72 research outputs found
Pluri-Canonical Models of Supersymmetric Curves
This paper is about pluri-canonical models of supersymmetric (susy) curves.
Susy curves are generalisations of Riemann surfaces in the realm of super
geometry. Their moduli space is a key object in supersymmetric string theory.
We study the pluri-canonical models of a susy curve, and we make some
considerations about Hilbert schemes and moduli spaces of susy curves.Comment: To appear in the proceedings of the intensive period "Perspectives in
Lie Algebras", held at the CRM Ennio De Giorgi, Pisa, Italy, 201
Divorce, divorce rates, and professional care seeking for mental health problems in Europe: a cross-sectional population-based study
Background: Little is known about differences in professional care seeking based on marital status. The few existing studies show more professional care seeking among the divorced or separated compared to the married or cohabiting. The aim of this study is to determine whether, in a sample of the European general population, the divorced or separated seek more professional mental health care than the married or cohabiting, regardless of self-reported mental health problems. Furthermore, we examine whether two country-level features-the supply of mental health professionals and the country-level divorce rates-contribute to marital status differences in professional care-seeking behavior.
Methods: We use data from the Eurobarometer 248 on mental well-being that was collected via telephone interviews. The unweighted sample includes 27,146 respondents (11,728 men and 15,418 women). Poisson hierarchical regression models were estimated to examine whether the divorced or separated have higher professional health care use for emotional or psychological problems, after controlling for mental and somatic health, sociodemographic characteristics, support from family and friends, and degree of urbanization. We also considered country-level divorce rates and indicators of the supply of mental health professionals, and applied design and population weights.
Results: We find that professional care seeking is strongly need based. Moreover, the divorced or separated consult health professionals for mental health problems more often than people who are married or who cohabit do. In addition, we find that the gap between the divorced or separated and the married or cohabiting is highest in countries with low divorce rates.
Conclusions: The higher rates of professional care seeking for mental health problems among the divorced or separated only partially correlates with their more severe mental health problems. In countries where marital dissolution is more common, the marital status gap in professional care seeking is narrower, partially because professional care seeking is more common among the married or cohabiting
Visibility of Diversity within Association of Research Libraries Websites
Libraries in the United States have worked towards developing more inclusive environments and programs. This inclusiveness should also extend to the online library presence. This article provides results of a web page scan of all Association of Research Libraries (ARL) in the United States to document the visibility of diversity on their pages. A discussion of the importance of this visibility and examples and recommendations for website design to include diversity elements are also provided.published or submitted for publicationis peer reviewe
Impact of plasma concentration of transferrin on targeting capacity of nanoparticles
It is becoming increasingly accepted that various diseases have a capacity to alter the composition of plasma proteins. This alteration in protein composition may consequently change the targeting capacity of nanoparticles (NPs). In this study, the impact of a model targeting ligand's (i.e., Transferrin; Tf) concentration in human plasma on the targeting capacity of gold NPs (Au NPs), pre-conjugated with Tf, is investigated. Our findings demonstrate that the protein corona formation by both healthy and Tf depleted human plasma diminishes the targeting efficacy of Au NPs within human cancer cells despite a preservation of targeting ability by plasma with excess Tf (10-fold). Moreover, the plasma samples obtained from patients with various Tf levels (e.g., thalassemia major, sickle cell anemia, aplastic anemia, and iron deficiency anemia) have affected the accessibility of the targeting Tf in the corona layer and subsequently affected their targeting ability, which emphasizes the critical role of disease-specific protein corona on the efficacy of Au NPs. Ultimately, variations of protein concentration (e.g., due to disease occurrence and progress) in plasma affect its recruiting in corona formation, and in turn, affect the targeting and therapeutic efficacies of Au NPs. © The Royal Society of Chemistry 2020
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