779 research outputs found

    The Effects of Gender and Self Construal on Perception of Racism

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    When looking into the idea of if one\u27s gender and their self-construal has an effect on how they perceive racism, we hypothesize that women will take a more interdependent self-construal and men will take a more independent self-construal. Based on how they identify, we believe that those in the interdependent condition will perceive more racism and those in the independent condition will perceive less racism

    Sex Differences in the Relationship Between Planum Temporale Asymmetry and Corpus Callosum Morphology in Chimpanzees (\u3cem\u3ePan troglodytes\u3c/em\u3e): A Combined MRI and DTI Analysis

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    Increases brain size has been hypothesized to be inversely associated with the expression of behavioral and brain asymmetries within and between species. We tested this hypothesis by analyzing the relation between asymmetries in the planum temporale (PT) and different measures of the corpus callosum (CC) including surface area, streamline count as measured from diffusion tensor imaging, fractional anisotropy values and the ratio in the number of fibers to surface area in a sample of chimpanzees. We found that chimpanzees with larger PT asymmetries in absolute terms had smaller CC surface areas, fewer streamlines and a smaller ratio of fibers to surface area. These results were largely specific to male but not female chimpanzees. Our results partially support the hypothesis that brain asymmetries are linked to variation in corpus callosum morphology, although these associations may be sex-dependent

    Hand Preference for Coordinated Bimanual Actions in 777 Great Apes: Implications for the Evolution of Handedness in Hominins

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    Whether or not nonhuman primates exhibit population-level handedness remains a topic of considerable scientific debate. Here, we examined handedness for coordinated bimanual actions in a sample of 777 great apes including chimpanzees, bonobos, gorillas, and orangutans. We found population-level right-handedness in chimpanzees, bonobos and gorillas, but left-handedness in orangutans. Directional biases in handedness were consistent across independent samples of apes within each genus. We suggest that, contrary to previous claims, population-level handedness is evident in great apes but differs among species as a result of ecological adaptations associated with posture and locomotion. We further suggest that historical views of nonhuman primate handedness have been too anthropocentric, and we advocate for a larger evolutionary framework for the consideration of handedness and other aspects of hemispheric specialization among primates

    The Multifragmentation Freeze--Out Volume in Heavy Ion Collisions

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    The reduced velocity correlation function for fragments from the reaction Fe + Au at 100 A~MeV bombarding energy is investigated using the dynamical--statistical approach QMD+SMM and compared to experimental data to extract the Freeze--Out volume assuming simultaneous multifragmentation.Comment: 8 pages; 3 uuencoded figures available with figures command, LateX, UCRL-J-1157

    A large geometric distortion in the first photointermediate of rhodopsin, determined by double-quantum solid-state NMR

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    Double-quantum magic-angle-spinning NMR experiments were performed on 11,12-C-13(2)-retinylidene-rhodopsin under illumination at low temperature, in order to characterize torsional angle changes at the C11-C12 photoisomerization site. The sample was illuminated in the NMR rotor at low temperature (similar to 120 K) in order to trap the primary photointermediate, bathorhodopsin. The NMR data are consistent with a strong torsional twist of the HCCH moiety at the isomerization site. Although the HCCH torsional twist was determined to be at least 40A degrees, it was not possible to quantify it more closely. The presence of a strong twist is in agreement with previous Raman observations. The energetic implications of this geometric distortion are discussed

    Resistencia a los antihelmínticos en bovinos del nordeste de Corrientes (Argentina)

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    El objetivo del trabajo fue determinar la prevalencia de la resistencia a los antiparasitarios contra los nematodes gastrointestinales de bovinos en el nordeste de Corrientes. El área de estudio comprendió 4 establecimientos ganaderos de los departamentos Ituzaingó y Santo Tomé. El periodo de estudio abarcó de marzo de 2014 a agosto de 2016. La unidad de análisis fue el ternero destete. El método utilizado fue el test de reducción del conteo de huevos. La prevalencia de la resistencia antihelmíntica a la ivermectina en los 4 establecimientos ganaderos muestreados en este estudio fue del 100% y para el benzimidazol fue del 25%. Los géneros parasitarios resistentes a la ivermectina fueron Haemonchus y Cooperia. Estos resultados demuestran un aumento de la resistencia antihelmíntica si se comparan con estudios previos realizados en otros lugares del país

    Identificación de nematodos gastrointestinales en búfalos faenados en un frigorífico de Corrientes, Argentina

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    The objective of this work was to identify and quantify the adult specimens of gastrointestinal nematodes in buffaloes slaughtered in Virasoro (Corrientes, Argentina) by means of necropsy of the digestive tract, and through coprological studies, in order to correlate them with the count of eggs per gram of fecal stool and the proportion of parasite genera of third stage larvae of stool culture. A total of 4 necropsies corresponding to young male buffaloes were carried out, of which 50% presented adult specimens of Trichostrongylus sp and Haemonchus sp located only in the abomasum. In the coprological studies, 75% of the samples presented counts of egg per gram of fecal stool, with only 2 cases with the identification of third stage larvae of Haemonchus sp in stool cultures.El objetivo del trabajo fue identificar y cuantificar los ejemplares adultos de nematodos gastrointestinales en los búfalos faenados en el frigorífico de Virasoro (Corrientes) mediante la necropsia parasitaria del tubo digestivo y, por intermedio de estudios coprológicos, correlacionarlos con el recuento de huevos por gramo de materia fecal y la proporción de géneros parasitarios de larvas de tercer estadio de los coprocultivos. Se realizaron en total 4 necropsias parasitarias que correspondieron a búfalos machos jóvenes, de los cuales el 50% presentó ejemplares adultos de Trichostrongylus sp y Haemonchus sp ubicados solamente en el abomaso. En los estudios coprológicos, el 75% de las muestras presentaron recuentos de huevos por gramo de materia fecal, de los cuales únicamente en dos casos se pudieron identificar larvas de tercer estadio de Haemonchus sp en los coprocultivos

    Toward An Understanding Of The Retinal Chromophore In Rhodopsin Mimics

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    Recently, a rhodopsin protein mimic was constructed by combining mutants of the cellular retinoic acid binding protein II (CRABPII) with an all-trans retinal chromophore. Here, we present a combine computational quantum mechanics/molecular mechanics (QM/MM) and experimental ultrafast kinetic study of CRABPII. We employ the QM/MM models to study the absorption (lambda(a)(max)), fluorescence (lambda(f)(max)), and reactivity of a CRABPII triple mutant incorporating the all-trans protonated chromophore (PSB-KLE-CRABPII). We also study the spectroscopy of the same mutant incorporating the unprotonated chromophore and of another double mutant incorporating the neutral unbound retinal molecule held inside the pocket. Finally, for PSB-KLE-CRABPII, stationary fluorescence spectroscopy and ultrafast transient absorption spectroscopy resolved two different evolving excited state populations which were computationally assigned to distinct locally excited and charge-transfer species. This last species is shown to evolve along reaction paths describing a facile isomerization of the biologically relevant 11-cis and 13-cis double bonds. This work represents a first exploratory attempt to model and study these artificial protein systems. It also indicates directions for improving the QM/MM models so that they could be more effectively used to assist the bottom-up design of genetically encodable probes and actuators employing the retinal chromophore

    Antiretroviral Drug Resistance Testing in Adult HIV-1 Infection: 2008 Recommendations of an International AIDS Society-USA Panel

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    Resistance to antiretroviral drugs remains an important limitation to successful human immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment outcomes for infected individuals. The availability of new drugs from various classes, standardization of resistance assays, and the development of viral tropism tests necessitate new guidelines for resistance testing. The International AIDS Society-USA convened a panel of physicians and scientists with expertise in drug-resistant HIV-1, drug management, and patient care to review recently published data and presentations at scientific conferences and to provide updated recommendations. Whenever possible, resistance testing is recommended at the time of HIV infection diagnosis as part of the initial comprehensive patient assessment, as well as in all cases of virologic failure. Tropism testing is recommended whenever the use of chemokine receptor 5 antagonists is contemplated. As the roll out of antiretroviral therapy continues in developing countries, drug resistance monitoring for both subtype B and non-subtype B strains of HIV will become increasingly importan
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