“Smartphone apps are cool, but do they help me?”: A qualitative interview study of adolescents’ perspectives on using smartphone interventions to manage nonsuicidal self-injury

Nonsuicidal self-injury (NSSI) is a major mental health problem associated with negative psychosocial outcomes and it most often starts in early adolescence. Despite this, adolescents are rarely involved in informing the development of interventions designed to address their mental health problems. This study aimed to (1) assess adolescents’ needs and preferences about future interventions that are delivered through smartphones and (2) develop a framework with implications for designing engaging digital mental health interventions. Fifteen adolescent girls, aged 12– 18 years, who met diagnostic criteria for a current NSSI disorder and were in contact with mental health services, participated in semi-structured interviews. Following a reflexive thematic analysis approach, this study identified two main themes: (1) Experiences of NSSI (depicts the needs of young people related to their everyday experiences of managing NSSI) and (2) App in Context (por-trays preferences of young people about smartphone interventions and reflects adolescents’ views on how technology itself can improve or hinder engaging with these interventions). Adolescent patients expressed interest in using smartphone mental health interventions if they recognize them as helpful, relevant for their life situation and easy to use. The developed framework suggests that digital mental health interventions are embedded in three contexts (i.e., person using the interven-tion, mental health condition, and technology-related factors) which together need to inform the development of engaging digital resources. To achieve this, the cooperation among people with lived experience, mental health experts, and human computer interaction professionals is vital

INVESTIGATION OF THE COMPATIBILITY OF FASILLAR AND EFLATUNPINAR HITΤITE MONUMENTS WITH CLOSE-RANGE PHOTOGRAMMETRIC TECHNIQUE

There are two Hittite monuments in Konya whose names are Eflatunpınar and Fasıllar. Eflatunpınar is located approximately 25 km at the North of Beysehir town within Konya province in Turkey. Eflatunpınar monument is belonging to Hittite Empire Age, was known since XIX century. It is an open air temple of Hittite, 6.60 m wide and 7 m high, was built with large block stones. The second one known as Fasıllar Hittite monument lies on a hillside next to the Fasıllar village which is 16 km east of Beysehir town and it is a high relief monument which is made of basalt rock. It is commonly accepted that these two monuments had never been completely finished. J. Mellaart have suggested that Fasıllar monument was not in-situ position, it was moved from Eflatunpınar to Fasıllar village by the local people for decoration purposes. This means that ac-cording to J. Mellaart, Fasıllar monument is the part of Eflatunpınar monument. The objective of this study is to investigate whether Fasıllar monument was built for placing on the top of Eflatunpınar monument which is firstly raised a subject by J. Mellaart. For this purpose, three-dimensional (3D) digital model was created for each monument by close-range photogrammetric technique. By the help of the 3D digital models of these monuments, the unity between the monuments were investigated as an engineering approach

Gravitational Instantons from Minimal Surfaces

Physical properties of gravitational instantons which are derivable from minimal surfaces in 3-dimensional Euclidean space are examined using the Newman-Penrose formalism for Euclidean signature. The gravitational instanton that corresponds to the helicoid minimal surface is investigated in detail. This is a metric of Bianchi Type $VII_0$, or E(2) which admits a hidden symmetry due to the existence of a quadratic Killing tensor. It leads to a complete separation of variables in the Hamilton-Jacobi equation for geodesics, as well as in Laplace's equation for a massless scalar field. The scalar Green function can be obtained in closed form which enables us to calculate the vacuum fluctuations of a massless scalar field in the background of this instanton.Comment: One figure available by fax upon request. Abstract missing in original submission. Submitted to Classical and Quantum Gravit

The effects of an insertion in the 5 ' UTR of the AMCase on gene expression and pulmonary functions

Cataloged from PDF version of article.Background: Studies regarding the physiological role of acidic mammalian chitinase (AMCase) and the effects of its genetic variants on asthma have produced conflicting results. Objectives: We aimed to determine the genetic variants in the AMCase gene that could regulate the gene expression and thus influence disease severity. Methods: Genetic variants of the AMCase gene were determined by sequencing of asthmatics and healthy controls in up to -1 kb in the promoter region and exon 1 and 2. In an association study, a population of asthmatic (n = 504) and healthy Turkish children (n = 188) were genotyped for the observed SNPs. A replication study was performed in a North American adult population of patients with mild (n = 317) and severe (n = 145) asthma. The functional properties of the insertion were determined by promoter reporter assay, electromobility shift assay and transcription factor ELISA experiments. Results: Of the identified SNPs, only a ten base pair insertion (CAATCTAGGC) in the 5'UTR region of exon 2 was significantly associated with lower FEV(1) (beta = -14.63 SE = 6.241, P = 0.019) in Turkish children with asthma. However, in the adult population, the same insertion showed a trend toward higher FEV(1). The insertion was shown to have enhancer activity and the mutant probe possessing the insertion had higher binding affinity for the nuclear extracts. Conclusion: Our study shows that a ten base pair insertion in the 5'UTR region of AMCase gene may modify gene expression and thus may affect the severity of asthma. However, its effects appear to be different in different populations. (C) 2011 Elsevier Ltd. All rights reserved

Ontology-based access to temporal data with Ontop: a framework proposal

Predictive analysis gradually gains importance in industry. For instance, service engineers at Siemens diagnostic centres unveil hidden knowledge in huge amounts of historical sensor data and use it to improve the predictive systems analysing live data. Currently, the analysis is usually done using data-dependent rules that are specific to individual sensors and equipment. This dependence poses significant challenges in rule authoring, reuse, and maintenance by engineers. One solution to this problem is to employ ontology-based data access (OBDA), which provides a conceptual view of data via an ontology. However, classical OBDA systems do not support access to temporal data and reasoning over it. To address this issue, we propose a framework for temporal OBDA. In this framework, we use extended mapping languages to extract information about temporal events in the RDF format, classical ontology and rule languages to reflect static information, as well as a temporal rule language to describe events. We also propose a SPARQL-based query language for retrieving temporal information and, finally, an architecture of system implementation extending the state-of-the-art OBDA platform Ontop

Applications of Temperley-Lieb algebras to Lorentz lattice gases

Motived by the study of motion in a random environment we introduce and investigate a variant of the Temperley-Lieb algebra. This algebra is very rich, providing us three classes of solutions of the Yang-Baxter equation. This allows us to establish a theoretical framework to study the diffusive behaviour of a Lorentz Lattice gas. Exact results for the geometrical scaling behaviour of closed paths are also presented.Comment: 10 pages, latex file, one figure(by request

Inattentive Consumers in Markets for Services

In an experiment on markets for services, we find that consumers are likely to stick to default tariffs and achieve suboptimal outcomes. We find that inattention to the task of choosing a better tariff is likely to be a substantial problem in addition to any task and tariff complexity effect. The institutional setup on which we primarily model our experiment is the UK electricity and gas markets, and our conclusion is that the new measures by the UK regulator Ofgem to improve consumer outcomes are likely to be of limited impact

Two-dimensional rule language for querying sensor log data: a framework and use cases

Motivated by two industrial use cases that involve detecting events of interest in (asynchronous) time series from sensors in manufacturing rigs and gas turbines, we design an expressive rule language DslD equipped with interval aggregate functions (such as weighted average over a time interval), Allen’s interval relations and various metric constructs. We demonstrate how to model events in the uses cases in terms of DslD programs. We show that answering DslD queries in our use cases can be reduced to evaluating SQL queries. Our experiments with the use cases, carried out on the Apache Spark system, show that such SQL queries scale well on large real-world datasets