763 research outputs found

    Misplaced expectations from climate disclosure initiatives

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    The financial sector’s response to pressures around climate change has emphasized the role of disclosure, notably through the recommendations of the Financial Stability Board’s Task Force on Climate-related Financial Disclosures. This Perspective examines two dimensions of the expectations behind transparency and disclosure initiatives: the belief that disinvestment is driven by disclosure; and that investment ‘switches’ from high- to low-carbon assets. We warn about the risk of disappointment from inflated expectations about what transparency can really deliver and suggest some areas that research and public policy should examine to mobilize the required capital to meet climate goals

    Performance Results of a Prototype Board Designed for Copper Data Transmission in KM3NeT

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    International audienceThe experience gained in designing submarine neutrino telescopes suggested to explore new ways of realizing the data transmission backbone at the detection unit level. In order to decrease the difficulties of integration and handling of the backbones, some effort has been spent in developing a backbone based on copper links with simple tracts of cable connecting contiguous storeys. This work is aimed at the presentation of the general architecture of the system, at the description of an electronic board prototype designed to test the project feasibility with the first results obtained. The main goal of the experimental setup was measuring the recovered clock jitter under various conditions, with and without cables. The jitter measured on the cleaned clock amounts to hundreds of picoseconds, well below the sub-nanosecond time resolution required by this kind of experiments

    Investment suitability and path dependency perpetuate inequity in international mitigation finance toward developing countries

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    Developed country pledges to provide finance to developing countries for their mitigation actions sit at the heart of international climate cooperation. Currently, climate finance largely flows to big and fast-growing developing countries while low-income and vulnerable countries are underserved. Here, using wind and solar project data, we highlight inequities in the distribution of international investments in mitigation across developing countries and explore the factors that influence public and private investment flows. Results show that public actors are influenced by domestic climate policies since the Paris Agreement, while private finance flows are shaped by investment suitability conditions, which restricts access to both types of finance in the poorest countries. Further, public and private flows are strongly shaped by path dependency, generating an “investment lock-in” that perpetuates distributional inequities. Future international commitments to direct climate finance should address distributional issues to meet countries’ needs and the goals of the Paris Agreement

    The role of inhalational anesthetic drugs in patients with hepatic dysfunction: A review article

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    Context: Anesthetic drugs including halogenated anesthetics have been common for many years. Consequent hepatic injury has been reported in the literature. The mechanism of injury is immunoallergic. The first generation drug was halothane; it had the most toxicity when compared to other drugs. The issue becomes more important when the patient has an underlying hepatic dysfunction. Evidence Acquisition: In this paper, reputable internet databases from 1957�2014 were analyzed and 43 original articles, 3 case reports, and 3 books were studied. A search was performed based on the following keywords: inhalational anesthesia, hepatic dysfunction, halogenated anesthetics, general anesthesia in patients with hepatic diseases, and side effects of halogenated anesthetics from reliable databases. Reputable websites like PubMed and Cochrane were used for the searches. Results: In patients with hepatic dysfunction in addition to hepatic system and dramatic hemostatic dysfunction, dysfunction of cardiovascular, renal, respiratory, gastrointestinal, and central nervous systems may occur. On the other hand, exposure to inhalational halogenated anesthetics may have a negative impact (similar to hepatitis) on all aforementioned systems in addition to direct effects on liver function as well as the effects are more pronounced in halothane. Conclusions: Despite the adverse effects of inhalational halogenated anesthetics (especially halothane) on hepatic patients when necessary. The effects on all systems must be considered and the necessary preparations must be provided. These drugs are still used, if necessary, due to the presence of positive effects and advantages mentioned in other studies as well as the adverse effects of other drugs. © 2015, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM)

    Delineation of Traffic Analysis Zone for Public Transportation OD Matrix Estimation Based on Socio-spatial Practices

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    This paper aims to develop and validate an efficient method for delineation of public transit analysis zones (PTTAZ), particularly for origin-destination (OD) matrix prediction for transit operation planning. Existing methods have a problem in reflecting the level of spatial precision, travel characteristics, travel demand growth, access to transit stations, and most importantly, the direction of transit routes. This study proposes a new methodology to redelineate existing traffic analysis zones (TAZ) to create PTTAZ in order to allocate travel demand to transit stops. We aim to achieve an accurate prediction of the OD matrix for public transportation (PT). The matrix should reflect the passenger accessibility in the socioeconomic and socio-spatial characterization of PTTAZ and minimize intrazonal trips. The proposed methodology transforms TAZ-based to PTTAZ-based data with sequential steps through multiple statistical methods. In short, the generation of PTTAZ establishes homogeneous sub-zones representing the relationship between passenger flow, network structure, land use, population, socio-economic characteristics, and, most importantly, existing bus transit infrastructure. To validate the proposed scheme, we implement the framework for India’s Vishakhapatnam bus network and compare the results with the household survey. The results show that the PTTAZ-based OD matrix represents a realistic scenario for PT demand

    Coronary slow flow: Benign or ominous?

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    Objective: Coronary slow flow phenomenon has been arbitrarily defined as delayed coronary blood flow in the absence of obstructive coronary artery disease. The present study sought to investigate the clinical features, natural history, and outcomes of affected patients. Methods: In this prospective cross-sectional study, 217 consecutive patients who had undergone coronary angiography and showed features of coronary slow flow phenomenon were evaluated for demographic and coronary risk factor profile, as well as clinical outcomes, at baseline and following treatment. Results: The study population consisted of 165 (76) males and 52 (24) females. The mean age of patients was 52.6±10 years. Mean ejection fraction was 48.2±5.4, 39.3 had diabetes, 43.3 had hypertension, 49.8 was a cigarette smoker, 41.9 had dyslipidemia, and 15 had a familial history of cardiac disease. Forty-nine percent was detected to have abnormal hsCRP levels. The most prevalent presenting complaint was atypical chest pain. Fifty-four percent of patients had slow blood flow in all three vessels. Thirty-six people had undergone repeat coronary angiography in a follow-up period of 5-7 years due to persisting or worsening clinical symptoms, of whom 6 (16.6) showed significant coronary artery stenosis. Eight (22.2) had mild CAD, and the rest still showed coronary slow flow without significant stenosis. The most common complaint during follow-up and after initiation of medical therapy was nonanginal chest pain. Conclusion: Patients with coronary slow flow phenomenon are predisposed to atherosclerosis and obstructive coronary artery disease. Therefore, this pathology should not be considered as a totally benign condition. Primary and secondary cardiovasculature preventive measures should be constituted and seem worthwhile in this patient population. © Copyright 2015 by Turkish Society of Cardiology

    Frequency and Predictors of Courses Repetition, Probation, and Delayed Graduation in Kashan Faculty of Nursing and Midwifery

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    Background: Course failing and delayed graduation are important concerns in educational systems. The reasons of these educational failures need to be clarified. Objectives: This study was designed to determine the academic failure rate and its predictors in Nursing and Midwifery Students in Kashan University of Medical Sciences. Materials and Methods: In this cross-sectional study, the records of all the students graduated in Nursing and Midwifery faculty during 18 years (1986 - 2003) were evaluated (1174 graduates). The demographic variables and the educational situation were recorded. The frequency of course repetition, probation, and delayed graduation were determined and the data were analyzed using the chi-square and logistic regression tests. Results: The frequency of course repetition, probation, and delayed graduation was reported to be 19.25%, 3.9% and 19.85%, respectively. Gaining Low grade in high school, transferring from other universities, having special quota, and transferring temporarily to other universities were mentioned as the risk factors of academic failure. The major had a significant relationship with academic failure. Day time students had more course failure and night time students stayed longer in the university. Conclusions: The individual characteristics, educational background and admission criteria had showed relation with academic failure. Vulnerable students should be identified and educational supports should be provided for these students

    Expectations for the high-energy neutrino detection from starburst galaxies with KM3NeT/ARCA

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    Star-forming galaxies (SFGs) and starburst galaxies (SBGs) are extragalactic sources which could produce high-energy neutrinos. In principle, they could play a rather important role for explaining at least a sizeable part of IceCube’s observations of astophysical neutrino. Using a recent theoretical model which implemented a blending of spectral indeces, we present the KM3NeT/ARCA sensitivities for such a diffuse flux from the startburst galaxies. In particular, we provide the 5-year differential sensitivity for the two building blocks of ARCA. We make use only of the track-like events in the range of 100 GeV - 10 PeV differentiate in 11 bins of energy. We show how the upcoming neutrino telescope could observe the diffuse SFG and SBG within 5 years of data taking. We found the minimum of the sensitivity at around 100 TeV, which is also the energy where the SBG contribution is expected to peak. This would not only constrain the multi-component fit of the observed astrophysical neutrino flux at that energy (100 TeV), but would also provide us a direct link between the star-forming activity in the reservoir environments and the hadronic emissions.Postprint (published version

    Development of an acoustic transceiver for the KM3NeT positioning system

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    [EN] In this paper we describe an acoustic transceiver developed for the KM3NeT positioning system. The acoustic transceiver is composed of a commercial free flooded transducer, which works mainly in the 20-40 kHz frequency range and withstands high pressures (up to 500 bars). A sound emission board was developed that is adapted to the characteristics of the transducer and meets all requirements: low power consumption, high intensity of emission, low intrinsic noise, arbitrary signals for emission and the capacity of acquiring the receiving signals with very good timing precision. The results of the different tests made with the transceiver in the laboratory and shallow sea water are described, as well as, the activities for its integration in the Instrumentation Line of the ANTARES neutrino telescope and in a NEMO tower for the in situ tests. © 2012 Elsevier B.V. All rights reserved.This work has been supported by the Ministerio de Ciencia e Innovacion (Spanish Government), Project references FPA2009-13983-C02-02, ACI2009-1067, AIC10-D-00583, and Consolider-Ingenio Multidark (CSD2009-00064). It has also been funded by Generalitat Valenciana, Prometeo/2009/26, and the European 7th Framework Programme, Grant no. 212525.Larosa, G.; Ardid Ramírez, M.; Llorens Alvarez, CD.; Bou Cabo, M.; Martínez Mora, JA.; Adrián Martínez, S.; KM3NeT Consortium (2013). Development of an acoustic transceiver for the KM3NeT positioning system. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 725:215-218. https://doi.org/10.1016/j.nima.2012.11.167S21521872
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