A content analysis in reverse logistics: a review

The purpose of this paper is to provide a comprehensive review in the various publications on the concept of Reverse Logistics (RL) and the related areas within the period 1998-2012. The content analysis approach has been opted to collect the relevant information from different books, journals, and conferences. A broad review of literature in RL from its emergence until the recent discussions have been analyzed and compared in this research. The findings show that, the theoretical construct in RL has been initiated from the conjunction features in the waste management and logistics activities. This idea had been developed by introducing the new term as RL and its definitions and contents such as the activities; key drivers; barriers to use; material flow, and networks in RL. Furthermore, the findings present the various modelling in different aspects of RL, for instance, the mathematical modelling by applying the existence methods in Multi Attribute Decision-Making Models (MADM). In addition, the environmental concerns and governmental legislatives matters and impacts, which have been highlighted, recently, on RL have been deliberated. Hence, this paper would assist the researchers and practitioners to obtain a broad review of RL in the last decade and, also provide an agenda for the future researches

The role of the bronchial microvasculature in the airway remodelling in asthma and COPD

In recent years, there has been increased interest in the vascular component of airway remodelling in chronic bronchial inflammation, such as asthma and COPD, and in its role in the progression of disease. In particular, the bronchial mucosa in asthmatics is more vascularised, showing a higher number and dimension of vessels and vascular area. Recently, insight has been obtained regarding the pivotal role of vascular endothelial growth factor (VEGF) in promoting vascular remodelling and angiogenesis. Many studies, conducted on biopsies, induced sputum or BAL, have shown the involvement of VEGF and its receptors in the vascular remodelling processes. Presumably, the vascular component of airway remodelling is a complex multi-step phenomenon involving several mediators. Among the common asthma and COPD medications, only inhaled corticosteroids have demonstrated a real ability to reverse all aspects of vascular remodelling. The aim of this review was to analyze the morphological aspects of the vascular component of airway remodelling and the possible mechanisms involved in asthma and COPD. We also focused on the functional and therapeutic implications of the bronchial microvascular changes in asthma and COPD

Formulating and Solving Sustainable Stochastic Dynamic Facility Layout Problem: A Key to Sustainable Operations

Facility layout design, a NP Hard problem, is associated with the arrangement of facilities in a manufacturing shop floor, which impacts the performance, and cost of system. Efficient design of facility layout is a key to the sustainable operations in a manufacturing shop floor. An efficient layout design not only optimizes the cost and energy due to proficient handling but also increase flexibility and easy accessibility. Traditionally, it is solved using meta-heuristic techniques. But these algorithmic or procedural methodologies do not generate effective and efficient layout design from sustainable point of view, where design should consider multiple criteria such as demand fluctuations, material handling cost, accessibility, maintenance, waste and more. In this paper, to capture the sustainability in the layout design these parameters are considered, and a new Sustainable Stochastic Dynamic Facility Layout Problem (SDFLP) is formulated and solved. SDFLP is optimized for material handling cost and rearrangement cost using various meta-heuristic techniques. The pool of layouts thus generated is then analyzed by Data Envelopment Analysis (DEA) to identify efficient layouts. A novel hierarchical methodology of consensus ranking of layouts is proposed which combines the multiple attributes/criteria. Multi Attribute decision-making (MADM) Techniques such as Technique for Order Preference by Similarity to Ideal Solution (TOPSIS), Interpretive Ranking Process (IRP) and Analytic hierarchy process (AHP), Borda-Kendall and Integer Linear Programming based rank aggregation techniques are applied. To validate the proposed methodology data sets for facility size N=12 for time period T=5 having Gaussian demand are considered

Dynamic dispatching priority setting in customer-oriented manufacturing environments

In today's competitive environment, customer-oriented view is essential in gaining sustainable competitive advantage. This study aims to reflect the customer-oriented view to production planning and control decisions. To this aim, a simulation optimization-based approach is developed for job shop systems with dynamic order arrivals. Product-type-based lot splitting is applied in order to improve the flow time, and machine-based dispatching rules are utilized for sublot scheduling to realize dynamic scheduling. Multiple customer segments with different importance weights and their expectations and penalties on order completion rate on due date, tardiness, and earliness are considered. A customer satisfaction-based objective function is defined. Customer-oriented dispatching rules are proposed in this study to ensure the prioritization of orders from the key customers in order fulfilling. In order to prevent customer losses by providing a balanced structure between the customer segments in terms of the satisfaction levels, weight setting functions that dynamically compute the weights in the proposed dispatching rules are proposed. It is aimed to determine the near-optimal values of the segment-based parameters of the related weight setting functions. To this aim, a differential evolution algorithm-based simulation optimization approach is proposed. To confirm its viability, the proposed approach is applied to a realistic job shop system