Genus Ramaria in the Eastern Himalaya: subgenus Laeticolora-I

In this paper an account of 11 taxa of the genus Ramaria (Fr.) Bonorden collected from different localities in the eastern Himalaya and adjoining hills is given. Of the taxa included, Ramaria conjunctipes, Ramaria araiospora var. rubella, Ramaria xanthosperma, Ramaria rubribrunnescens, Ramaria flavigelatinosa, Ramaria flavigelatinosa var.carnisalmonea and Ramaria gelatiniaurantia are new records for the Himalayas; while Ramaria rubrogelatinosa, Ramaria brevispora, Ramaria brevispora var. albida and Ramaria perbrunnea were not known earlier from the eastern Himalaya

Condensed -heterocyclics: Part XXVIII - Synthesis of substituted naphtho[1,2-b]thiapyrano[3,4-b]quinoxaline and its 8-aza analogues

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Teratogenic Effect of Lamotrigine on Developing Liver of Swiss Albino Mice

Abstract: The aim of present study was to observe the noxious effect of Lamotrigine (LTG

Physicochemical characterization and improved in vitro dissolution performance of diacerein solid dispersions with PVP K30

Solid dispersions (SDs) of poorly water soluble diacerein were prepared with polyvinylpyrrolidone K30 at drug to polymer ratios of 1:1, 1:3 and 1:5 w/w utilizing kneading technique. Physical mixture (PM) was prepared at drug to polymer ratio of 1:5 w/w for comparison. All formulations were further characterized by TLC, DSC, XRPD, SEM and dissolution studies. TLC indicated an absence of chemical interaction between drug and polymer. A prominent decrease in the crystallinity was accounted for diacerein in binary systems from XRPD data. DSC thermograms revealed a uniform molecular dispersion and generation of amorphous entities of drug accompanied by loss of crystalline and irregular shape with distinct changes in surface morphological features of diacerein detected in SEM photomicrographs. The drug dissolution properties of SDs were significantly improved (DP2: 95.87-100%) in comparison to crystalline diacerein and PM suggesting suitability of kneading method for improving the release rate properties of diacerein.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Physicochemical characterization and improved in vitro dissolution performance of diacerein solid dispersions with PVP K30

Solid dispersions (SDs) of poorly water soluble diacerein were prepared with polyvinylpyrrolidone K30 at drug to polymer ratios of 1:1, 1:3 and 1:5 w/w utilizing kneading technique. Physical mixture (PM) was prepared at drug to polymer ratio of 1:5 w/w for comparison. All formulations were further characterized by TLC, DSC, XRPD, SEM and dissolution studies. TLC indicated an absence of chemical interaction between drug and polymer. A prominent decrease in the crystallinity was accounted for diacerein in binary systems from XRPD data. DSC thermograms revealed a uniform molecular dispersion and generation of amorphous entities of drug accompanied by loss of crystalline and irregular shape with distinct changes in surface morphological features of diacerein detected in SEM photomicrographs. The drug dissolution properties of SDs were significantly improved (DP2: 95.87-100%) in comparison to crystalline diacerein and PM suggesting suitability of kneading method for improving the release rate properties of diacerein.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Huge field-effect surface charge injection and conductance modulation in metallic thin films by electrochemical gating

The field-effect technique, popular thanks to its application in common field-effect transistors, is here applied to metallic thin films by using as a dielectric a novel polymer electrolyte solution. The maximum injected surface charge, determined by a suitable modification of a classic method of electrochemistry called double-step chronocoulometry, reached more than 4 × 10 15 charges/cm 2 . At room temperature, relative variations of resistance up to 8%, 1.9% and 1.6% were observed in the case of gold, silver and copper, respectively and, if the films are thick enough (≥25 nm), results can be nicely explained within a free-electron model with parallel resistive channels. The huge charge injections achieved make this particular field-effect technique very promising for a vast variety of materials such as unconventional superconductors, graphene and 2D-like materials. © 2012 Elsevier B.V

Temperature Dependence of Electric Transport in Few-layer Graphene under Large Charge Doping Induced by Electrochemical Gating

The temperature dependence of electric transport properties of single-layer and few-layer graphene at large charge doping is of great interest both for the study of the scattering processes dominating the conductivity at different temperatures and in view of the theoretically predicted possibility to reach the superconducting state in such extreme conditions. Here we present the results obtained in 3-, 4- and 5-layer graphene devices down to 3.5 K, where a large surface charge density up to about 6.8·1014 cm-2 has been reached by employing a novel polymer electrolyte solution for the electrochemical gating. In contrast with recent results obtained in single-layer graphene, the temperature dependence of the sheet resistance between 20 K and 280 K shows a low-temperature dominance of a T2 component - that can be associated with electron-electron scattering - and, at about 100 K, a crossover to the classic electron-phonon regime. Unexpectedly, this crossover does not show any dependence on the induced charge density, i.e. on the large tuning of the Fermi energy

Examining inequalities in uptake of maternal health care and choice of provider in underserved urban areas of Mumbai, India: A mixed methods study

Background: Discussions of maternity care in developing countries tend to emphasise service uptake and overlook choice of provider. Understanding how families choose among health providers is essential to addressing inequitable access to care. Our objectives were to quantify the determinants and choice of maternity care provider in Mumbai's informal urban settlements, and to explore the reasons underlying their choices. Methods: The study was conducted in informal urban communities in eastern Mumbai. We developed regression models using data from a census of married women aged 15-49 to test for associations between maternal characteristics and uptake of care and choice of provider. We then conducted seven focus group discussions and 16 in-depth interviews with purposively selected participants, and used grounded theory methods to examine the reasons for their choices. Results: Three thousand eight hundred forty-eight women who had given birth in the preceding 2 years were interviewed in the census. The odds of institutional prenatal and delivery care increased with education, economic status, and duration of residence in Mumbai, and decreased with parity. Tertiary public hospitals were the commonest site of care, but there was a preference for private hospitals with increasing socio-economic status. Women were more likely to use tertiary public hospitals for delivery if they had fewer children and were Hindu. The odds of delivery in the private sector increased with maternal education, wealth, age, recent arrival in Mumbai, and Muslim faith. Four processes were identified in choosing a health care provider: exploring the options, defining a sphere of access, negotiating autonomy, and protective reasoning. Women seeking a positive health experience and outcome adopted strategies to select the best or most suitable, accessible provider. Conclusions: In Mumbai's informal settlements, institutional maternity care is the norm, except among recent migrants. Poor perceptions of primary public health facilities often cause residents to bypass them in favour of tertiary hospitals or private sector facilities. Families follow a complex selection process, mediated by their ability to mobilise economic and social resources, and a concern for positive experiences of health care and outcomes. Health managers must ensure quality services, a functioning regulatory mechanism, and monitoring of provider behaviour

A Comparison of Online and In-Person Activity Engagement: The Case of Shopping and Eating Meals

You're viewing a past Journal from the Good Systems Grand Challenge team at The University of Texas at Austin from February 2020.Office of the VP for Researc

Explaining context, mechanism and outcome in adult community mental health crisis care: a realist evidence synthesis

Mental health crises cause significant distress and disruption to the lives of individuals and their families. Community crisis care systems are complex, often hard to navigate and poorly understood. This realist evidence synthesis aimed to explain how, for whom and in what circumstances community mental health crisis services for adults work to resolve crises and is reported according to RAMESES guidelines. Using realist methodology, initial programme theories were identified and then tested through iterative evidence searching across 10 electronic databases, four expert stakeholder consultations and n = 20 individual interviews. 45 relevant records informed the three initial programme theories, and 77 documents, were included in programme theory testing. 39 context, mechanism, outcome configurations were meta-synthesized into three themes: (1) The gateway to urgent support; (2) Values based crisis interventions and (3) Leadership and organizational values. Fragmented cross-agency responses exacerbated staff stress and created barriers to access. Services should focus on evaluating interagency working to improve staff role clarity and ensure boundaries between services are planned for. Organizations experienced as compassionate contributed positively to perceived accessibility but relied on compassionate leadership. Attending to the support needs of staff and the proximity of leaders to the front line of crisis care are key. Designing interventions that are easy to navigate, prioritize shared decision-making and reduce the risk of re-traumatizing people is a priority