Volume integrals associated with the inhomegeneous Helmholtz equation. Part 2: Cylindrical region; rectangular region

Results are presented for volume integrals associated with the Helmholtz operator, nabla(2) + alpha(2), for the cases of a finite cylindrical region and a region of rectangular parallelepiped. By using appropriate Taylor series expansions and multinomial theorem, these volume integrals are obtained in series form for regions r r' and r 4', where r and r' are distances from the origin to the point of observation and source, respectively. When the wave number approaches zero, the results reduce directly to the potentials of variable densities

Performance of bolted steel-beam to CFST-column joints using stiffened angles in column-removal scenario

This paper presents three experimental investigations on the performance of steel-beam to CFST-column joints using stiffened angle, long bolts and fin plate under a middle column removal scenario. Three specimens were designed and tested. The failure modes and catenary action are investigated in detail. The test results show that increasing the angle plate thickness at the joint could not only improve its performance significantly, but also trigger an early formation of catenary action. Increasing the length of short-limb had influence on the deformation ability of the proposed joint, rather than the load capacity. The buckling of stiffeners could prevent the brittle failure of the joints. With the contribution of catenary action, the joint shows much higher rotation capacities than that required in DoD design guidance. The initial stiffness of the joint was calculated using an analytical model with consideration of bolt pretension. Good agreement to the test results is achieved. A numerical analysis is also carried out, whose results show that adding additional row of bolts would improve the redundancy of the joint under column loss. An equivalent dynamic response evaluation of the joints was also performed. The results show that dynamic amplification coefficient should be worked out considering catenary action under large deformation

Comparison between the Torquato-Rintoul theory of the interface effect in composite media and elementary results

We show that the interface effect on the properties of composite media recently proposed by Torquato and Rintoul (TR) [Phys. Rev. Lett. 75, 4067 (1995)] is in fact elementary, and follows directly from taking the limit in the dipolar polarizability of a coated sphere: the TR ``critical values'' are simply those that make the dipolar polarizability vanish. Furthermore, the new bounds developed by TR either coincide with the Clausius-Mossotti (CM) relation or provide poor estimates. Finally, we show that the new bounds of TR do not agree particularly well with the original experimental data that they quote.Comment: 13 pages, Revtex, 8 Postscript figure

Experimental and Numerical Investigation on Progressive Collapse Resistance of Post-tensioned Precast Concrete Beam-Column Sub-assemblages

In this paper, four 1/2 scaled precast concrete (PC) beam-column sub-assemblages with high performance connection were tested under push-down loading procedure to study the load resisting mechanism of PC frames subjected to different column removal scenarios. The parameters investigated include the location of column removal and effective prestress in tendons. The test results indicated that the failure modes of unbonded post-tensioned precast concrete (PTPC) frames were different from that of reinforced concrete (RC) frames: no cracks formed in the beams and wide opening formed near the beam to column interfaces. For specimens without overhanging beams, the failure of side column was eccentric compression failure. Moreover, the load resisting mechanisms in PC frames were significantly different from that of RC frames: the compressive arch action (CAA) developed in concrete during column removal was mainly due to actively applied pre-compressive stress in the concrete; CAA will not vanish when severe crush in concrete occurred. Thus, it may provide negative contribution for load resistance when the displacement exceeds one-beam depth; the tensile force developed in the tendons could provide catenary action from the beginning of the test. Moreover, to deeper understand the behavior of tested specimens, numerical analyses were carried out. The effects of concrete strength, axial compression ratio at side columns, and loading approaches on the behavior of the sub-assemblages were also investigated based on validated numerical analysis

The first operation and results of the Chung-Li VHF radar

The Chung-Li Very High Frequency (VHF) radar is used in the dual-mode operations, applying Doppler beam-swinging as well as the spaced-antenna-drift method. The design of the VHF radar is examined. Results of performance tests are discussed

3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival

Copyright © 2011 Association for Research in Vision and Ophthalmology. This article is available open access through the publisher’s website at the link below.Purpose. IDO (indoleamine 2,3-dioxygenase) modulates the immune response by depletion of the essential amino acid tryptophan, and IDO overexpression has been shown to prolong corneal allograft survival. This study was conducted to examine the effect of kynurenines, the products of tryptophan breakdown and known to act directly on T lymphocytes, on corneal graft survival. Methods. The effects of kynurenines on T-cell proliferation and death, T-regulatory-cell development, and dendritic cell function, phenotype, and viability were analyzed in vitro. The effect of topical and systemic administration of 3-hydroxykynurenine (3HK) on orthotopic murine corneal allograft survival was examined. Results. T-lymphocyte proliferation was inhibited by two of the four different kynurenines: 3HK and 3-hydroxyanthranilic acid (3HAA). This effect was accompanied by significant T-cell death. Neither 3HK nor 3HAA altered dendritic cell function, nor did they induce apoptosis or pathogenicity to corneal endothelial cells. Administration of systemic and topical 3HK to mice receiving a fully mismatched corneal graft resulted in significant prolongation of graft survival (median survival of control grafts, 12 days; of treated, 19 and 15 days, respectively; P < 0.0003). While systemic administration of 3HK was associated with a significant depletion of CD4+ T, CD8+ T, and B lymphocytes in peripheral blood, no depletion was found after topical administration. Conclusions. The production of kynurenines, in particular 3HK and 3HAA, may be one mechanism (in addition to tryptophan depletion) by which IDO prolongs graft survival. These molecules have potential as specific agents for preventing allograft rejection in patients at high rejection risk.Fight for Sight and the Wellcome Trust