Dendritic Actin Filament Nucleation Causes Traveling Waves and Patches

The polymerization of actin via branching at a cell membrane containing nucleation-promoting factors is simulated using a stochastic-growth methodology. The polymerized-actin distribution displays three types of behavior: a) traveling waves, b) moving patches, and c) random fluctuations. Increasing actin concentration causes a transition from patches to waves. The waves and patches move by a treadmilling mechanism which does not require myosin II. The effects of downregulation of key proteins on actin wave behavior are evaluated.Comment: 10 pages, 4 figure

Endpoint behavior of the pion distribution amplitude in QCD sum rules with nonlocal condensates

Starting from the QCD sum rules with nonlocal condensates for the pion distribution amplitude, we derive another sum rule for its derivative and its "integral" derivatives---defined in this work. We use this new sum rule to analyze the fine details of the pion distribution amplitude in the endpoint region $x\sim 0$. The results for endpoint-suppressed and flat-top (or flat-like) pion distribution amplitudes are compared with those we obtained with differential sum rules by employing two different models for the distribution of vacuum-quark virtualities. We determine the range of values of the derivatives of the pion distribution amplitude and show that endpoint-suppressed distribution amplitudes lie within this range, while those with endpoint enhancement---flat-type or CZ-like---yield values outside this range.Comment: 20 pages, 10 figures, 1 table, conclusions update

Gluon Field Strength Correlation Functions within a Constrained Instanton Model

We suggest a constrained instanton (CI) solution in the physical QCD vacuum which is described by large-scale vacuum field fluctuations. This solution decays exponentially at large distances. It is stable only if the interaction of the instanton with the background vacuum field is small and additional constraints are introduced. The CI solution is explicitly constructed in the ansatz form, and the two-point vacuum correlator of gluon field strengths is calculated in the framework of the effective instanton vacuum model. At small distances the results are qualitatively similar to the single instanton (SI) case, in particular, the form factor $D_{1}$ is small, which is in agreement with the lattice calculations.Comment: 25 pages (RevTex), 7 ps figures; some references added, one figure replace

Theoretical backgrounds of durability analysis by normalized equivalent stress functionals

Generalized durability diagrams and their properties are considered for a material under a multiaxial loading given by an arbitrary function of time. Material strength and durability under such loading are described in terms of durability, safety factor and normalized equivalent stress. Relations between these functionals are analysed. We discuss some material properties including time and load stability, self-degradation (ageing), and monotonic damaging. Phenomenological strength conditions are presented in terms of the normalized equivalent stress. It is shown that the damage based durability analysis is reduced to a particular case of such strength conditions. Examples of the reduction are presented for some known durability models. The approach is applicable to the strength and durability description at creep and impact loading and their combination

Numerical solution and spectrum of boundary-domain integral equation for the Neumann BVP with variable coefficient

This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2012 Taylor & Francis.In this paper, a numerical implementation of a direct united boundary-domain integral equation (BDIE) related to the Neumann boundary value problem for a scalar elliptic partial differential equation with a variable coefficient is discussed. The BDIE is reduced to a uniquely solvable one by adding an appropriate perturbation operator. The mesh-based discretization of the BDIEs with quadrilateral domain elements leads to a system of linear algebraic equations (discretized BDIE). Then, the system is solved by LU decomposition and Neumann iterations. Convergence of the iterative method is discussed in relation to the distribution of eigenvalues of the corresponding discrete operators calculated numerically.The work was supported by the grant EP/H020497/1 "Mathematical analysis of localised boundary-domain integral equations for BVPs with variable coefficients" of the EPSRC, UK

Traveling and pinned fronts in bistable reaction-diffusion systems on network

Traveling fronts and stationary localized patterns in bistable reaction-diffusion systems have been broadly studied for classical continuous media and regular lattices. Analogs of such non-equilibrium patterns are also possible in networks. Here, we consider traveling and stationary patterns in bistable one-component systems on random Erd\"os-R\'enyi, scale-free and hierarchical tree networks. As revealed through numerical simulations, traveling fronts exist in network-organized systems. They represent waves of transition from one stable state into another, spreading over the entire network. The fronts can furthermore be pinned, thus forming stationary structures. While pinning of fronts has previously been considered for chains of diffusively coupled bistable elements, the network architecture brings about significant differences. An important role is played by the degree (the number of connections) of a node. For regular trees with a fixed branching factor, the pinning conditions are analytically determined. For large Erd\"os-R\'enyi and scale-free networks, the mean-field theory for stationary patterns is constructed

Propagation failure of excitation waves on trees and random networks

Excitation waves are studied on trees and random networks of coupled active elements. Undamped propagation of such waves is observed in those networks. It represents an excursion from the resting state and a relaxation back to it for each node. However, the degrees of the nodes influence drastically the dynamics. Excitation propagates more slowly through nodes with larger degrees and beyond some critical degree waves lose their stability and disappear. For regular trees with a fixed branching ratio, the critical degree is determined with an approximate analytical theory which also holds locally for the early stage of excitation spreading in random networks.Comment: 7 pages, 7 figures, submitted to ep

History-sensitive accumulation rules for life-time prediction under variable loading

This is the post-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 SpringerA general form of temporal strength conditions under variable creep loading is employed to formulate several new phenomenological accumulation rules based on the constant-loading durability diagram. Unlike the well-known Robinson rule of linear accumulation of partial life-times, the new rules allow to describe the life-time sensibility to the load sequence, observed in experiments. Comparison of the new rules with experimental data shows that they fit the data much more accurately than the Robinson rule

Perturbative Symmetry Approach

Perturbative Symmetry Approach is formulated in symbolic representation. Easily verifiable integrability conditions of a given equation are constructed in the frame of the approach. Generalisation for the case of non-local and non-evolution equations is disscused. Application of the theory to the Benjamin-Ono and Camassa-Holm type equations is considered.Comment: 16 page