647 research outputs found

    Dynamics of filaments and membranes in a viscous fluid

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    Motivated by the motion of biopolymers and membranes in solution, this article presents a formulation of the equations of motion for curves and surfaces in a viscous fluid. We focus on geometrical aspects and simple variational methods for calculating internal stresses and forces, and we derive the full nonlinear equations of motion. In the case of membranes, we pay particular attention to the formulation of the equations of hydrodynamics on a curved, deforming surface. The formalism is illustrated by two simple case studies: (1) the twirling instability of straight elastic rod rotating in a viscous fluid, and (2) the pearling and buckling instabilities of a tubular liposome or polymersome.Comment: 26 pages, 12 figures, to be published in Reviews of Modern Physic

    Pain management in the neonatal piglet during routine management procedures. Part 2:Grading the quality of evidence and the strength of recommendations

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    Piglets reared in swine production in the USA undergo painful procedures that include castration, tail docking, teeth clipping, and identification with ear notching or tagging. These procedures are usually performed without pain mitigation. The objective of this project was to develop recommendations for pain mitigation in 1- to 28-day-old piglets undergoing these procedures. The National Pork Board funded project to develop recommendations for pain mitigation in piglets. Recommendation development followed a defined multi-step process that included an evidence summary and estimates of the efficacies of interventions. The results of a systematic review of the interventions were reported in a companion paper. This manuscript describes the recommendation development process and the final recommendations. Recommendations were developed for three interventions (CO2/O2 general anesthesia, non-steroidal anti-inflammatory drugs (NSAIDs), and lidocaine) for use during castration. The ability to make strong recommendations was limited by low-quality evidence and strong certainty about variation in stakeholder values and preferences. The panel strongly recommended against the use of a CO2/O2 general anesthesia mixture, weakly recommended for the use of NSAIDs and weakly recommended against the use of lidocaine for pain mitigation during castration of 1- to 28-day-old piglets

    Review: Assessment of completeness of reporting in intervention studies using livestock: an example from pain mitigation interventions in neonatal piglets

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    Accurate and complete reporting of study methods, results and interpretation are essential components for any scientific process, allowing end-users to evaluate the internal and external validity of a study. When animals are used in research, excellence in reporting is expected as a matter of continued ethical acceptability of animal use in the sciences. Our primary objective was to assess completeness of reporting for a series of studies relevant to mitigation of pain in neonatal piglets undergoing routine management procedures. Our second objective was to illustrate how authors can report the items in the Reporting guidElines For randomized controLled trials for livEstoCk and food safety (REFLECT) statement using examples from the animal welfare science literature. A total of 52 studies from 40 articles were evaluated using a modified REFLECT statement. No single study reported all REFLECT checklist items. Seven studies reported specific objectives with testable hypotheses. Six studies identified primary or secondary outcomes. Randomization and blinding were considered to be partially reported in 21 and 18 studies, respectively. No studies reported the rationale for sample sizes. Several studies failed to report key design features such as units for measurement, means, standard deviations, standard errors for continuous outcomes or comparative characteristics for categorical outcomes expressed as either rates or proportions. In the discipline of animal welfare science, authors, reviewers and editors are encouraged to use available reporting guidelines to ensure that scientific methods and results are adequately described and free of misrepresentations and inaccuracies. Complete and accurate reporting increases the ability to apply the results of studies to the decision-making process and prevent wastage of financial and animal resources

    On the Study of Hyperbolic Triangles and Circles by Hyperbolic Barycentric Coordinates in Relativistic Hyperbolic Geometry

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    Barycentric coordinates are commonly used in Euclidean geometry. Following the adaptation of barycentric coordinates for use in hyperbolic geometry in recently published books on analytic hyperbolic geometry, known and novel results concerning triangles and circles in the hyperbolic geometry of Lobachevsky and Bolyai are discovered. Among the novel results are the hyperbolic counterparts of important theorems in Euclidean geometry. These are: (1) the Inscribed Gyroangle Theorem, (ii) the Gyrotangent-Gyrosecant Theorem, (iii) the Intersecting Gyrosecants Theorem, and (iv) the Intersecting Gyrochord Theorem. Here in gyrolanguage, the language of analytic hyperbolic geometry, we prefix a gyro to any term that describes a concept in Euclidean geometry and in associative algebra to mean the analogous concept in hyperbolic geometry and nonassociative algebra. Outstanding examples are {\it gyrogroups} and {\it gyrovector spaces}, and Einstein addition being both {\it gyrocommutative} and {\it gyroassociative}. The prefix "gyro" stems from "gyration", which is the mathematical abstraction of the special relativistic effect known as "Thomas precession".Comment: 78 pages, 26 figure

    The retirement experiences of elite female gymnasts: Self identity and the physical self

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    This study explored experiences of retirement from elite sport among a sample of retired female gymnasts. Given the young age at which female gymnasts begin and end their sport careers, particular attention was afforded to the role of identity and the physical self in the process of adaptation. Retrospective, semi-structured interviews were conducted and interview transcripts analyzed using interpretative phenomenological analysis. Analysis indicated that retirement from gymnastics engendered adjustment difficulties for six of the seven participants. Identity loss was particularly salient, and for two gymnasts, physical changes associated with retirement were a further source of distress. The challenge of athletic retirement was intensified because the gymnasts had heavily invested in sport during adolescence, a period demarcated for the pursuit of an identity. Furthermore, their retirement coincided with a time when adolescents typically undergo profound changes physiologically. Practical suggestions to facilitate athletes' disengagement from sport are discussed
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