8,301 research outputs found
Adolescent Health Services: Missing Opportunities
Examines the status of adolescents' health and health services, including critical needs, promising models, and components for improving disease prevention and health promotion. Recommends better primary care, coordinated policy, and expanded coverage
Multiparticle Interference, GHZ Entanglement, and Full Counting Statistics
We investigate the quantum transport in a generalized N-particle Hanbury
Brown--Twiss setup enclosing magnetic flux, and demonstrate that the Nth-order
cumulant of current cross correlations exhibits Aharonov-Bohm oscillations,
while there is no such oscillation in all the lower-order cumulants. The
multiparticle interference results from the orbital Greenberger-Horne-Zeilinger
entanglement of N indistinguishable particles. For sufficiently strong
Aharonov-Bohm oscillations the generalized Bell inequalities may be violated,
proving the N-particle quantum nonlocality.Comment: 4 pages, 1 figure, published versio
Construction of optimal witness for unknown two-qubit entanglement
Whether entanglement in a state can be detected, distilled, and quantified
without full state reconstruction is a fundamental open problem. We demonstrate
a new scheme encompassing these three tasks for arbitrary two-qubit
entanglement, by constructing the optimal entanglement witness for
polarization-entangled mixed-state photon pairs without full state
reconstruction. With better efficiency than quantum state tomography, the
entanglement is maximally distilled by newly developed tunable polarization
filters, and quantified by the expectation value of the witness, which equals
the concurrence. This scheme is extendible to multiqubit
Greenberger-Horne-Zeilinger entanglement.Comment: Phys. Rev. Lett. 105, 230404 (2010); supplementary information
(OWitness_sup.pdf) is included in source zip fil
The reverberation signatures of rotating disc winds in active galactic nuclei
The broad emission lines (BELs) in active galactic nuclei (AGN) respond to
ionizing continuum variations. The time and velocity dependence of their
response depends on the structure of the broad-line region: its geometry,
kinematics and ionization state. Here, we predict the reverberation signatures
of BELs formed in rotating accretion disc winds. We use a Monte Carlo radiative
transfer and ionization code to predict velocity-delay maps for representative
high- (C) and low-ionization (H) emission lines in both high- and
moderate-luminosity AGN. Self-shielding, multiple scattering and the ionization
structure of the outflows are all self-consistently taken into account, while
small-scale structure in the outflow is modelled in the micro-clumping
approximation. Our main findings are: (1) The velocity-delay maps of
smooth/micro-clumped outflows often contain significant negative responses.
(2)~The reverberation signatures of disc wind models tend to be rotation
dominated and can even resemble the classic "red-leads-blue" inflow signature.
(3) Traditional "blue-leads-red" outflow signatures can usually only be
observed in the long-delay limit. (4) Our models predict lag-luminosity
relationships similar to those inferred from observations, but systematically
underpredict the observed centroid delays. (5) The ratio between "virial
product" and black hole mass predicted by our models depends on viewing angle.
Our results imply that considerable care needs to be taken in interpreting data
obtained by observational reverberation mapping campaigns. In particular, basic
signatures such as "red-leads-blue", "blue-leads-red" and "blue and red vary
jointly" are not always reliable indicators of inflow, outflow or rotation.
This may help to explain the perplexing diversity of such signatures seen in
observational campaigns to date.Comment: 15 pages, 17 figures, 2 tables. Accepted by MNRAS 20/7/201
Type Ia Supernovae and Accretion Induced Collapse
Using the population synthesis binary evolution code StarTrack, we present
theoretical rates and delay times of Type Ia supernovae arising from various
formation channels. These channels include binaries in which the exploding
white dwarf reaches the Chandrasekhar mass limit (DDS, SDS, and helium-rich
donor scenario) as well as the sub-Chandrasekhar mass scenario, in which a
white dwarf accretes from a helium-rich companion and explodes as a SN Ia
before reaching the Chandrasekhar mass limit. We find that using a common
envelope parameterization employing energy balance with alpha=1 and lambda=1,
the supernova rates per unit mass (born in stars) of sub-Chandrasekhar mass SNe
Ia exceed those of all other progenitor channels at epochs t=0.7 - 4 Gyr for a
burst of star formation at t=0. Additionally, the delay time distribution of
the sub-Chandrasekhar model can be divided in to two distinct evolutionary
channels: the `prompt' helium-star channel with delay times < 500 Myr, and the
`delayed' double white dwarf channel with delay times > 800 Myr spanning up to
a Hubble time. These findings are in agreement with recent
observationally-derived delay time distributions which predict that a large
number of SNe Ia have delay times < 1 Gyr, with a significant fraction having
delay times < 500 Myr. We find that the DDS channel is also able to account for
the observed rates of SNe Ia. However, detailed simulations of white dwarf
mergers have shown that most of these mergers will not lead to SNe Ia but
rather to the formation of a neutron star via accretion-induced collapse. If
this is true, our standard population synthesis model predicts that the only
progenitor channel which can account for the rates of SNe Ia is the
sub-Chandrasekhar mass scenario, and none of the other progenitors considered
can fully account for the observed rates.Comment: 6 pages, 1 figure, 1 table, to appear in proceedings for "Binary Star
Evolution: Mass Loss, Accretion and Mergers
Constraints on explosive silicon burning in core-collapse supernovae from measured Ni/Fe ratios
Measurements of explosive nucleosynthesis yields in core-collapse supernovae
provide tests for explosion models. We investigate constraints on explosive
conditions derivable from measured amounts of nickel and iron after radioactive
decays using nucleosynthesis networks with parameterized thermodynamic
trajectories. The Ni/Fe ratio is for most regimes dominated by the production
ratio of 58Ni/(54Fe + 56Ni), which tends to grow with higher neutron excess and
with higher entropy. For SN 2012ec, a supernova that produced a Ni/Fe ratio of
times solar, we find that burning of a fuel with neutron excess
is required. Unless the progenitor metallicity
is over 5 times solar, the only layer in the progenitor with such a neutron
excess is the silicon shell. Supernovae producing large amounts of stable
nickel thus suggest that this deep-lying layer can be, at least partially,
ejected in the explosion. We find that common spherically symmetric models of
Msun stars exploding with a delay time of less than
one second ( Msun) are able to achieve such silicon-shell
ejection. Supernovae that produce solar or sub-solar Ni/Fe ratios, such as SN
1987A, must instead have burnt and ejected only oxygen-shell material, which
allows a lower limit to the mass cut to be set. Finally, we find that the
extreme Ni/Fe value of 60-75 times solar derived for the Crab cannot be
reproduced by any realistic-entropy burning outside the iron core, and
neutrino-neutronization obtained in electron-capture models remains the only
viable explanation.Comment: 13 pages, 9 figures, accepted for publication in Ap
B cells are capable of independently eliciting rapid reactivation of encephalitogenic CD4 T cells in a murine model of multiple sclerosis
<div><p>Recent success with B cell depletion therapies has revitalized efforts to understand the pathogenic role of B cells in Multiple Sclerosis (MS). Using the adoptive transfer system of experimental autoimmune encephalomyelitis (EAE), a murine model of MS, we have previously shown that mice in which B cells are the only MHCII-expressing antigen presenting cell (APC) are susceptible to EAE. However, a reproducible delay in the day of onset of disease driven by exclusive B cell antigen presentation suggests that B cells require optimal conditions to function as APCs in EAE. In this study, we utilize an <i>in vivo</i> genetic system to conditionally and temporally regulate expression of MHCII to test the hypothesis that B cell APCs mediate attenuated and delayed neuroinflammatory T cell responses during EAE. Remarkably, induction of MHCII on B cells following the transfer of encephalitogenic CD4 T cells induced a rapid and robust form of EAE, while no change in the time to disease onset occurred for recipient mice in which MHCII is induced on a normal complement of APC subsets. Changes in CD4 T cell activation over time did not account for more rapid onset of EAE symptoms in this new B cell-mediated EAE model. Our system represents a novel model to study how the timing of pathogenic cognate interactions between lymphocytes facilitates the development of autoimmune attacks within the CNS.</p></div
Postfledging Survival, Movements, and Dispersal of Ring Ouzels (Turdus torquatus)
We thank Invercauld Estate for cooperation with access to Glen Clunie. S. Redpath, J. Wilson, and S. Roos provided valuable comments on the manuscript. This study was funded by the Royal Society for the Protection of Birds, Scottish Natural Heritage, and the Cairngorms National Park Authority. J.L.L. was supported by the Natural Environment Research Council.Peer reviewedPublisher PD
Deflagrations in hybrid CONe white dwarfs: a route to explain the faint Type Iax supernova 2008ha
Stellar evolution models predict the existence of hybrid white dwarfs (WDs)
with a carbon-oxygen core surrounded by an oxygen-neon mantle. Being born with
masses ~1.1 Msun, hybrid WDs in a binary system may easily approach the
Chandrasekhar mass (MCh) by accretion and give rise to a thermonuclear
explosion. Here, we investigate an off-centre deflagration in a near-MCh hybrid
WD under the assumption that nuclear burning only occurs in carbon-rich
material. Performing hydrodynamics simulations of the explosion and detailed
nucleosynthesis post-processing calculations, we find that only 0.014 Msun of
material is ejected while the remainder of the mass stays bound. The ejecta
consist predominantly of iron-group elements, O, C, Si and S. We also calculate
synthetic observables for our model and find reasonable agreement with the
faint Type Iax SN 2008ha. This shows for the first time that deflagrations in
near-MCh WDs can in principle explain the observed diversity of Type Iax
supernovae. Leaving behind a near-MCh bound remnant opens the possibility for
recurrent explosions or a subsequent accretion-induced collapse in faint Type
Iax SNe, if further accretion episodes occur. From binary population synthesis
calculations, we find the rate of hybrid WDs approaching MCh to be on the order
of 1 percent of the Galactic SN Ia rate.Comment: 9 pages, 7 figures, 2 tables, accepted for publication in MNRA
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