High-Frequency Jet Ventilation During Cryoablation of Small Renal Tumours

AIM: To evaluate the effect of high-frequency jet ventilation (HFJV) in place of standard intermittent positive-pressure ventilation (IPPV) on procedure duration, patient radiation dose, complication rates, and outcomes during CT-guided cryoablation of small renal tumours. MATERIALS AND METHODS: One hundred consecutive CT-guided cryoablation procedures to treat small renal tumours under general anaesthesia were evaluated-50 with standard IPPV and 50 after the introduction of HFJV as standard practice. Anaesthesia and procedural times, ionising radiation dose, complications, and 1-month post-treatment outcomes were collected. RESULTS: HFJV was feasible and safe in all cases. Mean procedure time and total anaesthetic time were shorter with HFJV (p = <0.0001). The number of required CT acquisitions (p = 0.0002) and total procedure patient radiation dose (p = 0.0027) were also lower in the HFJV group compared with the IPPV group. There were a total of four complications of Clavien-Dindo classification 3 or above-three in the IPPV group and one in the HFJV group. At 1-month follow-up, two cases (both in the IPPV group) demonstrated subtotal treatment. Both cases were subsequently successfully retreated with cryoablation. CONCLUSION: By reducing target tumour motion during CT-guided renal cryoablation, HFJV can reduce procedure times and exposure to ionising radiation. HFJV provides an important adjunct to complex image-guided interventions, with potential to improve safety and treatment outcomes

Temperature and heat flux measurement techniques for aeroengine fire test: a review

This review is made of studies whereby some types of fire test measuring instrument were compared based on their mode of operation, sensing ability, temperature resistance and their calibration mode used for aero-engine applications. The study discusses issues affecting temperature and heat flux measurement, methods of measurement, calibration and uncertainties that occur in the fire test. It is found that the temperature and heat flux measurements of the flame from the standard burner need to be corrected and taken into account for radiation heat loss. Methods for temperature and heat flux measurements, as well as uncertainties analysis, were also discussed

Mechanical properties of kenaf fibre thermoplastic polyurethane-natural rubber composites

Thermoplastic polyurethane-natural rubber TPUR-NR composites filled with treated and untreated kenaf fiber as filler were prepared at different TPUR and NR contents. The content of kenaf fiber was maintained at 12.5 wt % and the fiber was treated with 6 % solution of sodium hydroxide (NaOH), then dried for 24 hours in 100 °C, hot blended with polymer components, pulverized and pressed. The mechanical properties of the composites such as tensile, flexural and impact strength were determined, and their dependence on NaOH treatment of kenaf fibers was investigated. The analysis using scanning electron microscope (SEM) was implemented to identify the effect of alkali treatment on the microstructure of kenaf fiber and TPUR-NR composites. An improvement of fiber surface roughness and bonding between the fiber and polymer as well as an increase in impact energy and elongation at break of the composites was observed

Selection of Natural Fiber for Hybrid Kevlar/Natural Fiber Reinforced Polymer Composites for Personal Body Armor by Using Analytical Hierarchy Process

Kevlar 29 is the most widely used synthetic fiber for body armor applications and they have been derived from petroleum based resources. Depletion of petroleum resources and the increase in awareness about the eco-friendly materials encouraged the researchers to explore the potential use of natural fiber as an alternative for synthetic fibers. Hybridization of natural fiber with synthetic fiber will result in unique properties which is difficult to obtain from the individual fibers. In this research Analytical Hierarchy Process (AHP) was used to identify the most suitable natural fiber to be hybridized with Kevlar 29 fiber as a reinforcement in the polymer composites for personal body armor. Fourteen natural fibers and seven criteria's were selected and analyzed for hybridization with respect to the personal body armors design specification. Cocos nucifera sheath which is a naturally woven fiber yields the highest priority vector and it was selected as a most promising natural fiber for hybridization with Kevlar 29 for personal body armor. Eventually, sensitivity analysis was carried out to check the stability of the priority ranking

Effect of cuscuta reflexa stem and calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice

Cuscuta reflexa (whole plant) and Calotropis procera (leaves) are used in folk medicine of Bangladesh to control blood sugar in patients suffering from diabetes mellitus. The hypoglycemic effects of methanol and chloroform extracts of whole plants of Cuscuta reflexa, and methanol extract of leaves of Calotropis procera were investigated in oral glucose tolerance tests in Long Evans rats and Swiss albino mice, respectively. Both methanol and chloroform extracts of Cuscuta reflexa whole plant demonstrated significant oral hypoglycemic activity in glucose-loaded rats at doses of 50, 100 and 200 mg/kg body weight. The methanol extract of leaves of Calotropis procera, when tested at doses of 100 and 250 mg/kg body weight did not demonstrate any oral hypoglycemic effect when tested in glucose-loaded mice.Key words: Cuscuta reflexa, Calotropis procera, hypoglycemic activity, oral glucose tolerance test

Comparison of two interferon-gamma release assays (QuantiFERON-TB Gold In-Tube and T-SPOT.TB) in testing for latent tuberculosis infection among HIV-infected adults.

There is currently no 'gold standard' for diagnosis of latent tuberculosis infection (LTBI), and both the tuberculin skin test and interferon-gamma release assays (IGRAs) are used for diagnosis; the latter have a higher sensitivity than tuberculin skin tests for diagnosis of LTBI in HIV-infected individuals with lower CD4 counts. No evidence base exists for selection of IGRA methodology to identify LTBI among human immunodeficiency virus-infected patients in the UK. We prospectively evaluated two commercially available IGRA methods (QuantiFERON-TB Gold In Tube [QFG] and T-SPOT.TB) for testing LTBI among HIV-infected patients potentially nosocomially exposed to an HIV-infected patient with 'smear-positive' pulmonary tuberculosis. Among the exposed patients median CD4 count was 550 cells/µL; 105 (90%) of 117 were receiving antiretroviral therapy, of who 104 (99%) had an undetectable plasma HIV load. IGRAs were positive in 12 patients (10.3%); QFG positive in 11 (9.4%) and T-SPOT.TB positive in six (5.1%); both IGRAs were positive in five patients (4.3%). There was one indeterminate QFG and one borderline T-SPOT.TB result. Concordance between the two IGRAs was moderate (κ = 0.56, 95% confidence interval = 0.27-0.85). IGRAs were positive in only 4 (29%) of 14 patients with previous culture-proven tuberculosis. No patient developed tuberculosis during 20 months of follow-up

Heat transfer performance of multiple holes impingement cooling technique

This research presents the possibility of the jet impingement cooling technique configuration for stator of turbine blade under the transient heat transfer condition. The main goal of this study is to investigate the impingement cooling plate holes configura tion and Reynolds number (Re) effect on the heat transfer which can be observed from the color play of the thermochromic liquid crystal (TLC). The fin dings proved that with the present of the small holes in between the main larger holes capable to enhance the heat transfer across the target surface. However, some criteria of the design need to be taken into count as it may produce different heat transfer performan ce of the impingement cooling technique. Therefore, in the range of predetermined design parameters, only several combinations that prevailed to achieve maximum heat transfer across the target plate

Variation in gas chromatography (GC) analysis in setting up laboratory protocols for waste to energy novel fixed bed reactor setups

Gas Chromatography coupled with Mass Spectrometry (GC/MS) has been applied in various analytical chemistry works. However, to fine tune a system that can serve the purposes of pyrolysis oil identification has proven to be a laborious effort, especially when considering the fact that no standard protocol exists for such analysis. In addition, obtained products were yielded from a newly commissioned unit with a unique and novel design. In this study, a US patent office claimed reactor [SULTAN-1, Pyrolysis Reactor System for the Conversion and Analysis of Organic Solid Waste, Patent application number: 15,487,351] that degrades polyolefinc virgin and waste materials to obtain petroleum refinery and petrochemical feedstock, has been commissioned. The reactor produces three distinct physical states of matter products accumulated as testing specimens, i.e. solids, gaseous and oil. The samples analysed in this work were of the gas and oil produced by pyrolysis of end of life tyre (ELTs) shavings that required to have a special recipe to work with in the laboratory. Various MS cords were utilised and experimental setups to fine tune the process, and special emphasis was given on the gas samples variation in this communication. To reach the desired analysis results with high repeatability, a plethora of experiences of lab personnel and laboratory-based experimental work was accumulated. Laboratory protocols were also setup for this work. These will be detailed along the process execution which yielded a standard laboratory best practice analytical method as part of the State of Kuwait newly initiated Government Initiative project