A wind-tunnel investigation of sonic-boom pressure distributions of bodies of revolution at Mach 2.96, 3.83, and 4.63

Measurements of sonic boom pressure distribution of bodies of revolution at Mach 2.96, 3.83, and 4.63 in Unitary Plan wind tunne

Factorizing Numbers with the Gauss Sum Technique: NMR Implementations

Several physics-based algorithms for factorizing large number were recently published. A notable recent one by Schleich et al. uses Gauss sums for distinguishing between factors and non-factors. We demonstrate two NMR techniques that evaluate Gauss sums and thus implement their algorithm. The first one is based on differential excitation of a single spin magnetization by a cascade of RF pulses. The second method is based on spatial averaging and selective refocusing of magnetization for Gauss sums corresponding to factors. All factors of 16637 and 52882363 are successfully obtained.Comment: 4 pages, 4 figures; Abstract and Conclusion are slightly modified. References added and formatted with Bibte

Observation of coherent π0\pi^0 electroproduction on deuterons at large momentum transfer

The first experimental results for coherent $\pi^0$-electroproduction on the deuteron, $e+d\to e+d +\pi^0$, at large momentum transfer, are reported. The experiment was performed at Jefferson Laboratory at an incident electron energy of 4.05 GeV. A large pion production yield has been observed in a kinematical region for 1.1$<Q^2<$1.8 GeV$^2$, from threshold to 200 MeV excitation energy in the $d\pi^0$ system. The $Q^2$-dependence is compared with theoretical predictions.Comment: 26 page

SDSSJ143244.91+301435.3 at VLBI: a compact radio galaxy in a narrow-line Seyfert 1

We present VLBI observations, carried out with the European Very Long Baseline Interferometry Network (EVN), of SDSSJ143244.91+301435.3, a radio-loud narrow-line Seyfert 1 (RLNLS1) characterized by a steep radio spectrum. The source, compact at Very Large Array (VLA) resolution, is resolved on the milliarcsec scale, showing a central region plus two extended structures. The relatively high brightness temperature of all components (5x10^6-1.3x10^8 K) supports the hypothesis that the radio emission is non-thermal and likely produced by a relativistic jet and/or small radio lobes. The observed radio morphology, the lack of a significant core and the presence of a low frequency (230 MHz) spectral turnover are reminiscent of the Compact Steep Spectrum sources (CSS). However, the linear size of the source (~0.5kpc) measured from the EVN map is lower than the value predicted using the turnover/size relation valid for CSS sources (~6kpc). This discrepancy can be explained by an additional component not detected in our observations, accounting for about a quarter of the total source flux density, combined to projection effects. The low core-dominance of the source (CD<0.29) confirms that SDSSJ143244.91+301435.3 is not a blazar, i.e. the relativistic jet is not pointing towards the observer. This supports the idea that SDSSJ143244.91+301435.3 may belong to the "parent population" of flat-spectrum RLNLS1 and favours the hypothesis of a direct link between RLNLS1 and compact, possibly young, radio galaxies.Comment: 8 pages, 3 figures, accepted for publication in MNRA

Continued investigation of LDEF's structural frame and thermal blankets by the Meteoroid and Debris Special Investigation Group

This report focuses on the data acquired by detailed examination of LDEF intercostals, 68 of which are now in possession of the Meteoroid and Debris Special Investigation Group (M&D SIG) at JSC. In addition, limited data will be presented for several small sections from the A0178 thermal control blankets that were examined/counted prior to being shipped to Principal Investigators (PI's) for scientific study. The data presented here are limited to measurements of crater and penetration-hole diameters and their frequency of occurrence which permits, yet also constrains, more model-dependent, interpretative efforts. Such efforts will focus on the conversion of crater and penetration-hole sizes to projectile diameters (and masses), on absolute particle fluxes, and on the distribution of particle-encounter velocities. These are all complex issues that presently cannot be pursued without making various assumptions which relate, in part, to crater-scaling relationships, and to assumed trajectories of natural and man-made particle populations in LEO that control the initial impact conditions

Effective Field Theories

Effective field theories encode the predictions of a quantum field theory at low energy. The effective theory has a fairly low ultraviolet cutoff. As a result, loop corrections are small, at least if the effective action contains a term which is quadratic in the fields, and physical predictions can be read straight from the effective Lagrangean. Methods will be discussed how to compute an effective low energy action from a given fundamental action, either analytically or numerically, or by a combination of both methods. Basically,the idea is to integrate out the high frequency components of fields. This requires the choice of a "blockspin",i.e. the specification of a low frequency field as a function of the fundamental fields. These blockspins will be the fields of the effective field theory. The blockspin need not be a field of the same type as one of the fundamental fields, and it may be composite. Special features of blockspins in nonabelian gauge theories will be discussed in some detail. In analytical work and in multigrid updating schemes one needs interpolation kernels \A from coarse to fine grid in addition to the averaging kernels $C$ which determines the blockspin. A neural net strategy for finding optimal kernels is presented. Numerical methods are applicable to obtain actions of effective theories on lattices of finite volume. The constraint effective potential) is of particular interest. In a Higgs model it yields the free energy, considered as a function of a gauge covariant magnetization. Its shape determines the phase structure of the theory. Its loop expansion with and without gauge fields can be used to determine finite size corrections to numerical data.Comment: 45 pages, 9 figs., preprint DESY 92-070 (figs. 3-9 added in ps format

Theoretical Analysis of Acceptance Rates in Multigrid Monte Carlo

We analyze the kinematics of multigrid Monte Carlo algorithms by investigating acceptance rates for nonlocal Metropolis updates. With the help of a simple criterion we can decide whether or not a multigrid algorithm will have a chance to overcome critial slowing down for a given model. Our method is introduced in the context of spin models. A multigrid Monte Carlo procedure for nonabelian lattice gauge theory is described, and its kinematics is analyzed in detail.Comment: 7 pages, no figures, (talk at LATTICE 92 in Amsterdam

CDKN1C/p57kip2 Is a Candidate Tumor Suppressor Gene in Human Breast Cancer

BACKGROUND. CDKN1C (also known as p57KIP2) is a cyclin-dependent kinase inhibitor previously implicated in several types of human cancer. Its family members (CDKN1A/p21CIP1 and B/p27KIP1) have been implicated in breast cancer, but information about CDKN1C's role is limited. We hypothesized that decreased CDKN1C may be involved in human breast carcinogenesis in vivo. METHODS. We determined rates of allele imbalance or loss of heterozygosity (AI/LOH) in CDKN1C, using an intronic polymorphism, and in the surrounding 11p15.5 region in 82 breast cancers. We examined the CDKN1C mRNA level in 10 cancers using quantitative real-time PCR (qPCR), and the CDKN1C protein level in 20 cancers using immunohistochemistry (IHC). All samples were obtained using laser microdissection. Data were analyzed using standard statistical tests. RESULTS. AI/LOH at 11p15.5 occurred in 28/73 (38%) informative cancers, but CDKN1C itself underwent AI/LOH in only 3/16 (19%) cancers (p = ns). In contrast, CDKN1C mRNA levels were reduced in 9/10 (90%) cancers (p < 0.0001), ranging from 2–60% of paired normal epithelium. Similarly, CDKN1C protein staining was seen in 19/20 (95%) cases' normal epithelium but in only 7/14 (50%) cases' CIS (p < 0.004) and 5/18 (28%) cases' IC (p < 0.00003). The reduction appears primarily due to loss of CDKN1C expression from myoepithelial layer cells, which stained intensely in 17/20 (85%) normal lobules, but in 0/14 (0%) CIS (p < 0.00001). In contrast, luminal cells displayed less intense, focal staining fairly consistently across histologies. Decreased CDKN1C was not clearly associated with tumor grade, histology, ER, PR or HER2 status. CONCLUSION. CDKN1C is expressed in normal epithelium of most breast cancer cases, mainly in the myothepithelial layer. This expression decreases, at both the mRNA and protein level, in the large majority of breast cancers, and does not appear to be mediated by AI/LOH at the gene. Thus, CDKN1C may be a breast cancer tumor suppressor.Department of Defense Breast Cancer Research Program (DAMD 17-99-1-9573); National Institutes of Health PHS (CA081078); LaPann Fun