Mobile Apps as Supplements of a Typical Discrete Mathematics Course: Benefits, Features, and Design Elements

Mobile Apps have tremendous potential for use as very effective supplements to the exiting learning modalities in a typical introductory Discrete Mathematics course. In this article we consider the general nature of a typical introductory Discrete Mathematics courses and derive elements of design which are expected to make the mobile Apps intended for use as supplements to such a course more effective. We enumerate the elements of the topical coverage and inherent characteristics of typical introductory Discrete Mathematics course, and the benefits of a mobile App course supplement. We then present the design aspects and desired salient features of mobile Apps intended for uses as supplements in a typical introductory Discrete Mathematics course, and the elements of user experience (UX) of such an App. We believe that several of these design elements could be adapted across several different courses and disciplines to enhance the learning experience

Performance Evaluation of Hybrid Coding of Images Using Wavelet Transform and Predictive Coding

Image compression techniques are necessary for the storage of huge amounts of digital images using reasonable amounts of space, and for their transmission with limited bandwidth. Several techniques such as predictive coding, transform coding, subband coding, wavelet coding, and vector quantization have been used in image coding. While each technique has some advantages, most practical systems use hybrid techniques which incorporate more than one scheme. They combine the advantages of the individual schemes and enhance the coding effectiveness. This paper proposes and evaluates a hybrid coding scheme for images using wavelet transforms and predictive coding. The performance evaluation is done using a variety of different parameters such as kinds of wavelets, decomposition levels, types of quantizers, predictor coefficients, and quantization levels. The results of evaluation are presented

Rate-Based End-to-End Congestion Control of Multimedia Traffic in Packet Switched Networks

This paper proposes an explicit rate-based end-to-end congestion control mechanism to alleviate congestion of multimedia traffic in packet switched networks such as the Internet. The congestion is controlled by adjusting the transmission rates of the sources in response to the feedback information from destination such as the buffer occupancy, packet arrival rate and service rate at the outgoing link, so that a desired quality of service (QoS) can be met. The QoS is defined in terms of packet loss ratio, transmission delay, power, and network utilization. Comparison studies demonstrate the effectiveness of the proposed scheme over New-Reno TCP (a variant of AIMD: additive increase multiplicative decrease) technique during simulated congestion. Since it is end-to-end, no router support is necessary, the proposed methodology can be readily applied to today\u27s Internet, as well as for real-time video and voice data transfer in unicast networks

Adaptive Bus Routing Heuristics for Improving Vehicle Utilization and Reducing Commuter Waiting Times

ABSTRACT: Millions of people in cities around the world, especially in the developing and underdeveloped countries, depend on the (intra-city) public bus system to get to work and back home. In most cases, the system is strained -there are demands for more buses and routes than available. This has led to increased waiting times of the commuters. Also, since the routes are 'static', this might lead to underutilization of the buses. In this paper, we propose a system which makes use of sensors, and computing and wireless/mobile technologies in the buses and bus stops, and a central scheduler which gathers streaming data from the buses and bus stops and uses heuristics to determine in realtime 'adaptive' routes for the buses. These are expected to reduce the waiting times of commuters and increase the utilization of the buses

Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus

Serine hydroxymethyltransferase (SHMT), a member of the α-class of pyridoxal phosphate-dependent enzymes, catalyzes the reversible conversion of serine to glycine and tetrahydrofolate to 5,10-methylene tetrahydrofolate. We present here the crystal structures of the native enzyme and its complexes with serine, glycine, glycine, and 5-formyl tetrahydrofolate (FTHF) from Bacillus stearothermophilus. The first structure of the serine-bound form of SHMT allows identification of residues involved in serine binding and catalysis. The SHMT-serine complex does not show any significant conformational change compared with the native enzyme, contrary to that expected for a conversion from an "open" to "closed" form of the enzyme. However, the ternary complex with FTHF and glycine shows the reported conformational changes. In contrast to the Escherichia coli enzyme, this complex shows asymmetric binding of the FTHF to the two monomers within the dimer in a way similar to the murine SHMT. Comparison of the ternary complex with the native enzyme reveals the structural basis for the conformational change and asymmetric binding of FTHF. The four structures presented here correspond to the various reaction intermediates of the catalytic pathway and provide evidence for a direct displacement mechanism for the hydroxymethyl transfer rather than a retroaldol cleavage

Magnetic stress as a driving force of structural distortions: the case of CrN

We show that the observed transition from rocksalt to orthorhombic P$_{nma}$ symmetry in CrN can be understood in terms of stress anisotropy. Using local spin density functional theory, we find that the imbalance between stress stored in spin-paired and spin-unpaired Cr nearest neighbors causes the rocksalt structure to be unstable against distortions and justifies the observed antiferromagnetic ordering. This stress has a purely magnetic origin, and may be important in any system where the coupling between spin ordering and structure is strong.Comment: 4 pages (two columns) 4 figure

HOST SPECIES PREFERENCE AND FLOWER BUD PARAMETER INFLUENCING THE BUD DAMAGE IN JASMINE

ABSTRACT Among the five jasmine species considered, only Jasmine multiflorum and Jasmine sambac were infested by the bud borers. Variation in flower bud and cluster characteristics were observed among different jasmine species. The mean number of buds per cluster and inter cluster distance was high in Jasmine multiflorum compared to other species. Whereas inter bud distance was lower in case of Jasmine multiflorum and Jasmine rigidium. Bud length and weight was higher in Jasmine multiflorum while the bud diameter was greater in Jasmine sambac. There was high positive correlation between bud damage and the number of buds present in a cluster and bud weight hence Jasmine multiflorum more prone to damage by bud borers. The larvae of both the bud borers E. jasminophagus and H. duplifasciatus damaged green buds, white buds and open flowers of Jasmine multiflorum. There was a high positive correlation between the total bud availability and the extent of damage. Earlier larval instar preferred green buds, while later larval instars preferred white buds and open flowers

Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD

The helicase PcrA unwinds DNA during asymmetric replication of plasmids, acting with an initiator protein, in our case RepD. Detailed kinetics of PcrA activity were measured using bulk solution and a single-molecule imaging technique to investigate the oligomeric state of the active helicase complex, its processivity and the mechanism of unwinding. By tethering either DNA or PcrA to a microscope coverslip surface, unwinding of both linear and natural circular plasmid DNA by PcrA/RepD was followed in real-time using total internal reflection fluorescence microscopy. Visualization was achieved using a fluorescent single-stranded DNA-binding protein. The single-molecule data show that PcrA, in combination with RepD, can unwind plasmid lengths of DNA in a single run, and that PcrA is active as a monomer. Although the average rate of unwinding was similar in single-molecule and bulk solution assays, the single-molecule experiments revealed a wide distribution of unwinding speeds by different molecules. The average rate of unwinding was several-fold slower than the PcrA translocation rate on single-stranded DNA, suggesting that DNA unwinding may proceed via a partially passive mechanism. However, the fastest dsDNA unwinding rates measured in the single-molecule unwinding assays approached the PcrA translocation speed measured on ssDNA

Competition between Magnetic and Structural Transition in CrN

CrN is observed to undergo a paramagnetic to antiferromagnetic transition accompanied by a shear distortion from cubic NaCl-type to orthorhombic structure. Our first-principle plane wave and ultrasoft pseudopotential calculations confirm that the distorted antiferromagnetic phase with spin configuration arranged in double ferromagnetic sheets along [110] is the most stable. Antiferromagnetic ordering leads to a large depletion of states around Fermi level, but it does not open a gap. Simultaneous occurence of structural distortion and antiferromagnetic order is analyzed.Comment: 10 pages, 10 figure

Diacylglycerol-Stimulated Endocytosis of Transferrin in Trypanosomatids Is Dependent on Tyrosine Kinase Activity

Small molecule regulation of cell function is an understudied area of trypanosomatid biology. In Trypanosoma brucei diacylglycerol (DAG) stimulates endocytosis of transferrin (Tf). However, it is not known whether other trypanosomatidae respond similarly to the lipid. Further, the biochemical pathways involved in DAG signaling to the endocytic system in T. brucei are unknown, as the parasite genome does not encode canonical DAG receptors (e.g. C1-domains). We established that DAG stimulates endocytosis of Tf in Leishmania major, and we evaluated possible effector enzymes in the pathway with multiple approaches. First, a heterologously expressed glycosylphosphatidylinositol phospholipase C (GPI-PLC) activated endocytosis of Tf 300% in L. major. Second, exogenous phorbol ester and DAGs promoted Tf endocytosis in L. major. In search of possible effectors of DAG signaling, we discovered a novel C1-like domain (i.e. C1_5) in trypanosomatids, and we identified protein Tyr kinases (PTKs) linked with C1_5 domains in T. brucei, T. cruzi, and L. major. Consequently, we hypothesized that trypanosome PTKs might be effector enzymes for DAG signaling. General uptake of Tf was reduced by inhibitors of either Ser/Thr or Tyr kinases. However, DAG-stimulated endocytosis of Tf was blocked only by an inhibitor of PTKs, in both T. brucei and L. major. We conclude that (i) DAG activates Tf endocytosis in L. major, and that (ii) PTKs are effectors of DAG-stimulated endocytosis of Tf in trypanosomatids. DAG-stimulated endocytosis of Tf may be a T. brucei adaptation to compete effectively with host cells for vertebrate Tf in blood, since DAG does not enhance endocytosis of Tf in human cells