On the dynamics of vortex modes within magnetic islands

Recent work investigating the interaction of magnetic islands with micro-turbulence has uncovered the striking observation of large scale vortex modes forming within the island structure [W.A. Hornsby {\it et al.}, Phys. Plasmas {\bf 17} 092301 (2010)]. These electrostatic vortices are found to be the size of the island and are oscillatory. It is this oscillatory behaviour and the presence of turbulence that leads us to believe that the dynamics are related to the Geodesic Acoustic Mode (GAM), and it is this link that is investigated in this paper. Here we derive an equation for the GAM in the MHD limit, in the presence of a magnetic island modified three-dimensional axisymmetric geometry. The eigenvalues and eigenfunctions are calculated numerically and then utilised to analyse the dynamics of oscillatory large-scale electrostatic potential structures seen in both linear and non-linear gyro-kinetic simulations

Entrepreneurship Everywhere: Across Campus, Across Communities, and Across Borders

This paper introduces the theme of this special issue related to “Entrepreneurship Everywhere: Across Campus, Across Communities, and Across Borders.” We explore three critical points as we set up the accepted articles for the special issue. First, if we are everywhere are we anywhere? Second, we focus on the importance of collaboration. Third, we discuss the importance of strategically planning on how your efforts intervene or integrate into the wider ecosystem. Entrepreneurship is everywhere. A search of the term “entrepreneurship” on Google yields 132 million results. By comparison a search on “strategic management” yields a mere 17.2 million results. Despite the highly unscientific nature of this comparison, the results shine the light on the tremendous interest and growth in entrepreneurship and entrepreneurs. The job creation potential of small businesses and entrepreneurial firms has captured the attention of politicians from across the globe and the ideological spectrum, who frequently hale the benefits of entrepreneurial activity. Citing work by Tornatzky and Rideout (2014), the Kauffman Foundation’s (2015) “State of Entrepreneurship” address indicates that entrepreneurship programs, both curricular and noncurricular, are the fastest-growing programs on college campuses. While many large corporations are villainized, entrepreneurs and small businesses are generally held in high regard and lionized in many instances. Further, interest and growth in the topic of entrepreneurship is unbound by geography or academic discipline. Across many university campuses it is common to find multiple programs and centers dedicated to fostering and growing entrepreneurship. Programs as diverse as engineering, music, pharmacy, agriculture, art, and law are all focusing on helping their students to both engage in entrepreneurial thinking and activity. While the business school remains a key component of the entrepreneurial ecosystem on campuses across the globe, the diversity of programs has grown dramatically. This special issue seeks to highlight this expansive growth by including a diverse set of articles that point to the explosive growth of entrepreneurship and entrepreneurship programing around the world, within our communities and on college campuses. We will briefly preview each of the contributions below, but first we highlight three critical and related questions of the growth of entrepreneurship. First, if entrepreneurship is everywhere, is it truly anywhere? Second, as entrepreneurship continues to be an emphasis across levels of federal, state, and local government and as diverse university entities continue to seek to spark entrepreneurial activities, how is this best managed? Third, how is the entrepreneurial ecosystem affected by the tremendous investment and enhanced focus of universities and government entities in trying to engineer entrepreneurship

Legitimate to whom? The challenge of audience diversity and new venture legitimacy

We examine how entrepreneurs manage new venture legitimacy judgments across diverse audiences, so as to appear legitimate to the different audience groups that provide much needed financial resources for venture survival and growth. To do so, we first identify and describe the different mechanisms by which entrepreneurs can establish new venture legitimacy across diverse audiences. We then account for the institutional logics that characterize different new venture audience groups, and use this as a basis for uncovering how and why the legitimacy criteria for a new technology venture may vary depending on the audience. We then consider how leaders of entrepreneurial ventures may use framing as a means to manage legitimacy judgments across various audiences, and thereby improve their chances of accessing critical financial resources for venture survival and growth

Resistance training volume load with and without exercise displacement

Monitoring the resistance training volume load (VL) (sets × reps × load) is essential to managing resistance training and the recovery⁻adaptation process. Eight trained weightlifters, seven of which were at national level, participated in the study. VL was measured both with (VLwD) and without (VL) the inclusion of barbell displacement, across twenty weeks of training, in order to allow for comparisons to be made of these VL calculating methods. This consisted of recording the load, repetition count, and barbell displacement for every set executed. Comparisons were made between VL and VLwD for individual blocks of training, select training weeks, and select training days. Strong, statistically significant correlations (r ≥ 0.78, < 0.001) were observed between VL and VLwD between all training periods analyzed. -tests revealed statistically significant ( ≤ 0.018) differences between VL and VLwD in four of the seven training periods analyzed. The very strong relationship between VL and VLwD suggest that a coach with time constraints and a large number of athletes can potentially spare the addition of displacement. However, differences in percent change indicate that coaches with ample time should include displacement in VL calculations, in an effort to acquire more precise workload totals

The role of network density and betweenness centrality in diffusing new venture legitimacy: an epidemiological approach

To survive and grow, new ventures must establish initial legitimacy, and subsequently diffuse this legitimacy through a given population. While the notion of initial legitimacy has received substantial attention in the recent literature, diffusion has not. This work endeavors to outline the legitimacy diffusion process via drawing parallels with the field of epidemiology. Ultimately, to effectively diffuse legitimacy (and grow) a firm must gain positive judgments of appropriateness from members of a given network. Importantly, as with diseases, the characteristics of the network are critical to the diffusion process. A relatively dense network is posited to invoke a normative evaluation process by its members, and can be difficult for new ventures to access, but subsequent diffusion of new venture legitimacy can be rapid. A less dense network, on the other hand, is posited to invoke a pragmatic evaluation process by its members, and is likely easier for new ventures to access initially, but may result in lower levels of new venture legitimacy diffusion in the long run. Theoretical and practical implications are discussed

Spacecraft Conceptual Design for the 8-Meter Advanced Technology Large Aperture Space Telescope (ATLAST)

The Advanced Concepts Office at Marshall Space Flight Center completed a brief spacecraft design study for the 8-meter monolithic Advanced Technology Large Aperture Space Telescope (ATLAST-8m). This spacecraft concept provides all power, communication, telemetry, avionics, guidance and control, and thermal control for the observatory, and inserts the observatory into a halo orbit about the second Sun-Earth Lagrange point. The multidisciplinary design team created a simple spacecraft design that enables component and science instrument servicing, employs articulating solar panels for help with momentum management, and provides precise pointing control while at the same time fast slewing for the observatory

Reducing the susceptibility of lumped-element KIDs to two-level system effects

Arrays of lumped-element kinetic inductance detectors (LEKIDs) optically coupled through an antenna-coupled transmission line are a promising candidate for future cosmic microwave background (CMB) experiments. However, the dielectric materials used for the microstrip architecture are known to degrade the performance of superconducting resonators. In this paper, we investigate the feasibility of microstrip coupling to a LEKID, focusing on a systematic study of the effect of depositing amorphous silicon-nitride on a LEKID. The discrete and spatially-separated inductive and capacitive regions of the LEKID allow us to vary the degree of dielectric coverage and determine the limitations of the microstrip coupling architecture. We show that by careful removal of dielectric from regions of high electric field in the capacitor, there is minimal degradation in dielectric loss tangent of a partially covered lumped-element resonator. We present the effects on the resonant frequency and noise power spectral density and, using the dark responsivity, provide an estimate for the resulting detector sensitivity.Comment: Presented at the 18th International Workshop on Low Temperature Detectors. Published in the Journal of Low Temperature Physic

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Human cells express thousands of different surface proteins that can be used for cell classification, or to distinguish healthy and disease conditions. A method capable of profiling a substantial fraction of the surface proteome simultaneously and inexpensively would enable more accurate and complete classification of cell states. We present a highly multiplexed and quantitative surface proteomic method using genetically barcoded antibodies called phage-antibody next-generation sequencing (PhaNGS). Using 144 preselected antibodies displayed on filamentous phage (Fab-phage) against 44 receptor targets, we assess changes in B cell surface proteins after the development of drug resistance in a patient with acute lymphoblastic leukemia (ALL) and in adaptation to oncogene expression in a Myc-inducible Burkitt lymphoma model. We further show PhaNGS can be applied at the single-cell level. Our results reveal that a common set of proteins including FLT3, NCR3LG1, and ROR1 dominate the response to similar oncogenic perturbations in B cells. Linking high-affinity, selective, genetically encoded binders to NGS enables direct and highly multiplexed protein detection, comparable to RNA-sequencing for mRNA. PhaNGS has the potential to profile a substantial fraction of the surface proteome simultaneously and inexpensively to enable more accurate and complete classification of cell states