24 research outputs found

    Applications of electrospinning/electrospraying in drug delivery

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    Association of healthy food intake with psychiatric distress in children and adolescents: The CASPIAN-IV study

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    Background: Healthy dietary habits are known as a key factor for improving brain functions and cognitive ability in children and adolescents. The goal of this study was to evaluate the association of healthy food consumption with mental health in Iranian children and adolescents. Materials and Methods: Data were obtained from the fourth national school-based surveillance survey entitled CASPIAN-IV study. In this study, 14880 children and adolescents aged 6-18 years were selected by multistage, cluster sampling method from rural and urban areas. The students and their parents completed two sets of questionnaires. The psychiatric distress included depression, worry, insomnia, anxiety, aggression, confusion, and worthless and the violent behaviors comprised of physical fight, victim and bully. The healthy foods included fresh fruits, dried fruits, vegetables and dairy products. Results: The participants include 13,486 students from elementary, intermediate and high school degree. The prevalence of psychiatric distress was significantly higher among high school students, while violent behaviors were more prevalent in the middle school students. According to the multivariate model (model IV), the risk of psychiatric distress was significantly lower in students with daily consumption of fresh fruits, vegetables and milk. In addition, those with daily consumption of vegetables and milk had significantly lower risk for violent behaviors. Conclusion: Consumption of healthy foods may reduce the risk of psychiatric distress and violent behaviors. Therefore, in addition to its benefits, increasing healthy food consumption among children and adolescents can be useful in preventing mental health disorders

    Association of healthy food intake with psychiatric distress in children and adolescents: The CASPIAN-IV study

    No full text
    Background: Healthy dietary habits are known as a key factor for improving brain functions and cognitive ability in children and adolescents. The goal of this study was to evaluate the association of healthy food consumption with mental health in Iranian children and adolescents. Materials and Methods: Data were obtained from the fourth national school-based surveillance survey entitled CASPIAN-IV study. In this study, 14880 children and adolescents aged 6-18 years were selected by multistage, cluster sampling method from rural and urban areas. The students and their parents completed two sets of questionnaires. The psychiatric distress included depression, worry, insomnia, anxiety, aggression, confusion, and worthless and the violent behaviors comprised of physical fight, victim and bully. The healthy foods included fresh fruits, dried fruits, vegetables and dairy products. Results: The participants include 13,486 students from elementary, intermediate and high school degree. The prevalence of psychiatric distress was significantly higher among high school students, while violent behaviors were more prevalent in the middle school students. According to the multivariate model (model IV), the risk of psychiatric distress was significantly lower in students with daily consumption of fresh fruits, vegetables and milk. In addition, those with daily consumption of vegetables and milk had significantly lower risk for violent behaviors. Conclusion: Consumption of healthy foods may reduce the risk of psychiatric distress and violent behaviors. Therefore, in addition to its benefits, increasing healthy food consumption among children and adolescents can be useful in preventing mental health disorders

    Osteoporosis and cognitive impairment interwoven warning signs: community-based study on older adults—Bushehr Elderly Health (BEH) Program

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    Summary: Cognitive impairment and osteoporosis are frequently seen to coincide in clinical practice. Osteoporosis was higher in elderly populations with cognitive impairment, especially in postmenopausal women. Thus, prophylaxis for osteoporosis, falls, and fractures should be considered as part of the treatment of patients with cognitive impairment. Introduction: Cognitive impairment and osteoporosis are two important health concerns among older adults that their possible relationship, concurrent occurrence, and linking mechanism have recently been highlighted. The purpose of this study was to assess the sex-independent association of these two conditions. Materials and methods: From among 2331 individuals aged ≥ 60 years selected in Bushehr Elderly Health (BEH) Program, Iran; data of 1508 participants were analyzed. Cognitive status was assessed using Category Fluency Test and Mini-cog assessment instrument. Association between osteopenia–osteoporosis and cognitive impairment were assessed using uni- and multivariable logistic regression models. Results: Osteoporosis was diagnosed in 598 (39.6%) of the participants (58.3% female and 21.9% male, P < 0.001). From among them, 677 (44.9%) had evidence of cognitive impairment (64.5% female and 31.0% male, P < 0.001). Multivariate logistic regressions showed spinal and total hip osteoporosis was associated with 1.83 (CI 95% 1.13–2.96) and 2.24-fold (CI 95% 1.28–3.89) increase in the risk of cognitive impairment among female subjects, respectively. Ordinal logistic regression, on the other hand, revealed cognitive impairment to be associated with 1.42-fold (CI 95% 1.04–1.92) increase in the risk of spinal osteopenia–osteoporosis, 1.5-fold increase in total hip osteoporosis (CI 95% 1.09–2.05), and 1.48-fold increase in general osteoporosis (CI 95% 1.06–2.0). Conclusion: Different degrees of bone loss and cognitive impairment may be a risk factor for each other among women but not in men. It is suggested that the screening, adopting preventive measures for the other condition and regular follow-ups, if needed, could be of utmost importance

    Bone characteristics and metabolic phenotypes of obesity in an Iranian Elderly population: Bushehr Elderly Health Program (BEHP)

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    Introduction Obesity and osteoporosis are health problems with high impact on the morbidity and mortality rate. While the association between BMI and bone density is known, the combined effects of obesity and metabolic components on bone health have not yet been revealed. The objectives of this study were to determine the association between bone health and different phenotypes of obesity in an elderly population. Methods This cross-sectional study was conducted on the data collected in the Bushehr Elderly Health Program (BEHP). The participants were classified in four groups based on the metabolic phenotypes of obesity (metabolic healthy obese (MHO), metabolic non-healthy non-obese (MNHNO), metabolic non-healthy obese (MNHO), and metabolic healthy non-obese (MHNO)). The association between osteoporosis and TBS and the metabolic phenotypes of obesity were assessed using multiple variable logistic regression models. Results Totally, 2378 people (1227 women) were considered for analyses. The prevalence of MHNO, MHO, MNHNO, and MNHO were 902 (39.9%), 138 (6.1%), 758 (33.5%), and 464 (20.5%), respectively. In the multivariate logistic regression models, those with MHO (OR 0.22; 95% CI 0.12–0.36), MNHNO (OR 0.52; 95% CI 0.4–0.66), and MNHO phenotypes (OR 0.22; 95% CI 0.16–0.3) had a significantly lower risk of osteoporosis. Likewise, those having MHO (OR 2.38; 95% CI 1.51–3.76), MNHNO (OR 1.49; 95% CI 1.11–2), and MNHO (OR 2.50; 95% CI 1.82–3.42) phenotypes were found to had higher risk of low bone quality as confirmed by TBS. Conclusions The obese subjects have lower bone quality, regardless of their obesity phenotype
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