1,770 research outputs found
Simulating quantum correlations as a distributed sampling problem
It is known that quantum correlations exhibited by a maximally entangled
qubit pair can be simulated with the help of shared randomness, supplemented
with additional resources, such as communication, post-selection or non-local
boxes. For instance, in the case of projective measurements, it is possible to
solve this problem with protocols using one bit of communication or making one
use of a non-local box. We show that this problem reduces to a distributed
sampling problem. We give a new method to obtain samples from a biased
distribution, starting with shared random variables following a uniform
distribution, and use it to build distributed sampling protocols. This approach
allows us to derive, in a simpler and unified way, many existing protocols for
projective measurements, and extend them to positive operator value
measurements. Moreover, this approach naturally leads to a local hidden
variable model for Werner states.Comment: 13 pages, 2 figure
Simulation of bipartite qudit correlations
We present a protocol to simulate the quantum correlations of an arbitrary
bipartite state, when the parties perform a measurement according to two
traceless binary observables. We show that bits of classical
communication is enough on average, where is the dimension of both systems.
To obtain this result, we use the sampling approach for simulating the quantum
correlations. We discuss how to use this method in the case of qudits.Comment: 7 page
Universal Scaling of Wave Propagation Failure in Arrays of Coupled Nonlinear Cells
We study the onset of the propagation failure of wave fronts in systems of
coupled cells. We introduce a new method to analyze the scaling of the critical
external field at which fronts cease to propagate, as a function of
intercellular coupling. We find the universal scaling of the field throughout
the range of couplings, and show that the field becomes exponentially small for
large couplings. Our method is generic and applicable to a wide class of
cellular dynamics in chemical, biological, and engineering systems. We confirm
our results by direct numerical simulations.Comment: 4 pages, 3 figures, RevTe
A Lower Bound for Quantum Phase Estimation
We obtain a query lower bound for quantum algorithms solving the phase
estimation problem. Our analysis generalizes existing lower bound approaches to
the case where the oracle Q is given by controlled powers Q^p of Q, as it is
for example in Shor's order finding algorithm. In this setting we will prove a
log (1/epsilon) lower bound for the number of applications of Q^p1, Q^p2, ...
This bound is tight due to a matching upper bound. We obtain the lower bound
using a new technique based on frequency analysis.Comment: 7 pages, 1 figur
Using the theory of planned behavior to predict gambling behavior
Gambling is an important public health concern. To better understand gambling behavior, we conducted a classroom-based survey that assessed the role of the theory of planned behavior (TPB; i.e., intentions, subjective norms, perceived behavioral control, and attitudes) in past year gambling and gambling frequency among college students. Results from this research support the utility of the TPB to explain gambling behavior in this population. Specifically, in TPB models to predict gambling behavior, friend and family subjective norms and perceived behavioral control predicted past year gambling and friend and family subjective norms, attitudes and perceived behavioral control predicted gambling frequency. Intention to gamble mediated these relationships. These findings suggest that college responsible gambling efforts should consider targeting misperceptions of approval regarding gambling behavior (i.e., subjective norms), personal approval of gambling behavior (i.e., attitudes), and perceived behavioral control to better manage gambling behavior in various situations
Treatment Options for Carbapenem-Resistant Enterobacteriaceae Infections
This article provides a comprehensive review of currently available treatment options for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance in Gram-negative bacteria is an emerging and serious global public health threat. Carbapenems have been used as the “last-line” treatment for infections caused by resistant Enterobacteriaceae, including those producing extended spectrum ß-lactamases. However, Enterobacteriaceae that produce carbapenemases, which are enzymes that deactivate carbapenems and most other ß-lactam antibiotics, have emerged and are increasingly being reported worldwide. Despite this increasing burden, the most optimal treatment for CRE infections is largely unknown. For the few remaining available treatment options, there are limited efficacy data to support their role in therapy. Nevertheless, current treatment options include the use of older agents, such as polymyxins, fosfomycin, and aminoglycosides, which have been rarely used due to efficacy and/or toxicity concerns. Optimization of dosing regimens and combination therapy are additional treatment strategies being explored. Carbapenem-resistant Enterobacteriaceae infections are associated with poor outcomes and high mortality. Continued research is critically needed to determine the most appropriate treatment
Avalanche of Bifurcations and Hysteresis in a Model of Cellular Differentiation
Cellular differentiation in a developping organism is studied via a discrete
bistable reaction-diffusion model. A system of undifferentiated cells is
allowed to receive an inductive signal emenating from its environment.
Depending on the form of the nonlinear reaction kinetics, this signal can
trigger a series of bifurcations in the system. Differentiation starts at the
surface where the signal is received, and cells change type up to a given
distance, or under other conditions, the differentiation process propagates
through the whole domain. When the signal diminishes hysteresis is observed
meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye
5 páginas, 4 figuras. Supplementary material for this article is available at http://dev.biologists.org/cgi/content/full/135/5/799/DC1During eye development, retinal progenitors are drawn from a multipotent, proliferative cell population. In Drosophila the maintenance of this cell population requires the function of the TALE-homeodomain transcription factor Hth, although its mechanisms of action are still unknown. Here we investigate whether members of the Meis gene family, the vertebrate homologs of hth, are also involved in early stages of eye development in the zebrafish. We show that meis1 is initially expressed throughout the eye primordium. Later, meis1 becomes repressed as neurogenesis is initiated, and its expression is confined to the ciliary margin, where the retinal stem population resides. Knocking down meis1 function through morpholino injection causes a delay in the G1-to-S phase transition of the eye cells, and results in severely reduced eyes. This role in cell cycle control is mediated by meis1 regulating cyclin D1 and c-myc transcription. The forced maintenance of meis1 expression in cell clones is incompatible with the normal differentiation of the meis1-expressing cells, which in turn tend to reside in undifferentiated regions of the retinal neuroepithelium, such as the ciliary margin. Together, these results implicate meis1 as a positive cell cycle regulator in early retinal cells, and provide evidence of an evolutionary conserved function for Hth/Meis genes in the maintenance of the proliferative, multipotent cell state during early eye development.This work was supported by grants BMC2003-06248 and BFU2006-00349/BMC from the Spanish Ministry of Education and Science, co-funded by FEDER, to F.C. J.B., M.J.T. and J.S. are supported by the Fundação para Ciência e Tecnologia, Portugal. The CABD is institutionally supported by Junta de Andalucía.Peer reviewe
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On Birthing Dancing Stars: The Need for Bounded Chaos in Information Interaction
While computers causing chaos is acommon social trope, nearly the entirety of the history of computing is dedicated to generating order. Typical interactive information retrieval tasks ask computers to support the traversal and exploration of large, complex information spaces. The implicit assumption is that they are to support users in simplifying the complexity (i.e. in creating order from chaos). But for some types of task, particularly those that involve the creative application or synthesis of knowledge or the creation of new knowledge, this assumption may be incorrect. It is increasingly evident that perfect order—and the systems we create with it—support highly-structured information tasks well, but provide poor support for less-structured tasks.We need digital information environments that help create a little more chaos from order to spark creative thinking and knowledge creation. This paper argues for the need for information systems that offerwhat we term ‘bounded chaos’, and offers research directions that may support the creation of such interface
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