16 research outputs found

    The Importance of Energy Efficient in Wireless Sensor Networks

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    Mobile Node-based routing is an efficient routing technique compared to traditional approaches. Due to this FERP majorly data isolation is provided for sensor nodes, and the network is more energy efficient. The Mobile data collector collects data from only Family heads and forwards to the cluster head. The Node level energy saving scheme is proposed in this work. The performance of this routing protocol is assessed based on Energy consumption, Throughput, Lifetime, Packet Delivery Ratio, Energy efficiency. Most of the Energy is saved due to the introducing of mobile nodes for data collection. Apart from this, we are reducing the load for mobile data collectors also. In general, mobile data collectors have high energy resources. But it is not possible in all terrains. This FERP gives better results in military and plateaus, and irregular terrains where multihop communication is complex. This work is further enhanced by Trust node based routing to improve the lifetime of the network

    Metal artefacts in Chalcolithic Cyprus:New data from Western Cyprus

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    <p>The origins of copper-based metallurgy on the island of Cyprus, which became the main supplier of the metal in the Late Bronze Age in the Mediterranean and whose name became associated with the metal, is relatively obscure. While metal extraction and metal artefacts became increasingly important in the broader Near East, early metallurgy on Cyprus remains poorly known, and it is often postulated that metals were of limited importance on the island prior to the Philia phase. Here we present a unique context from the Late Chalcolithic (ca. 2800-2400 BC) from the excavations at Chlorakas- Palloures that has considerable ramifications for this debate.</p

    Outcomes of retained and disengaged pregnant women living with HIV in Uganda.

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    IntroductionLoss-to-follow-up among women living with HIV (WLWHIV) may lead to unfavorable outcomes for both mother and exposed infant. This study traced WLWHIV disengaged from care and their infants and compared their outcomes with those retained in care.MethodsThe study included WLWHIV who initiated ART during pregnancy at six public clinics in Uganda. A woman was defined as disengaged (DW) if she had not attended her 6-week post-partum visit by 10 weeks after her estimated date of delivery. DW were matched with retained women (RW) by age and duration on ART. Nurse counselors traced all selected DW via telephone and community visits to assess vital status, infant HIV sero-status and maternal HIV viral load through blood draws.ResultsBetween July 2017 and July 2018, 734 women (359 DW and 375 RW) were identified for the study. Tracing was attempted on 349 DW and 160 (44.6%) were successfully located and enrolled in the study. They were matched with 162 RW. Among DW, 52 (32.5%) transferred to another health facility. Very few DW, 39.0% were HIV virally suppressed (ConclusionPregnant and breastfeeding WLWHIV who disengage from care are difficult to find in urban environments. Many have detectable viral loads, leading to the potential for an increased risk of MTCT. Efforts to reduce disengagement from care are critical for the successful elimination of MTCT in resource-limited settings

    Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine on human cytomegalovirus replication in vitro

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    We studied the effect of a novel purine acyclic nucleoside, 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG), on human cytomegalovirus (HCMV) replication. The susceptibility of HCMV to this drug was monitored in cell culture by plaque reduction assay. HCMV replication of various strains was inhibited to the extent of 50% by 1 to 5 microM DHPG. DHPG was highly specific in its anti-HCMV activity, since at concentrations as high as 100 microM it did not exert any detectable inhibitory effect on uninfected cell macromolecular synthesis and cell growth. At concentrations of 2 to 4 microM, the drug inhibited the synthesis of six virus-specific polypeptides with molecular weights of 200,000 (VP200), 150,000 (VP150), 67,000 (VP67), 54,000 (VP54), 32,000 (VP32), and 27,000 (VP27) up to 96 h after infection. HCMV DNA synthesis was also considerably suppressed at concentrations of 2 to 4 microM DHPG. Upon removal of the inhibitor, however, viral DNA synthesis resumed and infectious virus reappeared, indicating that this inhibition was a virostatic reversible-type inhibition
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