The use of highmolecular-weight hyaluronic acid in the treatment of osteoarthritis

Osteoarthritis (OA) is one of the most common diseases of the musculoskeletal system, affecting mainly people of old age. The management of OA requires combined therapy using pharmaceutical and nonpharmacological modalities, including hyaluronic acid (HA). Hylans are highmolecular-weight (HMW) HA derivatives. The use of hylans results in reducing pain and stiffness and in improving functional activity. Their efficacy is comparable with that of lowmolecular-weight HA. Intraarticular injection of HMW HA derivatives is safe and effective for treating OA

Tagging the pion quark structure in QCD

We combine the constraints on the pion quark structure available from perturbative QCD, nonperturbative QCD (nonlocal QCD sum rules and light cone sum rules) with the analysis of current data on F_{\pi\gamma\gamma^*}(Q^2), including recent high-precision lattice calculations of the second moment of the pion's distribution amplitude. We supplement these constraints with those extracted from the renormalon approach by means of the twist-four contributions to the pion distribution amplitude in order to further increase stability with respect to related theoretical uncertainties. We show which regions in the space of the first two non-trivial Gegenbauer coefficients a_2 and a_4 of all these constraints overlap, tagging this way the pion structure to the highest degree possible at present.Comment: V1: 6 pages, 2 figures, 1 table. V2: Two references added with corresponding insertions in the text. Matches version published in PR

Rare decay pi0 -> e+e-: theory confronts KTeV data

Within the dispersive approach to the amplitude of the rare decay pi0 -> e+e- the nontrivial dynamics is contained only in the subtraction constant. We express this constant, in the leading order in (m_e/\Lambda)^2 perturbative series, in terms of the inverse moment of the pion transition form factor given in symmetric kinematics. By using the CELLO and CLEO data on the pion transition form factor given in asymmetric kinematics the lower bound on the decay branching ratio is found. The restrictions following from QCD allow us to make a quantitative prediction for the branching B(pi0 -> e+e-) =(6.2\pm 0.1)*10^{-8} which is 3\sigma below the recent KTeV measurement. We confirm our prediction by using the quark models and phenomenological approaches based on the vector meson dominance. The decays \eta -> l^+l^- are also discussed.Comment: 7 pages, 1 figur

Применение высокомолекулярных препаратов гиалуроновой кислоты в терапии остеоартрита

Osteoarthritis (OA) is one of the most common diseases of the musculoskeletal system, affecting mainly people of old age. The management of OA requires combined therapy using pharmaceutical and nonpharmacological modalities, including hyaluronic acid (HA). Hylans are highmolecular-weight (HMW) HA derivatives. The use of hylans results in reducing pain and stiffness and in improving functional activity. Their efficacy is comparable with that of lowmolecular-weight HA. Intraarticular injection of HMW HA derivatives is safe and effective for treating OA.Остеоартрит (ОА) является одним из самых распространенных заболеваний скелетно-мышечной системы, поражающих преимущественно лиц старших возрастных групп. Для лечения ОА применяют комбинированную терапию с использованием фармакологических и нефармакологических методов, включая препараты гиалуроновой кислоты. Гиланы представляют собой высокомолекулярные (ВМ) производные гиалуроновой кислоты (ГНК). Применение гиланов сопровождается уменьшением боли, скованности и улучшением функциональной активности. Их эффективность сопоставима с таковой низкомолекулярных препаратов ГНК. Внутрисуставное введение ВМ производных ГНК является безопасным и эффективным методом лечения ОА

CSU FIRE 2 cirrus field experiment: Description of field deployment phase

The Colorado State University (CSU) surface observing systems are described. These systems were deployed at the Parsons, Kansas site during the FIRE 2 Cirrus Special Observing Period (SOP) from 13 Nov. - 7 Dec. 1991. The geographical coordinates of the site containing most of the CSU instrumentation are 37 deg. 18 min N. latitude and 96 deg. 30 min. W. longitude; site elevation was 269 meters. In addition, one surface meteorological and broadband flux observing site was maintained at the Tri City Airport which is approximately 18 miles due west of Parsons (37 deg. 20 min. N. latitude, 95 deg. 30 min. 30 sec. W. longitude). A map of the locations of the CSU deployment sites is presented. At the main Parsons site, the instrumentation was located directly adjacent to and north of a lake. Under most cirrus observing conditions, when the wing had a significant southernly component, the lake was upwind of the observing site. The measurements and observations collected during the experiment are listed. These measurements may be grouped into five categories: surface meteorology; infrared spectral and broadband measurements; solar spectral and broadband measurements; upper air measurements; and cloud measurements. A summary of observations collected at the Parsons site during the SOP are presented. The wind profiler, laser ceilometer, surface meteorology and surface broadband radiation instrumentation were operated on a continuous basis. All other systems were operated on an 'on demand' basis when cloud conditions merited the collection of data

Use of Technogenic Silica Fume and Brown Coal Semi-Coke in the Technology of Silicon Carbide

The paper describes thermodynamic experiments to determine the optimal temperature and time modes for the carbide production process from the briquette charge comprising silica fume and brown coal semi-coke, conditions for chemical enriching of silicon carbide, its phase, chemical and granulometric compositions and particle morphology

The gluon content of the η\eta and η′\eta^{\prime} mesons and the ηγ\eta\gamma, η′γ\eta^{\prime}\gamma electromagnetic transition form factors

We compute power-suppressed corrections to the \eta\gamma and \eta^{\prime}\gamma transition form factors Q^2F_{\eta(\eta^{\prime})\gamma}(Q^2) arising from the end point regions x \to 0,1 by employing the infrared-renormalon approach. The contribution to the form factors from the quark and gluon content of the \eta,\eta^{\prime} mesons is taken into account using for the \eta-\eta^{\prime} mixing the SU_f(3) singlet \eta_1 and octet \eta_8 basis. The theoretical predictions obtained this way are compared with the corresponding CLEO data and restrictions on the input parameters (Gegenbauer coefficients) B_2^q(\eta_1), B_2^g(\eta_1), and B_2^q(\eta_8) in the distribution amplitudes for the \eta_1,\eta_8 states with one nonasymptotic term are deduced. Comparison is made with the results from QCD perturbation theory.Comment: 25 pages, RevTeX4 used. 9 figures as EPS files. Text significantly changed to include variation of theoretical parameters. Figures modified. Corrected typo in equation (34) and trivial mistake in $\beta_1$-coefficient. References added. Conclusions unchange

Photon distribution amplitudes and light-cone wave functions in chiral quark models

The leading- and higher-twist distribution amplitudes and light-cone wave functions of real and virtual photons are analyzed in chiral quark models. The calculations are performed in the nonlocal quark model based on the instanton picture of QCD vacuum, as well as in the spectral quark model and the Nambu--Jona-Lasinio model with the Pauli-Villars regulator, which both treat interaction of quarks with external fields locally. We find that in all considered models the leading-twist distribution amplitudes of the real photon defined at the quark-model momentum scale are constant or remarkably close to the constant in the $x$ variable, thus are far from the asymptotic limit form. The QCD evolution to higher momentum scales is necessary and we carry it out at the leading order of the perturbative theory for the leading-twist amplitudes. We provide estimates for the magnetic susceptibility of the quark condensate $\chi_m$ and the coupling $f_{3\gamma}$, which in the nonlocal model turn out to be close to the estimates from QCD sum rules. We find the higher-twist distribution amplitudes at the quark model scale and compare them to the Wandzura-Wilczek estimates. In addition, in the spectral model we evaluate the distribution amplitudes and light-cone wave functions of the $\rho$-meson.Comment: 24 pages, 15 figure

Light Cone Sum Rules for gamma* N -> Delta Transition Form Factors

A theoretical framework is suggested for the calculation of gamma* N -> Delta transition form factors using the light-cone sum rule approach. Leading-order sum rules are derived and compared with the existing experimental data. We find that the transition form factors in a several GeV region are dominated by the ``soft'' contributions that can be thought of as overlap integrals of the valence components of the hadron wave functions. The ``minus'' components of the quark fields contribute significantly to the result, which can be reinterpreted as large contributions of the quark orbital angular momentumComment: 38 pages, 10 figures; some typos fixed and references added, to appear in Phys. Rev.

Singlet VA \tilde V correlator within the instanton vacuum model

The correlator of singlet axial-vector and vector currents in the external electromagnetic field is studied within the instanton liquid model of QCD vacuum. In the chiral limit we calculate the longitudinal w_L^0 and transversal w_T^0 with respect to axial-vector index invariant amplitudes at arbitrary momentum transfer q. It is demonstrated how the anomalous longitudinal part of the correlator is renormalized at low momenta due to the presence of the U_A(1) anomaly.Comment: 9 pages, 4 figure