2,545 research outputs found

    Generalized hydrodynamics of a dilute finite-sized particles suspension: Dynamic viscosity

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    We present a mesoscopic hydrodynamic description of the dynamics of colloidal suspensions. We consider the system as a gas of Brownian particles suspended in a Newtonian heat bath subjected to stationary non-equilibrium conditions imposed by a velocity field. Using results already obtained in previous studies in the field by means of a generalized Fokker-Planck equation, we obtain a set of coupled differential equations for the local diffusion current and the evolution of the total stress tensor. We find that the dynamic shear viscosity of the system contains contributions arising from the finite size of the particles.Comment: To appear in Physical Review

    Fuzzy Control Strategy for an Anaerobic Wastewater Treatment Process

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    In this paper, a fuzzy control strategy (FCS) for an anaerobic wastewater treatment process is proposed in order to reject large disturbances on input substrate allowing a high methane production. This strategy is composed of: i) a state observer, which is based on a principal components analysis (PCA) and Takagi-Sugeno (TS) algorithm; it is designed to estimate variables hard to measure: biomass and substrate, ii) proportional-integral (PI) controllers based on a combination of the L/A(logarithm/antilogarithm) and fuzzy approaches; these controllers have variable gains and are designed to regulate bicarbonate in the reactor by two control actions: a base supplying (binc) and dilution rate (D) changes, iii) a TS supervisor which detects the process state, selects and applies the most adequate control action, allowing a smooth switching between open loop and closed loop. Applicability of the proposed structure in a completely stirred tank reactor (CSTR) is illustrated via simulations. The obtained results show that the process works in open loop in presence of small disturbances. For large disturbances, the supervisor allows the control actions to be applied avoiding washout; after that, the process returns to open loop operation. In general, the FCS improves the performances of the anaerobic process and is feasible for application in real processes, since the control scheme shows a good compromise between efficiency and complexity

    The Comparability of Men Who Have Sex With Men Recruited From Venue-Time-Space Sampling and Facebook: A Cohort Study

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    Background: Recruiting valid samples of men who have sex with men (MSM) is a key component of the US human immunodeficiency virus (HIV) surveillance and of research studies seeking to improve HIV prevention for MSM. Social media, such as Facebook, may present an opportunity to reach broad samples of MSM, but the extent to which those samples are comparable with men recruited from venue-based, time-space sampling (VBTS) is unknown. Objective: The objective of this study was to assess the comparability of MSM recruited via VBTS and Facebook. Methods: HIV-negative and HIV-positive black and white MSM were recruited from June 2010 to December 2012 using VBTS and Facebook in Atlanta, GA. We compared the self-reported venue attendance, demographic characteristics, sexual and risk behaviors, history of HIV-testing, and HIV and sexually transmitted infection (STI) prevalence between Facebook- and VTBS-recruited MSM overall and by race. Multivariate logistic and negative binomial models estimated age/race adjusted ratios. The Kaplan-Meier method was used to assess 24-month retention. Results: We recruited 803 MSM, of whom 110 (34/110, 30.9% black MSM, 76/110, 69.1% white MSM) were recruited via Facebook and 693 (420/693, 60.6% black MSM, 273/693, 39.4% white MSM) were recruited through VTBS. Facebook recruits had high rates of venue attendance in the previous month (26/34, 77% among black and 71/76, 93% among white MSM; between-race P=.01). MSM recruited on Facebook were generally older, with significant age differences among black MSM (P=.02), but not white MSM (P=.14). 
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    Dopamine D 4 Receptor-Deficient Mice Display Cortical Hyperexcitability

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    The dopamine D(4) receptor (D(4)R) is predominantly expressed in the frontal cortex (FC), a brain region that receives dense input from midbrain dopamine (DA) neurons and is associated with cognitive and emotional processes. However, the physiological significance of this dopamine receptor subtype has been difficult to explore because of the slow development of D(4)R agonists and antagonists the selectivity and efficacy of which have been rigorously demonstrated in vivo. We have attempted to overcome this limitation by taking a multidimensional approach to the characterization of mice completely deficient in this receptor subtype. Electrophysiological current and voltage-clamp recordings were performed in cortical pyramidal neurons from wild-type and D(4)R-deficient mice. The frequency of spontaneous synaptic activity and the frequency and duration of paroxysmal discharges induced by epileptogenic agents were increased in mutant mice. Enhanced synaptic activity was also observed in brain slices of wild-type mice incubated in the presence of the selective D(4)R antagonist PNU-101387G. Consistent with greater electrophysiological activity, nerve terminal glutamate density associated with asymmetrical synaptic contacts within layer VI of the motor cortex was reduced in mutant neurons. Taken together, these results suggest that the D(4)R can function as an inhibitory modulator of glutamate activity in the FC.Fil: Rubinstein, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Cepeda, Carlos. University of California at Los Angeles; Estados UnidosFil: Hurst, Raymond S.. University of California at Los Angeles; Estados UnidosFil: Flores Hernandez, Jorge. University of California at Los Angeles; Estados UnidosFil: Ariano, Marjorie A.. The Chicago Medical School; Estados UnidosFil: Falzone, Tomas Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; ArgentinaFil: Kozell, Laura B.. Oregon Health Sciences University; Estados UnidosFil: Meshul, Charles K.. Oregon Health Sciences University; Estados UnidosFil: Bunzow, James R.. Oregon Health Sciences University; Estados UnidosFil: Low, Malcolm J.. Oregon Health Sciences University; Estados UnidosFil: Levine, Michael S.. University of California at Los Angeles; Estados UnidosFil: Grandy, David K.. Oregon Health Sciences University; Estados Unido

    Gendered opportunities for improving soil health: A conceptual framework to help set the research agenda

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    Healthy soils play a critical role in supporting agricultural productivity, climate change mitigation and resilience, and a range of ecosystem services. Degraded and poorly responsive soils cover large areas of Africa and represent the majority of poor farmers’ fields in certain regions. While there are hundreds of technical options for improving the sustainability of land management and preventing or reversing degradation, there are many sociocultural, institutional, economic, and policy barriers hindering their adoption at large scale. At the same time, there is an emerging consensus within the international development community that gender equality and women’s empowerment are both an end in themselves and an important means for achieving a range of economic and social development objectives such as improved food security, child nutrition and education, and women’s health. Yet, gender inequality remains a wicked problem, whose deep-seated socio-economic and ideological causes are difficult to recognize and address, and which require context- and culture-specific understandings and approaches, involving multiple stakeholders with different and sometimes conflicting interests and different positions within power hierarchies. There is an urgent need to make more rapid progress on restoring and sustaining soil productivity and ecosystem functions and also to leverage soil health management for progress on gender equality. While there are important interconnections between soil health and gender equality and empowerment, these are seldom recognized, and have not been addressed in a coherent or concerted manner. In this study, we have reviewed relevant gender literature and proposed a conceptual framework to help illuminate important gender considerations for soil health and land management. These considerations are essential for identifying gender-based constraints, opportunities, and unintended consequences in promoting soil management technologies. Moreover, the application of the framework can help guide in priority setting with respect to where gender-responsive interventions are essential. We make several recommendations for setting priorities for gender-soil health research

    Cardiopulmonary Mortality and Fine Particulate Air Pollution by Species and Source in a National U.S. Cohort

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    The purpose of this study was to estimate cardiopulmonary mortality associations for long-term exposure to PM2.5 species and sources (i.e., components) within the U.S. National Health Interview Survey cohort. Exposures were estimated through a chemical transport model for six species (i.e., elemental carbon (EC), primary organic aerosols (POA), secondary organic aerosols (SOA), sulfate (SO4), ammonium (NH4), nitrate (NO3)) and five sources of PM2.5 (i.e., vehicles, electricity-generating units (EGU), non-EGU industrial sources, biogenic sources (bio), “other” sources). In single-pollutant models, we found positive, significant (p < 0.05) mortality associations for all components, except POA. After adjusting for remaining PM2.5 (total PM2.5 minus component), we found significant mortality associations for EC (hazard ratio (HR) = 1.36; 95% CI [1.12, 1.64]), SOA (HR = 1.11; 95% CI [1.05, 1.17]), and vehicle sources (HR = 1.06; 95% CI [1.03, 1.10]). HRs for EC, SOA, and vehicle sources were significantly larger in comparison to those for remaining PM2.5 (per unit ÎŒg/m3). Our findings suggest that cardiopulmonary mortality associations vary by species and source, with evidence that EC, SOA, and vehicle sources are important contributors to the PM2.5 mortality relationship. With further validation, these findings could facilitate targeted pollution regulations that more efficiently reduce air pollution mortality.This publication was developed as part of the Center for Air, Climate, and Energy Solutions (CACES), which was supported under Assistance Agreement No. R835873 awarded by the U.S. Environmental Protection Agency. It has not been formally reviewed by EPA. The views expressed in this document are solely those of authors and do not necessarily reflect those of the Agency. EPA does not endorse any products or commercial services mentioned in this publication. We also acknowledge support from the European Union’s Horizon 2020 Research and Innovation project REMEDIA under grant agreement No 874753.Peer Reviewed"Article signat per 13 autors/es:" Zachari A. Pond, Carlos S. Hernandez, Peter J. Adams, Spyros N. Pandis, George R. Garcia, Allen L. Robinson, Julian D. Marshall, Richard Burnett, Ksakousti Skyllakou, Pablo Garcia Rivera, Eleni Karnezi, Carver J. Coleman, C. Arden Pope III"Postprint (author's final draft

    the SDSS-III APOGEE Spectral Line List for H-Band Spectroscopy

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    We present the H-band spectral line lists adopted by the Apache Point Observatory Galactic Evolution Experiment (APOGEE). The APOGEE line lists comprise astrophysical, theoretical, and laboratory sources from the literature, as well as newly evaluated astrophysical oscillator strengths and damping parameters. We discuss the construction of the APOGEE line list, which is one of the critical inputs for the APOGEE Stellar Parameters and Chemical Abundances Pipeline, and present three different versions that have been used at various stages of the project. The methodology for the newly calculated astrophysical line lists is reviewed. The largest of these three line lists contains 134,457 molecular and atomic transitions. In addition to the format adopted to store the data, the line lists are available in MOOG, Synspec, and Turbospectrum formats. The limitations of the line lists along with guidance for its use on different spectral types are discussed. We also present a list of H-band spectral features that are either poorly represented or completely missing in our line list. This list is based on the average of a large number of spectral fit residuals for APOGEE observations spanning a wide range of stellar parameters.Alfred P. Sloan FoundationNational Science FoundationU.S. Department of Energy Office of ScienceJanos Bolyai Research Scholarship of the Hungarian Academy of SciencesSpanish Ministry of Economy and Competitiveness AYA-2011-27754, AYA-2014-58082-PRSF 14-50-00043McDonald Observator

    Hybrid Intelligent Inverse Optimal Control forMethane Production in an Anaerobic Process

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    Anaerobic processes are very attractive because of their waste treatment properties and their capacity for transforming waste materials in order to generate methane, which can be used as a renewable energy source. A hybrid intelligent control strategy for an anaerobic process is proposed in this work; the structure of this strategy is as follows: a) a control law calculates dilution rate and bicarbonate addition in order to track a methaneproduction reference trajectory; this control law is based on speed-gradient inverse optimalneural control, b) a nonlinear discrete-time recurrent high-order neural observer isused to estimate biomass concentration, substrate degradation and inorganic carbon, and c) a Takagi-Sugeno supervisor, which detects the process state, selects and applies themost adequate control action, allowing a smooth switching between open loop and closed loop. The applicability of the proposed scheme is illustrated via simulations consideringa completely stirred tank reactor

    A Study of the Near-Ultraviolet Spectrum of Vega

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    UV, optical, and near-IR spectra of Vega have been combined to test our understanding of stellar atmospheric opacities, and to examine the possibility of constraining chemical abundances from low-resolution UV fluxes. We have carried out a detailed analysis assuming Local Thermodynamic Equilibrium (LTE) to identify the most important contributors to the UV continuous opacity: H, H−^{-}, C I, and Si II. Our analysis also assumes that Vega is spherically symmetric and its atmosphere is well described with the plane parallel approximation. Comparing observations and computed fluxes we have been able to discriminate between two different flux scales that have been proposed, the IUE-INES and the HST scales, favoring the latter. The effective temperature and angular diameter derived from the analysis of observed optical and near-UV spectra are in very good agreement with previous determinations based on different techniques. The silicon abundance is poorly constrained by the UV observations of the continuum and strong lines, but the situation is more favorable for carbon and the abundances inferred from the UV continuum and optical absorption lines are in good agreement. Some spectral intervals in the UV spectrum of Vega that the calculations do not reproduce well are likely affected by deviations from LTE, but we conclude that our understanding of UV atmospheric opacities is fairly complete for early A-type stars.Comment: 13 pages, 9 figures, to be published in Ap
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