228 research outputs found

    Influence of Mac Arthur Journal Donation Project on Serial Resources of Selected University Libraries in Nigeria

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    This study was carried out to assess the Mac Arthur Journal Donation Project in Selected University Libraries in Nigeria. Four research questions were posed in order to assess the Mac Arthur Journal Donation Project before, during and after the Donation. The research adopted survey method using questionnaire as instrument for data collection. Data collected were subjected to a descriptive analysis using frequency tables with graphical illustrations. The study discovered that the serial resources in these university libraries were inadequate before the intervention of Mac Arthur but improved substantially during and after the intervention. Consultation of serial resources was low before the intervention as majority of readers were dissatisfied with the serial resources that were available. The intervention brought an upward reversal in the resources and level of consultation. The study concluded that the intervention positively impacted on these university libraries through increased acquisition of current resources and their use. It recommended improved funding, training of staff, formation of consortia groups, library donations etc as measures to keep these university libraries alive

    Potential of Barriers to Proceedings in Court Using Internet

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    Article 2 paragraph (4) the Law Number 48 of 2009 concerning Judicial Power provides that judicial proceedings are conducted in a simple, quick, and low-cost manner. The entire scope of the court proceedings in Indonesia is basically divided into three parts, namely: the answering process of the parties, the process of evidence, and the decision making process. The use of internet media facilities is applied in the process of answering to each procedural law of all courts in Indonesia. It is necessary to have technical instructions regarding the mechanism contained in the Supreme Court Regulations and the Republic of Indonesia's Constitutional Court Regulations as guidelines for court administering courts.  Keywords: Obstacle to Court Proceeding, Internet. DOI: 10.7176/JLPG/89-06 Publication date:September 30th 2019

    Effect of foliar application of zinc and salicylic acid on growth, flowering and chemical constitute of African marigold cv. pusa narangi gainda (Targets erecta L.)

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    A field experiment on African marigold (Targets erecta L.) was conducted during winter season of 2014-15to study the foliar effect of Zn and SA of 20 treatment combinations having five concentrations of zinc (0.0, 0.25, 0.50, 0.75, and 1.0 %) and salicylic acid (0.0, 0.25, 0.50 and 1.0 mM/L).The treatmentZn4SA3 (Zinc 1% + Salicylic acid 1.0 mM/L) recorded the maximum plant height (77.41 cm), number of leaves per plant (314.10),earliest first flower bud appearance (39.78 days), maximum number of flowers per plant (62.33), maximum chlorophyll content (3.83mg/g) and maximum carotene content (3.07 mg/g)as compared to control where it was recorded minimum. These results are conclusive that foliar spraying with zinc 1.0% + salicylic acid 1.0 mM/L may positively increasedthe growth and flowering parametersof marigold

    Dangerous Liaisons: Circulating Tumor Cells (CTCs) and Cancer-Associated Fibroblasts (CAFs)

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    The crosstalk between cancer cells and the tumor microenvironment (TME) is a key determinant of cancer metastasis. Cancer-associated fibroblasts (CAFs), one of the main cellular components of TME, promote cancer cell invasion and dissemination through mechanisms including cell-cell interactions and the paracrine secretion of growth factors, cytokines and chemokines. During metastasis, circulating tumor cells (CTCs) are shed from the primary tumor to the bloodstream, where they can be detected as single cells or clusters. The current knowledge about the biology of CTC clusters positions them as key actors in metastasis formation. It also indicates that CTCs do not act alone and that they may be aided by stromal and immune cells, which seem to shape their metastatic potential. Among these cells, CAFs are found associated with CTCs in heterotypic CTC clusters, and their presence seems to increase their metastatic efficiency. In this review, we summarize the current knowledge on the role that CAFs play on metastasis and we discuss their implication on the biogenesis, metastasis-initiating capacity of CTC clusters, and clinical implications. Moreover, we speculate about possible therapeutic strategies aimed to limit the metastatic potential of CTC clusters involving the targeting of CAFs as well as their difficulties and limitations

    Sex-based Differences in C. elegans Responsiveness to Aversive Stimuli

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    Behavioral differences between sexes are evident across many species. The underlying mechanisms surrounding such differences are not fully elucidated, however, due to the complexities of animal behavior. The nematode Caenorhabditis elegans (C. elegans) is a well-characterized, genetically amenable species with two sexes, hermaphrodites (XX) and males (XO). This makes it an appropriate model system for investigating sex-based behavioral differences. Chemosensation in C. elegans is mediated by exposed ciliated sensory neurons, one of which is ASH. ASH is a polymodal nociceptor that elicits reversal when an animal encounters aversive stimuli. We hypothesized that hermaphrodite and male C. elegans worms respond differently to stimuli detected by ASH such as the bitter tastant quinine, the detergent sodium dodecyl sulfate (SDS), and the heavy metal copper (CuCl2). Wild-type assay-age hermaphrodites and males were picked from a nematode growth media (NGM) plate with E. coli OP50 and kept on an NGM plate without food for 10 minutes prior to assaying. A drop of aversive stimulus was placed in front of a forward-moving animal, and the animal’s response was recorded. A positive response is backwards movement within 4 seconds after contact with the stimulus. Our results reveal a quantifiable difference in how wild-type hermaphrodite and male C. elegans respond to aversive stimuli. Specifically, wild-type males are less responsive than hermaphrodites to quinine, SDS, and CuCl2. Further investigations will be conducted through experiments with C. elegans strains in which hermaphrodites have masculinized, and males have feminized nervous systems or subsets of neurons. Through these experiments, we aim to explore potential sites of difference that lead to these observable differences in responsiveness to aversive stimuli

    Early critical care course in children after liver transplant

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    Objective. To review the critical care course of children receiving orthotopic liver transplantation (OLT)

    Undiagnosed Hypertension and Proteinuria in a Market Population in Ile-Ife, Nigeria

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    Introduction: Hypertension and chronic kidney disease (CKD) are common in our urban and rural communities but the majority of affected individuals are not aware of their condition. We conducted free medical examination and screening during one of the market days in Odo-Ogbe market, Ile-Ife, Nigeria to evaluate the magnitude of undiagnosed hypertension and proteinuria. Methods: Participants were taken through a brief medical history and had their socio-demographic data taken. Weight and height were measured and body mass index (BMI) calculated. Blood pressure (BP) was measured using a mercury sphygmomanometer and urinalysis was done with the aid of dipstick test. Results: A total of 286 participants aged 13-90 years (Mean 49.5 ± 15.7 years) were screened. Females constituted 90.2% of the study population. One-hundred and eight (37.7%) of participants had hypertension and only 20 (6.7%) were previously diagnosed. Sixty-nine participants (24.1%) had stage-1 hypertension while 39 (13.6%) had stage-2 hypertension. Fifty-nine percent of participants had BMI above 25 kg/m2. Eighty five participants (29.7%) had proteinuria while only 13 (4.5%) had glycosuria. A significantly higher percentage of participants with stage-1 and stage-2 hypertension had proteinuria compared with non hypertensives. There was a positive correlation between age and BMI (r = 0.171, P = 0.004), age and systolic BP (r = 0.378, P < 0.0001) as well as age and diastolic BP (r = 0.197, P = 0.001). Conclusion: A high percentage of the studied population (31%) had undiagnosed hypertension and proteinuria (29.7%). Community screening for these disabling non communicable diseases and lifestyle modifications should be encouraged.Keywords: Africans; Blacks; Hypertension; Kidney Disease; Proteinuria; ESR

    Mobilisation Du Foncier Au Profit Des Investissements Immobiliers Publics Dans La Commune D’Abomey-Calavi

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    Pour faire face à l’évolution démographique et à l’augmentation de la demande de logement dans la ville d’Abomey-Calavi, l’Etat Béninois a initié de nombreux projets de construction de logements économiques au profit des ménages. La présente recherche vise à analyser les stratégies de mobilisation du foncier au profit de ces investissements. La méthodologie de recherche s’est basée sur les recherches documentaires, la collecte de données auprès de 113 personnes par entretien et questionnaire, le traitement de ces données et l’analyse des résultats par le biais du modèle SWOT ou FFOM (Forces, Faiblesses, Opportunités et Menaces).Les résultats obtenus montrent que deux principales stratégies sont utilisées par les autorités pour mobiliser le foncier pour la  construction de logements sociaux.  Il s’agit de la constitution de réserves administratives à l’issue des opérations de lotissement  et de l’expropriation foncière pour cause d’utilité publique.  Au total, 539 réserves administratives ont été constituées dans la Commune d’Abomey-Calavi et environ 3 457 ha de domaines ont été expropriés au profit des programmes immobiliers. Trente-deux (32) logements de type F2, soixante-quinze (75) logements de type F3 et quarante-cinq (45) logements de type F4 ont été construits sur le site de la Zopah à Abomey-Calavi en 2008. De même, il est prévu la construction de 200 logements de type F2, 500 logements de type F3 et 300 logements de type F4 sur un premier site  dans l’Arrondissement de Ouèdo.  Sur un second site du même arrondissement, 8900 logements sont en cours de construction dont 3035 sont pratiquement achevés.  Malgré ces efforts en termes d’investissements,  les ménages font évoquent  des insuffisances qui ne facilitent pas un accès équitable et juste  auxdits logements. . Pour 75% des personnes interrogées, ces logements seraient trop chers ; 20% trouvent que ces logements sont exigus, et 5% trouvent que leurs plans architecturaux ne conviennent pas aux besoins des ménages. Il paraît donc  important que les autorités publiques travaillent davantage à l’ancrage socio-économique de ces logements pour faciliter leur acquisition et leur occupation par les ménages
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