122 research outputs found
Pembuatan Program Interface Untuk Pengontrolan Rv-m1
Article explores the making of interface of RV-M1 hand robot control that replaced the cosiprog program,a program that is able to help student in Mecatronica-1 Practice, and able to control the hand robot by localnetwork by two user or more. The used methods were literature study, and field study, that is design method. Theresearch result are control of hand robot on X,Y,Z axis and point to point, the use of local network to control thehand robot, save certain position, and use several user to control the robot
Atividade potencialmente alelopática em extratos aquosos de sementes e parte aérea de Pueraria phaseoloides.
Resumo também publicado em: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 37., 2000, Viçosa, MG. Resumos dos trabalhos apresentados. Viçosa, MG: Sociedade Brasileira de Zootecnia, 2000. p. 25
Terpaan Pemberitaan Media Massa dan Tingkat Kepercayaan Masyarakat pada Kompetensi Jokowi sebagai Pemimpin terhadap Minat Masyarakat Memilih Jokowi sebagai Capres
Pemberitaan mengenai Joko Widodo seringkali menjadi headline pada media massa nasional, baik media cetak, online dan televisi. Pemberitaan menjadi semakin bervariatif ketika secara resmi Joko Widodo dicalonkan sebagai capres pada pemilu 2014 yang diusung oleh partai PDI-P. Tidak hanya sejumlah keberhasilan yang dicapai selama menjadi pemimpin, namun sejumlah isu seperti konsistensi, korupsi hingga SARA terkait Jokowi mulai diangkat dan dikritisi oleh banyak pihak. Penelitian ini merupakan penelitian kuantitatif dengan tipe eksplanatori, yang bertujuan untuk mengetahui pengaruh terpaan pemberitaan media massa dan tingkat kepercayaan masyarakat pada kompetensi Jokowi sebagai pemimpin terhadap minat masyarakat memilih Jokowi sebagai capres. Teori yang digunakan adalah teori Dependensi Efek Komunikasi Massa. Jumlah populasi sebanyak 36.711 penduduk yang berada di kelurahan Sendangmulyo, Semarang. Penelitian ini menggunakan teknik multistage random sampling diambil sampel sebanyak 100 orang. Data primer dianalisis menggunakan uji validitas, uji reliabilitas, uji asumsi klasik dan regresi linier sederhana dengan bantuan program SPPS.Perhitungan statistik menunjukkan bahwa signifikansi level terpaan pemberitaan media massa terhadap tingkat kepercayaan masyarakat pada kompetensi Jokowi sebagai pemimpin melebihi batas toleransi yaitu 0,075. Sementara, persamaan regresi linier sederhana antara tingkat kepercayaan masyarakat pada kompetensi Jokowi sebagai pemimpin terhadap minat masyarakat memilih Jokowi sebagai capres adalah Y = -0,501+0,021Z dengan nilai signifikansi 0.000. Berdasarkan hasil penelitian tersebut menunjukan bahwa terpaan pemberitaan media massa tidak berpengaruh terhadap tingkat kepercayaan masyarakat pada kompetensi Jokowi sebagai pemimpin, namun tingkat kepercayaan masyarakat pada kompetensi Jokowi berpengaruh positif terhadap minat masyarakat memilih Jokowi sebagai capres.Media massa hendaknya melakukan tugas sesuai dengan fungsinya yaitu fungsi sebagai media informasi, pendidikan, dan kontrol sosial dan melaksanakan praktik jurnalisme yang bertanggung jawab. Hal ini bertujuan untuk membangun masyarakat yang kritis dalam memperoleh dan mengolah informasi bagi keberlangsungan sistem demokrasi yang lebih baik
A Critical Review on the Development of Ionic Liquids-Based Nanofluids as Heat Transfer Fluids for Solar Thermal Energy
In recent years, solar thermal energy (STE) has attracted energy researchers because of its higher efficacy compared to the photovoltaic solar cell. STE is one of the forms of solar energy whereby heat is transferred via a secondary medium called heat transfer fluids (HTFs). Therefore, the overall performance of STE depends on the thermophysical properties and thermal performance of the HTFs. Traditional HTFs suffer from low decomposition temperature, high melting point, and higher vapor pressure. To overcome these limitations, researchers have recently begun working on new HTFs for STE. Ionic liquids (ILs) are considered as a potential candidate for the next generation of HTFs because of their enhanced thermophysical properties, such as thermal stability at high temperature, insignificant vapor pressure, and high ionic conductivity. In addition, thermophysical properties and thermal performance of ILs can be further enhanced by dispersing nanoparticles, which is one of the emerging research interests to improve the efficiency of the solar thermal system. This paper summarizes the recent study of ILs-based nanofluids as HTFs. These summaries are divided into two sections (i) thermophysical properties studies, such as density, viscosity, thermal conductivity, and heat capacity, and (ii) thermal performance studies such as natural convection and forced convection. Synthesis of ILs-based nanofluids and thermophysical properties measurement techniques are also discussed. Based on these state-of-the-art summaries, we offer recommendations for potential future research direction for ILs-based nanofluids
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Design and Factory Test of the E /E- Frascati Linear Accelerator for DAFNE
The electron-positron accelerator for the DAFNE project has been built and is in test at Titan Beta in Dublin, CA. This S-Band RF linac system utilizes four 45 MW sledded klystrons and 16-3 m accelerating structures to achieve the required performance. It delivers a 4 ampere electron beam to the positron converter and accelerates the resulting positrons to 550 MeV. The converter design uses a 4.3T pulsed tapered flux compressor along with a pseudo-adiabatic tapered field to a 5 KG solenoid over the first two positron accelerating sections. Quadrupole focusing is used after 100 MeV. The system performance is given in Table 1. This paper briefly describes the design and development of the various subassemblies in this system and gives the initial factory test data
Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes
Background: Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development of Diabetic nephropathy (DN) leading to End Stage Renal Disease. Hence a better understanding of the factors affecting kidney disease progression in T1D is urgently needed. In recent years microRNAs have emerged as important post-transcriptional regulators of gene expression in many different health conditions. We hypothesized that urinary microRNA profile of patients will differ in the different stages of diabetic renal disease. Methods and Findings: We studied urine microRNA profiles with qPCR in 40 T1D with >20 year follow up 10 who never developed renal disease (N) matched against 10 patients who went on to develop overt nephropathy (DN), 10 patients with intermittent microalbuminuria (IMA) matched against 10 patients with persistent (PMA) microalbuminuria. A Bayesian procedure was used to normalize and convert raw signals to expression ratios. We applied formal statistical techniques to translate fold changes to profiles of microRNA targets which were then used to make inferences about biological pathways in the Gene Ontology and REACTOME structured vocabularies. A total of 27 microRNAs were found to be present at significantly different levels in different stages of untreated nephropathy. These microRNAs mapped to overlapping pathways pertaining to growth factor signaling and renal fibrosis known to be targeted in diabetic kidney disease. Conclusions: Urinary microRNA profiles differ across the different stages of diabetic nephropathy. Previous work using experimental, clinical chemistry or biopsy samples has demonstrated differential expression of many of these microRNAs in a variety of chronic renal conditions and diabetes. Combining expression ratios of microRNAs with formal inferences about their predicted mRNA targets and associated biological pathways may yield useful markers for early diagnosis and risk stratification of DN in T1D by inferring the alteration of renal molecular processes. © 2013 Argyropoulos et al
Fibroblast growth factor 23 is associated with proteinuria and smoking in chronic kidney disease: An analysis of the MASTERPLAN cohort
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107913.pdf (postprint version ) (Open Access)BACKGROUND: Fibroblast growth factor 23 (FGF23) has emerged as a risk factor for cardiovascular disease and mortality throughout all stages of chronic kidney disease (CKD), independent from established risk factors and markers of mineral homeostasis. The relation of FGF23 with other renal and non-renal cardiovascular risk factors is not well established. METHODS: Using stored samples, plasma FGF23 was determined in 604 patients with moderate to severe kidney disease that participated in the MASTERPLAN study (ISRCTN73187232). The association of FGF23 with demographic and clinical parameters was evaluated using multivariable regression models. RESULTS: Mean age in the study population was 60 years and eGFR was 37 (+/- 14) ml/min/1.73 m(2). Median proteinuria was 0.3 g/24 hours [IQR 0.1-0.9]. FGF23 level was 116 RU/ml [67-203] median and IQR. Using multivariable analysis the natural logarithm of FGF23 was positively associated with history of cardiovascular disease (B = 0.224 RU/ml; p = 0.002), presence of diabetes (B = 0.159 RU/ml; p = 0.035), smoking (B = 0.313 RU/ml; p < 0.001), phosphate level (B = 0.297 per mmol/l; p = 0.0024), lnPTH (B = 0.244 per pmol/l; p < 0.001) and proteinuria (B = 0.064 per gram/24 hrs; p = 0.002) and negatively associated with eGFR (B = -0.022 per ml/min/1.73 m(2); p < 0.001). CONCLUSIONS: Our study demonstrates that in patients with CKD, FGF23 is related to proteinuria and smoking. We confirm the relation between FGF23 and other cardiovascular risk factors
Aldosterone Antagonists in Monotherapy Are Protective against Streptozotocin-Induced Diabetic Nephropathy in Rats
Angiotensin converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) are the standard clinical therapy of diabetic nephropathy (DN), while aldosterone antagonists are only used as adjuncts. Previously in experimental DN we showed that Na/K ATPase (NKA) is mislocated and angiotensin II leads to superimposed renal progression. Here we investigated the monotherapeutic effect of aldosterone blockers on the progression of DN and renal NKA alteration in comparison to ACEi and ARBs. Streptozotocin-diabetic rats developing DN were treated with aldosterone antagonists; ACEi and ARB. Renal function, morphology, protein level and tubular localization of NKA were analyzed. To evaluate the effect of high glucose per se; HK-2 proximal tubular cells were cultured in normal or high concentration of glucose and treated with the same agents. Aldosterone antagonists were the most effective in ameliorating functional and structural kidney damage and they normalized diabetes induced bradycardia and weight loss. Aldosterone blockers also prevented hyperglycemia and diabetes induced increase in NKA protein level and enzyme mislocation. A monotherapy with aldosterone antagonists might be as, or more effective than ACEi or ARBs in the prevention of STZ-induced DN. Furthermore the alteration of the NKA could represent a novel pathophysiological feature of DN and might serve as an additional target of aldosterone blockers
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