4,919 research outputs found

    Public Authorities as Defendants: Using Bayesian Networks to determine the Likelihood of Success for Negligence claims in the wake of Oakden

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    Several countries are currently investigating issues of neglect, poor quality care and abuse in the aged care sector. In most cases it is the State who license and monitor aged care providers, which frequently introduces a serious conflict of interest because the State also operate many of the facilities where our most vulnerable peoples are cared for. Where issues are raised with the standard of care being provided, the State are seen by many as a deep-pockets defendant and become the target of high-value lawsuits. This paper draws on cases and circumstances from one jurisdiction based on the English legal tradition, Australia, and proposes a Bayesian solution capable of determining probability for success for citizen plaintiffs who bring negligence claims against a public authority defendant. Use of a Bayesian network trained on case audit data shows that even when the plaintiff case meets all requirements for a successful negligence litigation, success is not often assured. Only in around one-fifth of these cases does the plaintiff succeed against a public authority as defendant

    ‘I understood the words but I didn’t know what they meant’: Japanese online MBA students’ experiences of British assessment practices

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    We report on a case study of high Japanese student failure rates in an online MBA programme. Drawing on interviews, and reviews of exam and assignment scripts we frame the problems faced by these students in terms of a ‘language as social practice’ approach and highlight the students’ failure to understand the specific language games that underpin the course assessment approach. We note the way in which the distance learning and online context can make the challenges faced by international students less immediately visible to both students and institution

    Cardiac cell modelling: Observations from the heart of the cardiac physiome project

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    In this manuscript we review the state of cardiac cell modelling in the context of international initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim to integrate computational models across scales and physics. In particular we focus on the relationship between experimental data and model parameterisation across a range of model types and cellular physiological systems. Finally, in the context of parameter identification and model reuse within the Cardiac Physiome, we suggest some future priority areas for this field

    Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk

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    Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to provisioning across both scales are rare. We tested these relationships with a 4-year study of 369 common vampire bats across 10 sites in Peru and Belize that differ in the abundance of livestock, an important anthropogenic food source. We quantified innate and adaptive immunity from bats and assessed infection with two common bacteria. We predicted that abundant livestock could reduce starvation and foraging effort, allowing for greater investments in immunity. Bats from high-livestock sites had higher microbicidal activity and proportions of neutrophils but lower immunoglobulin G and proportions of lymphocytes, suggesting more investment in innate relative to adaptive immunity and either greater chronic stress or pathogen exposure. This relationship was most pronounced in reproductive bats, which were also more common in high-livestock sites, suggesting feedbacks between demographic correlates of provisioning and immunity. Infection with both Bartonella and haemoplasmas were correlated with similar immune profiles, and both pathogens tended to be less prevalent in high-livestock sites, although effects were weaker for haemoplasmas. These differing responses to provisioning might therefore reflect distinct transmission processes. Predicting how provisioning alters host–pathogen interactions requires considering how both within-host processes and transmission modes respond to resource shifts

    A framework for the simulation of structural software evolution

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    This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 ACM.As functionality is added to an aging piece of software, its original design and structure will tend to erode. This can lead to high coupling, low cohesion and other undesirable effects associated with spaghetti architectures. The underlying forces that cause such degradation have been the subject of much research. However, progress in this field is slow, as its complexity makes it difficult to isolate the causal flows leading to these effects. This is further complicated by the difficulty of generating enough empirical data, in sufficient quantity, and attributing such data to specific points in the causal chain. This article describes a framework for simulating the structural evolution of software. A complete simulation model is built by incrementally adding modules to the framework, each of which contributes an individual evolutionary effect. These effects are then combined to form a multifaceted simulation that evolves a fictitious code base in a manner approximating real-world behavior. We describe the underlying principles and structures of our framework from a theoretical and user perspective; a validation of a simple set of evolutionary parameters is then provided and three empirical software studies generated from open-source software (OSS) are used to support claims and generated results. The research illustrates how simulation can be used to investigate a complex and under-researched area of the development cycle. It also shows the value of incorporating certain human traits into a simulation—factors that, in real-world system development, can significantly influence evolutionary structures

    Josephson Current between Triplet and Singlet Superconductors

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    The Josephson effect between triplet and singlet superconductors is studied. Josephson current can flow between triplet and singlet superconductors due to the spin-orbit coupling in the spin-triplet superconductor but it is finite only when triplet superconductor has Lz=−Sz=±1L_z=-S_z=\pm 1, where LzL_z and SzS_z are the perpendicular components of orbital angular momentum and spin angular momentum of the triplet Cooper pairs, respectively. The recently observed temperature and orientational dependence of the critical current through a Josephson junction between UPt3_3 and Nb is investigated by considering a non-unitary triplet state.Comment: 4 pages, no figure

    The Incidence of Cancer in a Population-Based Cohort of Canadian Heart Transplant Recipients

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    To assess the long-term risk of developing cancer among heart transplant recipients compared to the Canadian general population, we carried out a retrospective cohort study of 1703 patients who received a heart transplant between 1981 and 1998, identified from the Canadian Organ Replacement Register database. Vital status and cancer incidence were determined through record linkage to the Canadian Mortality Database and Canadian Cancer Registry. Cancer incidence rates among heart transplant patients were compared to those of the general population. The observed number of incident cancers was 160 with 58.9 expected in the general population (SIR = 2.7, 95% CI = 2.3, 3.2). The highest ratios were for non-Hodgkin's lymphoma (NHL) (SIR = 22.7, 95% CI = 17.3, 29.3), oral cancer (SIR = 4.3, 95% CI = 2.1, 8.0) and lung cancer (SIR = 2.0, 95% CI = 1.2, 3.0). Compared to the general population, SIRs for NHL were particularly elevated in the first year posttransplant during more recent calendar periods, and among younger patients. Within the heart transplant cohort, overall cancer risks increased with age, and the 15-year cumulative incidence of all cancers was estimated to be 17%. There is an excess of incident cases of cancer among heart transplant recipients. The relative excesses are most marked for NHL, oral and lung cancer.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79130/1/j.1600-6143.2009.02973.x.pd
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