservation and mild fixation were compatible with WGA, although fresh samples delivered better genome quality data. The novel TruPrime WGA, based on primase‐polymerase features, and WGA‐X employing a thermostable phi29 polymerase, were proven to be with sufficient sensitivity in SVG. The Oxford Nanopore (ON) sequencing platform did not provide a significant improvement of vSAG assembly compared to Illumina alone. Finally, the SPAdes assembler performed the best. Overall, our results represent a valuable genomic dataset that will help to standardized and advance new tools in viral ecology.This work has been supported by Gordon and Betty Moore Foundation (grant 5334) and Spanish Ministry of Economy and Competitiveness (refs CGL2013‐40564‐R, RTI2018‐094248‐B‐I00 and SAF2013‐49267‐EXP). Work at CRG, BIST and UPF was in part funded by the Spanish Ministry of Economy and Competitiveness, ‘Centro de Excelencia Severo Ochoa 2013‐2017’ and the Spanish Ministry of Economy and Competitiveness, ‘Centro de Excelencia Maria de Maeztu 2016‐2019’